2,532 research outputs found

    [Letter from Mr. Takashima to Mr. M. Okada]

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    Correspondence from Misao Okada's scrapbook. Summary in English: In this letter, Mr. Takashima mentions that there are possible jobs in Visalia that pay $200/month.Misao Okada’s scrapbook contains photographs, ephemera, notes, and correspondence documenting her time at Amache and a visit and reunion over 50 years later. The scrapbook also includes materials relating to reparations and events observing Japanese American incarceration

    Lithobius (Ezembius) irregularis Takakuwa & Takashima 1949

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    <i>Lithobius</i> (<i>Ezembius</i>) <i>irregularis</i> Takakuwa & Takashima, 1949 <p> <i>Lithobius irregularis</i> Takakuwa & Takashima, 1949: 61, figs 11 <b>–</b> 13 <i>Lithobius irregularis</i> <b>—</b> Wang & Mauriès, 1996: 90</p> <p> <i>Lithobius</i> (<i>Ezembius</i>) <i>irregularis</i> <b>—</b> Zapparoli, 2006</p> <p> <b>Previous records.</b> Shanxi Province (Xinzhou City) (Takakuwa & Takashima, 1949).</p> <p> <b>Remarks.</b> Only known from China. Takakuwa and Takashima’s original description of this species was based on only two female specimens from Shanxi Province. Zapparoli (2006) placed <i>irregularis</i> in <i>Lithobius</i> (<i>Ezembius</i>).</p>Published as part of <i>Ma, Huiqin, Pei, Sujian, Hou, Xiaojie, Zhu, Tiegang, Wu, Dayong & Gai, Yonghua, 2014, An annotated checklist of Lithobiomorpha of China, pp. 333-358 in Zootaxa 3847 (3)</i> on page 342, DOI: 10.11646/zootaxa.3847.3.2, <a href="http://zenodo.org/record/231285">http://zenodo.org/record/231285</a&gt

    Lithobius (Ezembius) sulcifemoralis Takakuwa & Takashima 1949

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    Lithobius (Ezembius) sulcifemoralis Takakuwa & Takashima, 1949 Lithobius sulcifemoralis Takakuwa & Takashima, 1949: 60, figs I 7 – 8 Lithobius sulcifemoralis — Wang & Mauriès, 1996: 90 Lithobius (Ezembius) sulcifemoralis — Zapparoli, 2006 Previous records. Shanxi Province (Xinzhou City) (Takakuwa & Takashima, 1949). Remarks. Only known from China. Zapparoli (2006) placed sulcifemoralis in Lithobius (Ezembius).Published as part of Ma, Huiqin, Pei, Sujian, Hou, Xiaojie, Zhu, Tiegang, Wu, Dayong & Gai, Yonghua, 2014, An annotated checklist of Lithobiomorpha of China, pp. 333-358 in Zootaxa 3847 (3) on page 343, DOI: 10.11646/zootaxa.3847.3.2, http://zenodo.org/record/23128

    Bothropolys shanxiensis Takakuwa & Takashima 1949

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    <i>Bothropolys shanxiensis</i> Takakuwa & Takashima, 1949 <p> <i>Bothropolys Shanxiensis</i> Takakuwa & Takashima, 1949: 59; Wang Mauris, 1996: 91; Zapparoli, 2006.</p> <p> <b> <i>Diagnosis</i>:</b> Body length 15.7–25.7 mm, antennae composed of 20+20 antennomeres; 21–28 ocelli on each side; Tömösváry’s organ almost rounded, moderately smaller than the adjoining ocelli; 6+6–9+9 blunt prosternal teeth, usually 7+7; porodonts feebly slender and long, between the second and third outer teeth; posterior angles of T 4 bluntly triangular, posterior angles of TT 6, 7, 9, 11 and 13 sharply triangular; pretarsus of all legs with claws; moderately long accessory claws on both anterior and posterior side of legs 1–13, no accessory claws on legs 14 and 15; female gonopods with 2+2 coniform spurs and tridentate claws. Male gonopods short and small, as a mastoid protuberance, with 6–9 long setae, distally slightly sclerotised.</p> <p> <b>Material examined.</b> 11 ΨΨ, 6 ɗɗ, Xiaowutai National Natural Reserve, Yu County, Zhangjiakou City, Hebei Province, 39°54'N 115°00'E, 20 August 2005, leg. Zhi-sheng Zhang, Zi-zhong Yang, Hui-Qin Ma. 1 Ψ, 3 ɗɗ, Xiaowutai National Natural Reserve, Yu County, Zhangjiakou City, Hebei Province, 39°54'N 115°00'E, 20 July 2002, leg. Ming-sheng Zhu, Zhi-shun Song.</p> <p> <b>Distribution:</b> China (Shaanxi, Hebei).</p> <p> <b>Remarks:</b> Although not collected from type locality, the present specimens with 6+6–9+9 blunt prosternal teeth, usually 7+7; porodonts between the second and third outer teeth; posterior angles of TT 6, 7, 9, 11 and 13 sharply triangular; female gonopods with 2+2 coniform spurs, agree exactly with Takakuwa and Takashima’s brief original description of <i>B. shanxiensis</i>.</p>Published as part of <i>Ma, Hui-Qin, Song, Da-Xiang & Zhu, Ming-Sheng, 2008, A review of the Chinese species of Bothropolys Wood, 1862 (Chilopoda: Lithobiomorpha: Lithobiidae), pp. 35-47 in Zootaxa 1786</i> on pages 44-45, DOI: <a href="http://zenodo.org/record/182487">10.5281/zenodo.182487</a&gt

    Magic moments: On the neural mechanisms of novel word consolidation and integration

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    Contains fulltext : 145492.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 03 december 2015Promotores : McQueen, J.M., Hell, J.G. van Co-promotores : Takashima, A., Janzen, G.209 p

    Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD)

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    Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing. The murine epidermal-derived DC line Xs52, when pulsed with PPD, optimally activated the PPD-reactive Th1 clone LNC.2F1 as well as the Th2 clone LNC.4k1, and this activation was completely blocked by chloroquine pretreatment. These results validate the capacity of XS52 DC to digest PPD into immunogenic peptides inducing antigen specific T cell immune responses. XS52 DC, as well as splenic DC and DCs derived from bone marrow degraded standard substrates for cathepsins B, C, D/E, H, J, and L, tryptase, and chymases, indicating that DC express a variety of protease activities. Treatment of XS52 DC with pepstatin A, an inhibitor of aspartic acid proteases, completely abrogated their capacity to present native PPD, but not trypsin-digested PPD fragments to Th1 and Th2 cell clones. Pepstatin A also inhibited cathepsin D/E activity selectively among the XS52 DC-associated protease activities. On the other hand, inhibitors of serine proteases (dichloroisocoumarin, DCI) or of cystein proteases (E-64) did not impair XS52 DC presentation of PPD, nor did they inhibit cathepsin D/E activity. Finally, all tested DC populations (XS52 DC, splenic DC, and bone marrow-derived DC) constitutively expressed cathepsin D mRNA. These results suggest that DC primarily employ cathepsin D (and perhaps E) to digest PPD into antigenic peptides

    Olfactory input to the parahippocampal region of the isolated guinea pig brain reveals weak entorhinal-to-perirhinal interactions

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    The processing of olfactory inputs by the parahippocampal region has a central role in the organization of memory in mammals. The olfactory input is relayed to the hippocampus via interposed synapses located in the piriform and entorhinal cortices. Whether olfactory afferents directly or indirectly project to other areas of the parahippocampal region beside the entorhinal cortex (EC) is uncertain. We performed an electrophysiological and imaging study of the propagation pattern of the olfactory input carried by the fibres that form the lateral olfactory tract (LOT) into the parahippocampal region of the in vitro isolated guinea pig preparation. Laminar analysis was performed on field potential depth profiles recorded with 16-channel silicon probes at different sites of the insular-parahippocampal cortex. The LOT input induced a large amplitude polysynaptic response in the lateral EC. Following appropriate LOT stimulation, a late response generated by the interposed activation of the hippocampus was observed in the medial EC. LOT stimulation did not induce any local response in area 36 of the perirhinal cortex (PRC), while a small amplitude potential with a delay similar to the lateral EC response was inconsistently observed in PRC area 35. No PRC potentials were observed following the responses evoked by LOT stimulation in either the lateral or the medial EC. These findings were substantiated by current source density analysis of PRC laminar profiles. To further verify the absence of EC-to-PRC field interactions after LOT stimulation, high-resolution optical imaging of neuronal activity was performed after perfusion of the isolated brain with the voltage-sensitive dye RH-795. The optical recordings confirmed that olfactory-induced activity in the EC does not induce massive PRC activation. The present findings suggest that the olfactory input into the parahippocampal region is confined to the entorhinal cortex. The results also imply that, as demonstrated for the PRC-to-EC pathway, the propagation of neuronal activity from the EC to the PRC is hindered, possibly by a powerful inhibitory control generated within the EC

    sj-doc-2-cno-10.1177_2329048X211048613 - Supplemental material for Novel <i>HSD17B4</i> Variants Cause Progressive Leukodystrophy in Childhood: Case Report and Literature Review

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    Supplemental material, sj-doc-2-cno-10.1177_2329048X211048613 for Novel HSD17B4 Variants Cause Progressive Leukodystrophy in Childhood: Case Report and Literature Review by Akiyo Yamamoto, Shinobu Fukumura, Yumi Habata, Sachiko Miyamoto, Mitsuko Nakashima, Shigeo Takashima, Yukihiko Kawasaki, Nobuyuki Shimozawa and Hirotomo Saitsu in Child Neurology Open</p

    sj-pdf-1-cno-10.1177_2329048X211048613 - Supplemental material for Novel <i>HSD17B4</i> Variants Cause Progressive Leukodystrophy in Childhood: Case Report and Literature Review

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    Supplemental material, sj-pdf-1-cno-10.1177_2329048X211048613 for Novel HSD17B4 Variants Cause Progressive Leukodystrophy in Childhood: Case Report and Literature Review by Akiyo Yamamoto, Shinobu Fukumura, Yumi Habata, Sachiko Miyamoto, Mitsuko Nakashima, Shigeo Takashima, Yukihiko Kawasaki, Nobuyuki Shimozawa and Hirotomo Saitsu in Child Neurology Open</p

    Contrast-enhanced CMR in patients after percutaneous closure of the left atrial appendage: A pilot study

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    Abstract Background To evaluate the feasibility and value of first-pass contrast-enhanced dynamic and post-contrast 3D CMR in patients after transcatheter occlusion of left atrial appendage (LAA) to identify incorrect placement and persistent leaks. Methods 7 patients with different occluder systems (n = 4 PLAATO; n = 2 Watchman; n = 1 ACP) underwent 2 contrast-enhanced (Gd-DOTA) CMR sequences (2D TrueFISP first-pass perfusion and 3D-TurboFLASH) to assess localization, artifact size and potential leaks of the devices. Perfusion CMR was analyzed visually and semi-quantitatively to identify potential leaks. Results All occluders were positioned within the LAA. The ACP occluder presented the most extensive artifact size. Visual assessment revealed a residual perfusion of the LAA apex in 4 cases using first-pass perfusion and 3D-TurboFLASH indicating a suboptimal LAA occlusion. By assessing signal-to-time-curves the cases with a visually detected leak showed a 9-fold higher signal-peak in the LAA apex (567 ± 120% increase from baseline signal) than those without a leak (61 ± 22%; p Conclusion This CMR pilot study provides valuable non-invasive information in patients after transcatheter occlusion of the LAA to identify correct placement and potential leaks. We recommend incorporating CMR in future clinical studies to evaluate new device types.</p
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