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Multiple valency and assay amplification
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
Bead-based cellular analysis, sorting and multiplexing
Get PDFFunctionalized cross-linked polystyrene microspheres were synthesized, fluorescently labelled and delivered into cells to function as cellular tags and probes (see figure). This allowed the effective delivery of foreign materials into intact mammalian cells, without the need for delicate procedures such as micro-injection, and did not disrupt cell physiology
Bioprospecting of seahorse traded as traditional medicine : its nutritional values, antioxidation and anti-microbial activities
Get PDFSea horses are not well bioprospected based on scientific data though they are traded around the world for use as traditional medicines and aquarium fishes. Asian countries, including Malaysia are heavily involved in this trade which resulted in approximately 20 million sea horses are collected from the wild annually (Vincent, 1996). Sea horses are thought to resolve an extremely wide range of health problems despite the lacking of scientific data on nutritional
value and active ingredients of the product. The present study conducted to analyse the nutritional values, total polyphenol content (TPC), anti-oxidation and antimicrobial activities of seahorse product available in the local market to support the alleged health benefits. Moisture, crude lipid, crude protein and crude ash were determined using standard methods (AOAC 1990). The TPC was assessed by the Folin-Ciocalteu's method, while the anti-oxidative activities were determined by two different methods; scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals and ferric reducing ability plasma (FRAP) assays. The antimicrobial
properties of Hippocampus barbouri extracts were evaluated using disc diffusion method. The crude protein, crude lipid, ash and moisture contents (% dry weight) ranged from 58 - 69%, 0.6 - 5.2%, 18.7 - 26.8% and 14.6 - 19.0%, respectively. The control sample (live sea horses) showed significantly higher (P<O.OS) protein than the dried product. Male sea horses tend to have low content of lipid but high in ash compared to the females. Factors such as freshness and size of the seahorses may influence the proximate composition. The TPC content extracts of H. barbouriranged from 2.99 to 5.00 mg GAEjg. The ability to reduce DPPH was strongest in
ethanol extract and lowest in ethyl acetate extract. Contradictory, the antioxidant property of H. barbouri in ethanol extracts are much lower than in ethyl acetate and methanol extracts. The values of TPC, DPPH and FRAP assays showed the existence of a significant negative relationship between DPPH and FRAP assays (r = 0.909, p<O.Ol). Only male ethyl acetate extract of H. barbouri showed anti-microbial activity against both C aureus and S. aureus. These findings indicated that seahorse, H. barbour; is a potential source of natural anti-oxidant and possess some anti-microbial activites against the harmful bacteria strain. The results
obtained from the present study are important in the effort to conserve the species and promote seahorse aquaculture
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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