265,533 research outputs found

    2022 Resident Scholar Reflection: Liz Hutter

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    Liz Hutter, an assistant professor of English at the University of Dayton, received the Marian Library Resident Scholar Fellowship for the project “Reading, Writing, and Seeing Health and Disability in Community at Lourdes Sanctuary.” An account from the writer Flannery O’Connor, whose cousin suggested a pilgrimage to Lourdes as a healing intervention for a chronic illness, prompted Hutter’s interest in pursuing what she sees as a binary logic often associated with Lourdes, the shrine commemorating the 1858 apparitions of the Virgin Mary to Bernadette Soubirous. O’Connor made a distinction clear to her cousin: “I am going as a pilgrim, not a patient.” Religious beliefs and spiritual practices play a role in how many people understand their illnesses or disabilities, Hutter posits. At the same time, religious institutions and spiritual communities are commonly involved in health promotion and communication around illness and disability. These individual beliefs and institutional practices merge on the therapeutic and spiritual landscape of the Lourdes sanctuary. Using materials and expertise in the Marian Library, she plans to examine Lourdes from multiple disciplines as not only a place for individual reflection and healing, but also as a space for examining community relationships and access to community services for persons with neurological, physical, sensory and other disabilities. By employing a disability studies perspective, she says, she plans to destabilize the rigid distinction O’Connor articulated between pilgrim and patient

    Natural variation in Drosophila melanogaster

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    This work is dedicated to studying natural variation in D. melanogaster at the DNA sequence and gene expression level. In addition I present a new version of the DNA polymorphism analysis program VariScan, which includes significant improvements. In CHAPTER 1 I describe a genome scan of single nucleotide polymorphism in two natural D. melanogaster populations (from Africa and Europe) on the third chromosome. Together with polymorphism data previously published for the X chromosome of the same populations, this allows a comparative study of the polymorphism patterns of the X chromosome and an autosome. The frequency spectrum of mutations and the patterns of linkage disequilibrium are investigated. The observed patterns indicate that there is a significant difference in the behavior of the two chromosomes, as has already been suggested by previous studies. To uncover the reasons for this a coalescent based maximum likelihood method is applied that incorporates the effects of demographic history and unequal sex ratios. For the African population the differential behavior of the chromosomes can be explained by its demographic history and an excess of females. In Europe, a population bottleneck and an excess of males alone cannot explain the patterns we observe. The additional action of positive selection in this population is proposed as a possible explanation. In CHAPTER 2 I investigate the variation in gene expression of the two aforementioned populations. Whole-genome microarrays are used to study levels of expression for 88% of all known genes in eight adult males from both populations. The observed levels of expression variation are equal in Africa and Europe, despite the fact that DNA sequence variation is much higher in Africa. This is evidence for the action of stabilizing selection governing levels of expression polymorphism. Supporting this view, genes involved in many different functions, and are therefore on strong selective constraint, show less variation than do genes with only few functions. The experimental design allows the search for genes which differ in their expression patterns between Europe and Africa and might therefore have undergone adaptive evolution. Detected candidates include genes putatively involved in insecticide resistance and food choice. Surprisingly, many genes over-expressed in Africa are involved in the formation and function of the flying apparatus. In CHAPTER 3 I present version 2 of the program VariScan. This program was designed to analyse patterns of DNA sequence polymorphism on a chromosomal scale. The functionality of the core analysis tool, the wavelet decomposition, is described. In addition, multiple improvements to the previous version are presented. The program now supports the “pairwise deletion” option. This is essential for analysing data at the chromosome scale, since such data often contains incomplete information. It is now possible to add outgroup information, which allows the calculation of additional statistics. Furthermore, the separate analysis of different predefined chromosomal regions is added as an option. To increase the user friendliness, a graphical user interface is now included as part of the software package. Finally, VariScan is applied to published and computer-generated data and the ability of the wavelet-based analysis to uncover chromosomal regions with interesting DNA polymorphism patterns is demonstrated

    Irmgard Hutter, Corpus der byzantinischen Miniaturenhandschriften. I. Oxford Bodleian Library. I.

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    Walter Christopher. Irmgard Hutter, Corpus der byzantinischen Miniaturenhandschriften. I. Oxford Bodleian Library. I.. In: Revue des études byzantines, tome 38, 1980. pp. 322-324

    Irmgard Hutter, Corpus der byzantinischen Miniaturenhandschriften. I. Oxford Bodleian Library. I.

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    Walter Christopher. Irmgard Hutter, Corpus der byzantinischen Miniaturenhandschriften. I. Oxford Bodleian Library. I.. In: Revue des études byzantines, tome 38, 1980. pp. 322-324

    Cadets Hutter, Morgan and Morrison, August 1859

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    Three cadets from the Class of 1860: James Risque Hutter, William Henry Morgan, and James Horace Morrison. The image shown here is a digital copy of the original owned by and used with permission of the Historic Sandusky Foundation (Lynchburg, VA). The original is an ambrotype; inside the case is inscribed: "W. H. Morgan 1st Capt. J. H. Morrison 1st Lieut. J. R. Hutter 2d Capt. Taken August 25th, 1859 – During encampment 1st classmen. Each paid a third part & played at cards the best three out of five games and I won it. J. R. Hutter

    Disputatio Theologica I. De Scriptura Sacra, Complectens examen opinionum Papisticarum De Scripturarum Canone, Eius Constitutione, Et Ipsis libris Canonicis

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    Quam ... Sub Praesidio ... Leonharti Hutteri ... exhibet M. Polycarpus Lyserus Witenergensis. ad diem 22. Febr. ...In: Hutter, Leonhard: Controversia I. Generalis De Verbo Dei Scripto, Et Traditionibus Non- Scripti

    Irmgard Hutter. Corpus der byzantinischen Miniaturenhandschriften. Band 1. Oxford, Bodleian Library, I

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    Lafontaine-Dosogne Jacqueline. Irmgard Hutter. Corpus der byzantinischen Miniaturenhandschriften. Band 1. Oxford, Bodleian Library, I. In: Scriptorium, Tome 33 n°2, 1979. pp. 323-324

    Irmgard Hutter. Corpus der byzantinischen Miniaturenhandschriften. Band 1. Oxford, Bodleian Library, I

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    Lafontaine-Dosogne Jacqueline. Irmgard Hutter. Corpus der byzantinischen Miniaturenhandschriften. Band 1. Oxford, Bodleian Library, I. In: Scriptorium, Tome 33 n°2, 1979. pp. 323-324

    I. Ševčenko and I. Hutter (éd.), ΑΕΤΟΣ. Studies in honour of Cyril Mango presented to him on April 14, 1998

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    Cacouros Michel. I. Ševčenko and I. Hutter (éd.), ΑΕΤΟΣ. Studies in honour of Cyril Mango presented to him on April 14, 1998. In: Revue des études byzantines, tome 57, 1999. pp. 328-329

    Disputatio Theologica X. De Autoritate Patrum Et Conciliorum,

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    Quam ... Sub Praesidio ... Leonharti Hutteri ... proponit M. Aegidius Strauchius, Witebergensis. Ad diem 7. Maii ...In: Hutter, Leonhard: Controversia I. Generalis De Verbo Dei Scripto, Et Traditionibus Non- Scripti
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