1,720,966 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Iodinated contrast media in diagnostic imaging: Cardiovascular side effects
No full textBackground: Cardiovascular side effects occur rarely after iodinated contrast media administration and no real data can be found in literature. The presence of cardiovascular risk factors increases the incidence of these adverse reactions. Objective: Aim of the study was the analysis of the cardiovascular side effects due to use of intra-venous iodinated contrast media in diagnostic imaging. Methods: A MEDLINE and Pubmed research was performed for journals with MeSH major terms âiodinated contrast mediaâ and âcardiovascular side effectsâ. Non-English speaking literature was excluded. Results: Intravenous iodine contrast agents could be determined with low frequency cardiovascular side effects, such as arrhythmias, related to increased levels of thyroid hormones. Indeed after the contrast media administration, in euthyroid patients the iodine stores remain elevated up to two months. Instead the vasomotor reactions (orthostatic hypotension and reflex tachycardia) and /or vasovagal response (syncope and bradycardia) are the most frequent. Conclusion: The rarity and the mild-moderate type of the cardiovascular side effects do not justify the electrocardiogram test as a preliminary exam for iodine contrast media usage. Emergency medical team should be alert in case of need. Atropine is the first choice in the hypotensive crisis due to contrast agents
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Drug safety warnings in psychiatry: Adverse drug reactions' signaling from 2002 to 2014
Full text linkObjective. Monitoring drug-related side effects in psychiatric patients is highly recommended. In fact, frequent exposure to long-term polipharmacotherapy, poor compliance to pharmachological treatment and comorbidity with organic illnesses requiring the prescription of other drugs are causes of pharmacokinetic/pharmacodynamic interactions. These vulnerability factors result in a certain increase in adverse drug reactions (ADRs). Methods. This study performes an analysis of Italian Medicine Agency data, in the section "signal analysis", to attempt an assessment of the safety warnings among the different psychotropic drug classes, belonging to the ATC class: N03 (antiepileptics), N05 (antipsychotics), N06 (psycho-analectic drugs). Then we analysed, in a descriptive way, the different association between the drug and the related ADR, evaluating the different safety profiles, in relation to experimental studies, supporting the importance of the signal. Results. In the last years, among the new 25 ADRs, 10 were related to antidepressant drugs (8 SSRI, 1 mirtazapine, 1 agomelatine). In relation to antipsychotic drugs, 6 new correlations were found between drug and ADR onset, mainly among atypical antispychotics. Other correlations (6 above all) were found among antiepileptic drugs. Among benzodiazepines, a signal linked to rabdomylysis onset was found. It is also recommended an evaluation of safety profile in relation to zolpidem prescription. Discussion. The results of our systematic review are a motivational input, considering the continuous increase of safety warnings, to attentively monitor drug's prescription. Spontaneous ADRs' signaling is a classical system to provide the required attention in relation to a potential risk. The clinician in charge must report this because he is the key figure in the drugs' safety process. Conclusions. In psychiatry, in which a long-term pharmachological therapy is frequent, clinicians are requested to find and signal ADRs to the competent authority
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Combined job's syndrome and klinefelter syndrome: A case report
No full textTo date, there are no case reports on combined Job's Syndrome (JS) and Klinefelter syndrome (KS). We describe the case of a 36-year-old man with KS and hyper-IgE Syndrome, detected at genetic tests. The patient, with testicular volume reduction, ginecomastia and hepatic steatosis underwent hormone replacement therapy with testosterone enanthate to increase testosterone blood levels, despite the side effects of the treatment and antibiotic prophylaxis against lung infections. This is the first case report of combined JS and KS diagnosed in young man, and it indicates the need to consider the concurrent existence of these two disorders in patients with recurrent lung infections, subcutaneous abscesses and IgE increase
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