1,721,032 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The acute effects of mitochondrial targeted antioxidant on maximal oxygen uptake mechanics
No full textPurpose: To determine the acute effects of a mitochondrial targeting antioxidant (MitoQ) on cardiac output and maximal oxygen uptake during maximal exercise. We hypothesized that MitoQ would blunt maximal oxygen uptake independent of changes in cardiac output. Methods: Eight (N=8) apparently healthy adults (age 25±2.8 years and BMI 25.0±3.8 kg/m2) performed two trials (Placebo and MitoQ) in a double-blind randomized cross-over design. In both trials, participants performed 2 submaximal workloads on a cycle ergometer consisting of 3-minute stages immediately followed by an incremental exercise protocol until volitional exhaustion. Participants received either a Placebo or MitoQ (80mg) one hour prior to beginning the exercise protocol. Indirect calorimetry, blood pressure, heart rate, stroke volume, cardiac output, RPE, and oxygen saturation were collected throughout the duration of the exercise bout. Results: Maximal absolute, relative, and relative to lean mass VO2 was higher (p0.05). Conclusion: Consistent with our previous work, an acute dose of a mitochondrial targeted antioxidant blunted maximal absolute, relative, and relative to lean mass VO2. The reduction in VO2max does not appear to be related to blunted cardiac output, suggesting peripheral mechanisms underlie the lower oxygen utilization. Further, MitoQ improved work efficiency (VO2 per watt) at maximal exercise levels regardless of blunted oxygen uptake. Further research is warranted to examine the peripheral mechanism by which VO2 is blunted, and oxygen uptake efficiency is improved during maximal exercise.M. S
Age and muscle function : impact of aerobic exercise
No full textThe purpose of this investigation was to comprehensively examine the influence of progressive aerobic exercise training on whole muscle size and function in older women (65-80 yr). Three sedentary, healthy, females (66±1 yrs, 167±2 cm, 70±7 kg) performed 12 weeks of supervised progressive cycle training (42 training sessions 3-4 sessions/week up to 80% HRR). Subjects were tested before and after training for maximum aerobic capacity (VO2max), quadriceps cross sectional area (CSA), whole muscle specific tension, concentric 1-RM, maximum voluntary contraction (MVC), and concentric peak power (wafts). On average, the three subjects improved VO2max (34%), quadriceps CSA (10%), MVC (37%), whole muscle specific tension (25%), and concentric peak power (19%). These positive changes indicate that aerobic exercise may positively influence muscle size and function in the elderly.Thesis (M.S.)School of Physical Education, Sport, and Exercise Scienc
The benefits of a proposed exercise program for populations living with mental retardation : [an honors thesis (HONRS 499)]
No full textThe benefits of physical activity and exercise have been the topic of research for decades. With the variety of results supporting the importance of exercise in the general population, research needs to be conducted to discover whether exercise provides the same benefits for the mentally retarded population. A review of past research was conducted in order to develop and propose a program for understanding the benefits of various types of exercise. The benefits of conducting the proposed research is also discussed along with any limitations that apply.Thesis (B.?.)Honors Colleg
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
The effects of acute antioxidant suppmentation on metabolic responses to exercise
No full textTo determine the effects of an acute dosage of a mitochondrial targeting antioxidant on substrate utilization during exercise in physically inactive females. We hypothesized that an acute dosage would enhance the metabolic flexibility of these individuals. Methods: Nine (n=9) physically inactive females (age 47±22 years and BMI 28.5±3.8 kg/m2) performed two trials (Placebo and MitoQ) in a double-blind randomized cross-over design. In both trials, participants performed a submaximal workload consisting of three-minute stages until an RER of 1.0 was reached followed by an incremental exercise protocol until volitional exhaustion. Participants received either a Placebo or MitoQ (80mg) dosage one hour prior to beginning the exercise protocol. Indirect calorimetry, blood pressure, heart rate, RPE, and lactate were collected throughout the duration of the exercise bout. Results: The acute
antioxidant dosage had no effect on submaximal VO2,VCO2, substrate utilization, or cardiovascular response to exercise (p>0.05). During the maximal exercise portion VO2max was higher (p=0.03) during Placebo (23.5±5.7 mL/kg/min) compared to MitoQ (21.0±6.6 mL/kg/min). Maximal ventilation was also higher (p=0.02) in the Placebo (82.4±17.7 L/min) compared to MitoQ (75.0±16.8 L/min). Maximal breathing frequency was not different (p>0.05) between Placebo (44.9±7.0 Br/min) and MitoQ (43.6±5.0 Br/min) whereas maximal tidal volume was higher (p=0.02) between the Placebo (1.97±0.35 L(btps)/min) and MitoQ (1.83±0.40 L(btps)/min). Conclusion: An acute dose of a mitochondrial targeted antioxidant blunted VO2max, primarily mediated by inhibition of ventilatory function. These data suggest that the exogenous antioxidants lowered the accumulation of reactive oxygen species (ROS), thus causing a decrease in redox signaling capabilities, apparently impairing tidal volume. Further research is warranted on the ROS-antioxidant cell signaling cascades, and how they relate to optimizing mitochondrial function during exercise.M. S
The effects of a novel model of care on acute and long-term readmission rates in heart failure patients
No full textPurpose: Heart Failure (HF) is a chronic condition impacting millions of
Americans. The burden of HF has intensified and negatively impacts the economy and
society’s overall health and well-being. The purpose of this project is to examine the
effectiveness of this novel cardiac rehabilitation program as a core for HF management
in reducing acute and long-term readmission rates and improving patient care. Methods:
Indiana University Ball Memorial Hospital has implemented a guideline-directed
interdisciplinary HF model of care with cardiac rehabilitation as the central focus. The
model’s components aim to improve care transitions, enhance self-management and selfefficacy
of the patient, and improve patient outcomes through cardiac rehabilitation and
the use of the HF mini-order set. Data collection occurred from January 2023 through
December 2023 through electronic medical records (EMR) and Cerner to determine
readmission rates. Results: All-cause 30-day readmission monthly rates of patients who
participated in the model of care averaged 16.92 ± 9.12% in 2023. Long-term readmission
rates since the establishment of the model of care in 2016 averaged <1% and were <1%
for each month during 2023. Total Blue Dollar Savings using the Heart and Lung Center
(HLC) and the Mobile Integrated Health (MIH) Community Paramedic team was
~1,689,600, and the MIH Community Paramedic
team saved ~$1,241,600 in 2023. Conclusion: Blue Dollar Savings and improved
readmission rates in 2023 reflected the utilization of progressive care components,
guideline medical-directed therapies, and cardiac rehabilitation as a central core
component could be a cost-effective and care-effective solution. The multidisciplinary
progressive HF model of care provides valuable insight for healthcare providers,
policymakers, and researchers seeking to implement effective models of care to improve
patient outcomes.M. S
Effects of short-term intensified training on molecular factors related to myofiber regulation
No full textAccess to thesis permanently restricted to Ball State community onlyAccess to abstract permanently restricted to Ball State community onlyThesis (M.S.)School of Physical Education, Sport, and Exercise Scienc
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