171,259 research outputs found
Hetherington, Robert C.; Interview and Materials
No full textRoster Number: 549. Picture Location: Box 7 Folder 1. Interview Location: Box 2 Folder 4
Review of: Ancient Astronomy and Civilization by Norriss S. Hetherington
No full textThis article is a review of the book Ancient Astronomy and Civilization by Norriss S. Hetherington
Thomas Hetherington. Letter from the Secretary of the Interior relative to the claim of Thomas Hetherington for depredations committed by Cheyenne Indians in 1867.
No full text42-2ClaimsL-C of T. Hetherington. [1511] Cheyenne depredations of 1867 in Kansas.1872-3
Thomas Hetherington. Letter from the Secretary of the Interior relative to the claim of Thomas Hetherington for depredations committed by Cheyenne Indians in 1867.
No full textL-C of T. Hetherington. [1511] Cheyenne depredations of 1867 in Kansas
Hetherington featured in the Atlanta Journal-Constitution
No full textAssistant Clinical Professor & Wilbanks Child Endangerment and Sexual Exploitation Clinic Director Emma M. Hetherington was featured in the Atlanta Journal-Constitution regarding House Bill 479. The article titled Hidden Predator Act heads back to Georgia House was written by Amanda C. Coyne and published 3/11/20.
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Hetherington featured in the Atlanta Journal-Constitution
No full textAssistant Clinical Professor & Wilbanks Child Endangerment and Sexual Exploitation Clinic Director Emma M. Hetherington was featured in the Atlanta Journal-Constitution regarding House Bill 479. The article titled Hidden Predator Act heads back to Georgia House was written by Amanda C. Coyne and published 3/11/20.
Read the articl
Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters
No full textOur studies of the promoters of the myeloid CSF receptors (M, GM, and G) in cell lines have led to the findings that the promoters are small, and are all activated by the PU.1 and C/EBP proteins. To date, we have only found evidence for involvement of C/EBP alpha, although further experiments will be needed to exclude the role of C/EBP beta and C/EBP delta in receptor gene expression. These studies suggest a model of hematopoiesis (Fig. 2) in which the lineage commitment decisions of multipotential cells are made by the alternative patterns of expression of certain transcription factors, which then activate growth factor receptors which allow those cells to respond to the appropriate growth factor to proliferate and survive. For example, expression of GATA-1 activates its own expression, as well as that of the erythropoietin receptor, inducing these cells to be capable of responding to erythropoietin. Similarly, expression of PU.1 activates its own promoter, and turns on the three myeloid CSF receptors (M, GM, and G), pushing these cells along the pathway of myeloid differentiation. C/EBP proteins, particularly C/EBP alpha, are also critical for myeloid receptor promoter function, and may also act via autoregulatory mechanisms. Murine C/EBP alpha has a C/EBP binding site in its own promoter. Human C/EBP alpha autoregulates its own expression in adipocytes by activating the USF transcription factor. Myeloid genes expressed later during differentiation, such as CD11b, are also activated by PU.1, which is expressed at highest levels in mature myeloid cells, but not by C/EBP alpha, which is downregulated in a differentiated murine myeloid cell line. Consistent with this model are the findings that overexpression of PU.1 in erythroid cells blocks erythroid differentiation, leading to erythroleukemia, and overexpression of GATA-1 in a myeloid line blocks myeloid differentiation. While these findings have provided some framework for understanding myeloid gene regulation, there are a number of critical questions to be addressed in the near future: What is the pattern of expression of the C/EBP proteins during the course of myeloid differentiation and activation of human CD34+ cells? What is the effect of targeted disruption and other mutations of the C/EBP and AML1 proteins on myeloid development and receptor expression? What are the interactions among these three different types of factors (ets, basic region-zipper, and Runt domain proteins) to activate the promoters? What is the effect of translocations, mutations, and alterations in expression of these factors, particularly in different forms of AML
Hetherington and McMahon publish article in Children\u27s Rights Litigation
No full textClinical Associate Professor & Wilbanks Child Endangerment and Sexual Exploitation Clinic Director Emma M. Hetherington and third-year student Copelenn C. McMahon published Trauma-Informed Legal Representation for Youth in Sexual-Abuse-to-Prison Pipeline in 25 Children\u27s Rights Litigation (American Bar Association, 2023) (with A. Dunnigan)
Rhynie chert Prototaxites taiti dataset
No full text3D models of Prototaxites taiti from the 407 million year old Rhynie chert. Photogrammetry was used to capture the external 3D structure of two Rhynie chert blocks. Block North Sea Core (NSC) 36 and Lyon collection block 156. After describing the external surface of NSC36 we cut the specimen to investigate internal structure and produced another photogrammetry model of the cut specimen. Alongside our investigations with photogrammetry we produced a 3D model of complex tube branching within a medullary spot. This investigation was based on using confocal laser scanning microscopy to investigate thin section NMS G.2024.5.7 (MPEG0057). The dataset is related to the upcoming publication by Corentin C. Loron, Laura M. Cooper, Sean McMahon, Seán F. Jordan, Andrei V. Gromov, Matthew Humpage, Laetitia Pichevin, Hendrik Vondracek, Ruaridh Alexander, Edwin Rodriguez Dzul, Alexander T. Brasier, Alexander J. Hetherington. (In submission).>README.txt
A readme file providing information about the five image files.
>Images_of_sampled_fossils.zip
Images of fossils sampled by ATR-FTIR
>MPEG0057_2024_03_25__12_47_29_airyscan_Substack (1-114)_zstack.tif
Airyscan confocal z-stack produced from thin section National Museum Scotland (NMS) G.2024.5.7 (MPEG0057).
>MPEG0057 spot model.obj
3D model of medullary spot, produced from Airyscan confocal z-stack of thin section National Museum Scotland (NMS) G.2024.5.7 (MPEG0057)
>NSC36 whole block_scaled.oj
3D photogrammetry model of complete Rhynie chert Block North Sea Core (NSC) 36.
>NSC 36 cut_scaled.obj
3D photogrammetry model of Rhynie chert Block North Sea Core (NSC) 36, after the specimen had been cut.
>block 156 scaled.obj
3D photogrammetry model of Rhynie chert Lyon collection block 156
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