1,252 research outputs found

    Depressive symptoms predict recurrence of atrial fibrillation after cardioversion

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    Objective: The aim of this study was to evaluate whether depressive symptoms and the type-D personality are predictive of early recurrence of atrial fibrillation (or atrial flutter; AF) after successful electrical cardioversion (CV). Background: Depressive symptoms are associated with an adverse prognosis in patients with coronary artery disease, congestive heart failure, and ventricular arrhythmias. Anger and hostility have been shown to be predictive of development of AF. However, little is known about the effects of depression on AF. Methods: Fifty-four patients with persistent AF completed the Hospital Anxiety and Depression Scale (HADS) and the Type D Scale (DS-14) prior to elective electrical CV Patients with a successful CV were followed for 2 months. Results: During the follow-up period, 27 patients (50%) had recurrence of the arrhythmia. Depressive mood (HADS depression scale > 7) was the only significant nonsomatic predictor of recurrence, which was observed in 85% of depressed versus 39% of nondepressed patients [odds ratio=8.6; 95% confidence interval (CI)=1.7-44.0, P=.004]. HADS anxiety scores and the presence of the type-D personality pattern were not associated with recurrence of AF. On multivariate Cox regression analysis, including variables with a prevalence > 10% of the total study population and a univariate discriminative effect yielding a P value of 7 was found to be the only independently predictive variable of arrhythmia recurrence (hazard ratio=2.7; 95% CI=1.05-7.2; P=.046). Conclusions: Our results indicate that depressive mood is a major risk factor for recurrence of AF after electrical CV Heightened adrenergic tone and a proinflammatory state are possible mechanisms responsible for the observed association. Identification of depression may be of value prior to the decision to perform electrical CV. (c) 2007 Elsevier Inc. All rights reserved

    Type D Personality is Unrelated to Major Adverse Cardiovascular Events in Patients with Coronary Artery Disease Treated by Intracoronary Stenting

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    Previous research in cardiac patients suggested that type D personality, defined as a combination of negative affectivity (NA) and social inhibition (SI), was associated with adverse outcome. The objective of this prospective study was to examine the independent prognostic value of type D in patients with coronary artery disease (CAD). A total of 465 patients completed the Type D Scale (DS14) questionnaire before undergoing stent implantation and were followed up for 5 years. In a Cox regression model adjusted for selected confounders, we found a trend towards NA for the prediction of nonfatal major adverse cardiovascular event (MACE, hazard ratio (HR) = 1.07, 95 % confidence intervals (CIs) = 0.99-1.14, p = 0.074), while, in contrast, SI was a significant and independent predictor of better outcome (HR = 0.92, 95 % CI = 0.86-0.99, p = 0.027). In a cohort of CAD patients, the type D pattern was not linked to adverse outcome, whereas SI was negatively associated with MACE

    Anxiety is associated with a reduction in both mortality and major adverse cardiovascular events five years after coronary stenting

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    Objective Previous studies in post-myocardial infarction patients with heart failure have documented that high anxiety levels are associated with increased mortality. In this prospective study, we determined the impact of anxiety on long-term event risk in stable coronary heart disease (CHD) patients treated with percutaneous coronary interventions (PCIs). Methods A total of 470 patients referred for PCI completed the Hospital Anxiety and Depression Scale (HADS) before undergoing stent implantation. Over a five-year follow-up period, data on survival, occurrence of major adverse cardiovascular events (MACEs) and repeat revascularization were obtained from n=462 participants (98.3%). Results All-cause mortality rates differed significantly across the four quartiles of the HADS anxiety subscale, the lowest number of deaths (1.9%) being seen in patients with the highest HADS-A quartile (scores10) as compared to those in the three lower quartiles (11.8%, odds ratio=0.14, 95%-confidence interval (95% CI): 0.03-0.60, p=0.002). Cox regression models adjusted for a variety of potential somatic and procedural confounders confirmed the results from the univariate analyses (hazard ratio (HR)=0.21, 95% CI: 0.05-0.91, p=0.037). There were also fewer MACEs in anxious patients as compared to non-anxious subjects (HR=0.34, 95% CI: 0.14-0.80, p=0.014). In contrast, anxious patients had a higher rate of repeat revascularization (26.4% versus 16.6%, p=0.033). Conclusions In CHD patients undergoing elective PCI, higher anxiety levels are positively associated with survival and reduce the risk for MACE during the first five years after index PCI. The beneficial effects of anxiety on cardiovascular mortality and morbidity suggest that a differentiated approach to diagnosing and treating anxiety in CHD patients is warranted

    Transient impact of baseline depression on mortality in patients with stable coronary heart disease during long-term follow-up

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    The objective of this prospective study was to determine the impact of depressive symptoms on long-term survival in coronary heart disease (CHD) patients treated with intracoronary stenting. Four hundred and seventy patients completed the Hospital Anxiety and Depression Scale (HADS) before undergoing stent implantation and were followed over a 5-year period. Survival data were collected from n = 462 participants (98.3 %). A cut-off a parts per thousand yen8 on the HADS depression subscale was used to indicate probable clinical levels of depression. All-cause mortality rates differed significantly between depressed and non-depressed patients at 2-year follow-up, as 6 out of 98 subjects with elevated HADS-D scores (6.1 %), but only 8 out of 364 (2.2 %) patients with normal HADS-D scores had died [odds ratio = 2.9, 95 % confidence interval (95 % CI) = 1.0-8.6, p = 0.044]. In a Cox regression model adjusted for sociodemographic and clinical parameters, positive HADS-D scores [hazard ratio (HR) = 4.3, 95 % CI = 1.2-15.4, p = 0.025], body-mass index (HR = 0.8, 95 % CI = 0.7-1.0, p = 0.040) and stent length (HR = 1.1, 95 % CI = 1.0-1.1, p = 0.042) independently predicted 2-year survival. From the third to the fifth year after index PCI, the frequency of deaths in the depressed patients' group did not significantly differ from that observed in non-depressed patients (5.5 % versus 7.0 %, p = 0.607), and the predictive role of baseline HADS-D scores for survival was lost. In CHD patients, self-rated depressive symptoms at baseline were negatively linked to survival at 2-year follow-up, but failed to predict mortality 3 years later. Thus, in contrast to other well-established risk factors, the prognostic value of depression for predicting adverse outcome may be temporarily limited. The mechanisms behind this transient effect need further study

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Group living homes for older people with dementia: Concept and effects

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    Eefsting, J.A. [Promotor]Pot, A.M. [Promotor]Depla, M.F.I.A. [Copromotor]Lange, J. de [Copromotor

    The work of grief and the work with grief. Therapy and autotherapy with help of photography

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    In this article paper, the author presents her own experience of working as a photographer, using photography (or, more broadly, a photographic session) as an action that facilitates coping with the experience of loss. The article describes two types of bereavement sessions: the Memoir project and the Trauer project. In the first of the projects, the author took photographs and helped to conduct the session. In the latter case, she was both a performer and photographer. Both sessions had the intended effect and fit into the theoretical framework to which the author refers in the paper.Autorka zaprezentowała w artykule własne doświadczenia pracy fotografa stosującego fotografię (czy szerzej: sesję fotograficzną) jako działanie ułatwiające radzenie sobie z doświadczeniem straty. W tekście opisane zostały dwa rodzaje sesji odnoszących się do pracy z żałobą: projekt Memoir i projekt Trauer. W przypadku pierwszego z nich autorka wykonywała fotografie i pomagała w przeprowadzeniu sesji. W drugim była zarówno performerką, jak i wykonawczynią zdjęć. Obie sesje przyniosły zamierzony efekt i wpisują się w teoretyczne ramy, do których nawiązuje autorka

    Two Anti-Utopian Visions – <i>We</i> by Yevgeny Zamyatin and <i>Miranda</i> by Antoni Lange: History of Idea and Reception

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    Artykuł stanowi próbę zaprezentowania dwóch antyutopijnych powieści powstałych w latach dwudziestych XX wieku: My Jewgienija Zamiatina (1920) i Mirandy Antoniego Langego (1924). Autor przedstawia w nim genezę obu tekstów, a także wskazuje kulturowe, artystyczne i ideowe płaszczyzny ich odczytania. Omawia recepcję My i Mirandy oraz stan badań nad twórczością antyutopijną Zamiatina i Langego. Stara się ująć obie powieści w kontekście rozwoju gatunku. Ponadto ukazuje My Zamiatina i Mirandę Langego jako wypowiedzi o charakterze historiozoficznym, uwikłane często w dyskusje z dominującymi prądami artystycznymi i estetycznymi.The article attempts to present two anti-utopian novels written in the 1920s: We by Yevgeny Zamyatin (1920) and Miranda by Antoni Lange (1924). The author examines origins of both texts and points out cultural, artistic and ideological aspects of their interpretation. The reception of We and Miranda is discussed as well as the current state of research on the anti-utopian oeuvre of Yevgeny Zamyatin and Antoni Lange is addressed. The author attempts to present both novels in the context of evolution of the literary genre. Moreover We by Zamyatin and Miranda by Lange are depicted as statements of historiosophical character, often embroiled in disputes with the dominating artistic and aesthetic movements
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