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Replication Data for: "How Reliable Is the Market for Technology?"
No full textReplication Data for: "How Reliable Is the Market for Technology?
Replication Data for: How Reliable is the Market for Technology?
No full textReview of Economics and Statistics: Forthcoming
Replication Data for: How Reliable is the Market for Technology?
No full textReview of Economics and Statistics: Forthcoming
Structure of the essential malaria invasion protein RH5 in complex with its erythrocyte receptor and inhibitory antibodies
Full text linkInvasion of host erythrocytes is an essential stage in the life cycle of Plasmodium parasites and in development of the pathology of malaria. The stages of erythrocyte invasion, including initial contact, apical reorientation, junction formation, and active invagination, are directed by the coordinated release of specialised apical organelles and their parasite protein contents. Among these proteins, and central to invasion by all species, are two parasite protein families, the reticulocyte-binding protein homologue (RH) and the erythrocyte-binding like (EBL) proteins, that mediate host-parasite interactions. RH5 from Plasmodium falciparum (PfRH5) is the only member of either family demonstrated to be necessary for erythrocyte invasion in all tested strains, through its interaction with the erythrocyte surface protein basigin. Indeed, antibodies targeting either PfRH5 or basigin can block parasite invasion with high efficiency in vitro, making PfRH5 an excellent candidate for a vaccine to protect against the most deadly form of malaria. Here I present crystal structures of PfRH5 in complex with basigin and with two distinct inhibitory antibodies. This is the first structure of any RH protein, revealing a novel fold in which two three-helical bundles come together to form a kite-like architecture. The two immunoglobulin domains of basigin and the inhibitory antibodies bind to one tip of the kite. These findings provide the first structural insights into erythrocyte binding by the Plasmodium RH protein family and identify novel inhibitory epitopes to guide the design of a new generation of vaccines against the blood-stage parasite
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Challenging Conventions, Building Solidarity: The Future(s) of Critical Marketing
No full textIn this chapter, we will weave a history of marketing theory and practice that permits us to juxtapose mainstream and Critical Marketing scholarship. From this, we unpack core assumptions underwriting Critical Marketing Studies, including ontological denaturalisation, defatalisation, epistemological reflexivity, critical performativity and solidarity building. Our narrative then introduces each chapter in the Companion
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Consumer vulnerability : critical insights from stories, action research and visual culture
Full text linkCritical marketing scholars have been encouraged to consider the experiences of consumers who encounter marketplace exclusion, consumers “whose views are rarely heard by those in positions of power” (Tadajewski, 2010, p. 214). Our focus in this chapter is on consumers experiencing vulnerability. Baker et al. (2005, p. 134) offer the following definition of consumer vulnerability: “[c]onsumer vulnerability is a state of powerlessness that arises from an imbalance in marketplace interactions or from the consumption of marketing messages and products. It occurs when control is not in an individual’s hands, creating a dependence on external factors (e.g. marketers) to create fairness in the marketplace. The actual vulnerability arises from the interaction of individual states, individual characteristics, and external conditions within a context where consumption goals may be hindered and the experience affects personal and social perceptions of self.” Central to Baker et al.’s (2005) definition is the lack of control and power experienced by some consumers, but also that the experience of vulnerability is often heightened due to circumstances beyond the individual’s control (e.g. how other people respond to her/him). This point emphasises the socially constructed and interactive nature of consumer vulnerability. Since the 1990s the importance of consumer vulnerability has been recognised with research exploring its conditions and contexts (Smith and Cooper-Martin, 1997; Gentry et al, 1994; Hill & Stamey, 1990; Ozanne et al, 1998; Morgan et al, 1995; Botti et al, 2008; Schultz et al, 2009; Ozanne & Ozanne, 2011; Cartwright, 2015). This work has been published in a range of outlets, including special issues of Journal of Macromarketing (Hill, 2005) and Journal of Marketing Management (Dunnett, Hamilton and Piacentini, 2016) and an edited collection (Hamilton, Dunnett and Piacentini, 2016). Much of this research stream questions and problematizes experiences of vulnerability within the marketplace
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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