24,204 research outputs found
Rapid classification and identification of chemical compositions of Pu-zhi-hui-ling decoction by UHPLC-Q-Orbitrap HRMS
No full textPu-zhi-hui-ling decoction (PZHLD) is a traditional Chinese medicine (TCM) formula for the treatment of Alzheimer’s disease (AD), but its chemical composition has not been reported. In this study, we aimed to establish a mass spectrometry (MS) analysis method for rapid classification and identification of the chemical constituents in PZHLD. The sample was analysed by ultrahigh-performance liquid chromatography coupled to quadrupole Orbitrap high-resolution mass spectrometry (UHPLC-Q-Orbitrap HRMS). The chemical constituents of PZHLD were identified based on accurate MS data, fragmentation characteristics of MS/MS, and reference information described in the literature. A total of 123 chemical constituents were identified. In addition, we summarised the fragmentation pathways of the chemical constituents in PZHLD. Our finding might lay the foundation for the further pharmacodynamic study and clinical application of PZHLD.</p
A Fourier-related FE2 Multiscale Model for Instability Phenomena of Long Fiber Reinforced Materials
No full textQ&A with Guang-Hui Liu
No full textWe at Cell Reports discuss with Guang-Hui Liu his work with the mechanisms and interventions of aging, in particular, recent work regarding the resurrection of endogenous retroviruses in neurons in primates
q-Differential equations for q-classical polynomials and q-Jacobi-Stirling numbers
No full textWe introduce, characterise and provide a combinatorial interpretation for the so-called q-Jacobi–Stirling numbers.
This study is motivated by their key role in the (reciprocal) expansion of any power of a second order
q-differential operator having the q-classical polynomials as eigenfunctions in terms of other even order operators,
which we explicitly construct in this work. The results here obtained can be viewed as the q-version of
those given by Everitt et al. and by the first author, whilst the combinatorics of this new set of numbers is a
q-version of the Jacobi–Stirling numbers given by Gelineau and the second author
Why are stock market returns correlated with future economic activities?
No full textStock price, because it is a forward-looking variable, forecasts economic activities. An unexpected increase in stock price reflects that (i) future dividend growth is higher and/or (ii) future discount rates are lower than previously anticipated; therefore, the increase predicts higher output and investment. As well, other studies argue for an important relation between the expected stock market return and investment. In this paper, Hui Guo analyzes the relative importance of these mechanisms by using Campbell and Shiller’s (1988) method to decompose stock market return into three parts: expected return, a shock to the expected future return, and a shock to the expected future dividend growth. Contrary to the conventional wisdom, the author finds that dividend shocks are a rather weak predictor for future economic activities. Moreover, the expected return and shocks to the expected future return display different predictive patterns. The results shown here, collectively, explain why the forecasting power of stock market return is rather limited.Stock market
Recommended from our members
Network Q
No full textA press release from Network Q announcing that they will begin featuring Brian McNaught, a gay columnist and author, for a monthly segment
Network Q
No full textA press release from Network Q announcing that they will begin featuring Brian McNaught, a gay columnist and author, for a monthly segment
Tobin's Q and Financial Policy
No full textRecent research in macroeconomics has emphasized the importance of linking the financial and real sectors and the need for working with optimizing models. Tobin’s Q model of investment would appear to provide a framework that can satisfy these two criteria. In contrast to the original presentation of the Q model, the formal development has not recognized that the firm actively participates in a number of financial markets; in this broader context, we show that Q is likely to be an uninformative and possibly misleading signal for investment expenditures . We then endeavor to turn this negative theoretical result to positive advantage in resolving a number of empirical problems with Q models, but the modifications dictated by the theory receive little support from the data.
Characterising hyperbolic hyperplanes of a non-singular quadric in PG (4, q)
No full textLet H be a non-empty set of hyperplanes in PG(4,q), q even, such that every point of PG(4,q) lies in either 0, 1/2q³ or 1/2(q³+q²²) hyperplanes of H, and every plane of PG(4,q) lies in 0 or at least 1/2q hyperplanes of H. Then H is the set of all hyperplanes which meet a given non-singular quadric Q(4, q) in a hyperbolic quadric.S.G. Barwick, Alice M.W. Hui, Wen-Ai Jackson, Jeroen Schillewaer
A Q-learning based multi-strategy integrated artificial bee colony algorithm with application in unmanned vehicle path planning
No full textArtificial bee colony (ABC) is a prominent algorithm that offers great exploration capabilities among various meta-heuristic algorithms. However, its monotonous and one-dimensional search strategy limits its searching performance in the solving process. Thus, to address this issue, a Q-learning based multi-strategy integrated ABC algorithm (QMABC) is proposed. In the QMABC, multiple search strategies are proposed to utilize different individual experiences and search approaches for solution updates. Then, Q-learning is employed for strategy selection. In comparison to previous studies, this paper introduces more effective state and action configurations within the framework of Q-learning. To evaluate the performance of the QMABC, CEC 2017 benchmark functions are adopted to compare it to different meta-heuristic algorithms including ABC based and non-ABC based algorithms. Moreover, applications in path planning are implemented to further verify the effectiveness of the QMABC. Overall, it should be highlighted that the proposed QMABC demonstrates superiority in both numerical and practical experiments.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Discrete Mathematics and Optimizatio
- …
