4,318 research outputs found
J.C. Steyn Collection index
No full textThis index describes the J. C. Steyn collection which includes background material for 3 biographies by J.C. (Jaap) Steyn namely N.P. van Wyk Louw, P.J. Cillié and MER (M.E. Rothman). Prof. J.C. Steyn (1939-) is an educationist, linguist and author. Correspondence ; clippings ; photographs ; book reviews ; articles ; speeches ; varia compiled in 23 pamphlet boxes
Product Innovation Knowledge Transfer for Developing Countries: Towards a systematic Transfer Approach
No full textThe transfer of knowledge on product innovation to small- and medium-sized enterprises and local knowledge institutions in developing countries is expected to be one of the key drivers for competiveness and economical growth, and a part of the solution to environmental and social challenge. In that respect, this PhD study focuses on how the process of the current knowledge transfer takes place and how it can be improved. A combination of literature review and empirical research has resulted into a conceptual framework to describe the complex and dynamic process of product innovation knowledge transfer to developing countries. In order to improve this process, a systematic approach has been developed and operationalized by a needs assessment tool and a design manual: The UNEP Design for Sustainability for Developing Economies (D4S-DE) Manual (www.d4s-de.org). Both tools have been tested in practice by practitioners and have been evaluated by an academic review board.Design EngineeringIndustrial Design Engineerin
The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells
No full textThe NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro. Using a firefly luciferase-based silencing assay it is described here that NS3 is also active in mammalian cells. This activity is independent of the inducer molecule used. Using either synthetic siRNAs or a short hairpin RNA construct, NS3 was able to significantly suppress the RNAi-mediated silencing of luciferase expression in both monkey (Vero) and human (HEK293) cells. These results support the proposed mode of action of NS3 to act by sequestering siRNAs, the key molecules of the RNAi pathway conserved in all eukaryotes. The possible applications of this protein in modulating RNAi and investigating the proposed antiviral RNAi response in mammalian cell systems are discussed
Where do we draw lines: professional relationship boundaries and the child and youth care practitioner
No full textThe question of professional relationship boundaries is a poignant one, in light of the many boundary grey-zones that are created by the variety of young people’s needs, practice settings and professional relationship contexts within the field of child and youth care. In order to support practitioners’ development of critical thought and awareness of professional boundaries, this paper applies a professional relationship boundaries conceptual framework to child and youth care work, and the literature is consulted to explore the impacts of boundary violations, influences on individual’s boundaries, cues to indicate blurring boundaries, and key strategies to maintain balanced boundaries
Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants
No full textThe NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an alanine point mutational analysis was performed and the resulting mutant proteins were tested for both siRNA binding ability and RNAi suppressor activity in plants. Alanine substitutions of lysine residues at position 173-175 resulted in mutant proteins that lost both their affinity for siRNAs and their RNAi suppressor activity in planta. This indicates that siRNA binding of NS3 is indeed essential for the suppressor function of NS3 and that residues at position 173-175 are involved in the siRNA binding and suppressor activit
Anthropometry of the Beaver, Sekani, and Carrier Indians:
No full textby J.C. Boileau GrantBulletin (National Museum of Canada) ; 81. Bulletin (National Museum of Canada). Anthropological series. ; 18
J.C. Painter letter to Benjamin Lundy
No full textLetter from J.E. Painter to (presumably) Benjamin Lundy, answering a request for information about the history and operations of the Underground Railroad. Letter includes details of a story of an ex-slave transported on the Underground Railroad through Ohio and stories of the plight of other fugitive slaves crossing the Ohio River.
Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His "Genius of Universal Emancipation" was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
Turbulent wakes of plates with non-equilibrium similarity scalings
No full textWe have conducted hot wire anemometry measurements of six different axisymmetric turbulent wakes which demonstrate the existence in all these wakes of non-equilibrium mean flow profile scalings and of the underlying self-preservation and non-equilibrium dissipation scalings. These mean flow profile scalings are different from those of all documented canonical boundary-free turbulent shear flows to date, all of which have been established for very far downstream regions
Energy dissipation and flux laws for unsteady turbulence
No full textDirect Numerical Simulations of spatially periodic unsteady turbulence show that the high Reynolds number scalings of the instantaneous energy dissipation rate and interscale energy flux at intermediate wavenumbers are qualitatively different from the well-known cornerstone scalings of equilibrium turbulence where and are time-dependent rms velocity and integral length-scales. Instead, they both scale as where and are length and velocity scales characterizing initial/overall unsteady turbulence conditions
De werktuigen voor het bemalen van onze polders en boezems gedurende de afgeloopen 20 jaren
No full textRede, uitgesproken op 15 September 1919, bij overdracht van de waardigheid van Rector-Magnificus. Prof. ir. J.C. Dijxhoorn was rond de 1e wereldoorlog hoogleraar Werktuigbouwkunde aan de TU. Hij was ook Rector Magnificus van 1916-1919. Bij de overdracht van dit rectoraat heeft hij een lezing gegeven over de ontwikkeling van de Nederlandse gemalen in de periode van 1900 – 1920. [Transcriptie: H.J. Verhagen]Mechanical, Maritime and Materials EngineeringWerktuigbouwkund
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