1,720,984 research outputs found

    A simple method to estimate the episode and programme sensitivity of breast cancer screening programmes

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    Background: The estimation of breast cancer screening sensitivity is a major aim in the quality assessment of screening programmes. The proportional incidence method for the estimation of the sensitivity of breast cancer screening programmes is rarely used to estimate the underlying incidence rates. Methods: We present a method to estimate episode and programme sensitivity of screening programmes, based solely on cancers detected within screening cycles (excluding breast cancer cases at prevalent screening round) and on the number of incident cases in the total target population (steady state). The assumptions, strengths and limitations of the method are discussed. An example of calculation of episode and programme sensitivities is given, on the basis of the data from the IMPACT study, a large observational study of breast cancer screening programmes in Italy. Results: The programme sensitivity from the fifth year of screening onwards ranged between 41% and 48% of the total number of cases in the target population. At steady state episode sensitivity was 0.70, with a trend across age groups, with lowest values in women aged 50-54 years (0.52) and highest in those 65-69 (0.77). Conclusions: The method is a very serviceable tool for estimating sensitivity in service screening programmes, and the results are comparable with those of other methods of estimation.Background: The estimation of breast cancer screening sensitivity is a major aim in the quality assessment of screening programmes. The proportional incidence method for the estimation of the sensitivity of breast cancer screening programmes is rarely used to estimate the underlying incidence rates. Methods: We present a method to estimate episode and programme sensitivity of screening programmes, based solely on cancers detected within screening cycles (excluding breast cancer cases at prevalent screening round) and on the number of incident cases in the total target population (steady state). The assumptions, strengths and limitations of the method are discussed. An example of calculation of episode and programme sensitivities is given, on the basis of the data from the IMPACT study, a large observational study of breast cancer screening programmes in Italy. Results: The programme sensitivity from the fifth year of screening onwards ranged between 41% and 48% of the total number of cases in the target population. At steady state episode sensitivity was 0.70, with a trend across age groups, with lowest values in women aged 50-54 years (0.52) and highest in those 65-69 (0.77). Conclusions: The method is a very serviceable tool for estimating sensitivity in service screening programmes, and the results are comparable with those of other methods of estimation

    A simple method to estimate the episode and programme sensitivity of breast cancer screening programmes.

    No full text
    BACKGROUND: The estimation of breast cancer screening sensitivity is a major aim in the quality assessment of screening programmes. The proportional incidence method for the estimation of the sensitivity of breast cancer screening programmes is rarely used to estimate the underlying incidence rates. METHODS: We present a method to estimate episode and programme sensitivity of screening programmes, based solely on cancers detected within screening cycles (excluding breast cancer cases at prevalent screening round) and on the number of incident cases in the total target population (steady state). The assumptions, strengths and limitations of the method are discussed. An example of calculation of episode and programme sensitivities is given, on the basis of the data from the IMPACT study, a large observational study of breast cancer screening programmes in Italy. RESULTS: The programme sensitivity from the fifth year of screening onwards ranged between 41% and 48% of the total number of cases in the target population. At steady state episode sensitivity was 0.70, with a trend across age groups, with lowest values in women aged 50-54 years (0.52) and highest in those 65-69 (0.77). CONCLUSIONS: The method is a very serviceable tool for estimating sensitivity in service screening programmes, and the results are comparable with those of other methods of estimation

    The Ocean Impact Navigator. A new impact measurement framework for the ocean innovation ecosystem.

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    Creating positive impact for the ocean has never been more urgent. Measuring this impact, however, remains a critical challenge. To support innovators, their investors, and backers in charting these turbulent waters, this report presents the Ocean Impact Navigator, a new KPI impact framework for the Ocean Innovation Ecosystem. Ocean health is in peril. Multiple compounding stressors, including habitat destruction, overfishing, invasive species, pollution, and climate change, pose an existential threat to marine ecosystems and the crucial services they provide. These stressors and their cascading systemic impacts, combined with historic underinvestment in regenerative and nature-positive ocean sectors, are ushering in grave consequences for the 3 billion people worldwide who consume nutritious blue food, for coastal communities at risk of flooding, and for all those whose livelihoods and well-being relies on the ocean. Despite this bleak outlook, hope remains. The ocean holds astonishing potential for regeneration and, crucially, offers solutions that can address not only the threats it faces, but also the world’s broader climatic, biodiversity and social challenges. Capitalising on this potential, new start-ups and innovators are emerging, offering solutions to regenerate ocean health and catalyse the transition to a Sustainable Ocean Economy that unites effective ocean protection, sustainable production, and equitable prosperity. These innovations span a range of interrelated sectors – across food production, energy, biotech, data, transport, tourism, and solutions to pollution – that can drive systemic transformation in the blue economy. In parallel, new private and public capital is being mobilised for investment in the ocean, and incubators, accelerators, competitions, and matching platforms provide innovators with crucial backing and support. Together, these players make up the Ocean Impact Innovation (OII) ecosystem, largely encompassed by the 1000 Ocean Startups coalitionChallenges 5, 10PublishedReferee

    The Ocean Impact Navigator. A new impact measurement framework for the ocean innovation ecosystem. Technical Appendix. Work in Progress.

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    This Technical Appendix has been written as a companion to the Ocean Impact Navigator: A New Impact Measurement Framework for the Ocean Innovation Ecosystem. It provides further details on the KPIs proposed within the Navigator framework. At the time of publication in June 2022, the Navigator has not yet been finalised, but is embarking on a period of testing, feedback and refinement that is expected to culminate in the launch of an online tool at the end of the year. It is in this spirit of soliciting feedback from the ocean impact and innovation community that this Appendix is published, as we hope that it will enable interested members of the community to review and provide more nuanced and detailed comments on the proposed framework. It is expected both that the set of KPIs elaborated in this Appendix will be revised in the coming months, and that the detailed guidance outlined in this Appendix will also be refined, based on the feedback that is received. It is also hoped that Navigator users – both now and in the future, will find this a practical tool to support implementation of the framework for their own impact measurement.Challennge 5, 10PublishedReferee

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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