1,720,964 research outputs found
Muscle elastography: a new imaging technique for multiple sclerosis spasticity measurement
No full textMultiple sclerosis (MS) spasticity is currently evaluated on the basis of neurological examinations such as Ashworth Scale (AS) and 0–10 NRS. Severity of spasticity is difficult to quantify. We investigated the use of real time elastography (RTHE) ultrasounds for evaluating objectively the muscle fibers status in MS spasticity patients and their changes after a new antispasticity treatment. Two studies were performed. In study A, 110 MS patients underwent a neurological evaluation based on the AS and RTHE. The RTHE images were scored with the new 1-5 muscle fibers rigidity imaging scale, here called MEMSs (Muscle Elastography Multiple Sclerosis Score). The correlation between AS and MEMSs was found to be statistically significant. In study B, 55 MS patients treated with THC:CBD oromucosal spray for their resistant spasticity were followed prospectively. MS spasticity was evaluated by the 0–10 NRS scale at baseline and after 4 weeks of treatment. MEMSs’ figures were obtained at both timepoints. Responders to THC:CBD oromucosal spray (pre-defined as an improvement ≥20% in their 0–10 NRS spasticity score vs. baseline) were 65% of sample. These patients had a mean 0-10 NRS reduction of 1.87 and a MEMSs reduction of 1.97 (P values <0.0001). The remaining 35% of patients, classified as clinically non-responders, showed still a significant mean reduction in MEMSs (0.8, P = 0.002). Our overall results showed that RTHE, operativized throughout MEMSs, could be an objective gold standard to evaluate MS muscle spasticity as well as the effectiveness of antispasticity therapy
THE CONTRIBUTION OF PREOPERATIVE ULTRASONOGRAPHY IN THE SURGICAL TREATMENT OF HEPATIC HYDATID DISEASE
No full textPROPOSED RAT MODEL FOR THE EVALUATION OF THE INFLUENCE OF HP VARIATIONS ON HELICOBACTER PYLORI VIRULENCE
No full textPREVALENCE OF GASTROESOPHAGEAL REFLUX DISEAS IN HELICOBACTER PYLORI-POSITIVE PEPTIC ULCER DISEAS AND SHORT TERM EFFECTS OF ERADICATION TERAPHY
No full text
Ricerca di Yersinia pseudotuberculosis negli ovi-caprini come potenziali diffusori nell'ambiente; valutazione dei determinanti di patogenicità dei ceppi presenti nel territorio della Sardegna e loro eventuale ruolo patogenetico nell'uomo
No full textAl genere Yersinia appartengono diverse specie batteriche
ampiamente diffuse in natura, alcune delle quali come la
stessa Yersinia pseudotuberculosis sono ritenute
responsabili di patologie animali (specialmente nei roditori)
e umane [1]. Nell’uomo, infatti, tale microrganismo è coinvolto in
casi di appendicite e linfadenite mesenterica, diarrea e setticemia
[2, 3]; in diverse specie animali può essere responsabile di affezioni
enteriche ed essere isolato in casi di placentite con aborto e mastite
nelle pecore [4-6]. Anche gli animali selvatici e in particolare gli
uccelli sono considerati riserve importanti del germe. La
contaminazione del suolo e delle acque contribuisce alla trasmissione
all’uomo e ciò suggerisce interazioni tra ospiti e ambiente.
L’isolamento di Yersinia pseudotuberculosis nel corso di indagini
batteriologiche, condotte a scopo diagnostico nei laboratori
dell’Istituto zooprofilattico sperimentale della Sardegna, su latte e
feti ovini e caprini, ha suggerito di verificare il ruolo di queste specie
animali quali diffusori di Y. pseudotuberculosis nell’ambiente e
quindi all’uomo. Aquesto proposito si è inteso valutare la presenza
del microrganismo anche in soggetti umani interessati da alcune
patologie enteriche
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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