46,243 research outputs found

    The Gaia-ESO Survey: the most metal-poor stars in the Galactic bulge

    No full text
    Howes, L. M. et al.-- Full list of authors: Howes, L. M.; Asplund, M.; Casey, A. R.; Keller, S. C.; Yong, D.; Gilmore, G.; Lind, K.; Worley, C.; Bessell, M. S.; Casagrande, L.; Marino, A. F.; Nataf, D. M.; Owen, C. I.; Da Costa, G. S.; Schmidt, B. P.; Tisserand, P.; Randich, S.; Feltzing, S.; Vallenari, A.; Allende Prieto, C.; Bensby, T.; Flaccomio, E.; Korn, A. J.; Pancino, E.; Recio-Blanco, A.; Smiljanic, R.; Bergemann, M.; Costado, M. T.; Damiani, F.; Heiter, U.; Hill, V.; Hourihane, A.; Jofré, P.; Lardo, C.; de Laverny, P.; Magrini, L.; Maiorca, E.; Masseron, T.; Morbidelli, L.; Sacco, G. G.; Minniti, D.; Zoccali, M.We present the first results of the EMBLA survey (Extremely Metal-poor BuLge stars with AAOmega), aimed at finding metal-poor stars in the Milky Way bulge, where the oldest stars should now preferentially reside. EMBLA utilizes SkyMapper photometry to pre-select metal-poor candidates, which are subsequently confirmed using AAOmega spectroscopy. We describe the discovery and analysis of four bulge giants with -2.72 ≤ [Fe/H] ≤ -2.48, the lowest metallicity bulge stars studied with high-resolution spectroscopy to date. Using FLAMES/UVES spectra through the Gaia-ESO Survey we have derived abundances of twelve elements. Given the uncertainties, we find a chemical similarity between these bulge stars and halo stars of the same metallicity, although the abundance scatter may be larger, with some of the stars showing unusual [α/Fe] ratios. © 2014 The Authors.We greatly acknowledge generous funding from the Australian Research Council (grants FL110100012 and DP120101237). TB was funded by grant no. 621-2009- 3911 from The Swedish Research Council. Support from the Swedish National Space Board is acknowledged. Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under programme ID 188.B-3002. This work was partly supported by the European Union FP7 programme through ERC grant number 320360 and by the Leverhulme Trust through grant RPG-2012-541. We acknowledge the support from INAF and Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR) in the form of the grant ‘Premiale VLT 2012’. The results presented here benefit from discussions held during the Gaia-ESO workshops and conferences supported by the ESF (European Science Foundation) through the GREAT Research Network Programme. MZ acknowledges support from Fondecyt Regular 1110393, the BASAL CATA PFB-06 and by the Chilean Ministry for the Economy, Development, and Tourism's Programa Iniciativa Científica Milenio through grant IC12009, awarded to the Millennium Institute of Astrophysics.Peer reviewe

    Long-term growth in vitro of isolated, fully differentiated neurones from the central nervous system of an adult insect

    No full text
    A method is described for the isolation and growth in vitro of fully differentiated neurones from the thoracic ganglia of adult cockroaches. The presence of insect blood in the culture system is shown to promote growth. The morphology of the growing neurones and the plasticity of the branching processes are described and growth rates are measured. Using a fluorescent Ca2+ indicator dye, changes of intracellular calcium levels in the growing neurones in response to K+ depolarization have been measured. The results, indicating the presence of voltage-dependent Ca2+ channels on neuronal processes in vitro, show that neurones can be maintained in a functional state for several weeks by this technique. Such preparations could prove useful for studying a variety of physiological and pharmacological properties of neurones, including the mechanisms controlling growth, synapse formation and neuronal interactions with other cell types. <br/

    KESESUAIAN PERAWATAN ORTODONTIK BERDASARKAN INDEKS BOLTON, PONT, DAN HOWES YANG DILAKUKAN DI RSGM FKG UNHAS MAKASSAR

    No full text
    2014GEMELLA NUR ILLAHI. Kesesuaian Perawatan Ortodontik Berdasarkan \ud Indeks Bolton, Pont, dan Howes yang Dilakukan Di RSGM FKG Unhas \ud MakassarDibimbing oleh Prof.drg.H. Mansjur Nasir,Ph.D \ud Tujuan : penelitian ini bertujuan untuk mengetahui kesesuaian perawatan ortodontik \ud berdasarkan indeks Bolton, Pont dan Howes di RSGM FKG Unhas \ud Materi dan metode : jenis penelitian ini ialah observasional analitik dengan desain \ud cross sectional. Sampel yang digunakan adalah 100 buah model gigi beserta buku \ud pembicaraan model yang terdiri dari 50 pasang klas I Angle dan 50 pasang klas II \ud Angle. Dilakukan pengukuran model gigi dengan m enggunakan penggaris dan \ud jangka s orong, kemudian hasi lnya dimasu kkan ke dalam rumus Pont, Howes dan \ud Bolton untuk menentukan rencana perawatan yang akan dilakukan . Waktu penelitian \ud dimulai pada Maret sampai Mei 2014. \ud Hasil dan Kesimpulan : (1). Prosentase kesesuaian perawatan berdasarkan indeks \ud Howes dengan Pont untuk maloklusi klas I Angl e diperoleh sebesar 58% sesuai dan \ud 42% tidak sesuai. Untuk maloklusi klas II Angle diperoleh 62 % sesuai dan 38 % \ud t idak sesuai .(2). Prosentase kesesuaian perawatan berdasarkan i indeks Howes dengan \ud Bolton untuk maloklusi klas I Angle diperoleh sebesar 4% sesuai dan 96% tidak \ud sesuai. Untuk maloklusi klas II Ang le 0% sesuai dan 100 % tidak \ud sesuai. (3). Prosentase kesesuaian perawatan berdasarkan indeks Pont dengan Bolton \ud untuk maloklusi klas I Angle dan klas II Angle diperoleh sebesar 22% sesuai dan 78% \ud tidak sesuai. (4). Diperoleh nilai p < 0.05 pada kesesuaian dan ketidaksesuaian \ud perawatan untuk maloklusi klas I Angle dan klas II Angle \ud \ud Kata Kunci : Kesesuaian perawatan, Howes, Pont, Bolton

    Settling of finite-size particles in isotropically forced, homogeneous turbulence: interface-resolved simulations

    No full text
    We have simulated the gravity-induced settling of finite-size particles in a turbulent background flow which is forced in a statistically-stationary fashion. The simulations are accurately resolving the solid-fluid interface with the aid of an immersed boundary technique [1]. The parameters of the simulation are (apart from background turbulence) identical to those of reference [2], where particle clustering was observed at a Galileo number of 178 and a solid volume fraction of 0.005. In the present case, it is found that a relative turbulence intensity of 0.24 leads to the disappearance of the clusters; as a consequence, the increase in average particle settling velocity found in [2] also vanishes. [1] M. Uhlmann. An immersed boundary method with direct forcing for the simulation of particulate flows. J. Comput. Phys., 209(2):448–476, 2005. [2] M. Uhlmann and T. Doychev. Sedimentation of a dilute suspension of rigid spheres at intermediate Galileo numbers: the effect of clustering upon the particle motion. J. Fluid Mech., 752:310–348, 2014

    Reduction in Arterial Stiffness Index (SI) in Response to Combination Antioxidant Therapy

    No full text
    Antioxidants reduce arterial stiffness, but the effects previously reported are weak. A systematic review of the antioxidants vitamin E, vitamin C, vitamin A, and beta-carotenes (the most commonly studied antioxidants) on pulse wave velocity (PWV) found an effect size of only &minus;0.20 (approximately &minus;16 m/s or &minus;2.5%). Studies in rats of the potent pro-oxidant substance acetaldehyde have shown that combinations of sulfur-containing antioxidants, including thiamine and l-cysteine, with ascorbic acid potently protect against oxidative-stress-mediated mortality. The effects of these combinations of oxidants on PWV have not been studied. The present study evaluated the effects of 2 weeks of therapy with a combination of sulfur-containing antioxidants (cysteine, thiamine, and pyridoxine) in combination with ascorbic acid on stiffness index (SI), a measure of arterial stiffness that is strongly correlated with PWV, using a Pulse Trace recorder in a diverse group of 78 volunteers. SI fell by &minus;1.7 m/s relative to placebo (95% confidence intervals &minus;0.6 to &minus;2.7 m/s), a reduction of &minus;19% (95% confidence intervals &minus;9% to &minus;31%). The Glass effect size was 1.4, indicating a very strong treatment effect which was substantially greater than the effect size found in previous studies of antioxidants. PWV reduction was correlated significantly with increasing age. Further studies of similar antioxidant combinations are required to determine whether they are of value in the treatment or prevention of cardiovascular disease

    Dopaminergic basis of salience dysregulation in psychosis

    No full text
    Disrupted salience processing is proposed as central in linking dysregulated dopamine function with psychotic symptoms. Several strands of evidence are now converging in support of this model. Animal studies show that midbrain dopamine neurons are activated by unexpected salient events. In psychotic patients, neurochemical studies have confirmed subcortical striatal dysregulation of dopaminergic neurotransmission, whereas functional magnetic resonance imaging (fMRI) studies of salience tasks have located alterations in prefrontal and striatal dopaminergic projection fields. At the clinical level, this may account for the altered sense of meaning and significance that predates the onset of psychosis. This review draws these different strands of evidence together in support of an emerging understanding of how dopamine dysregulation may lead to aberrant salience and psychotic symptoms. © 2013 Elsevier Ltd

    Mesophilic-hydrothermal-thermophilic (M-H-T) digestion of green corn straw

    No full text
    Mesophilic-hydrothermal (80-160 degrees C, 30 min)-thermophilic (M-H-T) digestion and control tests of mesophilic (M), thermophilic (T), hydrothermal-mesophilic (H-M), and mesophilic-thermophilic digestion (M-T) of green corn straw were conducted for a 20-day fermentation period. The results indicate that M-H-T is an efficient method to improve methane production. A maximum methane yield of 371.74 mL/g volatile solid was obtained by the M (3 days)-H (140 degrees C)-T (17 days) process, which was 20.44%, 16.55%, 31.44%, and 14.31% higher than the yields of the M, T, 140-M, and M-T processes. The enhanced methane production was attributed to (1) the improved hemicellulose degradation and lignin disorganization; (2) prevention of the degradation of soluble sugar, easily hydrolyzed hemicellulose and cellulose into furfural and methylfurfural; and (3) lack of formation of Maillard reaction products during initial hydrothermal treatment. (C) 2015 Elsevier Ltd. All rights reserved

    Using conversation topics for predicting therapy outcomes in schizophrenia.

    No full text
    This article is available from http://www.la-press.com. © the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license.Previous research shows that aspects of doctor-patient communication in therapy can predict patient symptoms, satisfaction and future adherence to treatment (a significant problem with conditions such as schizophrenia). However, automatic prediction has so far shown success only when based on low-level lexical features, and it is unclear how well these can generalize to new data, or whether their effectiveness is due to their capturing aspects of style, structure or content. Here, we examine the use of topic as a higher-level measure of content, more likely to generalize and to have more explanatory power. Investigations show that while topics predict some important factors such as patient satisfaction and ratings of therapy quality, they lack the full predictive power of lower-level features. For some factors, unsupervised methods produce models comparable to manual annotation

    Dr. Glendon Swarthout

    No full text
    Hosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness

    Women's Institute Education Program Awarded Dr. H. M. Tory Memorial

    No full text
    Newspaper Article - 'Women's Institute Education Program Awarded Dr. H. M. Tory Memorial' - In recognition of their program of adult education.AWI CollectionDIRECT AVI MEETING— With the the theme of " Progress to Peace", more t h a n 365 members of the Alberta WI are meeting this week at Convocation Hall, University of Alberta. Platform directors include from left to right, Mrs. R. D. Prendergast, secretary; Mrs. F. S. Lefsrud of Viking, president and Mrs. T. H. Howes of Millet, vice- president. omen s Institute Education Program Awarded Dr. H. M. Tory Memorial I n recognition of their pro­gram of adult education the Federated Women's Institutes have been awarded the Henry Marshall Tory award. This was announced Tuesday afternoon to members of the Al­berta Women's Institute, meet­ing at Convocation Hall, Univ­ersity of Alberta, by Mrs. J. W. Adams of Ethelton, Sask., na­tional president. The award, given each year by the Canadian Association of Adult Education, is in memory of the late Dr. H. M. Tory, first president of the University of Alberta. '' We women owe a debt to democracy," said Mrs. Adams, addressing more than 365 dele­g a t e s attending the week's con­vention. " Democracy needs good citizenship. It is a way of life and is always in* progress." WI AS PIONEER The speaker maintained that the WI has led the way in adult education and reported on nine provincial conventions and pre­sented highlights of the activi­ties of various provinces. She suggested that a national con­vention and a national office is needed. Mrs. Adams pointed out that all the other WI branches are linked with the government, ex­cept the Alberta WI. " Our or­ganization has a complex and growing program. Professional assistance is needed." ' " Coming together is begin­ning; thinking together is unity; planning together is progress; working together is success." Later, Mrs. Adams outlined the activities of the internation­al ACWW which has been ac­corded a membership in the. United Nations, thus carrying a challenge to the women on the provincial, national and interna­tional levels. " Only by sharing can we raise the standard of living of the world through the education of women." PLANT TREES A highlight of the afternoon session was the planting of the three trees in front, and to the right, of the Agricultural Build­ing. Miss Isobel Noble of Wit-chita, Kans. planted an ever­green tree dedicated to the past, as first president of the Alber­ta WI. Mrs. S. Lefsrud, planted a black ash on the east side of the building, to the present. A Manchurian elm, to the future, was planted by Mrs. L. Dunne of Turin, as president of the Girls' Clubs. The trees were accepted by Dr. O. S. Longman, deputy minister of agriculture, for the province; Dr. A. G. McCalla, head of the department of agriculture, for the university; and Mr. J. W. Madille, president of the Agri­cultural Association, for the as­sociation. The service was conducted by Mrs. T. H. Howes of Millet, and Mrs. H. Moonen, convener of the standing committee of agriculture and Canadian In­dustries. CONVENTION THEME With the theme of " Progress to Peace," the convention offi­cially opened Tuesday morning with greetings from Mrs. J. P. White, president of the Ed­monton WI, welcoming the dele­gates. She presented the con­vention with a floral piece — a gold metal figure of the num­ber " 50" surrounded by yellow daisies and iris to mark Al­berta's Jubilee year. Mrs. R. J. Jorgenson, depart­ment of health, brought greet­ings from the province, Dr Andrew Stewart from the uni­versity and Alderman Laurette Douglas from the city. Mrs. G R. Carnihe replied to all greet­ings. Reports were heard from Mrs. S. Lefsrud, president, Mrs. T. H, Howes, vice- president and Mrs. R. W. Prendergast, secretary, when it was announced that there are 37 constituencies, 284 branches, and 5,464 members in the Alberta WI. Publicity re­ports were heard from Mrs. W. Ockley of Calgary, Mrs. J. A. Campbell and Mrs. Howes. Mrs. Howes, a long- time work­er in the WI, was presented with a life membership pin. Mrs. R. Styles, in discussing " objectionable literature" an­nounced that there are 90 mil­lion types of comics published. Mrs. R. Moore of the Ed­monton Public Library, told the women what the library could do to conteract this. " We must bring books to children, and one of the best ways to do this is to set up regional libraries in all the coummunities." Mrs. V. G. McDonald out­lined services offered by the extension service department of agriculture, when she announc­ed that there are 17 home eco­nomic districts. In m u s i c a l entertainment which has been p r o v i d ed between sessions were piano solos by Mrs. S. Lefsrud, vocal solos by Miss Jeanette Mac- Donald and Miss R. Isaac, and j Highland Dancing by Sare LeeJ Holden
    corecore