3,972 research outputs found
How common can the origin of clusters Cha I, Cha II, epsilon Cha and eta Cha be?
No full textThe trajectories of the clusters Cha, Cha and Cha I, Cha
II, constructed backward in time, have been studied. We concluded that the
hypothesis about the joint formation of all four of these clusters from one
molecular cloud cannot be completely excluded. However, 10-15 Myr ago, all
these four clusters were located at approximately the same height above the
plane of the Galaxy. Thus, the gas-dust clouds from which all these four
clusters were formed were located on one broad front. It is possible that the
appearance of the Cha I, Cha II, Cha and Cha clusters may be
associated with the impact on such a front of shock waves formed after
supernova explosions in the Scorpius-Centauri association. New estimates of the
kinematic ages of the clusters Cha I and Cha II are obtained as
and , respectively. It is shown that the minimum size of the Cha
I-north and Cha I-south clusters corresponded to the time of Myr
and Myr ago, respectively, and approximately 1.5 Myr ago the
distance between the trajectories of these two groupings was minimal.Comment: 9 pages, 5 figures, 1 table, accepted to Research in Astron. and
Astrophy
UVES spectra of young brown dwarfs in Cha I: Radial and rotational velocities
No full textBased on high-resolution UVES spectra we found that
the radial velocity (RV) dispersion of nine of
twelve known young bona fide and candidate brown dwarfs
in the Cha I dark cloud is 2.0 km s-1, i.e.
significantly smaller than
the RV dispersion of T Tauri stars
in Cha I (3.6 km s-1) and only slightly
larger than the dispersion
of the surrounding molecular
gas (1.2 km s-1) (Mizuno et al. [CITE]).
This result indicates that the majority of these brown dwarfs
are not ejected with high velocity out of a dense
region as proposed by some formation scenarios for brown dwarfs.
The mean RV values are consistent with
the objects being kinematic members of Cha I.
The RV dispersion of the T Tauri stars confined to the Cha I
region is based on a
compilation of T Tauri stars
with known RVs from the literature plus
three T Tauri stars
observed with UVES and unpublished RVs for nine T Tauri stars.
Time-resolved spectroscopy revealed RV variations for
five out of nine of the bona fide and candidate
brown dwarfs in Cha I,
which could be due to orbiting planets or surface features.
Furthermore we derived rotational velocities
and the Lithium 6708 Å equivalent width
CHA CHA DANS EĞİTİMİNİN KARDİYO-RESPİRATUVAR PARAMETRELER ÜZERİNE ETKİLERİ
No full textBu çalışmada, 5-9 yıldır dans eden ve eşli dans eğitimine yeni başlayan bireylere uygulanan üç aylık Latin Amerikan Dansı “Cha Cha” (LAD “Cha Cha”) eğitiminin antropometrik ve kardiyo-respiratuvar fonksiyonlar üzerine etkileri analiz ederek ortaya koymak amaçlanmıştır. Çalışmaya, 18-25 yaş aralığında 24 birey gönüllü olarak katılmış ve 3 gruba ayrılmıştır: I-Kontrol grubu, II: Eğitim grubu, III: Dansçı grup. Grup II ve III’e 3 ay süresince ‘Cha Cha’ dans eğitimi verilmiş, sedanter grup ise hiçbir egzersiz çalışmasına alınmamıştır. Bireylerin araştırmanın başında ve 3 ay sonrasında; Antropometrik karakteristikleri (vücut ağırlığı, vücut kitle indeksi (VKİ), yağlı vücut ağırlığı (YVA), yağsız vücut ağırlığı (VYA), vücut yağ yüzdesi (VYY), toplam deri kıvrım kalınlığı (TDKK) ve Kardiyorespiratuvar parametreleri (maksimum oksijen miktarı (VO2max), solunum gaz değişim oranı (R), solunum dakika hacmi (VE), tidal volüm (VT), dakika solunum sayısı (RR), kalp atım hızı (HR), sistolik kan basıncı (SBP), diyastolik kan basıncı (DBP), maksimum egzersize dayanma süresi ve maksimum egzersizde ulaşılabilen en yüksek güç (Wmax)) ölçülmüştür. Deri kıvrım kalınlığı ölçümlerinde “skinfold kaliper”, egzersiz testinde ve spirometrik ölçümlerde “Sensormedics Vmax 29C” kullanılmıştır. 3 aylık “Cha Cha” eğitimi öncesi ve sonrası antropometrik ve kardiyorespiratuvar değerlerin grup içi karşılaştırmalarında t-testi, çoklu karşılaştırmalarda ANOVA ve Post Hoc Testi uygulanmıştır. Sonuç olarak, 3 aylık “Cha Cha” eğitiminin, dans sporuyla uğraşı süresine bağlı olarak aerobik kapasiteyi arttırdığı ifade edilebili
<i>Cha</i>-<i>Koji</i>, comprising green tea leaves fermented with <i>Aspergillus luchuensis var kawachii kitahara</i>, increases regulatory T cell production in mice and humans
No full textGreen tea leaves fermented with Aspergillus luchuensis var kawachii kitahara (Cha-Koji) are a health food containing live A. luchuensis. In this study, we examined the effects of Cha-Koji on the immune system and the enteric environment. First, we designed a clinical trial; after ingesting Cha-Koji daily for 28 days, blood parameters and the fecal composition of the participants were analyzed. Similarly, mice were administered (oral administration) with Cha-Koji suspension or its vehicle for 14 days. Thereafter, both humans and mice were examined by analyzing their immune cell phenotypes and intestinal microbiota. Regulatory T cell (Treg) numbers were significantly increased after administering Cha-Koji. An increase of Clostridium subcluster XIVa, that were known to be rich in butyrate-producing bacterium, was observed in human feces, but not in mice. These results suggest that Cha-Koji has the ability to increase Treg production in both humans and mice, irrespective of the presence of enteric butyrate. “Cha-Koji” increases regulatory T cells in mice and humans.</p
<i>Cha</i>-<i>Koji</i>, comprising green tea leaves fermented with <i>Aspergillus luchuensis var kawachii kitahara</i>, increases regulatory T cell production in mice and humans
No full textAbstract
Green tea leaves fermented with Aspergillus luchuensis var kawachii kitahara (Cha-Koji) are a health food containing live A. luchuensis. In this study, we examined the effects of Cha-Koji on the immune system and the enteric environment. First, we designed a clinical trial; after ingesting Cha-Koji daily for 28 days, blood parameters and the fecal composition of the participants were analyzed. Similarly, mice were administered (oral administration) with Cha-Koji suspension or its vehicle for 14 days. Thereafter, both humans and mice were examined by analyzing their immune cell phenotypes and intestinal microbiota. Regulatory T cell (Treg) numbers were significantly increased after administering Cha-Koji. An increase of Clostridium subcluster XIVa, that were known to be rich in butyrate-producing bacterium, was observed in human feces, but not in mice. These results suggest that Cha-Koji has the ability to increase Treg production in both humans and mice, irrespective of the presence of enteric butyrate.</jats:p
<i>T</i>. <i>gondii</i>-specific antibody responses.
No full textT. gondii-specific IgG, IgG1 and IgG2a were determined in mice sera after challenge infection. Higher levels of IgG and IgG2a were found in multi-antigen VLPs (Multi-antigen Cha) or combination VLPs (Combination Cha) immunized mice compared to naïve challenged mice (Naïve Cha) (A and C, *P T. gondii-specific IgA antibody response was determined from mice feces (D). VLPs vaccination showed higher level of IgA response in both Multi-antigen Cha and Combination Cha compared to Naïve Cha (D, *P < 0.01).</p
147. Przyspieszona hiperfrakcjonowana radioterapia z planowaną przerwą (CHA-CHA) chorych na zaawansowane raki regionu głowy i szyi
No full textZałożenia i cel pracyWyniki leczenia zaawansowanych raków regionu głowy i szyi nie są satysfakcjonujące i konwencjonalna radioterapia w ich przypadku jest zwykle niewydolna. Skłania to do podjęcia prób niekonwencjonalnego frakcjonowania dawki. Celem naszej pracy była ocena skuteczności przyspieszonego hiperfrakcjonowanego napromieniania z planowaną przerwą (CHA-CHA).Materiał i metodykaMateriał obejmuje 27 chorych (22 M, 5 K) na zaawansowane (T2N2c-3, T3-4 N2-3), nieoperacyjne raki płaskonabłonkowe regionu głowy i szyi (11- rak gardła środkowego, 9-rak krtani, 6-rak języka, 1-rak gardła dolnego), będących grupą pilotową kontrolowanego randomizowanego badania klinicznego. Wszyscy chorzy byli w dobrym stanie ogólnym (Zubrod <= 2). Średni wiek wynosił 56 lat (44–70). Chorzy byli leczeni fotonami X 6 MV, przy użyciu dawki frakcyjnej 1,6 Gy, podawanej 2 razy dziennie do dawki całkowitej 64 Gy. W celu uniknięcia przyspieszonej repopulacji leczenie kończono w 28 dni, a w środku wprowadzono 8 dniowa przerwę dla regeneracji śluzówki. Oceniono toksyczność leczenia oraz przeżycie chorych. Przeprowadzono analizę zależności pomiędzy długością przeżycia, a różnymi czynnikami biologicznymi i fizycznymi.WynikiŻaden chory nie przerwał leczenia z powodu jego toksyczności. Najwyższe nasilenie ostrego odczynu popromiennego oceniane w skali Dische wystąpiło w 3 i 4 tygodniu leczenia i zawierało się w przedziale od 6 do 25 punktów (średnia 16). Przeprowadzona analiza wykazała w okresie 50 miesięcy 34% przeżyć całkowitych i 41% przeżyć po wyłączeniu zgonów spowodowanych rozsiewem odległym. Nie stwierdzono zależności pomiędzy długością przeżycia, a cechami T i N, wielkością guza i przerzutowo zmienionych węzłów oraz stopniem regresji po leczeniu.WnioskiOtrzymane wyniki pozwalają na sformułowanie wniosku, że CHA-CHA jest bezpiecznym i wartościowym schematem leczenia chorych na zaawansowane raki regionu głowy i szyi oraz uzasadniają przeprowadzenie kolejnej, randomizowanej fazy,badanla
The effects of cha cha dance training on cardio-respiratory parameters
No full textBu çalışmada, 5-9 yıldır dans eden ve eşli dans eğitimine yeni başlayan bireylere uygulanan üç aylık Latin Amerikan Dansı "Cha Cha" (LAD "Cha Cha") eğitiminin antropometrik ve kardiyo-respiratuvar fonksiyonlar üzerine etkileri analiz ederek ortaya koymak amaçlanmıştır. Çalışmaya, 18-25 yaş aralığında 24 birey gönüllü olarak katılmış ve 3 gruba ayrılmıştır: l-Kontrol grubu, II: Eğitim grubu, III: Dansçı grup. Grup II ve lll'e 3 ay süresince 'Cha Cha' dans eğitimi verilmiş, sedanter grup ise hiçbir egzersiz çalışmasına alınmamıştır. Bireylerin araştırmanın başında ve 3 ay sonrasında; Antropometrik karakteristikleri (vücut ağırlığı, vücut kitle indeksi (VKİ), yağlı vücut ağırlığı (YVA), yağsız vücut ağırlığı (VYA), vücut yağ yüzdesi (VYY), toplam deri kıvrım kalınlığı (TDKK) ve Kardiyo-respiratuvar parametreleri (maksimum oksijen miktarı (V02max), solunum gaz değişim oranı (R), solunum dakika hacmi (VE), tidal volüm (VT), dakika solunum sayısı (RR), kalp atım hızı (HR), sistolik kan basıncı (SBP), diyastolik kan basıncı (DBP), maksimum egzersize dayanma süresi ve maksimum egzersizde ulaşılabilen en yüksek güç (Wmax)) ölçülmüştür. Deri kıvrım kalınlığı ölçümlerinde "skinfold kaliper", egzersiz testinde ve spirömetrik ölçümlerde "Sensormedics Vmax 29C" kullanılmıştır. 3 aylık "Cha Cha" eğitimi öncesi ve sonrası antropometrik ve kardiyorespiratuvar değerlerin grup içi karşılaştırmalarında t-testi, çoklu karşılaştırmalarda ANOVA ve Post Hoc Testi uygulanmıştır. Sonuç olarak, 3 aylık "Cha Cha" eğitiminin, dans sporuyla uğraşı süresine bağlı olarak aerobik kapasiteyi arttırdığı ifade edilebilir.Purpose of this study was to analyze and demonstrate effects of 3 month 'Cha Cha' training on anthropometric and cardiorespiratory functions of 5-9 years dancing dancers and beginners of dance training groups. 24 subjects participated in this study voluntarily (age 18-25 years) and they were divided into 3 groups: group I: Control group, group II: Training group and group III: Dancer group. Group II and group III were undertaken into 'Cha Cha' dance training for three months. Sedentary group does not have any regular exercise program. Anthropometric (body weight, body muscle index (BMI), fat mass (FM), fat free mass (FFM), body fat percent (BF %), total skinfold thickness) and cardio-respiratory (maximal oxygen uptake (V02max), respiratory exchange ratio (R), minute respiration volume (VE), tidal volume (Tv), minute respiration number (RR), heart rate (HR), systolic blood pressure (SBP), diastolic olood pressure (DBP)) measurements were taken from the subjects before and after their 3 month training program. Skinfold measurements were done by skinfold caliper and exercise measurements were done by Sensormedics Vmax 29C. Anthropometric and cardio-respiratory values before and after 3 month training in sedentary, dance learning and dancer groups were compared within and among the groups by using t-test, ANOVA and Post Hoc Test for multiple comparements if it is applicable. In conclusion, it can be said that 3 rinonth Cha Cha training caused significant progress in aerobic capacity value according to training year
Lean NOx Capture and Reduction by NH3 via NO+ Intermediates over H-CHA at Room Temperature
No full textThe oxidation of NO to NO2 and the subsequent reduction by NH3 via a NO+ intermediate over a proton-type chabazite zeolite (H-CHA) were investigated by the combination of in situ infrared (IR) spectroscopy and density functional theory (DFT) calculations. The in situ IR spectral results indicate that the NO' species formed under a flow of NO + O-2 at 27-250 degrees C are more stable at lower temperatures over both H-CHA and copper-cation-exchanged CHA zeolite (Cu-CHA). The Arrhenius plot (T = 27-120 degrees C) shows a negative apparent activation barrier energy (-11.5 kJ mol(-1)) for the formation of NO+ species under the NO + O(2 )flow over H-CHA. The time course of the IR spectra at 27 degrees C shows that NO is oxidized by O-2 to NO2 and then further converted via N2O4 to NO+ and NO3. The subsequent exposure to NH3 at 27 degrees C reduces the NO species to N-2. DFT calculations revealed that Bronsted acid sites in zeolite pores promote the dissociation of N2O4 intermediates into NO and NO3- species with a low activation barrier (15 kJ mol(-1)). Moreover, the computed activation barrier for the reduction of NO+ species by NH3 was considerably low (6 kJ mol(-1)). The experimental and theoretical results of this study demonstrate the high potential of Cu-free H-CHA zeolites for promoting lean NOx capture to form NO+ species and the subsequent reduction by NH3 at room temperature
Classification of adenosine receptors mediating antinociception in the rat spinal cord
No full textAnalogues of adenosine were injected intrathecally into rats implanted with chronic indwelling cannulae in order to determine a rank order of potency and hence characterize adenosine receptors involved in spinal antinociception. In the tail flick test L-N6-phenylisopropyl adenosine (L-PIA), cyclohexyladenosine (CHA) and 5'-N-ethylcarboxamide adenosine (NECA) produced dose-related antinociception which attained a plateau level. NECA and CHA also produced an additional distinct second phase of antinociception. D-N6-Phenylisopropyl adenosine (D-PIA) and 2-chloroadenosine (CADO) had very little antinociceptive activity in this test. The rank order of potency in producing the plateau effect was L-PIA greater than CHA greater than NECA greater than D-PIA = CADO, while that for the second phase of antinociception was NECA greater than-CHA. Pretreatment with both theophylline and 8-phenyltheophylline (8-PT) antagonized antinociception produced by CHA, with 8-PT being at least an order of magnitude more potent than theophylline. Both antagonists produced a significant hyperalgesia in the tail flick test. L-PIA and CHA also produced methylxanthine-sensitive antinociception in the hot plate test. These results suggest that activation of A1-receptors in the spinal cord can produce antinociception. Activation of A2-receptors may produce an additional effect, but the relative activity of CHA in this component of activity is unusual.LR: 20061115; PUBM: Print; JID: 7502536; 0 (Receptors, Cell Surface); 0 (Receptors, Purinergic); 146-77-0 (2-Chloroadenosine); 29193-86-0 (Phenylisopropyladenosine); 35920-39-9 (Adenosine-5'-(N-ethylcarboxamide)); 36396-99-3 (N(6)-cyclohexyladenosine); 58-55-9 (Theophylline); 58-61-7 (Adenosine); 961-45-5 (8-phenyltheophylline); ppublishSource type: Prin
- …
