24 research outputs found
Screening for abnormal eating attitudes in a population of Egyptian secondary school girls
No full textThe author screened a population of secondary school girls in Cairo, Egypt (n= 351), for abnormal eating attitudes, using a translated version of the Eating Attitude Test questionnaire (EAT-40). 11.4% scored positively on the questionnaire, a higher percentage than those reported by Mann et al (1983), Szmukler (1983) and Sabine et al (1988) of 6.9%, 6.2% and 8.2% respectively. This variance could be interpreted as a measure of genuine concern over weight or a reflection of a difference in the performance of the questionnaire in this population. In an attempt to determine the latter a confirmatory factor analysis was carried out modelled on Garner et al (1982) and Eisler & Szmukler (1985). The results of the analyses pointed to the coherence of the instrument which showed reasonable psychometric standards in this population. Three cases clearly fulfilled Russell's criteria for a diagnosis of a full syndrome of bulimia nervosa (1.2%), this is broadly in keeping with the rates of the UK studies of 1.9% and 1.1% in Cooper & Fairburn (1983) and King (1989) respectively. Twelve pupils (3.35) showed sufficient concern over their weight to qualify for partial syndrome of bulimia nervosa. The results of this study confirm the initial impression that disorders of eating are emerging in cultures that did not produce such morbidity before with more or less the same prevalence as in the UK. The author discussed the findings in relation to issues of cultural immunity and vulnerability in this respect, and concluded that no society is truly protected against the development of such disorders due to the globalisation of culture by virtue of the media.</p
The synthesis of trimethilamine from choline in rat liver
No full textPLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please log in with a valid BU account to access and click Download. If you are the author of this work and would like to make it publicly available, please contact [email protected] photographs.Thesis (D.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1989 (Nutritional Sciences.Bibliography : leaves 88-98.Endogenous trimethylamine (TMA) synthesis was investigated in rat tissues in vitro. Muscle or kidney homogenate did not demonstrate any ability to synthesize trimethylamine or trimethylamine oxide (TMAO) from choline. However, liver homogenate did make TMA and TMAO from choline. This reaction was not due to bacterial conversion of choline since aseptic preparation and incubation of liver homogenate produced similar amounts of TMA. TMA synthesis from choline in liver subcellular fractions was then investigated. This phenomenon was found to be associated with the mitochondrial fraction.
The direct precursor for this reaction was investigated. TMAO, or betaine were not precursors for TMA. Betaine aldehyde, an oxidation product of choline, made more TMA than did choline. Phosphocholine produced some TMA but it was not as good a precursor as was choline or betaine aldehyde. Choline oxidase inhibitors, rotenone and low oxygen, both inhibited TMA synthesis from choline. This suggests that choline oxidase, possibly via formation of betaine aldehyde, is involved in the conversion of choline to TMA.
This work demonstrates, for the first time, the existence of a pathway for TMA synthesis in mammals. The author suggests choline as the precursor for this reaction via betaine aldehyde.
This reaction is carried out in two steps. First, choline aldehyde dehydrogenase, in liver mitochondria, converts choline to betaine aldehyde. Second, betaine aldehyde is then converted to TMA
RELATIONSHIP BETWEEN HEALTH CARE ORGANIZATIONAL CHARACTERISTICS AND NURSES' INNOVATIVE BEHAVIOR
No full textAbstract: Nurses need management support, resources, supportive work environment, and autonomy to make decision, gain knowledge about innovation, and engage in role related to innovative behavior. Aim: to examine the relationship between health care organizational characteristics and nurses’ innovative behavior. Methods: A descriptive, correlational research design was conducted at Fever, Chest and Kafr El-Dawar General Hospitals, at EL-Beheira Governorate- Egypt. Subjects: All staff nurses, who are working in the previously mentioned settings and who were available at the time of data collection, with at least one year of experience, were included in the study (N=220). Tools: Organizational Characteristics Scale and Nurses Innovation Behavior scales. Results: There was significant relationships between health care organizational characteristics and nurses’ innovative behavior, where (p-value ≤ 0.05). Moreover, there were highly statistical significant differences between health care organizational characteristics and its dimensions; management support, where (P ≤ 0.01). Also, there was statistically significant difference between staff nurses’ innovative behavior and idea generation. Conclusion: nurses’ innovative behavior is the outcomes of health care organizational characteristics. Recommendations: Enhance nurses’ innovative behavior through participation in the application of health care organization strategies, such as: decisions making; delegation and problem solving…etc
Keywords: organizational characteristics, innovation behavior.
Title: RELATIONSHIP BETWEEN HEALTH CARE ORGANIZATIONAL CHARACTERISTICS AND NURSES' INNOVATIVE BEHAVIOR
Author: Aisha Saad Nassar, Reem Mabrouk Abd El Rahman, Mervat Abd El Monem Aref, Mayada Hassan El Zoheiry
International Journal of Novel Research in Healthcare and Nursing
ISSN 2394-7330
Vol. 10, Issue 3, September 2023 - December 2023
Page No: 28-42
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 06-September-2023
DOI: https://doi.org/10.5281/zenodo.8321458
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/RELATIONSHIP%20BETWEEN%20HEALTH-06092023-3.pdfInternational Journal of Novel Research in Healthcare and Nursing, ISSN 2394-7330, Novelty Journals, Website: www.noveltyjournals.co
Re-mapping adolescence : psychoanalysis and narrative in young adult fiction.
Full text linkThe start of the new millennium has witnessed literary interest in young adult fiction and a prominent rise in its popularity. My research focuses on the dynamics of adolescent narrative and the representations of the adolescent subject in a number of contemporary mainstream young adult novels with the aim of understanding adolescence as an inscribed literary identity. I take, as my starting point, Julia Kristeva's definition of adolescence as an open, non-biologically limited, psychic structure. This notion, when applied to young adult fiction, suggests that the texts work to construct psychologically-open implied readers, which in diverse ways echo and affirm the desires and expectations of real readers.
While the introduction surveys contemporary critical currents in children and young adult fiction and places my research into context, each of the subsequent chapters examines one or more literary works by a single author. The main literary works discussed in this study include novels by Meg Rosoff, Geraldine McCaughrean, David Almond, J K Rowling and Philip Pullman respectively; all of whom have widely appealed to readers of different age groups.
In my analysis I use insights from psychoanalytic and psycho-linguistic theories mainly by Kristeva, Freud, Lacan and Winnicott, and where necessary my argument is supported by narrative analysis, reading theories and feminist criticism.
By engaging with critical and psychoanalytical readings of paradigmatic young adult texts, I aim to explicate the particularities of representing the adolescent economy and the distinctive nature of contemporary young adult fiction in ways through which it opens its boundaries to adult readers. On another level, my objective is to elucidate the growing complexities and subtleties of contemporary children's literature in general and young adult fiction in particular
Inhibition of Rhizoctonia solani Growth and Its Extracellular Hydrolytic Enzymes by Different Extracts of Cinnamon (Cinnamomum cassia) and Black Cumin Seeds (Nigella sativa)
No full textThe present study evaluated the ability of different extracts of cinnamon and black cumin seeds to inhibit the growth of the phytopathogenic fungus Rhizoctonia solani and its extracellular cell wall degrading enzymes. Concentrations of 300 and 450 ppm of methylene chloride and hexane extracts of cinnamon completely inhibited the growth of R. solani after 72 hours of incubation at 25±1°C in vitro. Methylene chloride or hexane extracts of black cumin seeds at 4000 ppm after 72 hours inhibited the growth of R. solani by 37 and 39% respectively. Moreover, black cumin seed hexane extract at 2000 ppm inhibited 55% and 38% of the activity of pectin lyase (PL) and polygalacturonase (PG) respectively. In addition, the methanolic extract of black cumin seeds at 2000 ppm exhibited a significant reduction of exo-protease activity (74.8%). GC-MS analysis results showed that linoleic acid is the main component of the fixed oil fraction of black cumin seed hexane extract while (E) cinnamaldehyde is the main component in both hexane and methylene chloride extracts of cinnamon. HPLC-MS analysis of black cumin seeds methanolic extract showed that amentoflavone was the main component. Docking was used to identify the major component interaction with pectin lyase A and exo-protease
Effect of Maternal Diabetes on Pre- and Post-Natal Redox Status of F1 Rat Offspring
No full textBackground: The oxidative stress and disturbed redox signaling during gestation my play an im-portant role in the fetal programming of adult diabetes. Objective: The study aimed to investigate the effects of maternal diabetes on pre- and post-natal pancreatic and peripheral tissues redox and oxidative status in order to clarify their role in the diabetogenic programming of F1 offspring. Methods: Two groups of female Wistar rats were used (diabetic and control); diabetes was neona-tally induced by STZ injection to 5-day old rats. 10 pregnancies of each group were terminated at GD 17 to obtain placentas and fetal pancreas, liver, muscle and adipose tissues for prenatal mea-surements. The rest of pregnancies were completed to term and the offspring were weaned to control diet or high-caloric (HCD) diet and followed up for 30 weeks. Every 5 weeks 10 male rats were sacrificed and serum and tissues were obtained for assessment of fasting blood glucose, tis-sues content of 8-oxo-dG, TBARS, GSH, GSSG, antioxidant enzymes and caspase-3. Results: The re-sults indicated that, prenatally redox status of the foetuses of diabetic mothers is shifted toward more oxidizing environment which results from elevated oxidative stress and impaired antioxi-dants as indicated by elevated fetal tissues content of 8-oxo-dG, TBARS and GSSG and decrease
Effect of Modified Clinical Pathway Guidelines on Congestive Heart Failure Critically Ill Patient's Health Outcomes at Assuit University Hospital, Egypt
Full text linkLiterature review cited that, congestive heart failure critically ill patients are suffering from different health problems which might endanger their lives and safety, compromise their quality of life, and burden hospital resources. Critical care nurses play major role together with the other health care team members in integrating and delivering multidisciplinary health care for such group of patients. This care approach can positively been reflected upon patient’s outcomes and other related variables. Therefore, the aim of this study is to investigate the effect of modified clinical pathway guidelines on congestive heart failure critically ill patients' health outcomes. Research hypothesis; critically ill congestive heart failure patients who are subjected to the modified clinical pathway guidelines in addition to the routine hospital care will Show; 1- More hemodynamic stability,2- Lesser exposure to chest pain and dyspnea attacks, 3- Fewer systemic complications, 4- Lesser CCU stay / days and the numbers of re-hospitalizations, 5- Lesser degree of dependent edema and grade of heart failure, and 6 - Report lesser numbers of negative variables than that of a matched control group of patients whom received the routine hospital care only. Quasi-experimental research design was used to conduct this study. Setting; the current study was conducted at the Coronary Care Unit of Assuit University Hospitals, Egypt. Sample; sixty adult male and female critically ill congestive heart failure patients were included in this study and assigned randomly into two equal and matched groups, (study and control of 30 patients each). Tools: Four tools were developed and tested by the investigators. These tools are; I: Congestive heart failure critically ill patient’s assessment sheet, II Congestive heart failure critically ill complications monitoring sheet, III: Congestive heart failure critically ill Patient’s health outcomes assessment sheet, and IV: Modified clinical pathway guidelines variances checklists Congestive heart failure critically ill Patient’s health outcomes assessment sheet. Setting: Coronary Care Unit (CCU) of El-Or man Hospital, Assuit University Hospitals, Egypt. Methods: The researchers trained, participated in coordinating, and supporting the implementation of the clinical pathway guidelines, and then evaluated its effects on the selected congestive heart failure critically ill patients’ health outcomes. Results of this study revealed that, patients in modified clinical pathway guidelines group got significantly lesser chest pain and dyspnea attacks, decreased weight gain, fewer systemic complications; shorter length of hospital stay / days, with lesser negative variables than that of the control group subjects. Thus the complex research hypothesis can be partially supported. Conclusion: Applying modified clinical pathway guidelines could significantly improve patient's health outcomes in congestive heart failure critically ill patients. Recommendations: Clinical pathway care approach needs to be supported and initiated in the CCU at Assuit University Hospitals with furthermore replications of this study and other related studies on a larger probability samples in relation to patient’s health outcomes, safety, and hospital resources. Keywords: Congestive Heart Failure Critically ill patients, Modified Clinical Pathway Guidelines, Clinical Pathway, and Patient's Health Outcomes
An Evaluation of the Presentation of Islam in John Updike’s Terrorist
No full textThis thesis exposes Updike’s overt racialist attack on Islam in his novel Terrorist (2006).
It proves that his presentation of Islam is based on inherited stereotyped myths and lies. It also
proves his failure to cross linguistic, cultural, and ideological boundaries to write about the
“Other.” The thesis focuses on the demeaning characterization of Muslims and the false
objectivity in constructing characters. The thesis discovers and exposes the manipulation and
misinterpretation of the quoted Quranic texts in addition to other allegations against Islam
especially jihadist thinking, women and enjoyment of life. The author claims a moral, mental,
and physical inferiority of minor ethnic groups of color as Arabs, Africans, Hispanics and
Asians, and celebrates the superiority of the white American race beside defending the ideals of
the American society. The thesis thus concentrates on the dominant colonial/racialist discourse in
the narrative, and proves the author’s partiality. In addition to that this study investigates
Updike’s treatment of secularism, Christianity and Judaism to help highlight his prejudiced
views about Islam
Therapeutic effect of rupatadine against L-arginine-induced acute pancreatitis in rats: role of inflammation
Full text linkAcute pancreatitis (AP) is an abrupt inflammatory disorder causing high morbidity and mortality. As AP is an insidious medical emergency, a curative modality is required instead of a preventive measure. Thus, we investigated the possible curative effect of rupatadine on a rat model of AP. Rupatadine is a potent histamine receptor 1 (H1R) and platelet-activating factor (PAF) blockers. We used four groups of six Wistar rats as follows: the control group received vehicle, the rupatadine control group received rupatadine 6 mg/kg orally, the AP group received L-arginine intraperitoneal, and the treatment group received rupatadine at 1, 6, and 24 h after L-arginine injection. The levels of serum amylase, pancreatic oxidative parameters, and pancreatic cytokines were measured. PAF, histamine, and myeloperoxidase levels were determined in the pancreas. Histopathological and immunohistochemical examinations were performed to determine nuclear factor kappa-B (NF-κB) and caspase 3 expressions. Oxidative damage and severe inflammation were detected in the pancreas of the AP group. Rupatadine reduced the oxidative damage and the levels of proinflammatory cytokines, PAF, histamine, and myeloperoxidase and NF-κB and caspase 3 expressions. It restored the pancreatic acini to almost the normal condition. Rupatadine induced important anti-inflammatory and antiapoptotic effects against L-arginine-induced AP.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author
Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model
Full text link[Aims]: Evaluation of the anti-diabetic effect of superparamagnetic iron oxide nanoparticles (SPIONs) on Type 2 diabetic rats and compared their effect to metformin treatment.[Main methods]: Diabetic rats were treated with different doses of nanoparticles one time per week for 4 weeks. Fasting blood glucose level was determined for studied groups during the experimental period (30 days). At the end of the experiment, oral glucose tolerance test was carried out, serum samples were collected for biochemical assays. Then animals were sacrificed to obtain tissues for assessment of glucose transporters, insulin receptors and insulin signaling proteins.[Key finding]: SPIONs treatment normalized fasting blood glucose and lowering insulin level in diabetic rats compared to untreated diabetic rats. SPIONs significantly ameliorate the glucose sensing and the active components of insulin signaling pathway. The anti-diabetic effects of SPIONs may be mediated through its effect on (i) hepatic peroxisome proliferator-activated receptor gamma coactivator 1-alpha content, which induced by SPIONs treatment in a dose-dependent manner, (ii) adipocytokines as SPIONs treated diabetic rats showed significantly higher levels of adiponectin and lower retinol binding protein 4 compared to untreated diabetic rats, (iii) lipid profile as SPIONs treatment significantly corrected the lipid profile in a dose-dependent manner and to a similar extent as metformin or even better.[Significance]: To our knowledge, this is the first study that explores the anti-diabetic effects of SPIONs on diabetic model.This work was partially supported by the Spanish Ministry of Science, Innovation and Universities (Grant PGC2018-095795-B-I00) and by the European Union's Horizon 2020 FET Open Programme (Grant no. 801305).Peer reviewe
