6,252 research outputs found
sj-pdf-1-jiv-10.1177_08862605221081934 – Supplemental Material for Potential Reporters of Suspected Child Maltreatment are Sensitive to the Amount of Evidence and the Potential Consequences of Reporting
Supplemental Material, sj-pdf-1-jiv-10.1177_08862605221081934 for Potential Reporters of Suspected Child Maltreatment are Sensitive to the Amount of Evidence and the Potential Consequences of Reporting by Heather L. Price and Andre Kehn in Journal of Interpersonal Violence</p
Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart
Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species generation, but at the cost of impaired electron transport chain (ETC) activity. Dietary nitrate supplementation improves mitochondrial efficiency and can promote tissue oxygenation by enhancing blood flow. We therefore hypothesised that ETC dysfunction, impaired energetics and oxidative damage in the hearts of rats exposed to chronic hypoxia could be alleviated by sustained administration of a moderate dose of dietary nitrate. Male Wistar rats (n = 40) were given water supplemented with 0.7 mmol l(-1) NaCl (as control) or 0.7 mmol l(-1) NaNO3, elevating plasma nitrate levels by 80%, and were exposed to 13% O2 (hypoxia) or normoxia (n = 10 per group) for 14 days. Respiration rates, ETC protein levels, mitochondrial density, ATP content and protein carbonylation were measured in cardiac muscle. Complex I respiration rates and protein levels were 33% lower in hypoxic/NaCl rats compared with normoxic/NaCl controls. Protein carbonylation was 65% higher in hearts of hypoxic rats compared with controls, indicating increased oxidative stress, whilst ATP levels were 62% lower. Respiration rates, complex I protein and activity, protein carbonylation and ATP levels were all fully protected in the hearts of nitrate-supplemented hypoxic rats. Both in normoxia and hypoxia, dietary nitrate suppressed cardiac arginase expression and activity and markedly elevated cardiac l-arginine concentrations, unmasking a novel mechanism of action by which nitrate enhances tissue NO bioavailability. Dietary nitrate therefore alleviates metabolic abnormalities in the hypoxic heart, improving myocardial energetics
Madison Price Family History
Madison L. Price authored this family history as part of the course requirements for HIST 550/700 Your Family in History offered online in Fall 2019 and was submitted to the Pittsburg State University Digital Commons. Please contact the author directly with any questions or comments: [email protected]
Price support at any price? Costs and benefits of alternative agricultural policies for Poland
The author argues that Poland must choose an agricultural policy that promotes efficiency, structural change, and adjustment to the new market environment and eventual membership in the European Union. That policy must take into account both the needs of, and the financial constraints on, Polish agriculture. Results of simulation experiments performed with the use of the computable general equilibrium model of the Polish economy suggest that Common Agricultural Policy-type price supports are not the most efficient agricultural policy for Poland. The author discusses alternative policies and scenarios. Rather than discuss whether the relationship between farmers'incomes and average Polish wages is fair, the author analyzes whether medium- and long-term development trends in the Polish economy may cause this relationship to deteriorate, and what policies will counteract those trends. Rapid growth in the nonagricultural sectors combined with real appreciation of domestic currency (caused either through good current account performance or significant capital inflows) may jeopardize farmers'relative income position. And such developments are probable if positive projections for economic development and membership in the European Union are realized. The agricultural sector can defend its relative income only by becoming more efficient. Price supports improve farmers'relative income but at a high cost to taxpayers and consumers and to macroeconomic efficiency. To meet these costs, Poland must put in place firm quantity controls. But the author thinks that the best strategy would be to avoid price supports until the moment of joining the European Union's Common Agricultural Policy. In the interim, policies aimed at reducing farm employment seem most appropriate. The author discusses two such policies: encouraging older farmers to retire and promoting jobs in rural areas. He also proposes two feasible scenarios for integrating Polish agriculture with that of the European Union by 2005-10.Markets and Market Access,Economic Theory&Research,Environmental Economics&Policies,Labor Policies,Agricultural Knowledge&Information Systems,Economic Theory&Research,Environmental Economics&Policies,Agricultural Knowledge&Information Systems,Markets and Market Access,Access to Markets
Socio-economic survey of domestic groundwater handling and use for source owners in Kisumu, Kenya in 2014
This datasets contains the anonymised results of a survey of well owners in Kisumu, Kenya. Data includes information on the amount of water abstracted daily from the well and ways in which this water was used and handled, information on other sources of water (e.g. piped utility water and rainwater) and how this is used, and the assets and services that the well owner has access to. Answers from questions to assess food poverty are also included. The surveys were carried out during February and March 2014 and include data from 51 well owners. The data were collected as part of the Groundwater2030 project, which aims to reduce the health problems that result from consumption of contaminated groundwater in urban areas of Africa. The project was co-ordinated by the University of Southampton, with partners at the University of Surrey, the Victoria Institute of Research on Environment and Development (VIRED) International, and the Jaramogi Oginga Odinga University of Science and Technology. The project was funded by the Natural Environment Research Council and the Department for International Development as part of the Unlocking the Potential of Groundwater for the Poor (UPGro) programme.</span
Endogenous Fixprices and Sticky Price Adjustment of Risk-averse Firms
A risk-averse price-setting firm which knows the quantity demanded at the status quo price but has imperfect information otherwise may choose not to change it although an otherwise identical risk-neutral firm would do so, provided the variance of the firm's subjective probability distribution over quantities demanded as a function of price displays a kink at the status quo. This is equivalent to risk aversion of order one. When no such endogenous fixprice exists, the size of price adjustment still tends to zero as risk aversion tends to infinity, and to any arbitrarily small menu cost there exists a degree of risk aversion so that the firm will not adjust.fixed prices, price adjustment, risk aversion, menu cost
Intercommodity price transmittal : analysis offood markets in Ghana
This report expands on a dynamic model of market integration to investigate how information is transmitted across commodities. The author investigates one property of an efficient market : the full use of available information. Studies of spatial price integration simultaneously looks at the flow of information and commodities. The author investigates the flow of information within a single spatial market and the relationship between prices in spatially separate markets. He studies intercommodity price transmittal from two perspectives. First, he asks whether the government can concentrate on a single commodity price, yet achieve policy objectives in a broader arena. This is important in Ghana because no single commodity dominates consumers'food budgets. The author finds that price movements for the main cereal consumed in the country (maize) are fully transmitted to other regions. Second, he investigates the working of commodity markets in developing countries. He notes imperfections in the way markets process information. There are several possible explanations for this market inefficiency. Traders may set prices for other coarse grains in response to information about maize prices. Another possibility is that some traders may not deal in all grains and thus have different costs of acquiring information. In short the author's dynamic model of price integration indicates functional efficiency in Ghana.Access to Markets,Markets and Market Access,Environmental Economics&Policies,Economic Theory&Research,Agricultural Research
sj-docx-1-jiv-10.1177_08862605221137708 – Supplemental material for The Impact of the Consistency of Child Witness and Peer Reports on Credibility
Supplemental material, sj-docx-1-jiv-10.1177_08862605221137708 for The Impact of the Consistency of Child Witness and Peer Reports on Credibility by Victoria W. Dykstra, Rachael Van der Kant, Celine E. Keller, Kaila C. Bruer, Heather L. Price and Angela D. Evans in Journal of Interpersonal Violence</p
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