49 research outputs found

    The Aftermath of Flood Crises- Diphtheria Outbreak in Sindh

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    Hydraulic simulations to evaluate and predict design and operation of the Chashma Right Bank Canal

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    Irrigation systems / Irrigation canals / Flow control / Velocity / Canal regulation techniques / Hydraulics / Simulation models / Design / Operations / Crop-based irrigation / Distributary canals / Water delivery / Policy / Protective irrigation / Water allocation / Water requirements / Sedimentation / Water distribution / Equity / Water conveyance / Pakistan / Chashma Right Bank Canal

    Concurrent Dengue and Malaria infection: A Double Trouble

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    Platelet Satellitism: A Unique Cause of Pseudothrombocytopenia

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    Letter showing a unique report of platelet satellitis

    An Investigative Research Review of Traditions Seizing from Tafsir ul Qur’an by Sir Syed Ahmed Khan

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    Sir Syed Ahmad Khan was a versatile man who, perturbed about the future of the Muslims of sub- continent , had made struggles for the betterment of the sub-continental Muslims in every field. He made utmost efforts for enlightening muslims with the vistas of modern knowledge and mitigating the chasm between Islam and modern knowledge.He carried out several educational and pragmatic strides towards bringing the positive aspects of Islam and Islamic literature before the western world including a prominent milestone of " Tafseer Al-Quran" in which he tried to prove that Al-Quran is not averse to modern knowledge and answer the suspicions based on western philosophical thought vis a vis religious faith and theology through distinguish ways of exegesis in which Westernism and Mu'tazilatist school of thought seem to be prominent, deviating from the traditional methods of interpretation.On account of this, he tried to interpret Al-Quran on the basis of rational principles, making blips from muslims general belief. The purpose of this article is to exhibit the distinguished ways of author in "Tafseer Al-Quran" regarding derived narrations, take review of the takhreej of the narration methods ( Acceptance of narrations, Conjecturing,and Renouncing), and authenticity as well as methods of argumentation along with revealing the conjectured and renounced narrations in the light of Al-Quran, Ahadith and concrete arguments. In the end, the moot summary will be presented as the remaining part

    Children with lysinuric protein intolerance: Experience from a lower middle income country

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    BACKGROUND: Lysinuric protein intolerance (LPI) is an inborn error of metabolism consequential to recessive mutations in the SLC7A7 gene. The metabolic imbalance in absorption and excretion of dibasic amino acids is considered the basis of LPI. The disease results from protein intolerance with signs and symptoms oscillating from cerebral impairment, respiratory involvement, renal failure and autoimmune complications. AIM: To determine biochemical and clinical presentation of cases with biochemical picture suggestive of LPI in Pakistani children. METHODS: The study was conducted at the Biochemical Genetic Lab, Department of Pathology and Laboratory Medicine, AKU Plasma, and urine amino acid quantification data from January 2013 to October 2018 was included in this study. The amino acids were analyzed by high performance liquid chromatography. Prestructured requisition forms were used to obtain the clinicopathological data. Statistical analysis was done by Microsoft Excel 2017. RESULTS: A total of 6 patients were recognized. All the patients were male (100%). The mean age was 24 mo ± 10 d. All the patients had low plasma concentration of lysine, ornithine and arginine, whereas increased levels of lysine, ornithine and arginine in urine were observed in 2 patients. History of consanguineous marriage was present in all patients (100%). The most observed clinical symptom was feeding difficulty followed by failure to thrive (83.3%) and developmental delay (66.6%). Hepatomegaly was present in all patients (100%). No mutation analysis was done. CONCLUSION: This study portrays the biochemical and clinical spectrum of LPI in Pakistan. Although clinical manifestations appeared in the first 2 years of life, most of them suffered a delay in undergoing diagnostic workup
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