102,273 research outputs found
Preface
No full textThis Special Issue is dedicated to the memory of Klaus
Muller.
This Special Issue focuses on Sol–Gel R&D in Italy,
with the purpose of giving a short overview of current
research trends in this field and presenting the main laboratories
working on sol–gel. The Italian community,
though it has a small number of researchers, has been one
of the most active in sol–gel research from the very
beginning.
The first International Sol–Gel Workshop of the series
was held in Padova, with several laboratories playing a
pivotal role in basic sol–gel research, which has been
widely recognized worldwide. This Issue also has the
purpose of increasing international collaborations along
with information on those who work in this field, and
hopefully should be the first of a series of Special Issues
dedicated to different countries. We would like to thank all
the contributors to this special Issue and in particular to the
Editor-in-Chief of the Journal of Sol–Gel Science and
Technology, Michel Aegerter, for his precious support.
We have dedicated this Special Issue to Prof. Klaus
Muller from the University of Trento who suddenly passed
away during the preparation of the Issue; it is an enormous
loss for our community and his family.
The Special Issue Editors
Plinio Innocenzi, Giovanna Brusatin, Antonio Aronne,
Sandra Dire`, Franca Morazzon
Prolonged stabilization of multiple and single brain metastases from breast cancer with tamoxifen. Report of three cases
No full textCancer frequently metastasizes to the brain, and such lesions, whether multiple or solitary, have a poor prognosis, despite all efforts to treat them. There have been recent sporadic reports of brain metastases from breast cancer responding for some years to antiestrogens (particularly tamoxifen) or bromocryptine. We report three cases of brain metastasis from cancer - two multiple and one a solitary lesion. The long survival of the patients - two for 5 years and one for 6 years, with more than an acceptable quality of life - should prompt therapeutic trials to test tamoxifen and designed to assess its effects on a sizable number of patients
A new topical salicylic acid in a thermoactivable foam for mild acne treatment. Results of a pilot trial
No full text
Top-down patterning of Zeolitic Imidazolate Framework composite thin films by deep X-ray lithography
No full textFor the first time a top-down process was used to control the spatial location of Metal–Organic Frameworks on a surface. Deep X-ray lithography was utilised to micropattern a Zeolitic Imidazolate Framework layer on a sol–gel surface, with exposure hardening the sol–gel by inducing crosslinking while leaving the frameworks intact.Constantinos Dimitrakakis, Benedetta Marmiroli, Heinz Amenitsch, Luca Malfatti, Plinio Innocenzi, Gianluca Grenci, Lisa Vaccari, Anita J. Hill, Bradley P. Ladewig, Matthew R. Hill, Paolo Falcar
HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET) IS INVOLVED IN EMBRYONIC MOUSE TESTIS DEVELOPMENT.
No full textAbstractThe hepatocyte growth factor (HGF) receptor, c-met, transduces the HGF multiple biological activities. During embryonic development the system HGF/c-met regulates the morphogenesis of different organs and tissues. In this study we examined c-met gene expression during mouse testis development and, by means of Northern blot and in situ hybridization, we report the receptor expression pattern. C-met expression is not detectable in male genital ridges isolated from embryos at 11.5 days postcoitum (dpc). In testes isolated from 12.5 and 13.5 dpc, c-met expression is detectable and essentially localized in the developing cords. Male genital ducts do not express c-met at the reported ages, whereas female ducts appear c-met positive. Moreover, we report that HGF is able to induce testicular morphogenesis in vitro. Male genital ridges isolated from embryos at 11.5 dpc are morphologically nonorganized. Culturing 11.5 dpc urogenital ridges in the presence of HGF we obtained testis organization and testicular cord formation. Our data demonstrate that c-met is expressed during the beginning period of testis differentiation and that HGF is able to support testicular differentiation in vitro. All these data indicate that this growth factor, besides its role as mitogenic factor, plays a fundamental role during testicular cord formation probably inducing cell migration and/or cell differentiation
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