90 research outputs found
Developing a Training System for Web Fires [video]
No full textTechCon2017 (CRUSER)Presented by LCDR Dan DeCicco, USN and NPS SEA 25 TDSI Cohort: Ryan Beall, Preston Tilus, Clayton Petty, Dor Kronzilber, Ang Chin Beng, Ang Pak Siang, Kan Wei Sheng, Ang Wee Kiong, Hoon Dingyao, Gay Wee Choon, Soh Yuan Wei, Yee Jian Hong, Ang Cheng Hai, Han Keng Siew, Foo Yueng Hao, Chin Hon Keong, See Hongze, Toh Ying Jie, Lai Wee, Tan Choon SengIncludes slidesSEA 25 TASKING: Design a fleet system of systems and concept of operations for employment of a cost effective training system capable of preparing naval warfighters to employ and leverage the web fires concepts and technologies in the 2025-2030 timeframe. Consider training across warfare specialties and missions; Conduct research to provide a solid foundation of knowledge requirements for a web fires fleet concept; Complete a gap analysis by comparing current fleet training with the required training to leverage cross domain and cross-platform capabilities in a warfighting environment; Scan for current examples of cross-domain training and current training simulation from DoD and industry; Develop a system architecture addressing responsible command, training requirements, training and exercise venues, and training participants to fill discovered gaps in meeting the knowledge requirements; Assess the proposed system against the principles of high velocity learning found in the CNO's "A Design for Maintaining Maritime SuperiorityNPS CRUSE
新加坡初级学院学生华文作文词语编误研究 = An error analysis of Chinese vocabulary usage in composition by junior college students in Singapore
No full textThe primary aim of this study is to investigate the trend and profile of different categories of improper vocabulary usage in Chinese composition by students from 14 junior colleges in Singapore. This study, in presenting and analysing the various error categories and contributory causes, provides for consideration some proposals to arrest and correct the errors committed by students. It is hoped that the findings of this study would be of contribution to Chinese Language teachers in their classroom teaching as well as to textbook writers in their devising of instructional materials.Master of Art
"I' ll tell you a story that will make you believe" in narratives: the role of metafiction in the novel and in the film Life of Pi
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Inglês: Estudos Linguísticos e Literários, Florianópolis, 2015.Recentes estudos propõem que adaptações cinematográficas sejam entendidas como fonte de criação, os quais refletem contextos e interpretações diferentes do texto em que são baseadas. Nessa dissertação, propõe-se uma análise comparativa do romance Life of Pi (2001), de Yann Martel e do filme homônimo dirigido por Ang Lee (2012). A análise tem como objetivo identificar a presença e o modo em que a metaficção é construída no romance e no filme, e quais são alguns significados produzidos por ela em ambos os textos, tanto o literário quanto o fílmico. A concepção de metafição se baseia nas definições de Linda Hutcheon e Patricia Waugh. Por metaficção, entende-se a ficção consciente de si, que expõe o processo de escrita ao leitor e o convida a ter um papel ativo na construção do significado. Após uma análise comparativa dos dois textos, conclui-se que a metaficção está presente em ambos, tanto tematicamente como estruturalmente. As reflexões sobre narrativas apresentadas pelos personagens, o uso de vários níveis narrativos e de intertextualidade revelam diferentes usos da metafição em ambos. A diferença mais importante entre o romance e o filme Life of Pi está no uso dos níveis narrativos. Enquanto o romance possui um ?autor? sem nome que apresenta a história aos leitores, o filme possui um diretor implícito que deixa pistas de qual versão da história de Pi é ?real? no contexto da narrativa. Essa diferença dá ao romance um final aberto, em que o leitor deve escolher qual versão da história ele acredita, enquanto o filme possui uma resolução para essa questão. O filme, então, pode ser entendido como um testemunho, uma narrativa de trauma de um sobrevivente de um naufrágio e da experiência de migração, enquanto o livro não apresenta uma decisão em relação às versões da história, deixando o leitor aberto a qualquer possibilidade.Abstract : Recent studies propose that Film Adaptations should be understood as sources of creation, which also reflect a different context and interpretation from the text upon which they were based. In this thesis, I propose a comparative analysis of the novel Life of Pi (2001), by Yann Martel, and the homonymous film directed by Ang Lee (2012). The analysis has the objective of identifying the presence and the way in which metafiction is constructed in the novel and in the film, and what are some of the meanings produced by it in both texts, the filmic and the literary. The concept of metafiction was based on the definitions by Linda Hutcheon and Patricia Waugh. It is understood as the self-conscious fictional text, which exposes the writing process to the readers and invites them to have an active role in the construction of meaning. In the comparative analyses of the two texts, I have proved that metafiction is present in the two texts, both thematically and structurally. The reflections of the characters on narrative itself as well as the use of different narrative levels and intertextual references reveal different uses of metanarrative in both film and novel. The most important difference between the novel and the film Life of Pi is in their uses of different narrative levels. While the novel has an unnamed =author? who presents the story to the readers, the film has an implicit director who leaves =clues? of which version of Pi?s story is ?real? in the context of the narrative. This difference gives to the novel an open end, facein which the readers must choose which version of the story they believe in, while the film presents a resolution to this question. The film, thus, can be understood as a testimony narrative, a narrative of the trauma of a survivor from a shipwreck and from the experience of migration, while the novel does not decide for one of the versions of the story, enabling a more inconclusive reading
Zuo shi bai chuan xue hai
No full text[v.1]. 聖門事業圖 -- 漁樵對問 / 邵雍 -- [v.2]. 九經補韻 / 楊伯喦 -- 宜齋野乘 / 吳枋 -- 芥隠筆記 / [龔頤正] -- 因話錄 / 趙璘 -- 翰林志 / 李肇 -- [v.3]. 玉匣記 / 皇甫牧 -- 杼情錄 / 盧懷 -- 揮塵錄 / 王清臣 -- 丁晋公談錄 / 丁謂 -- 王文正筆錄 / 王曾 -- 傳信記 / 鄭棨 -- 尚書故實 / 李綽 -- [v.4]. 柳氏舊聞 / 李德裕 -- 錢氏私誌 / 錢世昭 -- 家世舊聞 / 陸游 -- 默記 / 王銍 -- 卓異記 / 李翱 -- 艮嶽記 / 張淏 -- [v.5]. 晝簾緖論 / 胡大初 -- 官箴 / 呂居仁 -- 袪疑說 / 儲泳 -- [v.6]. 王氏談錄 / 王洙 -- 宋景文公筆記 / 宋祁 -- [v.7]. 善誘文 / 陳錄 -- 西疇老人常言 / 江河垣 -- 欒城先生遺言 / 蘇籀 -- 東谷所見 / 李之彥 -- [v.8]. 雞肋 / 趙崇絢 -- 畫墁錄 / 張舜民 -- 碧雲騢 / 梅堯臣 -- 霏雪錄 / 孟熙 -- [v.9]. 談藪 / 龎元英 -- 話腴 / 陳郁 -- 可談 / 朱或 -- 前定錄 / 鍾輅 -- 拊掌錄 / 元懷 -- [v.10]. 山房隨筆 / 蔣子正 -- 文錄 / 唐庚 -- 石林詩話 : [三卷] / 葉夢得 -- 六一居士詩話 / 歐陽修.[v.11]. 庚溪詩話 / 西郊野叟 -- 劉攽貢父詩話 / 劉攽 -- 後山居士詩話 / 陳師道 -- 彥周詩話 / 許顗 -- [v.12]. 司馬温公詩話 / 司馬光 -- 竹坡老人詩話 / 周少隱 -- 滄浪詩話 / 嚴羽 -- [v.12-13]. 書史 : [二卷] / 陽米芾 -- [v.13]. 書斷 : 四卷 / 張懷瓘 -- 書評 / 袁昂 -- 書譜 / 孫過庭 -- 續書譜 / 姜堯章 -- [v.14]. 海岳名言 / 陽米芾 -- 寶章待訪錄 / 陽米芾 -- 翰墨志 / 宋高宗 -- 法帖刊誤 : [二卷] / 黃伯思 -- 譜系雜說 : [二卷] / 曹士冕 -- 歐公試筆 / 歐陽修 -- [v.15]. 古畫品錄 / 謝赫 -- 後畫品錄 / 姚最 -- 畫品 / 李廌 -- 畫論 / 湯垕 -- 畫論 / 郭思 -- 紀藝 / 郭思 -- 林泉高致 / 郭熙 -- 硯譜 / 李之彥 -- 硯史 / 陽米芾 -- [v.16]. 端溪硯譜 / 葉樾 -- 歙硯說 / 曹繼善 -- 辨歙石說 / 曹繼善 -- 香譜 / 洪芻 -- 茶經 : [三卷] / 陸羽 -- [v.17]. 茶錄 / 蔡襄 -- 試茶錄 / 宋子安集 -- 酒譜 / 竇革 -- 茘枝譜 / 蔡襄 -- 橘錄: [三卷] / 韓彥直 -- [v.17-18]. 南方草木狀 : [三卷] / 晋譙國.[18]. 竹譜 / 戴凱之 -- 梅譜 / 范成大 -- 金漳蘭譜 / 趙時庚 -- 蔬食譜 / 陳達叟 -- 梅品 / 張功甫 -- 洛陽牡丹記 / 歐陽脩 -- 天彭牡丹譜 / 陸游 -- 牡丹榮辱志 / 丘璩 -- 楊州芍藥譜 / 王觀 -- 海棠譜 / 陳思 -- 菊譜 / 劉蒙 -- [v.19]. 菊譜 / 史正志 -- 蟹譜 : [二篇] / 傅肱 -- 禽經 / 張華 -- 相鶴經 / 浮丘公 -- 相牛經 / 寗戚 -- 耒耜經 / 陸龜蒙 -- 洛陽名園記 / 李廌 -- 岳陽風土記 / 范致明 -- [v.20]. 眞臘風土記 / 周達觀 -- 桂海巖洞志 / 范成大 -- 杜海香志 / 范成大 -- 桂海酒志 / 范成大 -- 桂海器志 / 范成大 -- 桂海禽志 / 范成大 -- 桂海獸志 / 范成大 -- 桂海蟲魚志 / 范成大 -- 桂海花志 / 范成大 -- 桂海果志 / 范成大 -- 桂海草木志 / 范成大 -- 桂海雜志 / 范成大 -- 桂海蠻志 / 范成大 -- 洞天福地記 / 杜光庭.[v.1]. Sheng men shi ye tu -- Yu qiao dui wen / Shao yong -- [v.2]. Jiu jing bu yun / Yang Boyan -- Yi zhai ye cheng / Wu Fang -- Jie yin bi ji / [Gong Yizheng] -- Yin hua lu / Zhao Lin -- Han lin zhi / Li Zhao -- [v.3]. Yu xia ji / Huang Fumu -- Zhu qing lu / Lu Huai -- Hui chen lu / Wang Qingchen -- Ding jin gong tan lu / Ding Wei -- Wang wen zheng bi lu / Wang Zeng -- Zhuan xin ji / Zheng Qi -- Shang shu gu shi / Li Chuo -- [v.4]. Liu shi jiu wen / Li Deyu -- Qian shi si zhi / Qian Shizhao -- Jia shi jiu wen / Lu You -- Mo ji / Wang Zhi -- Zhuo yi ji / Li Ao -- Gen yue ji / Zhang Hao -- [v.5]. Zhou lian xu lun / Hu Dachu -- Guan zhen / Lü Juren -- Qu yi shuo / Chu Yong -- [v.6]. Wang shi tan lu / Wang Zhu -- Song jing wen gong bi ji / Song Qi -- [v.7]. Shan you wen / Chen Lu -- Xi chou lao ren chang yan / Jiang Heyuan -- Luan cheng xian sheng yi yan / Su Zhou -- Dong gu suo jian / Li Zhiyan -- [v.8]. Ji lei / Zhao Chong xuan -- Hua man lu / Zhang Shunmin -- Bi yun xia / Mei Yaochen -- Fei xue lu / Meng Xi -- [v.9]. Tan sou / Pang Yuanying -- Hua yu / Chen Yu -- Ke tan / Zhu Huo -- Qian ding lu / Zhong Lu -- Fu zhang lu / Yuan Huai -- [v.10]. Shan fang sui bi / Jiang Zizheng -- Wen lu / Tang Geng -- Shi lin shi hua : [san juan] / Ye Mengde -- Liu yi ju shi shi hua / Ouyang Xiu.[v.11]. Geng xi shi hua / Xijiao Yesou -- Liu ban gong fu shi hua / Liu Ban -- Hou shan ju shi shi hua / Chen Shidao -- Yan zhou shi hua / Xu Yi -- [v.12]. Si ma wen gong shi hua / Sima Guang -- Zhu po lao ren shi hua / Zhou Shaoyin -- Cang lang shi hua / Yan Yu -- [v.12-13]. Shu shi : [er juan] / Yang Mifei -- [v.13]. Shu duan : si juan / Zhang Huaiguan -- Shu ping / Yuan Ang -- Shu pu / Sun Guoting -- Xu shu pu / Jiang Yaozhang -- [v.14]. Hai yue ming yan / Yang Mifei -- Bao zhang dai fang lu / Yang Mifei -- Han mo zhi / Song Gaozong -- Fa tie kan wu : [er juan] / Huang Bosi -- Pu xi za shuo : [er juan] / Cao Shimian -- Ou gong shi bi / Ouyang Xiu -- [v.15]. Gu hua pin lu / Xie He -- Hou hua pin lu / Yao Zui -- Hua pin / Li Zhi -- Hua lun / Tang Hou -- Hua lun / Guo Si -- Ji yi / Guo Si -- Lin quan gao zhi / Guo Xi -- Yan pu / Li Zhiyan -- Yan shi / Yang Mifei -- [v.16]. Duan xi yan pu / Ye Yue -- Xi yan shuo / Cao Jishan -- Bian xi shi shuo / Cao Jishan -- Xiang pu / Hong Chu -- Cha jing : [san juan] / Lu Yu -- [v.17]. Cha lu / Cai Xiang -- Shi cha lu / Song Zian ji -- Jiu pu / Dou Ge -- Li zhi pu / Cai Xiang -- Ju lu: [san juan] / Han Yanzhi -- [v.17-18]. Nan fang cao mu zhuang : [san juan] / Jin Qiaoguo.[18]. Zhu pu / Dai Kaizhi -- Mei pu / Fan Chengda -- Jin zhang lan pu / Zhao Shigeng -- Shu shi pu / Chen Dasou -- Mei pin / Zhang Gongfu -- Luo yang mu dan ji / Ouyang Xiu -- Tian peng mu dan pu / Lu You -- Mu dan rong ru zhi / Qiu Qu -- Yang zhou shao yao pu / Wang Guan -- Hai tang pu / Chen Si -- Ju pu / Liu Meng -- [v.19]. Ju pu / Shi Zhengzhi -- Xie pu : [er pian] / Gu Gong -- Qin jing / Zhang Hua -- Xiang he jing / Gu Qiugong -- Xiang niu jing / Ning Qi -- Lei si jing / Lu Guimeng -- Luo yang ming yuan ji / Li Zhi -- Yue yang feng tu ji / Fan Zhiming -- [v.20]. Zhen la feng tu ji / Zhou Daguan -- Gui hai yan dong zhi / Fan Chengda -- Du hai xiang zhi / Fan Chengda -- Gui hai jiu zhi / Fan Chengda -- Gui hai qi zhi / Fan Chengda -- Gui hai qin zhi / Fan Chengda -- Gui hai shou zhi / Fan Chengda -- Gui hai chong yu zhi / Fan Chengda -- Gui hai hua zhi / Fan Chengda -- Gui hai guo zhi / Fan Chengda -- Gui hai cao mu zhi / Fan Chengda -- Gui hai za zhi / Fan Chengda -- Gui hai man zhi / Fan Chengda -- Dong tian fu di ji / Du Guangting.[左圭輯].綫裝, 2函.框19.1x14.3公分, 9行20字, 小字雙行同, 白口, 單白魚尾, 左右雙邊, 版心上鐫小題, 下鐫葉次.版式據《九經補韻》卷一.分甲, 乙, 丙, 丁, 戊, 巳, 庚, 辛, 壬, 癸集.原為"借月山房"本?Xian zhuang, 2 han.Kuang 19.1 x 14.3 gong fen, 9 hang 20 zi, xiao zi shuang hang tong, bai kou, dan bai yu wei, zuo you shuang bian, ban xin shang juan xiao ti, xia juan ye ci.Ban shi ju "Jiu jing bu yun" juan yi.Fen jia, yi, bing, ding, wu, si, geng, xin, ren, gui ji.Yuan wei "Ji yue shan fang" ben?[Zuo Gui ji]
A security strategy for cyber threats on neighbor discovery in 6LoWPAN networks
No full textReissued 27 Sep 2018 to reflect updated abstract on pages i and v.Wireless sensor networks (WSNs) employ various technologies to facilitate low power communications. One such technology is the Internet Protocol version 6 (IPv6) Low Power Local Area Networks (6LoWPAN). One of the key concerns for 6LoWPAN networks is the vulnerability of its neighbor discovery (ND) protocol. In this thesis, we study the potential threat vectors against the ND protocol, focusing specifically on replay attacks that can cause denial of service (DoS). We propose a combination of hard and soft security approaches to mitigate cyber-attacks against the ND protocol. The hard security approach is based on a Trust-ND option, which includes a Timestamp, Nonce, and SHA-1 hashing function. The soft security approach leverages the social interactions between the nodes in the network to identify malicious nodes. We also propose a time-synchronization mechanism to synchronize the local clock of the nodes in the network. We demonstrate the effectiveness of the Nonce and Timestamp functions against replay attacks using the Contiki Operating System (OS) and Cooja network simulator. Via simulations, we also demonstrate the effectiveness of the time-synchronization mechanism. In addition, the data captured during the simulations is further analyzed using Wireshark.Approved for public release; distribution is unlimited.Civilian, Defence Science and Technology Agency (DSTA)http://archive.org/details/asecuritystrateg109455674
Pelliot chinois 3619
No full textDao yi pian 擣 衣 篇Contient : Recueil de poèmes des Tang ; Qing ming ri deng Zhang nü lang shen 青 (淸) 明 日 登 張 女 郎 神 par Su Jie 蘇 ; Bao jian pian 寶 劍 篇 par Guo Yuan zhen 郭 元 振 ; Si ma fu 死 馬 賦 par Liu Xi yi 劉 希 移 (逸) ; Bai tou weng 白 頭 翁 par Liu Xi yi ; Bei Mang pian 北 邙 篇 [par Liu Xi yi] ; Dao yi pian 擣 衣 篇 par Liu Xi yi ; Deng huang he lou 登 黃 鶴 樓 par Cui Hao 崔 顥 ; Deng guan que lou 登 觀 鵲 樓 par Chang Zhu 暢 諸 ; Deng Ji zhou cheng lou 登 岐 州 城 樓 par Huang fu Bin 皇 甫 斌 ; Du Da yu ling 度 大 臾 (禹) 嶺 par Song Zhi wen 宋 之 問 ; Yang zi jiang ye an 揚 子 江 夜 宴 par Cai Xi ji 蔡 希 寂 ; Cai yun pian 彩 雲 篇 par Li Yong 李 邕 ; Du Ba xia 度 巴 硤 [par Li Yong] ; Poème sans titre, [par Li Yong] ; Ye He shang gong miao 謁 河 上 公 廟 par Zu Yong 祖 詠 ; Chi jie Qi wang jiu cheng gong bi shu 勅 借 岐 王 九 城 宮 避 暑 par Wang Wei 王 維 ; Jiu yue jiu ri deng gao 九 月 九 日 登 高 par Gao Shi 高 適 ; Da tong jun xing 大 桐 軍 行 par Li Bin 李 斌 ; Poème sans titre, par Song Zhi wen ; Deng Ling yan si 登 靈 巖 寺 par le śramaṇa Ri jin 日 進 ; Ye sheng rong 謁 聖 容 par Hun Wei ming 渾 維 明 ; Zao xing Dong jing 早 行 東 京 [par Hun Wei ming] ; Cai lian pian 採 蓮 篇 [par Hun Wei ming] ; Tu fan dang she ren lin xing 吐 蕃 黨 舍 人 臨 刑 [par Hun Wei ming ; Jian ge 劍 歌 par Li Bin ; Ri nan wang 日 南 王 ; You yuan 遊 菀 par Su Jie ; Po zhen yue 破 陣 樂 par Ge shu Han 歌 舒 翰 ; Yan zhi xing guan 燕 支 行 管 par Cui Xi yi 崔 希 逸 ; Poème sans titre, par Gao Shi ; Xiao zhao 簫 沼 ; Ye du Ying shui 夜 渡 穎 水 par Li Bin ; Qian gu ren 餞 故 人 par Gao Shi ; Qiu ye 秋 夜 par Xuan Yu 桓 顒 ; Shu huai 述 懷 de Shi Ang 史 昂 ; Tan Su Wu Bei hai 歎 蘇 武 北 海 [par Shi Ang ; Ye wai yao zhan Hun jiang jun 野 外 遙 占 渾 將 軍 [par Shi Ang ; 7 fragments d'une liste de religieuxNumérisation effectuée à partir d'un document original
Predicting fish assemblages and diversity in shallow lakes in the Yangtze River basin
No full textHabitat modifications induced by humans severely impact biotic components of freshwater ecosystems. In China, shallow lakes in the Yangtze River basin are facing severe habitat degradation induced by pollution, habitat losing, macrophytes disappearing and fishery activities. Effectively modeling the fish communities on the basis of biotic and abiotic environmental descriptors would be helpful to understand the relationships between fish and their environment, and to develop suitable conservation strategies to sustain the biodiversity in these ecosystems. From 2007 to 2009, investigations were carried out on fish and their environment in 6 lakes distributed in the mid-reach of the Yangtze River basin. According to the CPUE values of each fish species from each sampling, 117 datasets were ordinated using self-organizing map (SOM). Fish communities were classified into three clusters of species assemblages, spatial and temporal distributions were showing in it. Seasonal changes in fish community were more obvious in vegetated habitats than in unvegetated areas. The total CPUE, fish diversity and species richness were significantly different among the assemblages (p < 0.01). Based on the indicative value of each species in each cluster calculated by Indval method, 16 species were identified as indicators: 13 indicators in cluster G1 are pelagic or benthopelagic fish, the only one indicator species in G2 is a tolerant species (Culter dabry B.), while the other two indicator species in G3 are demersal fish (Rhinogobius giurinus R. and Odontobutis obscurus T. & G.). These results are in agreement with the contributions of different ecological groups of fish in each assemblage in the trained SOM, pelagic and benthopelagic fish were found having more activities in spring and winter, while more activities of demersal fish were found in summer and autumn. Fish community assemblages, the total fish CPUE, diversity and species richness in those lakes were then predicted by 15 abiotic and biotic factors using random forest (RF) and classification and regression tree (CART) predictive models. The predicted assignment of each site unit to the correct assemblage had an average success of 74.4% and 60.7% in RF and CART models, respectively. The dominant variables for discriminating three fish assemblages were water depth, distance to the bank and total phosphorus. While the two important variables in prediction fish CPUE, diversity and species richness were lake surface area and water depth, density of rotifer and water depth, water depth and water temperature, respectively. The overall percentages of successful prediction varied from 56.5% to 67% utilizing leave-one-out for cross-validation tests. (C) 2011 Elsevier GmbH. All rights reserved.Habitat modifications induced by humans severely impact biotic components of freshwater ecosystems. In China, shallow lakes in the Yangtze River basin are facing severe habitat degradation induced by pollution, habitat losing, macrophytes disappearing and fishery activities. Effectively modeling the fish communities on the basis of biotic and abiotic environmental descriptors would be helpful to understand the relationships between fish and their environment, and to develop suitable conservation strategies to sustain the biodiversity in these ecosystems. From 2007 to 2009, investigations were carried out on fish and their environment in 6 lakes distributed in the mid-reach of the Yangtze River basin. According to the CPUE values of each fish species from each sampling, 117 datasets were ordinated using self-organizing map (SOM). Fish communities were classified into three clusters of species assemblages, spatial and temporal distributions were showing in it. Seasonal changes in fish community were more obvious in vegetated habitats than in unvegetated areas. The total CPUE, fish diversity and species richness were significantly different among the assemblages (p < 0.01). Based on the indicative value of each species in each cluster calculated by Indval method, 16 species were identified as indicators: 13 indicators in cluster G1 are pelagic or benthopelagic fish, the only one indicator species in G2 is a tolerant species (Culter dabry B.), while the other two indicator species in G3 are demersal fish (Rhinogobius giurinus R. and Odontobutis obscurus T. & G.). These results are in agreement with the contributions of different ecological groups of fish in each assemblage in the trained SOM, pelagic and benthopelagic fish were found having more activities in spring and winter, while more activities of demersal fish were found in summer and autumn. Fish community assemblages, the total fish CPUE, diversity and species richness in those lakes were then predicted by 15 abiotic and biotic factors using random forest (RF) and classification and regression tree (CART) predictive models. The predicted assignment of each site unit to the correct assemblage had an average success of 74.4% and 60.7% in RF and CART models, respectively. The dominant variables for discriminating three fish assemblages were water depth, distance to the bank and total phosphorus. While the two important variables in prediction fish CPUE, diversity and species richness were lake surface area and water depth, density of rotifer and water depth, water depth and water temperature, respectively. The overall percentages of successful prediction varied from 56.5% to 67% utilizing leave-one-out for cross-validation tests. (C) 2011 Elsevier GmbH. All rights reserved
Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and Dysfunction
No full text
The apelin pathway has emerged as a critical regulator of cardiovascular homeostasis and disease. However, the exact role of pyr1-apelin-13 in angiotensin (Ang) II–mediated heart disease remains unclear. We used apelin-deficient (APLN
−/y
) and apolipoprotein E knockout mice to evaluate the regulatory roles of pyr1-apelin-13. The 1-year aged APLN
−/y
mice developed myocardial hypertrophy and dysfunction with reduced angiotensin-converting enzyme 2 levels. Ang II infusion (1.5 mg kg
−1
d
−1
) for 4 weeks potentiated oxidative stress, pathological hypertrophy, and myocardial fibrosis in young APLN
−/y
hearts resulting in exacerbation of cardiac dysfunction. Importantly, daily administration of 100 μg/kg pyr1-apelin-13 resulted in upregulated angiotensin-converting enzyme 2 levels, decreased superoxide production and expression of hypertrophy- and fibrosis-related genes leading to attenuated myocardial hypertrophy, fibrosis, and dysfunction in the Ang II–infused apolipoprotein E knockout mice. In addition, pyr1-apelin-13 treatment largely attenuated Ang II–induced apoptosis and ultrastructural injury in the apolipoprotein E knockout mice by activating Akt and endothelial nitric oxide synthase phosphorylation signaling. In cultured neonatal rat cardiomyocytes and cardiofibroblasts, exposure of Ang II decreased angiotensin-converting enzyme 2 protein and increased superoxide generation, cellular proliferation, and migration, which were rescued by pyr1-apelin-13, and Akt and endothelial nitric oxide synthase agonist stimulation. The increased superoxide generation and apoptosis in cultured cardiofibroblasts in response to Ang II were strikingly prevented by pyr1-apelin-13 which was partially reversed by cotreatment with the Akt inhibitor MK2206. In conclusion, pyr1-apelin-13 peptide pathway is a negative regulator of aging-mediated and Ang II–mediated adverse myocardial remodeling and dysfunction and represents a potential candidate to prevent and treat heart disease.
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Developing computational thinking through coding
No full textThis paper was presented at the 20th Asian Technology Conference in Mathematics, held in Leshan, China from 16 – 20 December 2015The turn of the 21st Century sees renewed emphasis on STEM (Science, Technology, Engineering and Mathematics). Building a Smart Nation is now a buzzword for many developed countries. Compelled by the advancement of information and communication technology, the ability to code in a programming language is a skill that is now, more than ever, urgently called for. In addition, it is widely believed that coding enhances problem solving abilities. In this paper, by underscoring the disciplinarity of coding, we construct a curricular framework for inculcating computational thinking in authentic classroom situations. Our proposition that computational thinking can only be imparted through doing, and this is supported by episodes of a graduate course, taught by the second author, in which graduate students develop coding competencies in vba.Published versio
Caveolae in smooth muscle cells mediates vasoconstriction of renal artery in rats
No full textObjective To investigate the role of caveolae on vascular smooth muscle cells(VSMCs)in vasoconstriction of renal artery(RA)and the possible mechanisms.Methods The RA was pretreated with methyl-beta-cyclodextrin(MCD)and cholesterol(CHO)to reduce and enhance the formation of caveolae,respectively.Isometric force recording system was used to detect the vascular function.Real-time polymerase chain reaction(RT-PCR) and Western blotting were conducted to examine the expression of mRNA and protein of caveolin-1 and Angiotensin type 1 receptor(AT1R).Immumoprecipitation with Western blotting was carried out to test the binding of caveolin-1 and AT1 R.Results Incubation with MCD reduced the caveolae number in VSMCs significantly(P<0.05),which could be reversed by CHO treatment.Neither the MCD nor CHO influenced the gene or protein expression of caveolin-1.The vasoconstriction of RA to KCl or PE did not change after MCD or CHO incubation.However,MCD could inhibit the vasoconstriction of the artery to Ang Ⅱ with lower Emax(P<0.05)and higher EC50(P<0.05),which again could be reversed by CHO pretreatment The protein expression of AT1 R was not affected by MCD or CHO incubation.In the case of normal RA,Ang Ⅱ would promote the binding of AT1 R to caveolin-1(P<0.05),while the response was blocked substantially in MCD-incubated RA,which was restored if the RA was treated by MCD and CHO simultaneously.Conclusions The caveolae regulate the vasoconstriction of RA to Ang Ⅱ by controlling the binding of caveolin-1 with AT1 R
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