101,887 research outputs found
Sarcopenic obesity and associated body composition characteristics in individuals undergoing bariatric sugery: a retrospective study
No full textS279 Diabetologia (2023) 66 (Suppl 1):S1-S536 1 3 after bariatric surgery mitigating its positive effects on health status, leading to patient dissatisfaction and requiring the need for revisional surgery, which is associated with higher complication and mortality rates. Preoperative predictors contributing to IWL are not sufficiently studied. Therefore, we tried to identify preoperative predictors for IWL to identify patients at risk for IWL after bariatric surgery and thus to improve outcomes. Materials and methods: In this retrospective analytical study, patients who underwent sleeve gastrectomy (SG) or gastric bypass (GB) at our bariatric centre between March 2003 and December 2020 with complete 1 year follow-up data were included. IWL was defined as percentage excess weight loss (%EWL) less than 50% at 1 year after bariatric surgery. A total of 337 patients were included (83% female, 38% after SG, 62% after GB, BMI=46.4+-7.0 kg/m2, age 41+-11 years, from 17 to 67 years (means+-SD)). Kolmogorov-Smirnov test was used to assess the normality of quantitative data. A t-test was performed for parametric and a Mann-Whitney U test for non-parametric, continuous variables. A chi-squared test was performed for categorical variables. Results: 15% experienced IWL. The mean %EWL after 1 year was 82.1+-21.1% in the sufficient weight loss group and 35.8+-13.5% in the insufficient weight loss group. Predictors for sufficient weight loss were lower weight at baseline (p=0.023), lower BMI at baseline (p=0.02), higher HDL levels at baseline (p=0.025), gastric bypass as performed bariatric procedure (p=0.007) and no intake of ß-blockers (0.021). Age, waist circumference, sex, diabetes, HbA1c, fasting glucose and insulin, HOMA index, the intake of diabetes medication or insulin were no predictors for IWL. Conclusion: 15% of patients undergoing SG or GB experienced IWL defined as %EWL less than 50%. Predictors for sufficient weight loss were lower weight, lower BMI and higher HDL levels at baseline, gastric bypass as performed bariatric procedure and no intake of ß-blockers. Disclosure: V. Parzer: None. 551 Sarcopenic obesity and associated body composition characteristics in individuals undergoing bariatric sugery: a retrospective study Background and aims: Sarcopenia can coexist with obesity, together termed sarcopenic obesity (SO). SO is characterised by concomitant low muscle mass and function and excessive fat accumulation. As different relative indices of body composition are used to define SO, data on the prevalence of SO are divergent. This retrospective study aims to examine the prevalence of SO and its associations with pre-operative body composition characteristics, metabolic profile and weight loss success in bariatric surgery candidates. Materials and methods: Retrospective, cross-sectional study evaluating whole-body and regional body composition (assessed by dual-energy x-ray absorptiometry) and biochemical blood variables in adults (age 42±13 years) planned for bariatric surgery (n=78, 23% male, BMI 41.2±3.2 kg/m 2). SO diagnosis was based on sex-specific cut points for relative expressions of appendicular lean tissue mass (ALM, corrected for total body weight (ALM/w) or height squared (ALM/h 2)), as advocated by the Sarcopenic Obesity Global Leadership Initiative. Body composition variables, metabolic profile and weight loss (expressed as percentage total weight loss following surgery) were compared between ALM tertiles using Kruskal-Wallis and Mann-Whitney U tests
Sarcopenic obesity and associated body composition characteristics in individuals undergoing bariatric sugery: a retrospective study
No full textS279 Diabetologia (2023) 66 (Suppl 1):S1-S536 1 3 after bariatric surgery mitigating its positive effects on health status, leading to patient dissatisfaction and requiring the need for revisional surgery, which is associated with higher complication and mortality rates. Preoperative predictors contributing to IWL are not sufficiently studied. Therefore, we tried to identify preoperative predictors for IWL to identify patients at risk for IWL after bariatric surgery and thus to improve outcomes. Materials and methods: In this retrospective analytical study, patients who underwent sleeve gastrectomy (SG) or gastric bypass (GB) at our bariatric centre between March 2003 and December 2020 with complete 1 year follow-up data were included. IWL was defined as percentage excess weight loss (%EWL) less than 50% at 1 year after bariatric surgery. A total of 337 patients were included (83% female, 38% after SG, 62% after GB, BMI=46.4+-7.0 kg/m2, age 41+-11 years, from 17 to 67 years (means+-SD)). Kolmogorov-Smirnov test was used to assess the normality of quantitative data. A t-test was performed for parametric and a Mann-Whitney U test for non-parametric, continuous variables. A chi-squared test was performed for categorical variables. Results: 15% experienced IWL. The mean %EWL after 1 year was 82.1+-21.1% in the sufficient weight loss group and 35.8+-13.5% in the insufficient weight loss group. Predictors for sufficient weight loss were lower weight at baseline (p=0.023), lower BMI at baseline (p=0.02), higher HDL levels at baseline (p=0.025), gastric bypass as performed bariatric procedure (p=0.007) and no intake of ß-blockers (0.021). Age, waist circumference, sex, diabetes, HbA1c, fasting glucose and insulin, HOMA index, the intake of diabetes medication or insulin were no predictors for IWL. Conclusion: 15% of patients undergoing SG or GB experienced IWL defined as %EWL less than 50%. Predictors for sufficient weight loss were lower weight, lower BMI and higher HDL levels at baseline, gastric bypass as performed bariatric procedure and no intake of ß-blockers. Disclosure: V. Parzer: None. 551 Sarcopenic obesity and associated body composition characteristics in individuals undergoing bariatric sugery: a retrospective study Background and aims: Sarcopenia can coexist with obesity, together termed sarcopenic obesity (SO). SO is characterised by concomitant low muscle mass and function and excessive fat accumulation. As different relative indices of body composition are used to define SO, data on the prevalence of SO are divergent. This retrospective study aims to examine the prevalence of SO and its associations with pre-operative body composition characteristics, metabolic profile and weight loss success in bariatric surgery candidates. Materials and methods: Retrospective, cross-sectional study evaluating whole-body and regional body composition (assessed by dual-energy x-ray absorptiometry) and biochemical blood variables in adults (age 42±13 years) planned for bariatric surgery (n=78, 23% male, BMI 41.2±3.2 kg/m 2). SO diagnosis was based on sex-specific cut points for relative expressions of appendicular lean tissue mass (ALM, corrected for total body weight (ALM/w) or height squared (ALM/h 2)), as advocated by the Sarcopenic Obesity Global Leadership Initiative. Body composition variables, metabolic profile and weight loss (expressed as percentage total weight loss following surgery) were compared between ALM tertiles using Kruskal-Wallis and Mann-Whitney U tests
Distribution of K103N and/or Y181C HIV-1 mutations by exposure to zidovudine and non-nucleoside reverse transcriptase inhibitors
No full textR211K and L214F do not invariably confer high level phenotypic resistance to thymidine analogs in zidovudine-naïve patients with M184V
No full textBibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung
No full textDieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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3346: Samuel G. Freedman, author, 2013
No full textPhotograph of author Samuel G. Freedman, at NT Daily Slash meeting in the Mayborn School of Journalism at UNT
The Right to Strike under the United States Constitution: Theory, Practice, and Possible Implications for Canada
No full textAnswering critics of the Canadian Supreme Court's judgment in B.C. Health, the author argues that the Court laid the foundation for a principled and durable doctrine protecting constitutional labour rights, one that goes directly to the heart of the matter — the inequality of workers’ power in the employment relation. In the author’s view, two paths could lead from B.C. Health to the recognition of Charter protec- tion for a right to strike: one that treats the right as an accessory to col- lective bargaining, and one that upholds the right directly on the basis of the Charter values of equality and participation. The author supports the latter approach, contending that constitutional rights should be defined in relation to fundamental values, in a way that is not contingent on time-bound or fact-sensitive assessments about the role of strikes within a particular collective bargaining regime. Although a Charter right to strike may involve the courts in difficult choices about when to defer to legislative policy decisions, and courts may lack the institutional capac- ity to deal effectively with labour law issues, the author points out that judges can look to ILO standards for expert guidance. Noting that the U.S. experience in this area might be of considerable use to Canadians, the author concludes by providing an overview of American case law concerning a constitutional right to strike.Peer reviewe
G-Rank: Unsupervised Continuous Learn-to-Rank for Edge Devices in a P2P Network
No full textRanking algorithms in traditional search engines are powered by enormous training data sets that are meticulously engineered and curated by a centralized entity. Decentralized peer-to-peer (p2p) networks such as torrenting applications and Web3 protocols deliberately eschew centralized databases and computational architectures when designing services and features. As such, robust search-and-rank algorithms designed for such domains must be engineered specifically for decentralized networks, and must be lightweight enough to operate on consumer-grade personal devices such as a smartphone or laptop computer. We introduce G-Rank, an unsupervised ranking algorithm designed exclusively for decentralized networks. We demonstrate that accurate, relevant ranking results can be achieved in fully decentralized networks without any centralized data aggregation, feature engineering, or model training. Furthermore, we show that such results are obtainable with minimal data preprocessing and computational overhead, and can still return highly relevant results even when a user’s device is disconnected from the network. G-Rank is highly modular in design, is not limited to categorical data, and can be implemented in a variety of domains with minimal modification. The results herein show that unsupervised ranking models designed for decentralized p2p networks are not only viable, but worthy of further research.https://github.com/awrgold/G-RankComputer Scienc
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