27 research outputs found
Predictive significance of high neutrophil ratio for thrombosis in myeloproliferative neoplasms: JSH-MPN-R18 subanalysis
Citation: Keiki Nagaharu, Eiko Ohya, Yoko Edahiro, Yoshinori Hashimoto, Tomoki Ito, Akihiko Gotoh, Mika Nakamae, Fumihiko Kimura, Michiaki Koike, Keita Kirito, Hideho Wada, Kensuke Usuki, Takayuki Tanaka, Takehiko Mori, Satoshi Wakita, Toshiki I. Saito, Akiko M. Saito, Kazuya Shimoda, Toshiro Kurokawa, Akihiro Tomita, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Katsuto Takenaka, Norio Komatsu, Kohshi Ohishi, Isao Tawara, Yuka Sugimoto, Predictive significance of high neutrophil ratio for thrombosis in myeloproliferative neoplasms: JSH-MPN-R18 subanalysis, Annals of Hematology, 103(9), 3535-3541, 2024-07-22, https://doi.org/10.1007/s00277-024-05898-
A Case of Adrenergic Crisis Caused by Spontaneous Rupture of Cystic Pheochromocytoma
Pheochromocytoma crisis is a life-threatening situation. Herein we report a case of catecholamineinduced crisis caused by the rupture of cystic pheochromocytoma. A 76-year-old man with hypertension was referred to our hospital because of a cystic tumor in the retroperitoneal space adjacent to the aorta, which was suspicious of pheochromocytoma. Two days after admission, lower abdominal pain suddenly appeared, followed by hypertension with systolic pressure of 260mmHg. Computed tomography revealed that the cystic tumor was ruptured spontaneously, leading to diagnosis of pheochromocytoma crisis. His blood pressure was successfully managed by medical treatment and he could recover from crisis. After adequate medical preparation by an α-adrenergic blocker, the tumor was successfully removed by laparoscopy, though the adhesion around the tumor was severe. To our knowledge adrenergic crisis caused by spontaneous rupture of cystic pheochromocytoma is rare, but we have to keep in mind that cystic pheochromocytoma can cause life-threatening crisis by the release of catecholamine due to rupture
Condyle laterotrusion analysis on Bennetts side shift and centrifuge lateral movements in edentate subjects
Atualmente na odontologia ainda há muita dificuldade na compreensão do movimento de Bennett ou laterotrusão. Devido a questões de inviolabilidade inerentes à característica da articulação temporomandibular não é possível observar diretamente o seu interior, de maneira que a análise da sua dinâmica durante a função torna-se questionável. Assim, o autor trabalhou com imagens e inferências aplicadas numa metodologia utilizada para tal fim. A proposta dessa pesquisa foi a de analisar o comportamento condilar durante os movimentos de lateralidade Centrífuga e de Bennett em pacientes portadores de prótese total. Vinte e dois indivíduos receberam novas próteses totais. O registro maxilomandibular foi realizado com a técnica de Gysi com a plataforma e pua extraoral. Utilizando-se uma pua modificada de forma que esta realizasse dois registros (pua dupla) com o mesmo movimento e, ao invés da cera aplicada sobre a plataforma, o registro foi feito sobre um fino papel carbono aderido a esta com uma fita adesiva dupla face. Através de imagens digitalizadas do articulador e dos registros no carbono foi possível, com a utilização de um programa de tratamento de imagens, arbitrar e testar a posição do eixo vertical de rotação condilar durante a lateralidade centrífuga e de Bennett. Os resultados mostraram uma predominância nos eventos onde o eixo vertical do côndilo posicionou-se na região ântero-lateral e póstero-medial durante a lateralidade de Bennett, porém mostrou uma predominância de eventos localizados na região póstero-medial durante a lateralidade Centrífuga. Houve casos onde o eixo vertical localizou-se exatamente sobre o centro da esfera, o que indica que o paciente durante a lateralidade não promoveu excursão do côndilo de trabalho, realizando um movimento de rotação puro se analisado no plano horizontal. De acordo com a metodologia aplicada nessa pesquisa concluiu-se que o eixo da lateralidade Centrífuga é mais medial que o da lateralidade de Bennett e que a maior parte dos eixos não coincide com aquele sobre o centro da esfera condilar.It has been controversial the understanding of both the Bennetts side shift and Centrifuge lateral movements. Had the inherent questions of TMJ´s inviolability it is not possible to observe its interior directly, thus the analysis of its dynamics during the function becomes questionable. The author worked with images and inferences applied to a methodology used for such end. The proposal of this research was to analyze the behavior of jaw condyle Bennetts side shift and Centrifuge lateral movements in complete denture wearers. Twenty two subjects had new dentures constructed. The mandible tracings were made using the technique of Gysi with an extra oral device with two registration markers. Instead of wax it was applied a fine articulating paper adhered to the platform by a double face adhesive ribbon. Digitalized images from articulator and from articulating papers were set together. It was used a software of treatment of images both to decide and to test the position of the vertical axle of rotation of the jaw during the Bennetts side shift and during Centrifuge lateral movement. The results were a predominance of the events where the vertical axis were located in the backward medial region for the centrifuge lateral movement and were located both in the backward medial and in the forward lateral region for the Bennetts side shift. It had cases where the vertical axle was situated accurately on the center of the condyle sphere, what is supposed to mean that the patient, during the lateral jaw movement did not promote excursion of the working side condyle. In accordance with the methodology applied in this research, the author concluded that the axis of the centrifuge lateral movement is more medial than the one of the Bennetts side shift, and that in the great majority of the events the axis did not met the condyle sphere of the articulator
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Correction: The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium
Correction to: Molecular Psychiatry, published online 2 May 2023 In this article Honami Arai, Irene Bollettini, Rosa Calvo Escalona, Ana Coelho, Federica Colombo, Leila Darwich, Martine Fontaine, Toshikazu Ikuta, Jonathan C. Ipser, Asier Juaneda-Seguí, Hitomi Kitagawa, Gerd Kvale, Mafalda Machado-Sousa, Astrid Morer, Takashi Nakamae, Jin Narumoto, Joseph O’Neill, Sho Okawa, Eva Real, Veit Roessner, Joao R. Sato, Cinto Segalàs, Roseli G. Shavitt, Dick J. Veltman, Kei Yamada were missing from the author list indexed under the ENIGMA-OCD Working Group. Additionally, there was an error regarding Tokiko Yoshida’s name, where the first name and last name were written in the wrong order. The original article has been corrected
Evaluation of the relationship amongst the working groove angulation of artificial teeth and the orientation plane and the vertical rotation axis of mandibular lateral translation in the articulator
Na reabilitação protética, a oclusão e os movimentos mandibulares estão intrinsecamente ligados. A harmonia entre estes dois fatores torna-se indispensável para o sucesso do tratamento. Um dos conceitos sempre abordados na busca deste ideal é a relação entre os sulcos e as cúspides dos dentes com os movimentos mandibulares, onde as segundas devem passar livremente sobre os primeiros durante a movimentação mandibular. Assim, foi proposto avaliar o grau de coincidência da angulação do sulco de trabalho do primeiro molar inferior artificial, quando posicionado no arco, em relação à trajetória descrita pela cúspide mésiopalatina do primeiro molar superior em relação ao eixo de rotação vertical de lateralidade da mandíbula no articulador semi-ajustável. O autor utilizou uma metodologia que permitiu identificar esta trajetória com o auxílio de um programa de editoração gráfica. Foi possível avaliar as imagens digitais de montagens em cera de dentes artificiais em prótese totais inferiores e de seus respectivos planos de orientação posicionados em articulador. Através das imagens, localizou-se o sulco de trabalho do primeiro molar inferior, a trajetória da cúspide mésio-palatina do primeiro molar superior adotando-se o eixo de rotação vertical no centro das esferas condilares, e a perpendicular à tangente ao plano de orientação. Assim, mediu-se o ângulo formado entre a perpendicular à tangente e o sulco de trabalho e o ângulo entre a trajetória do eixo de rotação vertical e o sulco de trabalho. Os resultados mostraram que houve casos onde o sulco de trabalho coincidiu com a perpendicular à tangente do plano de orientação, nos demais casos a angulação apresentou, em média, valores baixos demonstrando que as montagens dos dentes artificiais seguiram os parâmetros adotados no plano de orientação segundo a técnica proposta. Estatisticamente, a distância intercondilar não interferiu nas médias dos ângulos entre o sulco de trabalho e a trajetória do eixo vertical de rotação. Não foi observada a coincidência entre o sulco de trabalho e a trajetória do eixo de rotação vertical, indicando que, durante a reprodução do movimento de lateralidade no articulador, ocorre interferência na excursão da cúspide mésio-palatina do primeiro molar superior.In prosthetic rehabilitation, occlusion and mandibular movements are closely linked. Harmony between these factors is essential for treatment success. One of the main concepts approached when aiming for this goal is the relationship between teeth grooves and cuspids and mandibular movements, where cuspids must not touch grooves during these movements. Therefore, the present study proposes to evaluate the degree of coincidence of the working groove angulation from the artificial mandibular first molar, when positioned on the arch, with the trajectory traced by the mesio-palatal cuspid from the maxillary first molar during mandibular lateral translation determined by the vertical axis rotation in a semi-adjustable articulator. To identify this trajectory, the author utilized a graphical editing program. It was possible to evaluate digital images from artificial teeth mounted on wax for mandibular complete dentures, and their respective orientation planes positioned on the articulator. Through these images, the author located the working groove from the mandibular first molar, the trajectory described by the mesio-palatal cuspid from the maxillary first molar considering the vertical axis rotation at the center of the condilar spheres, and the perpendicular to the tangent of orientation plane. Thus, the angle between the perpendicular to the tangent and working groove and the angle between the trajectory of the vertical axis rotation and the working groove were measured. The results showed some cases where the working groove coincided with the perpendicular to the tangent of the orientation plane. In the remaining cases, the angulation displayed low mean values, illustrating that the mounting of artificial teeth followed the parameters adopted for the orientation plane according to the proposed technique. The distance between condoles did not significantly interfere in the mean values for the angles between the working groove and the trajectory of the vertical axis rotation. The coincidence between the working groove and the trajectory of the vertical axis rotation was not observed, indicating that, during the lateral translation movement in the articulator, there is interference in the trajectory of the maxillary first molar mesio-palatal cuspid
Effect of Trimming Feathers off Abdominal and Crural Tracts of the Hen on Parasitism of Mites.
Incidence of the Parasitism of Chicken Mite Dermanyssus gallinae Parasitizing and Propagating on Chicken Even in the Daytime and Their Life Cycle.
Turnip mosaic potyvirus probably first spread to Eurasian brassica crops from wild orchids about 1000 years ago
Turnip mosaic potyvirus (TuMV) is probably the most widespread and damaging virus that infects cultivated brassicas worldwide. Previous work has indicated that the virus originated in western Eurasia, with all of its closest relatives being viruses of monocotyledonous plants. Here we report that we have identified a sister lineage of TuMV-like potyviruses (TuMV-OM) from European orchids. The isolates of TuMV-OM form a monophyletic sister lineage to the brassica-infecting TuMVs (TuMV-BIs), and are nested within a clade of monocotyledon-infecting viruses. Extensive host-range tests showed that all of the TuMV-OMs are biologically similar to, but distinct from, TuMV-BIs and do not readily infect brassicas. We conclude that it is more likely that TuMV evolved from a TuMV-OM-like ancestor than the reverse. We did Bayesian coalescent analyses using a combination of novel and published sequence data from four TuMV genes [helper component-proteinase protein (HC-Pro), protein 3(P3), nuclear inclusion b protein (NIb), and coat protein (CP)]. Three genes (HC-Pro, P3, and NIb), but not the CP gene, gave results indicating that the TuMV-BI viruses diverged from TuMV-OMs around 1000 years ago. Only 150 years later, the four lineages of the present global population of TuMV-BIs diverged from one another. These dates are congruent with historical records of the spread of agriculture in Western Europe. From about 1200 years ago, there was a warming of the climate, and agriculture and the human population of the region greatly increased. Farming replaced woodlands, fostering viruses and aphid vectors that could invade the crops, which included several brassica cultivars and weeds. Later, starting 500 years ago, inter-continental maritime trade probably spread the TuMV-BIs to the remainder of the world
