2,813 research outputs found

    January Gill O\u27Neil, 38th Annual ODU Literary Festival

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    January Gill O\u27Neil is the author of Misery Islands and Underlife, both published by CavanKerry Press. She is the executive director of the Massachusetts Poetry Festival and an assistant professor of English at Salem State University. She is a graduate of Old Dominion University

    Ague conqueror

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    This apothecary card for August Flower, German Syrup displays an illustration of two young girls helping each other with balance. “P.W. Hubbard, Farmington, Me.,” stamped on the front of the card. Circa 1870 through 1920

    Poser

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    Poser is a book of poems consisting of seven sections. The poems inside the book deal with a range of topics, but focus centrally around the development of identity in contemporary society. The work calls to question the paths human beings seek in order to affirm selfhood, and deals heavily with the psychological problem known as "Imposter Syndrome." The sections address distinct periods of development and their corresponding spiritual, social, and human inquiries, which end up defining the shapes of our lives.M.F.A.Includes bibliographical referencesby Evan Gill Smit

    Natural mineral particles are cytotoxic to rainbow trout gill epithelial cells in vitro

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    Worldwide increases in fluvial fine sediment are a threat to aquatic animal health. Fluvial fine sediment is always a mixture of particles whose mineralogical composition differs depending on the sediment source and catchment area geology.Nonetheless, whether particle impact in aquatic organisms differs between mineral species remains to be investigated. This study applied an in vitro approach to evaluate cytotoxicity and uptake of four common fluvial mineral particles (quartz, feldspar, mica, and kaolin; concentrations: 10, 50, 250 mg L21) in the rainbow trout epithelial gill cell line RTgill-W1. Cells were exposed for 24, 48, 72, and 96 h. Cytotoxicity assays for cell membrane integrity (propidium iodide assay), oxidative stress (H2DCF-DA assay), and metabolic activity (MTT assay) were applied. These assays were complemented with cellcounts and transmission electron microscopy. Regardless of mineral species, particles #2 mm in diameter were taken up by the cells, suggesting that particles of all mineral species came into contact and interacted with the cells. Not all particles, however, caused strong cytotoxicity: Among all assays the tectosilicates quartz and feldspar caused sporadic maximum changes of 0.8–1.2-fold compared to controls. In contrast, cytotoxicity of the clay particles was distinctly stronger and even differed between the two particle types: mica induced concentration-dependent increases in free radicals, with consistent1.6–1.8-fold-changes at the 250 mg L21 concentration, and a dilated endoplasmic reticulum. Kaolin caused concentrationdependent increases in cell membrane damage, with consistent 1.3–1.6-fold increases at the 250 mg L21 concentration. All effects occurred in the presence or absence of 10% fetal bovine serum. Cell numbers per se were marginally affected. Results indicate that (i.) natural mineral particles can be cytotoxic to gill epithelial cells, (ii.) their cytotoxic potential differs between mineral species, with clay particles being more cytotoxic, and (iii.) some clays might induce effects comparable to engineered nanoparticles

    Gill R. Role of Flouride on Thyroid Hormone Imbalance. Review Article Role of Flouride on Thyroid Hormone Imbalance –A Mini Review

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    In India, both Iodine Deficiency Disorders (IDD) and fluorosis (due to consumption of excess Corresponding Author fluoride), are the two most prevalent endemic diseases which coexist in certain regions in the Dr. Ravneet Gill country. Fluorosis is associated with delayed tooth Student (Externship) at Family eruption, delayed removal of enamel matrix proteins, delayed enamel maturation etc. W

    Nodular gill disease: a unique form of proliferative gill disease in rainbow trout, Salmo gairdneri Richardson

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    In an outbreak of proliferative gill disease in laboratory rainbow trout fingerlings lesions were multifocal among filaments and uniquely severe in the distal region of affected filaments, forming nodules. This contrasted with the more common forms of proliferative gill disease in Ontario, such as bacterial gill disease, in which lesions are diffuse along and among filaments. The cause is unknown, although cells with a very distinctive morphology were closely associated with the lesions..RE: 22 ref.; SC: ZA; CA; VE; 0V; 0ISource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0140-7775&isbn=&volume=8&issue=6&spage=511&pages=511-522&date=1985&title=Journal%20of%20Fish%20Diseases&atitle=Nodular%20gill%20disease%3a%20a%20unique%20form%20of%20proliferative%20gill%20disease%20in%20rainbow%20trout%2c%20Salmo%20gairdneri%20Richardson.&aulast=Daoust&pid=%3Cauthor%3EDaoust%2c%20P%20Y%3bFerguson%2c%20H%20W%3C%2Fauthor%3E%3CAN%3E19862272504%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3

    Cancer and exercise do mix

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    First paragraph: When you hear the word “cancer” probably the last thing that you think of is physical activity. In fact, most of us think of cancer as a death sentence. Treatments for cancer make many people feel lousy and the side effects of treatment include fatigue, anxiety, nausea, vomiting and pain. So it is hardly surprising that people who are diagnosed with cancer are not reaching for their running shoes or gym kit.  Access this article on The Conversation website: https://theconversation.com/cancer-and-exercise-do-mix-6631

    Teloganodes jacobusi Sartori & Peters & Hubbard 2008, sp. nov.

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    Teloganodes jacobusi Sartori sp. nov. (Figs.20, 21, 27, 34, 42, 47, 61, 62, 87–90, 126–128) Material examined. Holotype: 1 male nymph, Sri Lanka, Nuwara Eliya district, Nuwara Eliya, stream below Lover’s Leap, 2.IV.1978, M. Hubbard [USNM]. Paratypes: 19 nymphs, same data as holotype [MZL, of which 1 partially mounted on slide preparation]; 21 nymphs, same data as holotype, but 19.III.1978 [FAMU], 85 nymphs, Nuwara Eliya, small Lover’s Leap stream, 1.IV.1978, M. Hubbard [66 in FAMU, 2 in AMG, 17 in MZL of which 1 partially mounted on slide preparation]; 25 nymphs, Nuwara Eliya district, Hakgala – Kande Ella, 3.IV.1978, M. Hubbard [FAMU], 41 nymphs, Kandy district, Haloya, Khone Palama, 17.III.1978, M. Hubbard [MZL of which 1 partially mounted on slide preparation], 2 nymphs, Ratnapura District, Belihuloya, Belihul Oya, 9.IV.1978, M. Hubbard [FAMU], 1 nymph, Maskeliya Region, Maskeliya Riv. at base of Adam's Peak, about 1 km above Maskeliya impoundment, 1800 m, 1.XII.1970, F. Starmuehlner [FAMU]. Description. Nymph Body length up to 6.0 mm and 5.0 mm, without cerci, in female and male nymphs respectively; cerci length subequal to body length. General colouration variable dorsally, ranging from middle to dark brown; young specimens generally paler; legs light brown; with medium brown maculae on dorsal face, uniformly cream-coloured ventrally (Figs. 126–127). Antennae 0.65–0.80 times head width, flagellum with 13–15 segments. Dorsal part of male eyes orange. Labrum (Fig. 20) compact, ca. 2 times wider than long, with smooth anterior emargination; dorsal surface covered medially by numerous, mainly long feathered setae, together with some long simple setae. Mandibles slender with one, sometimes 2, thin setae in middle of outer margin; right mandible (Fig. 27) with outer incisor compact, spoon shape; inner incisor with 2 teeth; prostheca reduced, comprised of a cluster of thin setae; a row of long, thin setae below mola and a cluster of short setae above mola; left mandible (Fig. 34) with outer incisor compact and rounded; inner incisor with 2 teeth inserted transversely, one smaller and pointed, the other large and rounded, prostheca small with a cluster of small setae; no setae below mola. Maxillae slender, with a well developed canine, 2 indented dentisetae and 3 long inner setae apically and a bunch of long simple setae at crown; inner margin at base of lacinia with one long feathered seta dorsally and a row of 4–5 thin feathered setae ventrally (Fig. 42); maxillary palp reduced to a single simple seta. Hypopharynx (Fig. 47) with superlinguae angular laterally, a row of long feathered setae at apex. Submentum moderately developed laterally; glossae and paraglossae partially fused; paraglossae larger than glossae; labial palp 3-segmented, segments 1 and 2 subequal in length, segment 2 slightly wider distally, segment 3 small and rounded, ca. 1.5 times as long as wide at base (Fig. 50). Prothorax with 6 rounded tubercles on dorsal surface; mesothorax embossed, without distinct tubercles. Forefemur (Fig. 61) moderately dilated, ca. 2 times longer than wide; outer margin covered by stout and long setae, meeting a transverse row of stout, relatively short setae (Fig. 62) across dorsal face; a submarginal row of stout and short setae, the same scattered over dorsal face; inner margin with a long row of long and thin setae almost reaching articulation with tibia. Middle and hind femora similar, slightly more slender, ca. 2.2– 2.3 times longer than wide; dorsal and inner margins with a row of long and stout setae, without transverse row. Tibia with a row of long and stout setae on inner margin, and a row of long and thin setae on outer margin. Tarsal claw hooked, bearing 4–6 blunt teeth medially and 2 pointed teeth subapically; apex of claw with two rows of small setae laterally. Abdominal terga with a well developed median tubercle on segments I–VIII, more developed on segment IX and absent on segment X (Fig. 128). Posterolateral projections weakly developed on segments II–V, well marked on segments VI–IX (Fig. 127). Lateral margins of terga with both thin and stout short setae. Gills (Figs. 87–90) on abdominal segments II–V. Gill II with dorsal lamella operculate, oval and with entire margin; gills III–IV with dorsal lamella incised medially; gill V entire; ventral lobe flabellate, well developed and purple on gills II–IV. Cerci with stout setae shorter than length of corresponding segment. Winged stages unknown Diagnosis. T. jacobusi is easily separated from T. insignis, T. tuberculatus and T. kodai by the absence of abdominal gills on segment VI, by the dissimilar teeth of the inner incisor of the left mandible and by the forefemora dilated and with a transverse row of setae. Etymology. This species is named after Dr Luke M. Jacobus (Columbus, Indiana, USA) to acknowledge his major contributions on Oriental Ephemerelloidea and for his constant support during this research.Published as part of Sartori, Michel, Peters, Janice G. & Hubbard, Michael D., 2008, A revision of Oriental Teloganodidae (Insecta, Ephemeroptera, Ephemerelloidea), pp. 1-51 in Zootaxa 1957 (1) on pages 20-21, DOI: 10.11646/zootaxa.1957.1.1, http://zenodo.org/record/524113

    Novel insights on microbiome dynamics during a gill disease outbreak in farmed rainbow trout (Oncorhynchus mykiss)

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    The generic term “Gill disease” refers to a wide range of disorders that affect the gills and severely impact salmonid aquaculture systems worldwide. In rainbow trout freshwater aquaculture, various etiological agents causing gill diseases have been described, particularly Flavobacterium and Amoeba species, but research studies suggest a more complex and multifactorial aetiology. Here, a cohort of rainbow trout affected by gill disease is monitored both through standard laboratory techniques and 16S rRNA Next-Generation Sequencing (NGS) analysis during a natural disease outbreak and subsequent antibiotic treatment with Oxytetracycline. NGS results show a clear clustering of the samples between pre- and post-treatment based on the microbial community of the gills. Interestingly, the three main pathogenic bacteria species in rainbow trout (Yersinia ruckeri, Flavobacterium psychrophilum, and Flavobacterium branchiophilum) appear to be weak descriptors of the diversity between pre-treatment and post-treatment groups. In this study, the dynamics of the gill microbiome during the outbreak and subsequent treatment are far more complex than previously reported in the literature, and environmental factors seem of the utmost importance in determining gill disease. These findings present a potential novel perspective on the diagnosis and management of gill diseases, showing the limitations of conventional laboratory methodologies in elucidating the complexity of this disease in rainbow trout. To the authors’ knowledge, this work is the first to describe the microbiome of rainbow trout gills during a natural outbreak and subsequent antibiotic treatment. The results of this study suggest that NGS can play a critical role in the analysis and comprehension of gill pathology. Using NGS in future research is highly recommended to gain deeper insights into such diseases correlating gill’s microbiome with other possible cofactors and establish strong prevention guidelines
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