52,049 research outputs found
Schooling and education.
No full textSchooling and education by Giles R. Wright with Howard L. Green and Lee R. Parks. Number 4 in the New Jersey Ethnic Life Series. Published by New Jersey Historical Commission
Electrophysiological Study on the Effects of Leptin in Rat Dorsal Motor Nucleus of the Vagus
No full textImmunoreactivity of leptin receptor (Ob-R) has been detected in rat dorsal motor nucleus of the vagus (DMNV). Here, we confirmed the presence of Ob-R immunoreactivity on retrograde-labeled parasympathetic preganglionic neurons in the DMNV of neonatal rats. The present study investigated the effects of leptin on DMNV neurons, including parasympathetic preganglionic neurons, by using whole cell patch-clamp recording technique in brain stem slices of neonatal rats. Leptin (30-300 nM) induced membrane depolarization and hyperpolarization, respectively, in 14 and 15 out of 80 DMNV neurons tested. Both leptin-induced inward and outward currents persisted in the presence of TTX , indicating that leptin affected DNMV neurons postsynapticafly. The current-voltage (I-V) curve of leptin- induced inward currents is characterized by negative slope conductance and has an average reversal potential of -90 +/- 3 mV. The reversal potential of the leptin-induced inward current was shifted to a more positive potential level in a high-potassium medium. These results indicate that a decrease in potassium conductance is likely the main ionic mechanism underlying the leptin-induced depolarization. On the other hand, the I-V curve of leptin-induced outward currents is characterized by positive slope conductance and has an average reversal potential of -88 +/- 3 mV, suggesting that an increase in potassium conductance may underlie leptin-induced hyperpolarization. Most of the leptin-responsive DMNV neurons were identified as being parasympathetic preganglionic neurons. These results suggest that the DMNV is one of the central target sites of leptin, and leptin can regulate parasympathetic outflow from the DMNV by directly acting on the parasympathetic preganglionic neurons of the DMNV
Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants
No full textYves S. Y. Hsieh, Brendan L. Wilkinson, Mitchell R. O, Connell, Joel P. Mackay, Jacqueline M. Matthews, and Richard J. Payn
Post-radiation Pap smear for Chinese patients with cervical cancer: a ten-year follow-up
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C.
No full textDE MAIESTATE / PRAESIDE M. JACOBO THOMASIO, MORALIS PHILOSOPH. P. P., PUBLICE DISPUTABIT JOHANNES DUNTE, R. L. AUTHOR & RESPON: AD DIEM 9. SEPTEMBR. H L. Q. C.
De Maiestate / Praeside M. Jacobo Thomasio, Moralis Philosoph. P. P., publice disputabit Johannes Dunte, R. L. Author & Respon: ad diem 9. Septembr. H L. Q. C. (1)
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Isolation and structural elucidation by 2D NMR of planteose, a major oligosaccharide in the mucilage of chia (Salvia hispanica L.) seeds
No full textAbstract not availableXiaohui Xing, Yves S.Y. Hsieh, Kuok Yap, Main E. Ang, Jelle Lahnstein, Matthew R. Tucker, Rachel A. Burton, Vincent Bulone
Direct observation of spin-polarized surface states in the parent compound of a topological insulator using spin- and angle-resolved photoemission spectroscopy in a Mott-polarimetry mode
Get PDFWe report high-resolution spin-resolved photoemission spectroscopy (spin-ARPES) measurements on the parent compound Sb of the recently discovered three-dimensional topological insulator Bi1−xSbx (Hsieh et al 2008 Nature 452 970, Hsieh et al 2009 Science 323 919). By modulating the incident photon energy, we are able to map both the bulk and the (111) surface band structure, from which we directly demonstrate that the surface bands are spin polarized by the spin–orbit interaction and connect the bulk valence and conduction bands in a topologically non-trivial way. A unique asymmetric Dirac surface state gives rise to a k-splitting of its spin-polarized electronic channels. These results complement our previously published works on this class of materials and re-confirm our discovery of topological insulator states in the Bi₁₋ₓSbₓ series
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