486 research outputs found
Evaluation of coronary flow with computed tomography derived FFR: Advantages and pitfalls
No full textCoronary computed tomographic angiography (CCTA) is an excellent noninvasive, anatomic imaging modality for direct visualization of coronary arteries and for the assessment of coronary artery disease (CAD). CCTA has high sensitivity and high negative-predictive value for the identification of obstructive CAD; however, its specificity and positive-predictive value are low. After more than a decade of using CCTA to assess the anatomic severity of CAD, novel modalities of obtaining functional information from CCTA have been developed to increase its specificity and accuracy. These modalities use computational fluid dynamics to calculate fractional flow reserve (FFR) from CCTA datasets. Computed tomography-derived FFR (FFRCT) predicts virtual hyperemia for computation. Therefore, no additional image acquisition, medication, radiation exposure, or pharmacologic stress agent during CCTA examination are necessary for the calculation of FFRCT. Multiple, prospective single or multicenter studies have shown that FFRCT is poised to become a gate-keeper for catheterization laboratory. In this article, we aim to review the principles, diagnostic accuracy, advantages, limitations, and pitfalls of FFRCT
Thickness of carotid intima and epicardial fat in rosacea: a cross-sectional study
No full textAbstract: Background: Rosacea is a chronic facial skin disease associated with excessive inflammatory response to various triggers. Although some studies have supported the increased risk of cardiovascular diseases in rosacea, it has not been completely accepted. Objective: We aimed to investigate epicardial fat thickness and carotid intima-media thickness as cardiovascular risk predictors in rosacea patients. Methods: We conducted a cross-sectional study including 40 rosacea patients and 40 controls. Demographic data, epicardial fat thickness, carotid intima-media thickness, lipid parameters, biochemical parameters, presence of insulin resistance, and presence of metabolic syndrome of the participants were recorded. Results: Forty rosacea patients (31 female and 9 male) and 40 controls (30 female and 10 male) were enrolled in the study. Rosacea patients had significantly higher epicardial fat thickness and carotid intima-media thickness volumes than controls (P<0.001). In the multivariate logistic regression analysis, epicardial fat thickness was independently related to presence of rosacea (P<0.001, OR=13.31). In the multiple linear regression analysis, the epicardial fat thickness was independently associated with rosacea (β= 0.47, P<0.001), carotid intima-media thickness (β= 0.36, P<0.001), and systolic blood pressure (β=0.19, P=0.015) and the carotid intima-media thickness was independently associated with epicardial fat thickness (β= 0.6, P<0.001). The epicardial fat thickness levels were correlated with carotid intima-media thickness (r=0.63, P<0.001), LDL (r=0.23, P=0.037), systolic blood pressure (r=0.45, P<0.001), and diastolic blood pressure levels (r=0.37, P=0.001). The carotid intima-media thickness levels were correlated with epicardial fat thickness (r=0.63, P<0.001), systolic blood pressure (r=0.04, P<0.001), and diastolic blood pressure levels (r=0.27, P=0.016). Study limitations: The small number of participants. Conclusions: Examination and follow-up of rosacea patients for cardiovascular diseases may be recommended practices
SOCIO-ECONOMIC IMPACT OF SUPPORT TURKISH NGOs ON DEVELOPING COUNTRIES: SADAKATASI ASSOCIATION
No full textMakale, İbrahim Güran Yumuşak’ın danışmanlığında Hacı Altun tarafından hazırlanan “Türkiye’deki Sivil Toplum Kuruluşlarının Az Gelişmiş Ülkelere Sosyo-Ekonomik Katkıları: Sadakataşı Derneği Örneği” başlıklı yüksek lisans projesine dayalı olarak hazırlanmış ve güncellenmiştir. -- Prof. Dr. İstanbul S. Zaim Üniversitesi, [email protected] -- Sadakataşı Derneği, İstanbul, [email protected]ünümüzde Sivil Toplum Kuruluşları gün geçtikçe önemi artan ve etki alanı genişleyen bir işleve sahip
olmaktadır. STK’larının güçlenmesi ve büyümesi, devletin üzerinden sosyal sorumluluk kapsamındaki yükleri
azaltmaktadır. STK’ların bir bölümü sadece kendi ülkesi sınırları içerisinde değil diğer ülkelere yönelik
faaliyetlerde bulunmaktadırlar. Son on yılda Türkiye’de, başta Osmanlı hinterlandında bulunan ülkeler olmak
üzere birçok az gelişmiş ülke ve bölgelere yönelik faaliyetler gerçekleştiren STK’ların sayısı oldukça artmıştır.
Makalede, Türkiye sınırları dışında faaliyet gösteren STK’lardan biri olan Sadakataşı Derneği’nin az gelişmiş ülke
ve bölgelere yönelik yaptığı faaliyetler analiz edilerek sosyo-ekonomik katkıları incelenmektedir. Az gelişmiş
ülkelere yapılan eğitim, sağlık ve gıda yardımları, ülkenin beşeri sermaye potansiyelini geliştirmekte ve iktisadi
hayatı canlandırmaktadır. Bunun yanısıra kabullenilmiş fakirlik algısının kırılmasına ve Türk halkıyla bölge insanı
arasında dostluk bağlarının güçlenmesine önemli katkılar sağlamaktadır.Today, Civil Society Organizations (NGOs) have an increasingly important and expanding role. Strengthening
and growing NGOs reduces the burden of the state concerning social responsibility. Some of the NGOs are
engaged not only in their own borders but also in other countries. Over the past decade, the number of NGOs in
Turkey, especially those active in the hinterlands of the Ottoman Empire, has been increasing. In this article, the
socio-economic contributions of the Sadakataşı Association, one of the NGOs operating outside the borders of
Turkey, are analyzed by examining the activities of the association for the less developed countries and regions.
Education, health and food aids made to underdeveloped countries improve the human capital potential of the
country and stimulate the economic life. Besides, it contributes to breaking the accepted perception of poverty and
strengthening the bonds of friendship between the Turkish people and the people of the region
Associations of non-HDL-C and triglyceride/HDL-C ratio with coronary plaque burden and plaque characteristics in young adults
No full textCoronary artery disease (CAD) is uncommon in young adult patients. However, these patients have different risk factor profiles and high-risk coronary plaques are more common. The aim of this study was to examine the relations between the coronary plaque burden, plaque composition, serum non-high-density lipoprotein cholesterol (non–HDL-C) levels, and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio in young adults. We analyzed a total of 551 patients under age 45 who had undergone coronary computed tomography angiography (CCTA). Coronary plaque characteristics were analyzed using CCTA. Multivariate linear regression analysis was used to assess the predictors of non-calcified plaque (NCB) and calcified plaque (CB) burdens. Serum non–HDL-C levels and TG/HDL-C ratio were higher in the coronary atherosclerosis patient group. Serum non–HDL-C levels and the TG/HDL-C ratio were higher in the obstructive CAD patient group. The plaque burden was positively correlated with non-HDL-C (r = 0.30; p < 0.001), and TG/HDL-C ratio (r = 0.18; p < 0.001). NCB was positively correlated with age, gender, smoking status, fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, serum triglycerides, hbA1c, non–HDL-C, and TG/HDL-C ratio. Non–HDL-C (β coefficient = 0.13; p = 0.023) and TG/HDL-C ratio (β = 0.10; p = 0.042) were independent predictors of NCB. Serum non–HDL-C levels and TG/HDL-C were significantly associated with the presence and burden of coronary plaques. Serum non–HDL-C and TG/HDL-C ratios were independently associated with NCB, suggesting their use as easy-to-compute markers for identifying high-risk groups in young adults
Peripartum cardiomyopathy and triplet pregnancy [Letter]
No full textPubMed ID: 25550262[No abstract available
Effect of COPD on cognitive functions in patients with heart failure
No full textWOS: 000354008100015PubMed ID: 2572411
A Rare Congenital Cardiac Anomaly Presenting with Amaurosis Fugax: Quadricuspid Aortic Valve
No full textQuadricuspid aortic valve (QAV) is a rare cause of aortic regurgitation. Most cases are detected incidentally during echocardiography, angiography, autopsy or surgery. It may also be associated with other congenital anomalies of the heart. A 27-year-old male was admitted to our department to evaluate the etiology of amaurosis fugax. On physical examination, his blood pressure was 125/85 mmHg, and an evident diastolic murmur of grade 2/6 was heard at the third left intercostal space. Results of electrocardiography and chest radiography were normal. Transthoracic and transoesophageal echocardiography revealed a quadricuspid aortic valve, a mild aortic regurgitation. The importance of recognizing this condition lies in the fact that more than 50% of people with QAV require valve replacement in the fifth or sixth decade of life, because of worsening aortic regurgitation
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