9 research outputs found

    Role of organic carbon and nitrogen of mineral waters in their immunomodulating effects at female rats

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    Popovych Igor, Mysula Igor, Popovych Andriy, Mysula Yuriy, Sydliaruk Nataliya, Bilas Volodymyra, Zukow Walery. Role of organic carbon and nitrogen of mineral waters in their immunomodulating effects at female rats. Journal of Education, Health and Sport. 2021;11(9):886-894. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.09.104 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2021.11.09.104 https://zenodo.org/record/5856299 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.09.2021. Revised: 20.09.2021. Accepted: 30.09.2021. ROLE OF ORGANIC CARBON AND NITROGEN OF MINERAL WATERS IN THEIR IMMUNOMODULATING EFFECTS AT FEMALE RATS Igor Popovych1, Igor Mysula2, Andriy Popovych1, Yuriy Mysula2, Nataliya Sydliaruk2, Volodymyra Bilas1, Walery Zukow3* 1OO Bohomolets’ Institute of Physiology, Kyїv, Ukraine 2IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine 3Nicolaus Copernicus University, Torun, Poland *[email protected] Abstract Background. Drinking mineral water is one of the ethnopharmacologic factors. Organic substances, despite their presence in all drinking mineral waters, are still considered to be active only in the water of Naftussya type (which, due to mineralization less than 1 g/L, are not formally mineral), whereas the physiological activity of true mineral waters (which mineralization is greater than 1-2 g/L) are associated with electrolytes and trace elements. Previously, we identified the role of organic carbon and nitrogen of mineral waters in their effects on certain metabolic and neuro-endocrine parameters. The purpose of this study is to clarify the role of organic substances of same mineral waters in their effects on immunity parameters. Material and methods. Experiment was performed on 48 healthy female Wistar rats 240-290 g divided into 5 groups. Animals of the first group for 6 days administered a single tap water through the tube at a dose of 1,5 mL/100 g of body mass. In the second group we administered the water Naftussya from the Truskavets’ layer (Galychyna, Ukraine), in the third group the water Sophiya of the Truskavets’ field. The rats of the fourth group received the native water from the Hertsa (Bucovyna, Ukraine) field, and the last group received its artificial salt analogue. The day after the completion of the drinking course in all rats immunne parameters were registered. Results. On the basis of the correlation analysis with step-by-step exclusion, 9 immune parameters (Endotheliocytes of Thymus, Spleen Mass Index, Entropy of Splenocytogram, Natural Killers, B- and 0-Lymphocytes, Rod-shaped Neutrophils, Phagocytic Index and Microbian Count of Monocytes of Blood) are included in the regressive model for organic nitrogen (R=0,818) and 6 parameters (Endotheliocytes of Thymus, Fibroblastes and Reticulocytes of Spleen, Pan-Lymphocytes, Microbian Count of Neutrophils and Phagocytic Index of Monocytes of Blood) for organic carbon (R=0,690). Together, the organic components of the chemical composition of loading fluids determine their effect on the immune parameters by 77%. Conclusion. Organic substances of mineral waters play an essential role in their effects on the immune parameters of female rats. Key words: Mineral waters, organic carbon and nitrogen, female rats, immunity

    Features of neuro-endocrine and immune reactions to various water-salt loads in female rats

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    Gozhenko Olena A, Zavidnyuk Yuriy V, Korda Mykhaylo M, Mysula Igor R, Klishch Ivan M, Zukow Walery, Popovych Igor L. FEATURES OF NEURO-ENDOCRINE AND IMMUNE REACTIONS TO VARIOUS WATER-SALT LOADS IN FEMALE RATS. Journal of Education, Health and Sport. 2018;8(9):11-31. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1323491 http://ojs.ukw.edu.pl/index.php/johs/article/view/5729 https://pbn.nauka.gov.pl/sedno-webapp/works/872545 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Author(s) 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.06.2018. Revised: 28.06.2018. Accepted: 30.07.2018. FEATURES OF NEURO-ENDOCRINE AND IMMUNE REACTIONS TO VARIOUS WATER-SALT LOADS IN FEMALE RATS Olena A Gozhenko1, Yuriy V Zavidnyuk1,2, Mykhaylo M Korda2, Igor R Mysula2, Ivan M Klishch2, Walery Zukow3, Igor L Popovych4 1Ukrainian Scientific Research Institute of Transport Medicine, Odesa, Ukraine, [email protected] 2IY Horbachevs’kyi State Medical University, Ternopil’, Ukraine, [email protected] 3Nicolaus Copernicus University, Torun, Poland, [email protected] 4OO Bohomolets’ Institute of Physiology, Kyiv, Ukraine, [email protected] Abstract Background. Previously, we have shown that the weekly load of rats with water-salt solutions of different chemical compositions causes both general and specific reactions of the parameters of metabolism. The purpose of this study is to identify under these conditions specific neuroendocrine and immune responses. Materials and methods. Experiment was performed on 58 healthy female Wistar rats 240-290 g divided into 6 groups. Animals of the first group remained intact, using tap water from drinking ad libitum. Instead, the other rats received the same tap water as well as waters Sophiya, Naftussya, Gertsa and its artificial salt analogue through the probe at a dose of 1,5 mL/100 g of body mass for 6 days. The day after the completion of the drinking course in all rats some neuroendocrine and immune parameters were registered. Results. The method of discriminant analysis revealed 29 parameters of the neuroendocrine-immune complex (10 of them reflect the neuroendocrine regulation, 4 thymus mass and thymocytogram elements, 5 elements of splenocytogram, 10 elements of immunocytogram and leukocytogram of blood and parameters of phagocytosis), according to which the reaction on various water-salt loads are identified with an accuracy of 98.3%. Conclusion. The peculiarities of the reactions of the parameters of the neuroendocrine-immune complex are due to the content of water in sulfate, bicarbonate and magnesium, as well as organic carbon and nitrogen. Key words. Water-salt loads, neuroendocrine and immune parameters, female rats.Gozhenko Olena A, Zavidnyuk Yuriy V, Korda Mykhaylo M, Mysula Igor R, Klishch Ivan M, Zukow Walery, Popovych Igor L. FEATURES OF NEURO-ENDOCRINE AND IMMUNE REACTIONS TO VARIOUS WATER-SALT LOADS IN FEMALE RATS. Journal of Education, Health and Sport. 2018;8(9):11-31. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1323491 http://ojs.ukw.edu.pl/index.php/johs/article/view/5729 https://pbn.nauka.gov.pl/sedno-webapp/works/87254

    Similarity Of Effects On EEG Parameters Of Aramaic, Greek Catholic And Krishnaic Prayers

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    Popovych Igor L., Gozhenko Anatoliy I., Babelyuk Valeriy Ye., Zukow Walery, Muszkieta Radosław, Korolyshyn Tetyana A., Dubkova Galyna I., Klishch Ivan M., Mysula Igor R., Bilas Volodymyra R., Flyunt Igor-Severyn S., Fil’ Vitaliy M., Barylyak Liliya G. Similarity Of Effects On EEG Parameters Of Aramaic, Greek Catholic And Krishnaic Prayers. Pedagogy and Psychology of Sport. 2020;6(1):121-137. elSSN 2450-6605. DOI http://dx.doi.org/10.12775/PPS.2020.06.01.010 https://apcz.umk.pl/czasopisma/index.php/PPS/article/view/PPS.2020.06.01.010 https://zenodo.org/record/4130121 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2020; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.05.2020. Revised: 26.05.2020. Accepted: 28.05.2020. Similarity Of Effects On EEG And HRV Parameters Of Aramaic, Greek Catholic And Krishnaic Prayers Igor L. Popovych1,6, Anatoliy I. Gozhenko1, Valeriy Ye. Babelyuk2, Walery Zukow3, Radosław Muszkieta3, Tetyana A. Korolyshyn2, Galyna I. Dubkova2, Ivan M. Klishch4, Igor R. Mysula4, Volodymyra R. Bilas2, Igor-Severyn S. Flyunt5, Vitaliy M. Fil’5, Liliya G. Barylyak1 1Ukrainian Scientific Research Institute of Medicine for Transport, Odesa, Ukraine [email protected] 2Clinical Sanatorium „Моldоvа”, Truskavets’, Ukraine [email protected] 3Nicolaus Copernicus University, Torun, Poland [email protected] 4Ivan Horbachevs’kyi National Medical University, Ternopil’, Ukraine 5Ivan Franko Pedagogical University, Drohobych, Ukraine 6Kozyavkin International Rehabilitation Clinic, Truskavets’, Ukraine [email protected] Abstract Background. The effect on the electroencephalogram of Meditation is the subject of numerous studies. Instead, Prayer is for some reason deprived of the attention of researchers. But even these few articles are about Islam. We treat all confessions with equal respect, convinced that God is one, but He has many names and many paths lead to Him. One approach to confirm this belief may be to compare the EEG's immediate response to the Prayers of different confessions. This determined the purpose of this study. Material and Methods. The object of observation were 4 men: Greek Catholic priest, head of the Church Brotherhood, the supporter of Krishna, and the first author to memorize the authentic Lord's Prayer in Aramaic. Іn the morning in basale terms (eyes closed) recorded EEG monopolar in 16 loci by 10-20 international system, with the reference electrodes A and Ref on the tassels ears. Among the options considered the average EEG amplitude, frequency, frequency deviation, index, coefficient of asymmetry as well as absolute and relative power spectrum density (PSD) of basic rhythms: β (35÷13 Hz), α (13÷8 Hz), θ (8÷4 Hz) and δ (4÷0,5 Hz) in all loci. In addition, calculated laterality index for PSD each rhythm and the Entropy of relative PSD for each locus EEG. After initial testing, EEG (4-7 times for 25 seconds) was again registered for the next 7 minutes. At the same time, the participants of the study silently said the Prayer: the author in Aramaic, Father and Brother in Ukrainian “Our Father …”, and Krishnait in Sanskrit “Hare Krishna …”. Results. EEG parameters were found, according to which the condition of all four study participants before and during Prayer differed significantly. The neurotropic effects of Prayers are manifested in two inhibitory and three activating patterns. The first inhibitory pattern reflects the decrease in elevated and upper limit levels of PSD of θ-and δ-rhythm in frontal loci and the second reflects decrease in normal PSD levels of β-and θ-rhythm in the frontal, central, temporal and parietal loci. The first enhancing pattern reflects a small increase in normal levels of β-rhythm index and asymmetry and PSD entropy in locus C3, as well as a further increase in elevated δ-rhythm PSD levels in loci P3 and T3. The second enhancing pattern reflects the slight increase in normal PSD levels of θ-rhythm in loci T3, T5, T6, O2 and α-rhythm in locus T5, as well as their indices and entropy PSD in locus O2. The third enhancing pattern reflects a slight increase in amplitude and PSD of α-rhythm in central, frontal, temporal and occipital loci. Conclusion. Aramaic, Greek Catholic and Krishnaic Prayers cause the similar immediate changes in a number of parameters of the electroencephalogram. Key words: Aramaic, Greek Catholic, Krishnaic Prayers, electroencephalogram

    Role of organic carbon and nitrogen of mineral waters in their metabolic effects at female rats

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    Background. Organic substances, despite their presence in all drinking mineral waters, are still considered to be active only in the water of Naftussya type (which, due to mineralization less than 1 g/L, are not formally mineral), whereas the physiological activity of true mineral waters (which mineralization is greater than 1-2 g/L) are associated with electrolytes and trace elements. The purpose of this study was to clarify the role of organic carbon and nitrogen of mineral waters in their effects on certain parameters of metabolism. Material and Methods. Experiment was performed on 48 healthy female Wistar rats 240-290 g divided into 5 groups. Animals of the first group for 6 days administered a single tap water through the probe at a dose of 1,5 mL/100 g of body mass. In the second group we administered the water Naftussya from the Truskavets’ layer, in the third group the water Sophiya of the Truskavets’ field. The rats of the fourth group received the native water from the Gertsa (Bucovyna) field, and the last group its artificial salt analogue. The day after the completion of the drinking course in all rats some metabolic parameters were registered. Results. On the basis of the correlation analysis with step-by-step exclusion, four metabolites of blood as well as five metabolites of urine are included in the regressive model for organic carbon (R=0,697; R2=0,486; Adjusted R2=0,347; F(10,4)=3,5; p=0,0025). Organic nitrogen of mineral waters affects five metabolic parameters of urine only, but with approximately the same force (R=0,621; R2=0,385; Adjusted R2=0,312; F(5,4)=5,3; p=0,0008). Conclusion. Organic substances of mineral waters play an essential role in their effects on the parameters of metabolism

    General non-specific metabolic, neuroendocrine and immune reactions to various water-salt loads in female rats

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    Background. This article begins with a series of articles on the effects on parameters of water-salt, nitrous and lipid metabolism, as well as the neuroendocrine-immune complex of mineral water, extracted from the bore located in the city Gertsa (Bukovyna, Ukraine). The chemical analysis prompted us to use waters Sophiya and Naftussya from spa Truskavets’ as a reference as well as an artificial salt analogue of Gertsa water, which contains no organic matter or trace elements. Materials and methods. Experiment was performed on 58 healthy female Wistar rats 240-290 g divided into 6 groups. Animals of the first group remained intact, using tap water from drinking ad libitum. Instead, the other rats received the same tap water as well as waters Sophiya, Naftussya, Gertsa and its artificial salt analogue through the probe at a dose of 1,5 mL/100 g of body mass for 6 days. The day after the completion of the drinking course in all rats the parameters of metabolism and neuroendocrine-immune complex were registered. Results. Screening registered parameters found 42 among them who in rats subjected to water-salt loads, significantly different from that of intact rats, but on average the same group of animals that received liquids with different mineralization and chemical composition. Conclusion. Takes place nonspecific (general) reaction neuroendocrine-immune complex and metabolism in water-salt load as such, regardless of the specific chemical composition of fluids applied

    Relationships between caused by Kozyavkin© method changes in parameters of manual function and electroencephalogram, heart rate variability as well as gas discharge visualization in children with spastic form of cerebral palsy

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    Background. Earlier we reported that in children with spastic forms of cerebral palsy (SFCP) after two-week course of rehabilitation by Kozyavkin© method reducing neural component of muscle tone (NCMT) stated in 79,3% cases while in 13,8% cases changes were not detected and in 2 children it increased. We hypothesized that such a variety of changes in NCMT is due to ambiguous changes in the background activity of the nerve centers. Aim: analysis of relationships between changes (Ch) in NCMT as well as manual functional tests, on the one hand, and parameters of EEG, HRV as well as Gas Discharge Visualization (GDV), on the other hand. Material and research methods. The object of observations were 14 children (6 girls and 8 boys) aged 8÷15 years with SFCP. State motor development at GMFCS was on II÷IV level. Functional status of the hand with MACS was at II÷III level. The estimation of hand function carried out by Dynamometry (D), Box and Block Test (B&B) and Nine Hole Peg Test (NHP). We registered also NCMT by device “NeuroFlexor” (Aggero MedTech AB, Sweden), HRV and EEG simultaneosly by hardware-software complex “Cardiolab+VSR” and “NeuroCom Standard” respectively (KhAI Medica, Kharkiv, Ukraine) as well as GDV by “GDV Chamber” (“Biotechprogress”, St-Pb, RF). Results. After two-week course of rehabilitation at 9 children NCMT reduced from 19,8±3,4 to 12,3±2,8 Newtons (Ch: -7,5±2,0 N), at 3 children NCMT taked 8,2±3,3 before and 7,9±3,5 after rehabilitation (Ch: -0,3±0,3 N) while at one girl NCMT increased from 15,1 to 17,9 N and at one boy from 6,1 to 19,4 N. Manual functional tests also changed ambiguously. The Ch in NCMT are correlated with Ch in parameters HRV&EEG (R2=0,786). The Ch in functional tests of Left hand are correlated with Ch in parameters HRV&EEG to the same extent: the level of R2 is for D 0,799, for NHP 0,773 and for B&B 0,708. Instead, for the Right hand, the correlation is stronger: R2 is 0,973, 0,792 and 0,978 respectively. As regards GDV parameters, connections are weaker, but they are also stronger for the Right hand: R2 is 0,706 vs 0,462 for B&B and 0,679 vs 0,405 for NHP but not for D (0,719 and 0,709). The Ch in NCMT are correlated with Ch in parameters GDV also weaker (R2=0,556). In its turn, changes in GDV parameters are very closely related to changes in parameters of both HRV (R2=0,999) and EEG (R2=0,998). Conclusion. In children with spastic forms of cerebral palsy caused by Kozyavkin© method changes in manual functional tests and neural component of muscle tone are determined by changes in parameters of EEG and HRV as well as GDV

    Similarity Of Effects On EEG And HRV Parameters Of Aramaic, Greek Catholic And Krishnaic Prayers

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    The object of observation were 4 men: Greek Catholic priest Father Volodymyr, head of the Church Brotherhood Ivan, a supporter of Krishna Victor, and your obedient servant, the first author to memorize the authentic Lord's Prayer in Aramaic. Results. The neurotropic effects of Prayer are manifested in two inhibitory and three activating patterns. The first inhibitory pattern reflects the decrease in elevated and upper limit levels of SPD of θ-and δ-rhythm in frontal loci and the second - decrease in normal SPD levels of β-and θ-rhythm in the frontal, central, temporal and parietal loci. The first activating pattern reflects a small increase in normal levels of β-rhythm index and asymmetry and SPD entropy in locus C3, as well as a further increase in elevated δ-rhythm SPD levels in loci P3 and T3. The second pattern reflects the slight increase in normal SPD levels of θ-rhythm in loci T3, T5, T6, O2 and α-rhythm in locus T5, as well as their indices and entropy SPD in locus O2. The third pattern reflects a slight increase in amplitude and SPD of α-rhythm in central, frontal, temporal and occipital loci

    Gas Discharge Visualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects

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    Babelyuk Valeriy Y., Popovych Igor L., Gozhenko Anatoliy I., Dubkova Galyna I., Kozyavkina Olga V., Korolyshyn Tetyana A., Babelyuk Nazariy V., Kovbasnyuk Marta M., Fihura Oksana A., Dobrovolskyi Yuriy G., Zukow Walery, Yanchij Roman I. Gas Discharge Visualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects. Odesa. Feniks; 2023: 200. ISBN 978-1-4478-8957-1. DOI http://dx.doi.org/10.5281/zenodo.7535880 The monograph highlights the results of priority clinical-physiological studies of the relationships between gas discharge visualization (electrophotonic imaging, kirlianography) parameters, on the one hand, and electroencephalograms, heart rate variability, immunograms, phagocytosis, the content of the main adaptation hormones (cortisol, aldosterone, testosterone, triiodothyronine, calcitonin) in the blood as well as acupuncture points - on the other hand. It is shown that the GDV/EPI method reliably reflects the state of the body's neuro-endocrine-immune complex as well as others parameters and has the right to take its place in the arsenal of physiological/biophysical methods. For biophysicists, physiologists, psychophysiologists, endocrinologists, immunologists, medical rehabilitation specialists. Bohomolets’ Institute of Physiology National Academy of Sciences, Kyїv, Ukraine Ukrainian Scientific Research Institute of Medicine of Transport Ministry of Health of Ukraine, Odesa Kozyavkin International Rehabilitation Clinic, Truskavets’, Ukraine Yuriy Fed’kovych National University Ministry of Science and Education, Chernivtsi, Ukraine Editors Valeriy Y. Babelyuk Igor L. Popovych GAS DISCHARGE VISUALIZATION (ELECTROPHOTONIC IMAGING, KIRLIANOGRAPHY). THEORETICAL AND APPLIED ASPECTS ODESA FENIKS 2023 Authors Valeriy Y. Babelyuk, MD, PhD; Clinical sanatorium “Moldova”, Truskavets’; UkrSR Institute of Medicine of Transport [email protected] Igor L. Popovych, MD, PhD, senior res. fel.; Bohomolets’ Institute of Physiology; Kozyavkin International Rehabilitation Clinic; UkrSR Institute of Medicine of Transport [email protected] Anatoliy I. Gozhenko, MD, DS, Prof.; UkrSR Institute of Medicine of Transport [email protected] Galyna I. Dubkova, MD, PhD; Clinical sanatorium “Moldova”, Truskavets’ [email protected] Olga V. Kozyavkina, MD, PhD; Kozyavkin International Rehabilitation Clinic [email protected] Tetyana A. Korolyshyn, MD; UkrSR Institute of Medicine of Transport; Bohomolets’ Institute of Physiology [email protected] Nazariy V. Babelyuk, MD; Clinical sanatorium “Moldova”, Truskavets’ Marta M. Kovbasnyuk, PhD, senior res. fel.; Bohomolets’ Institute of Physiology [email protected] Oksana A. Fihura, MD; UkrSR Institute of Medicine of Transport; Ivan Franko State Pedagogical University, Drohobych, Ukraine [email protected] Yuriy G. Dobrovolskyi, DS, Prof. ass.; Yuriy Fed’kovych National University [email protected] Walery Zukow, MD, DS, Prof. ass.; Nicolaus Copernicus University, Torun, Poland [email protected] Roman I. Yanchij, DS, Prof.; Bohomolets’ Institute of Physiology [email protected] We dedicate the monograph to the 115th anniversary of the birth of the Luminary of Neurophysiology Academician Philip Nikolayevich Serkov (1908-2011) with gratitude for the support of the Truskavetsian Scientific School Recommended for publication by the Academic Council of Bohomolets’ Institute of Physiology National Academy of Sciences of Ukraine (protocol No. 13 dated 12/22/2022) Reviewers: Regeda Mykhaylo S., MD, DS, Prof, head of the department of pathophysiology of the Danylo Halyts’kyi National Medical University, L’viv, Ukraine Vastyanov Ruslan S., MD, DS, Prof, head of the department of general and clinical pathophysiology named after VV Podvysotskyi of the National Medical University, Odesa, Ukraine Babelyuk VY & Popovych IL [editors]. Gas Discharge Visualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects: monograph / Babelyuk VY, Popovych IL, Gozhenko AI, Dubkova GI, Kozyavkina OV, Korolyshyn TA, Babelyuk NV, Kovbasnyuk MM, Fihura OA, Dobrovolskyi YG, Zukow W, Yanchij RI. Odesa. Feniks; 2023: 186. Babelyuk Valeriy Y., Popovych Igor L., Gozhenko Anatoliy I., Dubkova Galyna I., Kozyavkina Olga V., Korolyshyn Tetyana A., Babelyuk Nazariy V., Kovbasnyuk Marta M., Fihura Oksana A., Dobrovolskyi Yuriy G., Zukow Walery, Yanchij Roman I. Gas Discharge Visualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects. Odesa. Feniks; 2023: 200. ISBN 978-1-4478-8957-1. DOI http://dx.doi.org/10.5281/zenodo.7535880 The monograph highlights the results of priority clinical-physiological studies of the relationships between gas discharge visualization (electrophotonic imaging, kirlianography) parameters, on the one hand, and electroencephalograms, heart rate variability, immunograms, phagocytosis, the content of the main adaptation hormones (cortisol, aldosterone, testosterone, triiodothyronine, calcitonin) in the blood as well as acupuncture points - on the other hand. It is shown that the GDV/EPI method reliably reflects the state of the body's neuro-endocrine-immune complex as well as others parameters and has the right to take its place in the arsenal of physiological/biophysical methods. For biophysicists, physiologists, psychophysiologists, endocrinologists, immunologists, medical rehabilitation specialists. ISBN 978-1-4478-8957-1 DOI http://dx.doi.org/10.5281/zenodo.7535880 © Bohomolets’ Institute of Physiology, Kyїv, 2023 © Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, 2023 © Kozyavkin International Rehabilitation Clinic, Truskavets’, 2023 © Yuriy Fed’kovych National University, Chernivtsi, 2023 © Authors ISBN 978-1-4478-8957-1 DOI http://dx.doi.org/10.5281/zenodo.7535880 INTRODUCTION (Babelyuk VY, Popovych IL) 6 CHAPTER 1 (Babelyuk VY, Popovych IL, Gozhenko AI, Yanchij RI) REVIEWS Biofield science and healing 8 Biofield devices 15 Application of electrophoton capture (EPC) analysis based on gas discharge visualization (GDV) technique in medicine 18 OWN RESULTS. THEORETICAL ASPECTS CHAPTER 2 (Babelyuk VY, Popovych IL, Dubkova GI) PILOT STUDIES 27 CHAPTER 3 (Babelyuk VY, Popovych IL, Dubkova GI, Gozhenko AI, Korolyshyn TA) CAUSAL RELATIONSHIPS BETWEEN THE PARAMETERS OF GAS DISCHARGE VISUALIZATION AND PRINCIPAL NEUROENDOCRINE FACTORS OF ADAPTATION 45 CHAPTER 4 (Babelyuk VY, Popovych IL, Gozhenko AI, Dubkova GI, Zukow W) CAUSAL RELATIONSHIPS BETWEEN THE PARAMETERS OF GAS DISCHARGE VISUALIZATION AND IMMUNITY 62 CHAPTER 5 (Babelyuk VY, Popovych IL, Gozhenko AI, Dubkova GI, Kovbasnyuk MM, Zukow W) CAUSAL RELATIONSHIPS BETWEEN THE PARAMETERS OF GAS DISCHARGE VISUALIZATION AND PHAGOCYTOSIS AS WELL AS LEUKOCYTOGRAM 75 CHAPTER 6 (Babelyuk VY, Popovych IL, Gozhenko AI, Dubkova GI, Korolyshyn TA, Zukow W) PARAMETERS OF GAS DISCHARGE VISUALIZATION CORRELATED WITH PARAMETERS OF ACUPUNCTURE POINTS, EEG, HRV AND HORMONES OWN RESULTS. APPLIED ASPECTS 87 CHAPTER 7 (Babelyuk VY, Popovych IL, Dobrovolskyi YG, Gozhenko AI, Dubkova GI, Korolyshyn TA, Babelyuk NV, Zukow W) REACTIONS OF GDV PARAMETERS TO TRANSCUTANEOUS ELECTRICAL STIMULATION BY DEVICES “VEB-1” AND “VEB-2” 112 CHAPTER 8 (Babelyuk VY, Popovych IL, Fihura OA, Gozhenko AI, Dubkova GI, Korolyshyn TA, Zukow W) REACTIONS OF GDV PARAMETERS TO TAKING OF NAFTUSSYA BIOACTIVE WATER AND PHYTOADAPTOGEN 130 CHAPTER 9 (Babelyuk VY, Popovych IL, Kozyavkina OV, Dubkova GI, Korolyshyn TA, Zukow W) REACTIONS OF GDV PARAMETERS OF CHILDREN WITH CEREBRAL PALSY TO TREATMENT BY KOZYAVKIN© METHOD 142 CONCLUSION (Babelyuk VY, Popovych IL, Dobrovolskyi YG) REFERENCES 169 INTRODUCTION Advances in biophysics, biology, functional genomics, neuroscience, psychology, psychoneuroimmunology, and other fields suggest the existence of a subtle system of “biofield” interactions that organize biological processes from the subatomic, atomic, molecular, cellular, and organismic to the interpersonal and cosmic levels. Biofield interactions may bring about regulation of biochemical, cellular, and neurological processes through means related to electromagnetism, quantum fields, and perhaps other means of modulating biological activity and information flow. The biofield paradigm, in contrast to a reductionist, chemistry-centered viewpoint, emphasizes the informational content of biological processes; biofield interactions are thought to operate in part via low-energy or “subtle” processes such as weak, nonthermal electromagnetic fields (EMFs) or processes potentially related to consciousness and nonlocality. Biofield interactions may also operate through or be reflected in more well-understood informational processes found in EEG and ECG data. Recent advances have led to the development of a wide variety of therapeutic and diagnostic biofield devices, defined as physical instruments best understood from the viewpoint of a biofield paradigm [Muehsam D et al, 2015]. Biofield devices comprise physical instruments that may be most clearly understood from the viewpoint of a biofield paradigm, and a large and diverse number of devices have been developed to measure or manipulate biofield interactions. These include both diagnostic devices (to measure biofield properties) and therapeutic devices (to manipulate biofield interactions). The study of biofield devices is at a nascent stage of development, and much further research is needed to determine clinical efficacy and elucidate the underlying mechanisms of action for many of the devices mentioned here. The biofield devices operate through a variety of modalities rather than a single mechanism. Some biofield devices function through well-understood mechanisms and are already widely used in clinical settings: for example, electroencephalography (EEG)- and electrocardiography (ECG)-based heart rate variability (HRV). Other devices appear to operate through mechanisms that are novel or incompletely understood. However, all of these devices share a common property: rather than functioning primarily in a reductionist, chemistry-centered manner, biofield devices function via the informational content of biological processes and can interact via low-energy or “subtle” processes, including those potentially related to consciousness and nonlocality [Muehsam D et al, 2015]. Here Muehsam D et al [2015] provide a brief overview of the broad categories of biofield devices, with the goal being to stimulate further discussion and research. Authors describe those devices for which thay deemed that sufficient evidence exists to warrant mention. They chose to focus upon devices for which peer-reviewed scientific reports suggesting efficacy are available rather than conference proceedings or manufacturers' white papers. However, in the few cases that specific devices with sufficient promise and relevance lacked a peer-reviewed basis, authors have presented whatever evidence was available. Here, devices are organized according to mode of operation and these modalities include electromagnetic field (EMF)-light, EMF-heat, EMF-nonthermal, electrical current, vibration and sound, physical and mechanical, intentionality and nonlocality, gas and plasma, and other (mode of operation not well understood). Muehsam D et al [2015] deemed that gas discharge visualization (GDV) is an important example of the use of plasma in biofield science. Back in 1880 Nikola Tesla demonstrated that when placing the man in the high-frequency field around the body there is a bright glow [cit. by Korotkov KG, 2001]. In 1892 Nardkevych-Yodko YO recorded glow human hands on photographic plate [cit. by Ciesielska I, 2009]. However, a well-known method of "high-frequency photography" was due to spouses Kirlian SD&VH who in 1939 independently discovered this phenomenon [Kirlian SD & Kirlian VKh, 1961], later called "Kirlian’s effect". This technique has been called corona discharge photography [Boyers DG & Tiller WA, 1973], electrophotography [Earle L, 1975], electrography [Konikiewicz LW, 1979], GDV [Bankovskii NG et al, 1986]. In 1996 Korotkov KG created a new scientific approach, based on the digital videotechnics, modern electronics and computer processing quantitative data, called as method gas discharge visualization (GDV bioelectrography). Parallel uses the terms Kirlianography and Electrophotonic imaging (EPI) [Korotkov KG, 2001; 2007; 2014; Korotkov KG et al, 2002; Wisneski LA & Anderson L, 2009; Jakovleva E & Korotkov K, 2013]. Method of GDV, essence of which consists in registration of photoelectronic emission of skin, induced by high-frequency electromagnetic impulses, allows to estimate integrated psycho-somatic state of organism. The first base parameter of GDV is Area of Gas Discharge Image (GDI) in Right, Frontal and Left projections registered both with and without polyethylene filter. The second base parameter is a coefficient of form/shape (ratio of square of length of external contour of GDI toward his area), which characterizes the measure of serration/fractality of external contour. The third base parameter of GDI is Entropy, id est measure of chaos. It is considered that GDI, taken off without filter, characterizes the functional changes of organism, and with a filter characterizes organic changes. Program estimates also Energy and Asymmetry of virtual Chakras [Korotkov KG, 2001; 2007; 2014]. Nearly 1000 papers have been published (mostly in Russian) on GDV research and a few hundred more in the West. These intriguing data suggest that informatics based upon biofield measurement devices such as the GDV may be useful for gaining deeper understanding of disease states and guiding practitioners and their patients towards states of greater wellness [Muehsam D et al, 2015]. Without regard to the wideuse enough of method in medicine, psychology, valeology and others like that, he yields to the just criticizing for an insufficient physiology ground. There fore we put before itself sweep to analyse relationships between the parameters of GDV - from one side, and by the row of neurodynamics, endocrine, immune. psychophysiological, and other parameters - on the other hand. REFERENCES Adams DS, Tseng AS, Levin M. Light-activation of the Archaerhodopsin H+-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo. Biol Open. 2013; 2(3): 306–313. Aharonov Y, Bohm D. Significance of electromagnetic potentials in the quantum theory. Phys Rev. 1959; 115(3): 485–491. Akmayev PG. Modern understanding of the interactions of regulatory systems: the nervous, endocrine and immune [in Russian]. Uspekhi fiziologicheskikh nauk. 1996; 27(1): 3-20. Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ. Pоwer spectrum analysis rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science (NY). 1981; 213(4504): 220-222. Albrecht-Buehler G. Rudimentary form of cellular “vision”. Proc Natl Acad Sci USA. 1992; 89(17): 8288–8292. Aldenderfer MS, Blashfield RK. Cluster analysis (Second printing, 1985) [trans. from English in Russian]. In: Factor, Discriminant and Cluster Analysis. Moskva. Finansy i Statistika; 1989: 139-214. Alyeksyeyev OI, Popovych IL, Panassyuk YM, Barylyak LG, Sarancha SM, Shumakov MF. Adaptogens and radiation [in Ukrainian]. Kyїv. Naukova dumka; 1996: 126. Aspect A, Grangier P, Roger G. Experimental realization of Einstein-Podolsky-Rosen-Bohm Gedankenexperiment: A new violation of Bell's inequalities. Phys Rev Lett. 1982; 49(2): 91–94. Babeluk VE. The patent of Ukraine for utility model 105875 Portable device for electrotherapy and stimulation, 2016. Babelyuk NV, Babelyuk VYe, Dubkowa GI, Kikhtan VV, Musiyenko VY, Hubyts’kyi VY, Dobrovolsky YG, Korsunskyi IH, Kovbasnyuk MM, Korolyshyn TA, Popovych IL. Influence of the course of electrostimulation by the device "ES-01.9 WEB" on some functional systems of the organism of practically healthy men [in Ukrainian]. In: Proceedings VIII Scientific Conference "Issues of pathology in conditions of extreme factors action on the body" (Ternopil’, 1-2 October 2015). Ternopil’. 2015: 5-6. Babelyuk NV, Babelyuk VYe, Dubkowa GI, Kikhtan VV, Musiyenko VY, Hubyts’kyi VY, Dobrovolsky YG, Korsuns’kyi IH, Kovbasnyuk MM, Korolyshyn TA, Popovych IL. Modulation of functional systems of practically healthy men by the course of electrostimulation [in Ukrainian]. In: IX International symposium “Actual problems of biophysical medicine” (Kyїv, 12-15 May 2016). Кyїv. OO Bohomolets’ Institute of Physiology; 2016: 10-11. Babelyuk NV, Babelyuk VYe, Dubkowa GI, Korolyshyn TA, Kikhtan VV, Dobrovolsky YG, Korsuns’kyi IH, Kovbasnyuk MM. Electrical stimulation with the device "ES-01.9 WEB" activates some functional systems of the body of practically healthy men [in Ukrainian]. In: Valeology: current status, trends and persrectives of development. Abstracts. XIV Intern. scient. and practical. conf. (Kharkiv-Drohobych, 14-16 April 2016). Kharkiv. VN Karazin KhNU; 2016: 198-200. Babelyuk NV. Electrostimulation with the devices "VEB-1" and "VEB-2" causes almost identical changes in the parameters of gas-discharge visualization. Experimental and Clinical Physiology and Biochemistry. 2020; 90(2): 5-13. Babelyuk V, Dobrovolsky Yu, Korsunsky I, Kuzenko V, Popovych I, Zukow W. The algorithm of the electric stimulator VEB-1 software operation. Journal of Education, Health and Sport. 2020; 10(5): 403-409. Babelyuk VE, Babelyuk NV, Popovych IL, Gozhenko AI, Kyrylenko IG, Korolyshyn TA, Dubkova GI, Kovbasnyuk MM, Hubyts’kyi VY, Kikhtan VV, Musiyenko VY, Dobrovolsky YG, Korsunskyi IH, Zukow W. Effects of transcutaneous electrical stimulation with the device “VEB” ® on the human body. Journal of Education, Health and Sport. 2022; 12(2): 313-335. Babelyuk VE, Gozhenko AI, Dubkova GI, Babelyuk NV, Zukow W, Kovbasnyuk MM, Popovych IL. Causal relationships between the parameters of gas discharge visualization and principal neuroendocrine factors of adaptation. Journal of Physical Education and Sport. 2017; 17(2): 624-637. Babelyuk VY, Babelyuk NV, Popadynets’ OO, Dubkova GI, Muszkieta R, Zukow W. Relationships between the entropy of gas-discharge image and the entropies of EEG, HRV, immunocytogram and leukocytogram. In: Mater of the XII All-Ukrainian Sci-Pract conf "Actual issues of pathology under the conditions of action of extraordinary factors on the body". Galician readings II (Ternopil’, October 29-30, 2020). Ternopil’; 2020: 119-120. Babelyuk VY, Babelyuk NV, Popovych IL, Gozhenko AI, Kyrylenko IG, Korolyshyn TA, Dubkova GI, Kovbasnyuk MM, Hubyts’kyi VY, Kikhtan VV, Musiyenko VY, Dobrovolsky YG, Korsunskyi IH, Zukow W. Adaptogenic effects of transcutaneous electrical stimulation with the device “VEB” ®. In: Mater of the XIII All-Ukrainian Scie-Pract conf. "Actual issues of pathology under the conditions of action of extraordinary factors on the body". Galician readings II (Ternopil’, October 26-28, 2020). Ternopil’; 2022: 78-78. Babelyuk VY, Dobrovolsky YyG, Popovych IL, Korsunskiy IG. Generator for electrotherapy and stimulation oh human nerve centers [in Russian]. Tekhnologiya i Konstruirovaniye v Elektronnoy Apparature. 2017; 1-2: 23-27. Babelyuk VY, Dubkova HI, Korolyshyn TA, Mysula IR, Popovych DV, Popovych IL, Zukow W. Relationships between caused by Kozyavkin© method changes in parameters of manual function and electroencephalogram, heart rate variability as well as gas discharge visualization in children with spastic form of cerebral palsy. Journal of Education, Health and Sport. 2018; 8(4): 159-194. Babelyuk VY, Gozhenko AI, Dubkova GI, Babelyuk NV, Zukow W, Kindzer BM, Kovbasnyuk MM, Popovych IL. Causal relationships between the parameters of gas discharge visualization and phagocytosis. Journal of Education, Health and Sport. 2021; 11(6): 268-276. Babelyuk VY, Tserkovniuk RG, Babelyuk NV, Żukow X, Ruzhylo SV, Dubkova GI, Korolyshyn TA, Hubyts’kyi VY, Kikhtan VV, Gozhenko AI, Popovych IL. The parameters of gas discharge visualization (biophotonics) correlated with parameters of acupuncture points, EEG, HRV and hormones. Journal of Education, Health and Sport. 2021; 11(12): 359-373. Babelyuk VY, Tserkovniuk RG, Dubkova GI, Korolyshyn TA, Hubyts’kyi VY, Kikhtan VV, Gozhenko AI, Popovych IL. Parameters of gas discharge visualization (biophotonics) correlated with parameters of acupuncture points, EEG, HRV and hormones. In: Mater of the XIII All-Ukrainian Scie-Pract conf. "Actual issues of pathology

    Features of metabolic reactions to various water-salt loads in female rats

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    Background. In the previous article we reported that screening registered parameters of water-salt, nitrous and lipid metabolism as well as the neuroendocrine-immune complex found 42 among them who in rats subjected to various water-salt loads, significantly different from that of intact rats, but on average the same group of animals that received liquids with different mineralization and chemical composition. The purpose of this article is to find out the features of the reactions of the parameters of metabolism. Materials and methods. Experiment was performed on 58 healthy female Wistar rats 240-290 g divided into 6 groups. Animals of the first group remained intact, using tap water from drinking ad libitum. Instead, the other rats received the same tap water as well as waters Sophiya, Naftussya, Gertsa and its artificial salt analogue through the probe at a dose of 1,5 mL/100 g of body mass for 6 days. The day after the completion of the drinking course in all rats the parameters of water-salt, nitrous and lipid metabolism were registered. Results. Found that 16 metabolic parameters the maximum deviates from the level of intact rats under the influence of the salt analogue of Gertsa water, a smaller, but tangible effect is made by the Gertsa native water, even less effective waters Sofiya and Naftussya, instead of ordinary water is almost ineffective in relation to these metabolic parameters. The other 19 parameters deviates to a maximum extent from the reference level after the use of water Naftussya, fresh water is less effective, whereas quasi-isotonic liquids are practically inactive for these parameters. The remaining 13 parameters in animals that use normal water, deviates from intact control to the same extent as in the previous pattern, which, apparently, is also due to the stressful effects of the load course. Both Naftussya and Gertsa water and its salt analogue prevent the stress deviations of these parameters. Instead, by consumption of water Sofiya stresses deviations of these parameters is reversed. The method of discriminant analysis revealed 33 variables (among them 8 refer to plasma/erythrocytes electrolytes, 7 to electrolytes of urine, to other metabolic parameters of plasma 5 and urine 9, as well as glomerular filtration, canalicular reabsorption, diurese and urine osmolarity), the totality of which the metabolic reactions to various water-salt loads are identified (recognized) with an accuracy of 98,3%. Conclusion. The features of the reactions of the parameters of metabolism are due to the content in waters NaCl, SO42- as well as organic carbon and nitrogen
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