40 research outputs found
Industry-sponsored economic studies in oncology vs studies sponsored by nonprofit organisations
No full textThe purpose of this analysis of health economic studies in the field of oncology was to investigate among sponsored studies whether any relationship could be established between the type of sponsorship and (1) type of economic analysis, (2) health technology assessed, (3) sensitivity analysis performed, (4) publication status, and (5) qualitative conclusions about costs. The Health Economic Evaluations Database (HEED, version 1995-2000) was searched on the basis of oncological ICD-9 codes, sponsorship, and comparative studies. This search yielded a total of 150 eligible articles. Their evaluations were prepared independently by two investigators, on the basis of specific criteria. When evaluators disagreed, a third investigator provided a deciding evaluation. There was no statistically significant relationship between the type of sponsorship and sensitivity analysis performed (P = 0.29) or publication status (P = 0.08). However, we found a significant relationship between the types of sponsorship and of economic analysis (P = 0.004), the health technology assessed (P < 0.0001), and qualitative cost assessment (P = 0.002). Studies with industrial sponsorship were 2.56 (99% lower confidence interval (CI) = 1.28) times more likely to involve cost-minimisation analyses, were 0.04 (99% higher CI = 0.39) times less likely to investigate diagnostic screening methods, and were 1.86 (99% lower CI = 1.21) times more likely to reach positive qualitative conclusions about costs than studies supported by nonprofit organisations. In conclusion, our results suggest that there is a greater probability that industry-sponsored economic studies in the field ofi oncology tend to be cost-minimisation analyses, to investigate less likely diagnostic screening methods, and to draw positive qualitative conclusions about costs, as compared to studies supported by nonprofit organisations.Vo
Make MOOCs count for higher education: Approaches to awarding ECTS Credits for learning in open online courses
No full textMOOCs provided by Higher Education Institutions (HEIs) have the potential to open up education to a wider audience. By implementing appropriate quality assurance measures, they could also provide a first creditable step into the formal higher education system. Exploring the potential of credentialization and recognition of MOOCs was a major pillar of the INTEGRAL²-project (“Integration and Participation of Refugees in the Context of Digital Teaching and Learning Scenarios”) of Lübeck University of Applied Sciences, RWTH Aachen University and Kiron Open Higher Education. The partners explored possible combinations of the openness of MOOC-based learning with quality assurance and examination approaches that abide to standards of the European Higher Education Area. Regarding quality assurance measures, Kiron has repurposed and adapted tools developed through the Bologna Process in order to explore new pathways to the recognition of prior learning. A core element are MOOC booklets (MOOklets) that connect and display all quality information needed for recognition in a comparable, standardized way. As the university partners identified the existing exams within MOOCs to be the most critical part in order to award legitimate credit points, the partners followed two different approaches: Module-based competence assessment (on- and offline) and MOOC-based examinations (offline). Lübeck University of Applied Sciences tested a procedure to verify learning outcomes by written and oral examinations whilst RWTH Aachen University targeted a more traditional examination approach with written and e-exams that can be taken simultaneously at different offline locations. In the follow-up project INTEGRAL+, the partners will focus on establishing a German examination network for e-assessment of MOOC-based learning. Both efforts in the field of a firm examinations and the endorsement of recognition processes of all existing and future university partners within the Kiron network can lead to simplified admission process and can be key enablers of a successful integration via education
Drug retention by inline filters – Effect of positively charged polyethersulfone filter membranes on drug solutions with low concentration
No full textDiggiCORE - White Paper
No full textThe goal of the DiggiCORE (Digging into Connected REpositories) project was to aggregate, at the level of both metadata and content, a vast set of research publications, from institutional repositories, archives (green OA route) and journals (gold OA route) worldwide, and provide novel tools for automatic enrichment of this content with relationships (relatedness, citations). The aggregated data with these relationships were used in turn to generate and publicly expose large and openly available networks of Open Access publications. These networks together with the actual fulltext content can be then analysed using natural language processing and social network analysis methods to identify patterns in the behaviour of research communities, to recognise trends in research disciplines, to learn new insights about the citation behaviours of researchers, to discover new features that distinguish papers with high impact, etc.
To enable the analysis, the DiggiCORE project has developed a software infrastructure, building on top of the CORE system, which provides access to Open Access research outputs acquired by harvesting, cleaning, integrating and processing information from a very large and fast growing collection of millions of research publications. The DiggiCORE project has built tools that enable access to the raw textual content intended for machine processing and the extracted and generated networks (citation network, article relatedness, author citation network) to the public via a set of web services and also as a downloadable dataset, thus creating a single access point for Open Access research
outputs
Industry-sponsored economic studies in critical and intensive care versus studies sponsored by nonprofit organizations
No full textThe purpose of this analysis of health economic studies in the field of intensive and critical care was to investigate whether any relationship could be established between type of sponsorship and (1) type of economic analysis, (2) health technology assessed, (3) sensitivity analysis performed, (4) publication status, and (5) qualitative cost assessment. Using the terms critical careor intensive care, all health economics publications in the field of critical and intensive care were identified in the Health Economic Evaluations Database (HEED, Version 1995-2001) on the basis of sponsorship and comparative studies. This search yielded a total of 42 eligible articles. Their evaluations were prepared independently by 2 investigators on the basis of specific criteria. When evaluators disagreed, a third investigator provided a deciding evaluation. There was no statistically demonstrable relationship between types of sponsorship and sensitivity analysis performed, publication status, types of economic analysis, or qualitative cost assessment.Vo
MAI 1701 : DEUX PRINCES EN BOURGOGNE
No full textInternational audienceThe starting point for this study is the visit of two grandsons of the Sun King Louis XIV to Burgundy and their stay in Beaune in April 1701. These forerunners of wine tourism had a particular fondness for Burgundy, as a short detour to Volnay shows. The author reveals the details of this well-documented journey, which the Mercure Galant accurately depicts with its Bacchanalian decorations, particularly the wine fountains. These descriptions provide us with one of the first mentions of the Meursault vintage. Why on this occasion, and why should this wine flow from a wine fountain? To understand what happened in 1701 from Mâcon to Auxerre, via Beaune, Dijon and even Talant, the author invites us to follow this little-studied phenomenon, wine fountains through history. You will discover which wines flowed in the land of Cockaigne, at the tables of princes and in the streets, in front of the palaces of the Grand Dukes of the West, on the occasion of the coronation of the Emperors of the Holy Roman Empire or during the reign of the Sun King. This book reveals the role of wine fountains in communication between a city and the authorities, but also between different groups in a hierarchical society. It also shows how the cities on the princes' itinerary in 1701 competed with each other in their imagination and used wine as a communication tool in very different ways, creating extravagant and costly decorations to showcase their emphatic praise of the princes.Le point de départ de cette étude est la visite de deux petits-fils du Roi Soleil Louis XIV en Bourgogne et leur séjour à Beaune en avril 1701. Ces précurseurs de l’œnotourisme ont une sensibilité particulière pour le bourgogne, un petit détour à Volnay en fait preuve. L'auteur nous dévoile les détails de ce voyage bien documenté, dont le Mercure Galant dépeint avec précision les décorations sur le thème bacchique, notamment les fontaines de vin. Or, ces descriptions nous donnent l’une des premières mentions du cru de Meursault. Pourquoi en cette occasion, et pourquoi ce vin doit-il couler d'une fontaine à vin ? Pour comprendre ce qui se passe en 1701 de Mâcon à Auxerre, en passant par Beaune, Dijon et même Talant, l’auteur nous invite à suivre ce phénomène peu étudié, les fontaines de vin à travers l'histoire. Vous découvrirez ainsi quels vins coulaient au pays de Cocagne, à la table des princes et dans les rues, devant les palais des Grands Ducs d’Occident, à l'occasion du couronnement des Empereurs du Saint-Empire ou sous le règne du Roi-Soleil. Ce livre révèle la fonction des fontaines de vin dans la communication entre une ville et les autorités, mais aussi entre les différents groupes d'une société hiérarchisée. Il montre aussi comment les villes placées sur le parcours des princes, en 1701, ont rivalisé d’imagination et utilisé de manières très différentes le vin comme outil de communication, réalisant d’extravagants et coûteux décors pour mettre en scène leurs emphatiques louanges aux princes
The future of PATLIB centres in a globalized patent world
No full textThe article focuses on the continuing requirement for patent libraries to adapt to the changing global environment in patent information. The drivers of these changes are outlined, including the ever-increasing inputs to, and publications of, the intellectual property offices, especially those in East Asia, allied to the changed priorities of SME users of patent information, from relatively basic information to more sophisticated searches and advice in the business-related environment. The author then reports the current views of the European PATLIB network on their future priorities for services such as database searches, training of IP users, technology transfer advice, and networking with partners who can provide complementary services. Some initiatives within the EPO's policy for cooperation with member states are outlined, such as raising awareness and use of the patent system, patent information, and the exploitation of IP rights, especially amongst educational organisations and institutes and SMEs. The author accordingly argues that it is only through such adaptation that PATLIB centres will be able to provide higher quality, customer-related, added value services in support of innovation that are needed by users.PATLIB future EPO IPO inputs SMEs Searches Training Innovation services Technology transfer Networking Education
Verwendung von Routinedaten der gesetzlichen Krankenkasse in einer Pilotstudie zur Evaluation pharmazeutischer Interventionen im Krankenhaus
No full textSteroid hormone metabolism by cytochrome P450 in the rodent hippocampus in vivo und in vitro
No full textantigen testing in recipients of allogeneic haematopoietic cell transplantation due to administration of parenteral nutrition and fixed combinations of piperacillin‐tazobactam
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