2,643 research outputs found

    Natural Variation of the Circadian Clock in Neurospora

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    Most living organisms on earth experience daily and expected changes from the rotation of the earth. For an organism, the ability to predict and prepare for incoming stresses or resources is a very important skill for survival. This cellular process of measuring daily time of the day is collectively called the circadian clock. Because of its fundamental role in survival in nature, there is a great interest in studying the natural variation of the circadian clock. However, characterizing the genetic and molecular mechanisms underlying natural variation of circadian clocks remains a challenging task. In this chapter, we will summarize the progress in studying natural variation of the circadian clock in the successful eukaryotic model Neurospora, which led to discovering many design principles of the molecular mechanisms of the eukaryotic circadian clock. Despite the success of the system in revealing the molecular mechanisms of the circadian clock, Neurospora has not been utilized to extensively study natural variation. We will review the challenges that hindered the natural variation studies in Neurospora, and how they were overcome. We will also review the advantages of Neurospora for natural variation studies. Since Neurospora is the model fungal species for circadian study, it represents over 5 million species of fungi on earth. These fungi play important roles in ecosystems on earth, and as such Neurospora could serve as an important model for understanding the ecological role of natural variation in fungal circadian clocks.Advances in Genetics, Vol. 99

    Corrigendum to “A generic multi-level framework for microscopic traffic simulation with automated vehicles in mixed traffic” [Transport. Res. Part C: Emerg. Technol. 110 (2020) 291–311] (Transportation Research Part C (2020) 110 (291–311), (S0968090X19304322), (10.1016/j.trc.2019.11.019))

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    The authors regret that a contributing author was missing from the list of authors. The complete list of authors should be: “S.C. Calvert, B. van Arem, & J. W. C. van Lint”. All are with Delft University of Technology, Department of Transport & Planning, The Netherlands updated as above. The authors would like to apologise for any inconvenience caused.Transport and Plannin

    (1(4):1-10)The Effects of Granosan Treatment for the Control of Some Seed-borne Diseases of Rice

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    1.榖仁樂生溶液浸種一小時,其濃度爲0.05%時,可消滅稻熱病病菌;0.07%時可使胡麻斑病及馬鹿菌病病原菌致死。田間試驗結果本藥液浸種消毒,防除馬鹿苗病有顯著之效果。 2.根據病斑消毒試驗結果,0.3%濃度之藥液可消滅病斑組織內之病原,又用以噴霧稻株亦得相同之結果。 3.浸種藥液之濃度,不論0.07%或0.1%,對種子發芽均有良好結果,對幼苗生長情形,則標準區與處理區間無顯著之差異。 4.穀化樂生溶液浸種消毒較本省過去所用之Uspulun或甲醛溶液爲簡便,因藥劑用量少,浸潰時間短是其長處。1. Granosan water solution was recommeded as seed disinfectant for the control of some seed-borne disesaes of rice. One hour of immersion at the concentration of 0.05 per cent was found effective for killing Piricularia Oryzae and of 0.07 per cent has also been productive of good result for controlling Helminthos porium oryzae and Gibberella Fujikuroi. While under field erperiment the latest ones produced the most significant benefit. 2. The internal mycelium of P. oryzae and H. oryzae were both killed as soon as the affected leaf lesions have been swiftly washed through the Granosan solution at the concentration of 0.3 per cent. Similar results were obtained by spraying on ”blast” affected plants. 3. Whatever the concentration of Granosan solution at 0.07 or 0.1 per cent all the treated seeds shown better germination without any toxical injuries

    Atsushi Nakajima and Yakumo Koizumi

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    中島敦(1909-1942)是昭和初期的作家,年僅三十三歲即因宿疾氣喘而病故。留下的作品數雖然不多,但其作品〈山月記〉;〈弟子〉;〈李陵〉等曾多次被收錄於日本高中的國語教科書中而廣為人所知。另一方面,小泉八雲(原名拉夫卡迪奧.赫恩,1850-1904)原為英國籍新聞記者,1887-1889年間曾至法屬西印度群島旅行,1890年時為採訪而赴日,之後因深愛日本傳統文化而放棄記者的工作留在日本教書,並於1896年時歸化為日本籍。小泉赴日後的著作內容多以描述日本風物與日本傳統文化,以及記載民話等口述文學為主,其中家喻戶曉的《怪談》一書至今仍膾炙人口。 中島敦與小泉八雲之間,乍看之下兩者並無任何關聯,但中島敦作品裡的許多創作元素其實是源自於小泉八雲的作品。本文將從研究中島敦的初登文壇之作〈光與風與夢〉與小泉八雲的作品《法屬西印度群島的兩年間》之關聯性開始,探究中島敦作品與小泉八雲作品之間的影響關係。In the past, researchers believed that Atsushi Nakajima's “the Light, the Wind, and the Dream” was created based on the associated materials of Robert Louis Stevenson's works, essays, critical biographies, letters, and so on. This text reexamines the materials of “the Light, the Wind, and the Dream” by analyzing Atsushi Nakajima's inventory of books and his pocketbooks. From this information, we learn Nakajima deepened his yearn for the South after his trip to the Ogasawara Islands, and therefore started to read Lafcadio Hearn's Two Years in the French West Indies while he finished his trip back to Yokohama. While Nakajima wrote “the Light, the Wind, and the Dream”, he obviously didn't just take the materials associated with Robert Louis Stevenson, but also introduced his own experiences of the Ogasawara Islands into his work. Moreover, through the comparison of “the Light, the Wind, and the Dream” and the Two Years in the French West Indies, we shall see that Nakajima learned the technique of portrait and the sensation of tropical islands from Lafcadio Hearn's Two Years in the French West Indies, and presented these techniques in “the Light, the Wind, and the Dream”

    Towards the Holy Grail: combining system dynamics and discrete-event simulation in healthcare

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    The idea of combining discrete-event simulation and system dynamics has been a topic of debate in theoperations research community for over a decade. Many authors have considered the potential benefits ofsuch an approach from a methodological or practical standpoint. However, despite numerous examples ofmodels with both discrete and continuous parameters in the computer science and engineering literature,nobody in the OR field has yet succeeded in developing a genuinely hybrid approach which truly integratesthe philosophical approach and technical merits of both DES and SD in a single model. In this paperwe consider some of the reasons for this and describe two practical healthcare examples of combinedDES/SD models, which nevertheless fall short of the “holy grail” which has been so widely discussed inthe literature over the past decade

    Exploration of Jyun Takami's Southern Works: Comparison With Takami Jyun's Dairies (I)

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    日本近代的南方風潮中,許多作家、文人前往南方並留下大量與南方相關的作品及紀錄。作家高見順也是其中之一。他在昭和十年代曾有兩次前往南洋的經驗,第一次是在昭和十一年的一月至五月,與作家友人三雲祥之助同行前往當時的荷屬東印度旅遊,另一次是昭和十六年十二月至十八年一月,以徵用作家的身份被派遣至緬甸,經歷約莫兩年的從軍生活。經歷這兩次的南洋體驗,高見順寫下〈蘭印的印象〉、〈蘭印點描〉、〈朝南之旅〉、〈緬甸記〉等大量的作品。 在南洋的這段期間,高見順亦留下了詳盡的日記。據高見順自己所言,留下這些日記的目的是為了當作日後書寫作品的題材。然而,雖說這些與南洋相關的作品內容都是高見順依據自己當時所留下的日記為基礎加以增刪修改書寫而成,但從其公開發表的作品與其私人的日記當中,可發現兩者在內容描述上的明顯差異。本論文將以高見順的蘭印相關作品為探討對象,將高見順於當時公開發表的作品與其日記相比較,分析兩者的異同之處並探討其背後所隱含的意義。In Japan's modern history of the Southern trend, many writers and scholars headed to the South and left lots of works and records associated with the South. Writer Jyun Takami was one of them. He had two trips to the Southeast Asia in the Showa generation, the first trip to Dutch East Indies with his friend Syounosuke Mikumo from January to May, the 16th year of the Showa Generation. The second trip was to Myanmar for 2 years of military life as a dispatched writer from December, the 16th year to January, the 18th year of Showa generation. After these two experiences, Jyun Takami wrote lots of works such as ‘the Impression of Dutch East Indies’, ‘the Sketch of Dutch East Indies’, ‘Journey to the South’ and ‘Myanmar Note’. During this period, Takami also left a detailed diary along. According to Jyun Takami, these diaries were intended to be subjects for future writing. However, although these works associated with the Southern contents were written based on adjustment of Takami's own diaries, one can tell the significant differences between the published works and the private diaries. Using Takami's associated works of Dutch East Indies as the discussion topic, this paper will compare Takami's published works with his private diaries and analyze the differences while exploring the meaning hidden beyond

    Exploration of Jyun Takami's Southern Works--- Comparison With Jyun Takami's Dairies (2)---

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    日本近代的南方風潮中, 許多作家、文人前往南方並留下大量與南方相關的作品及紀錄。作家高見順也是其中之一。他在昭和十年代曾有兩次前往南洋的經驗, 第一次是在昭和十一年的一月至五月,與友人三雲祥之助同行前往當時的荷屬東印度旅遊, 另一次是昭和十六年十二月至十八年一月,以徵用作家的身份被派遣至緬甸,經歷一年多的隨軍生活。以此次的隨軍派遣為契機,高見順再次開始撰寫在第一次的南洋行之後因回到內地而一度中斷的日記,同時,藉由這段隨軍的南洋體驗, 高見順也寫下《緬甸記》、〈緬甸雜記〉、〈緬甸的印象〉等大量的作品。 本文將以高見順的徵用期作品為探討對象, 配合當時的時代背景並對照高見順於同時期所撰寫的日記,探討高見順在其徵用期作品裡所呈現出的南方言說及其意義。In Japan's modern history of the Southern trend, many writers and scholars headed to the South and left lots of works and records associated with the South. Writer Jyun Takami was one of them. He had two trips to the Southeast Asia in the Showa generation, the first trip to Dutch East Indies with his friend Syounosuke Mikumo from January to May, the 16th year of the Showa Generation. The second trip was to Myanmar for 1 years of military life as a dispatched writer from December, the 16th year to January, the 18th year of Showa Generation. During the period of conscription, Jyun Takami wrote lots of works such as “Burma Note”, “Miscellaneous Notes of Burma”, and “the Impression of Burma”. Using Takami's associated works which were written during the period of conscription as the discussion topic, this paper, on the back of the prevailing era, will compare Takami's published works with his private diaries and analyze the discourse about the South in his works
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