9,751 research outputs found
Implementing the AIFMD: Success or failure? ECMI Commentary No. 34, 28 March 2013
Get PDFThis commentary considers the implementation of the Alternative Investment Fund Managers Directive (AIFMD) by the European Commission. The AIFMD creates an internal market for asset management and as an endeavour to develop market-based finance is an important piece of legislation for the European economy. The author, Mirzha de Manuel Aramendía, considers the implementation of some of the provisions that raised concern among industry participants. He finds that, on balance, a practical and flexible approach to implementation has been followed that should help secure the success of the framework, which at present is still uncertain. The commentary also considers the remuneration guidelines adopted recently by the European Securities and Markets Authority (ESMA). It encourages EU and national authorities to commit to the success of the AIFMD framework, as part of a broader effort to develop capital markets and reduce the historical reliance of the European economy on bank finance
Finger Sequence Learning in Adults Who Stutter
No full textKorzeczek A, Cholin J, Jorschick A, Hewitt M, Sommer M. Finger Sequence Learning in Adults Who Stutter. Frontiers in Psychology. 2020;11: 1543.Originary neurogenic, non-syndromatic stuttering has been linked to a dysfunctional sensorimotor system. Studies have demonstrated that adults who stutter (AWS) perform poorly at speech and finger motor tasks and learning (e.g., Smits-Bandstra et al., 2006b; Namasivayam and van Lieshout, 2008). The high relapse rate after stuttering treatment could be a further hint for deficient motor learning and, in particular, for the limited generalization of the learned technique in daily communication. In this study, we tested generalization of finger sequence skills in AWS using an effector-dependent transfer task after a 24-h retention period. Additionally, we wanted to corroborate previous motor learning results in AWS for practice and retention: 16 AWS and 16 age-, sex-, and education-matched controls performed the task during four test sessions. Our results indicate that generalization performance in AWS was not inferior to that of fluent controls. In addition, we found, contrary to previous results, that AWS showed a steeper learning progress after practice and consolidation compared with controls. We suggest that with sufficient practice and a 24-h consolidation phase, AWS are able to retain the learned performance of tapping a five-item finger sequence as well as fluent controls in terms of speed and accuracy
Neuroscientists Do Not Use Non-invasive Brain Stimulation on Themselves for Neural Enhancement
No full textAutomated TMS hotspot-hunting using a closed loop threshold-based algorithm
No full textBackground: Although neuronavigation is increasingly used for optimizing coil positioning, the inter-session reliability of hotspot location remains unsatisfactory, probably due to the variability of motor evoked potentials (MEPs) and residual investigator bias. Purpose: To increase the reliability and accuracy of hotspot location we introduce a novel automated hotspot-hunting procedure (AHH). Methods: AHH is based on resting motor thresholds (RMTs) instead of MEP amplitudes. By combining robotic coil positioning with a closed loop target search algorithm AHH runs independently from the investigator. AHH first identifies all targets with an RMT below a defined intensity of stimulator output (MEP-positive) and then locates the motor hotspot of a target muscle by measuring RMTs at all identified MEP-positive targets. Results were compared to robotic MEP amplitude TMS mapping (MAM) using a 7 x 7 predefined target grid and suprathreshold intensities and manual hotspot search (MHS). Sequence of stimulation was randomized from pulse to pulse in AHH and MAM. Each procedure was tested in 8 subjects. Results: Inter-session CoG shift was significantly reduced with AHH (1.4 mm (SEM: 0.4)) as compared to MAM (7.0 mm (SEM: 1.8)) (p=0.018) and MHS (9.6 mm (SEM: 2.2)) (p=0.007). No statistical difference was observed between MAM and MHS. RMTs were reliable between sessions. Conclusion: Our method represents the first fully automated, i.e. investigator-independent, TMS hotspot-hunting procedure. Measuring RMTs instead of MEP amplitudes leads to significantly increased accuracy and reliability of CoG locations. Moreover, by assessing thresholds AHH is the first procedure to fulfill the original hotspot definition. (C) 2015 Elsevier Inc. All rights reserved
Manuel Puig: un destino melodramático
Get PDFEl trabajo es un extracto de una larga investigación en los archivos del escritor argentino Manuel Puig, la génesis de su producción y su relación con el campo intelectual internacional. En este extracto se presenta un estudio del uso del melodrama en la producción 'espectacular' del autor y la publcación de un inédito que incluí como primicia en 1996 en la revista Orbis Tertius No. 2, Centro de Teoría y Crítica Literaria, UNLP.The work is an extract of one long recherch in the archives of the Argentine writer Manuel Puig, the genesis of its production and its relation with international the intellectual field. In this extract is analyzed the use of the melodrama in “the spectacular” production of the author. The publication of an unpublished is included , published for the first time by me in 1996 in the Orbis Tertius Nº 2, Centro de Teoría y Crítica Literaria, UNLP.Facultad de Humanidades y Ciencias de la Educació
Letter from Manuel E. Ykari [Ikari] to Wayne M. Collins, May 29, 1953
No full textIn this letter to Mr. Wayne M. Collins, Mr. Manuel E. Ykari [Ikari] explains that he will need to pay Mr. Collins in segments. Mr. Collins is a lawyer in San Francisco.Collection of notes, articles, correspondence, photographs, and term papers collected by Yukio Mochizuki, a student at CSU Dominguez Hills, while researching Japanese American incarceration and Japanese Peruvian internment during World War II
Oral History Interview with Manuel Medrano, June 18, 2015
No full textInterview with Manuel Medrano, an historian and author from Brownsville, Texas. In his interview, Medrano discusses his family background and childhood, education, experiences with discrimination, political activism, and the Chicano movement
Manuel Muñoz, 38th Annual ODU Literary Festival
No full textManuel Muñoz is the author of a novel, What You See in the Dark, as well as two short-story collections, Zigzagger and The Faith Healer of Olive Avenue, which was shortlisted for the Frank O\u27Connor International Short Story Award. His work has appeared in The New York Times, Glimmer Train and Boston Review and has aired on NPR’s “Selected Shorts. The recipient of an O. Henry Prize and a Whiting Writers\u27 Award, Muñoz lives in Tucson, Ariz., where he is an associate professor at the University of Arizona
Manuel Trillo de Leyva. Obra completa 1964-2005
Get PDFDenis Diderot is credited with saying that men of the past have a great advantage over us in that they did not know the weight of Antiquity. Something of that authority from a bygone era permeates much of the figure of Manuel Trillo de Leyva, a key figure in Seville\u27s architecture in the second half of the 20th century, who has been the subject of this recent monograph promoted by the COAS. For students in the late 2000s, shortly after his untimely death, Manuel Trillo was the name of the auditorium at the School of Architecture, a name that professors imbued with a halo of admiration and that gradually revealed itself to be a life of its own, that of the author of several of the city\u27s landmark buildings. The first of these was precisely that same stage, designed as a result of a competition won together with José Garrido when they were still students.A Denis Diderot se le atribuye haber dicho que los hombres del pasado tienen sobre nosotros la gran ventaja de no haber conocido el peso de la Antigüedad. Algo de esa autoridad de un tiempo anterior impregna mucho de la figura de Manuel Trillo de Leyva, clave para la arquitectura sevillana de la segunda mitad del siglo XX, que ha sido objeto de esta reciente monografía impulsada por el COAS. Para el alumnado de finales de la década de los 2000, poco después de su temprano fallecimiento, Manuel Trillo era el nombre del salón de actos de la Escuela de Arquitectura, nombre que los profesores imbuían de un halo de admiración y que poco a poco se desvelaba como una vida propia, la del autor de varios de los edificios señeros de la ciudad. El primero de ellos había sido precisamente ese mismo escenario, diseñado a resultas de un concurso ganado junto con José Garrido cuando aún ocupaban la platea como estudiantes
Manuel Trillo de Leyva. Obra completa 1964-2005
Get PDFDenis Diderot is credited with saying that men of the past have a great advantage over us in that they did not know the weight of Antiquity. Something of that authority from a bygone era permeates much of the figure of Manuel Trillo de Leyva, a key figure in Seville\u27s architecture in the second half of the 20th century, who has been the subject of this recent monograph promoted by the COAS. For students in the late 2000s, shortly after his untimely death, Manuel Trillo was the name of the auditorium at the School of Architecture, a name that professors imbued with a halo of admiration and that gradually revealed itself to be a life of its own, that of the author of several of the city\u27s landmark buildings. The first of these was precisely that same stage, designed as a result of a competition won together with José Garrido when they were still students.A Denis Diderot se le atribuye haber dicho que los hombres del pasado tienen sobre nosotros la gran ventaja de no haber conocido el peso de la Antigüedad. Algo de esa autoridad de un tiempo anterior impregna mucho de la figura de Manuel Trillo de Leyva, clave para la arquitectura sevillana de la segunda mitad del siglo XX, que ha sido objeto de esta reciente monografía impulsada por el COAS. Para el alumnado de finales de la década de los 2000, poco después de su temprano fallecimiento, Manuel Trillo era el nombre del salón de actos de la Escuela de Arquitectura, nombre que los profesores imbuían de un halo de admiración y que poco a poco se desvelaba como una vida propia, la del autor de varios de los edificios señeros de la ciudad. El primero de ellos había sido precisamente ese mismo escenario, diseñado a resultas de un concurso ganado junto con José Garrido cuando aún ocupaban la platea como estudiantes
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