1,721,096 research outputs found

    Compartmentalization effects in geologic CO2 sequestration. A case study in an offshore reservoir in Italy

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    The implementation of suitable carbon capture and storage (CCS) technologies is a mandatory requirement for reducing anthropogenic emissions of greenhouse gases (GHG) and obtaining a sustainable power generation from fossil fuels, especially coal. Carbon dioxide (CO2) sequestration within deep underground reservoirs is indicated as one of the most promising techniques which, however, implies a complex multidisciplinary effort involving a number of hydrological, geomechanical and geochemical issues. In the present contribution a geomechanical modeling study of the CO2 disposal intoan offshore multi-compartment saline aquifer located at about 1500 m depth in the Northern Adriatic Sea, Italy, is discussed. The study assumesa CO2injection rate of 1×10^6 ton/a and shows that a safe and permanent containment may be secured over a few years only for the considered distributions of the petrophysical properties and initial in-situ stress and pore pressure

    A coupled poroelasticity model by Mixed Finite Elements for aquifer recharge simulations

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    In real-world applications involving complex 3D heterogeneous domains the use of advanced numerical algorithms is of paramount importance to solve stably, accurately and efficiently the coupled system of partial differential equations (PDEs) governing the mass and the energy balance in deformable porous media. The present paper discusses a novel coupled 3D numerical model based on a combination of Finite Elements (FE) and Mixed FE (MFE) developed with the aim at stabilizing the numerical solution

    Utility of serum complement factors C3 and C4 as biomarkers during therapeutic management of giant cell arteritis

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    Objective There is a strong unmet need for biomarkers in giant cell arteritis (GCA), as C-reactive protein (CRP) may be unreliable in patients treated with Tocilizumab (TCZ). We aimed to assess whether C3 and C4 are useful biomarkers in GCA patients, particularly in those treated with TCZ. Method We retrospectively enrolled all patients who underwent C3 and C4 measurement at baseline. All patients were evaluated at 3, 6, 12, and 24 months after diagnosis, as part of routine follow-up. Two assessments after the end of the observational period, in case of further relapses, were also included. Results At baseline, mean +/- sd levels (mg/dL) of C3 (133 +/- 28.99) and C4 (25.9 +/- 9.04) were within normal ranges. During follow-up, C3 and C4 decreased in patients attaining remission (107.07 +/- 19.86, p = 0.0006; 19.86 +/- 10.27, p = 0.01, respectively) and sustained remission (95.85 +/- 18.04, p = 0.001; 15.61 +/- 9.75, p = 0.006). In TCZ-treated patients, even stronger decreases in C3 (83.11 +/- 19.66, p = 0.001) and C4 (8.26 +/- 3.83, p < 0.0001) were observed, and their values were not correlated with CRP or erythrocyte sedimentation rate. Conclusion C3 and C4 do not seem useful in the diagnosis of GCA, as normal values do not rule out active vasculitis. However, C3 and C4 correlate with disease activity. As the low C4 levels found in TCZ-treated patients are not correlated with CRP, C4 should be evaluated as a potential biomarker of disease activity and treatment response

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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