1,720,982 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Identification and characterization of new disease Genes for cardiomyopathies
No full textGesamtdissertationDie arrhythmogene rechtsventrikuläre Kardiomyopathie (ARVC) ist gekennzeichnet
durch einen progressiven Ersatz der rechtsventrikulären Kardiomyozyten durch
Fett- und Bindegewebe. Diese pathologischen Veränderungen können zu
ventrikulären Tachyarrhythmien und zum plötzlichen Herztod führen. Wir konnten
im humanen Plakophilin-2 Gen (PKP2) bei 120 nicht verwandten ARVC Patienten 32
heterozygote Mutationen identifizierten. Plakophilin-2 ist ein essenzieller
Bestandteil des Desmosoms. Die kardialen Desmosomen gewährleisten die
mechanische Stabilität des Herzmuskels und übertragen die Kraft des
kontraktilen Apparates. Zusätzlich können sie an der Signaltransduktion der
Kardiomyozyten teilnehmen. Die Mehrzahl der identifizierten Mutationen führen
zur Insertion von verfrühten Stopp-Kodons. Kardiale Expressionsanalysen von
Herzbiopsien zeigen sowohl das Fehlen eines trunkierten Proteins als auch eine
deutliche Reduktion des PKP2-Wildtypproteins. Weiterhin konnten wir eine
Mutation in Intron 5 (c.631-2AG) im Gen des desmosomalen Cadherin Desmocollin
2 (DSC2) identifizieren, welche zu einer kryptischen Spleiß-Akzeptorstelle und
zu einem verfrühten Stopp-Kodon führt. Quantitative Analysen ergaben, dass die
kardiale DSC2-Expression deutlich verringert ist, bei gleichzeitigem Fehlen
des mutierten Transkriptes. Der Morpholino-Knockdown des DSC2-Orthologs im
Zebrafisch führt zur Reduzierung der desmosomalen Plaque-Fläche, zum Verlust
der extrazellulär gelegenen elektronendichten desmosomalen Mittellinie und ist
mit kardialen Kontraktilitätsstörungen assoziiert. Die Knockdown-Experimente
belegen die Notwendigkeit von DSC2 für die normale Herzentwicklung und
Funktion. Des Weiteren gelang es uns, einen neuen Lokus für die dilatative
Kardiomyopathie (DCM) mit diffuser myokardialer Fibrose und plötzlichem
Herztod auf Chromosom 10q25-q26 nachzuweisen. Die Identifizierung des
verantwortlichen Krankheitsgens in diesem Intervall könnte wichtige Hinweise
geben auf die zu Grunde liegenden Pathomechanismen von DCM und plötzlichem
Herztod.Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by the
replacement of right ventricular myocytes with fatty or fibrofatty tissue.
These pathologic changes lead to a clinical disorder with ventricular
tachyarrhythmias and sudden death. We have identified 32 heterozygous
mutations in the plakophilin-2 gene (PKP2) from 120 unrelated ARVC patients.
Plakophilin-2 is an essential arm repeat protein of the desmosome. Cardiac
desmosomes provide mechanical stability, transmit contractile force between
and participate in signal transduction in myocytes. The majority of PKP2
mutations introduce premature stop codons. Cardiac expression analysis
revealed absence of the truncated, and reduction of the normal plakophilin-2
protein in a patient with a PKP2 deletion mutation. We additionally identified
a heterozygous splice acceptor site mutation in intron 5 (c.631-2Aï ®G) of the
human desmocollin 2 (DSC2) gene, which led to use of a cryptic splice acceptor
site and the creation of a downstream premature termination codon.
Quantitative analysis of cardiac DSC2 expression in patient specimens revealed
a marked reduction in the abundance of the mutant transcript. Morpholino
knockdown in zebrafish embryos revealed the requirement for dsc2 in the
establishment of the normal myocardial structure and function with reduced
desmosomal plaque area, loss of the desmosome extracellular electron-dense
midlines and associated myocardial contractility defects. These data identify
DSC2 mutations as a cause for ARVC in humans, and demonstrate that physiologic
levels of DSC2 are crucial for normal cardiac desmosome formation, early
cardiac morphogenesis and cardiac function. In another study we were able to
map a novel locus for cardiomyopathy, diffuse myocardial fibrosis, and sudden
death to chromosome 10q25-q26. The identification of the causative gene in
this interval will be an important step in understanding the fundamental
mechanisms of heart failure and sudden death
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