112,965 research outputs found
Integrated assessment of energy performance and seismic vulnerability of existing building stock at urban scale through BIM: an application to “Fiera del Levante”
No full textThe paper presents a research work concerned with the integrate assessment of seismic vulnerability and energy performance of existing buildings at urban scale through BIM (Building Information Modelling). At the urban scale, it is often required to manage large set of buildings, for which it is not possible to perform detailed investigation, modeling and analysis.At this scale of analysis, an additional issue is the coexistence of different building components and performance requirements (structural safety, functional and aesthetic efficiency, energy efficiency, and so on), which often have a dynamic interaction.For this reason, the modeling approach should be able to encounter this complexity and provide the interaction of multiple expertise, in order to provide optimal solutions of the critical issues and vulnerability of buildings.Within this context, the research has proposed and tested a framework structured through a suitable BIM model finalized to implementation of integrated simplified evaluation procedure of seismic vulnerability and energy performance at urban scale.The objective is to provide an innovative tool for the performance-based assessment in a context of uncertainty and incomplete information typical of the urban scale analysis.The proposed approach allows to manage information from different source and quick investigations concerns structural safety and energy efficiency, and it has been focused on the case study of "Fiera del Levante", a trade fair district extending over 280.000 m(2), composed by several buildings aged from 1929 to 2012, that host about thirty events (including international fair shows) throughout the year as well as conferences and/or exhibitions
Reduced access to primary care for immigrants increases cardiovascular complications and hospital admissions. The importance of information and education
No full textSi dimostra l'importanza di una appropriata educazione ed informazione per quanto riguarda come accedere al Sistema Sanitario Nazionale Italiano per le persone provenienti da paesi stranier
author-bios-SRD-19-0063.R1 – Supplemental material for The Network Structure of Police Misconduct
No full textSupplemental material, author-bios-SRD-19-0063.R1 for The Network Structure of Police Misconduct by George Wood, Daria Roithmayr and Andrew V. Papachristos in Socius</p
Le condizioni soggettive di ricevibillità del rinvio pregiudiziale
No full textLa nozione di giurisdizione ai fine dell'applicazione del rinvio pregiudiziale alla Corte di giustizi
Anima: un rompicapo per le scienze sociali? Il contributo di Pareto
No full textÈ noto che per Pareto la scienza non è una pura e semplice riproduzione dei fenomeni che osserviamo esteriormente (Pareto non è un mero “positivista”) e che non deve occuparsi tanto delle azioni logico-sperimentali, ma soprattutto di quelle non logiche, essendo esse la maggioranza, quelle meno conosciute, quelle più dissimulate e sfigurate (perché forte, come sappiamo, è la tendenza degli esseri umani ad ingannarsi, vittime come sono dell'istinto umano alle razionalizzazioni). È vero, dunque, che la scienza (con il suo metodo, il suo oggetto e la sua tensione ideale) deve essere logico-sperimentale, ma questo non significa chiudere gli occhi di fronte a ciò che logico e sperimentale non è. Anzi. Tutto lo sforzo del Trattato di sociologia generale (V. Pareto, 1916, 1964), come noto, consiste semmai, nel capire e spiegare, in maniera logica e scientifica tutta quella infrastruttura di sentimenti, istinti, impulsi e creatività (D. Padua, 2009) che è alla base delle azioni non logiche. È questo il problema fondamentale affrontato nell’opera, lo snodo principale dei suoi studi, ma è anche, a mio avviso, ciò che più può aiutare a spiegare scientificamente il concetto di anima (e ciò al di là di quanto Pareto abbia o meno utilizzato espressamente questa categoria concettuale nelle sue opere). In che senso, dunque, la sociologia di Pareto può contribuire a spiegare scientificamente il concetto di anima? E qual è il vantaggio di questa operazione? A che serve dire che la sociologia di Pareto aiuti nella spiegazione del concetto di anima
Phenotyping of chondrocytes from human osteoarthritic cartilage: chondrocyte expression of beta integrins and correlation with anatomic injury
No full textChondrocyte-ECM (extracellular matrix) interactions are believed to play a pivotal role in the development and metabolic homeostasis of articular cartilage. Cell surface adhesion molecules have been reported to modulate chondrocyte binding to ECM (collagen, fibronectin, laminin) and they also act as transducers of critical signals in many biological processes such as growth, differentiation, migration and matrix synthesis. Recently, it has been shown that normal human articular chondrocytes strongly express ß1 integrins, which are constituted by a common chain (ß1) and a variable α chain, but the behaviour of these molecules in human osteoarthritic cartilage has not been extensively investigated. We studied the expression of ß integrins (ß1-5, α1-6, av chains), LFA-1, ICAM-1 and CD44, on freshly isolated chondrocytes obtained from 10 osteoarthritic patients undergoing surgical knee replacement. Chondrocytes were isolated by enzymatic digestion from three zones of each articular cartilage with a differing degree of macroscopic and microscopic damage. Integrin expression and cell cycle analysis were carried out by flowcytometry. Chondrocytes from costal cartilages of 5 human fetuses were also studied. Chondrocytes from osteoarthritic cartilage expressed high levels of ß1 integrin and, at different percantages, all the α chains. The α chain most frequentiy expressed was α1, foilowed by α3, α5, α2, αv. Integrin expression decreased from the least to the most damaged zone of articular cartilage and cell cycle analysis showed that proliferating chondrocytes (S phase) were prevalent on the latter zone. ß2, ß3, ß2, ß5, CD44, LFA-1/ICAM-1 complex were very low expressed. Fetal chondrocytes strongly expressed ß1 and ß5 chains. These data provide evidence to show that integrin expression on human chondrocytes changes in osteoarthritis and suggest that perturbations of chondrocyte-ECM signalling occur in the development of the disease. The different pattern of expression of ß1 and ß5 chains on adult and fetal chondrocytes leads to speculate that integrins play a key role in control of cartilage morphogenesis and differentiation
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
FRAGSTATS: A Free Tool for Quantifying and Evaluating Spatial Patterns
No full textHuman activities such as urbanization and agriculture have triggered rapid land cover change, resulting in the loss of natural ecosystems. Land managers managers seeking to plan effectively for future land use that preserves biodiversity and the valuable services provided by natural ecosystems must understand land cover change and its environmental impacts. Quantifying patterns of land cover change objectively in order to understand them can be difficult without the proper resources, however. This 9-page fact sheet written by Benxin Chen and Basil V. Iannone III and published by the UF/IFAS School of Forest Resources and Conservation introduces one such resource, a free software called FRAGSTATS. Readers will learn to create input data, run the FRAGSTATS software, and interpret outputs. A few basic concepts of landscape ecology and GIS are included, but this fact sheet is intended for readers with at least some GIS knowledge
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