1,920 research outputs found
Social and motivational functioning is not critically dependent on feedback of autonomic responses: neuropsychological evidence from patients with pure autonomic failure
No full textSocial, emotional and motivational behaviours are associated with production of automatic bodily responses. Re-representation in the brain through feedback of autonomic and skeletomuscular arousal is proposed to underlie "feeling states". These influence emotional judgments and bias motivational decision-making and guide social interactions. Consistent with this hypothesis, dissocial behaviour and deficits on emotional and motivation tasks are associated with blunted bodily responses in patients with orbitofrontal brain lesions or developmental psychopathy. To determine the critical dependence of social and emotional behaviours on bodily responses mediated by the autonomic nervous system, we examined patients with pure autonomic failure (PAF), a peripheral denervation of autonomic neurons with onset in middle age. Compared to healthy subjects, PAF patients were unimpaired on tests of motivational decision-making (Iowa Gambling Task), recognition of emotional facial expressions, Theory of Mind Tasks and tests of social cognition. Only on a test of emotional attribution, which is perhaps more sensitive to subjective feeling states, did PAF patients score worse than the comparison group, though there was no evidence that this deficit was specific to a discrete emotion and requires further validation. These findings suggest that emotional and social functioning is not critically tied to on-going experience of autonomic arousal state, Acquisition of autonomic failure late in life may protect against maladaptive social behaviour through established behavioural responses that may be associated with central "as if" representations
Cognitive functioning in orthostatic hypotension due to pure autonomic failure.
No full textPsychophysiological
science proposes close interactions
between cognitive processes and
autonomic responses, yet the consequences of autonomic failure on
cognitive functioning have not
been documented. This pilot study
investigates, for the first time, the
cognitive profile of 14 patients with
Pure Autonomic Failure (PAF).
Each patient was administered a
comprehensive battery of neuropsychological tests and neuroimaging investigation. A number
of patients (n = 6) presented with
cognitive impairment. The two
most frequent types of impairment
were: deficits of speed and attention, and executive functioning.
Impairments of free recall memory, intellectual functioning, nominal and calculation functions were
also documented, albeit in a much
lower frequency. These cognitive
changes were not always associated
with white matter abnormalities.
We speculate that the cognitive impairments associated with PAF represent consequences of systemic
hypotension with cerebral under-perfusion. However, a failure in integrated bodily arousal responses
during cognitive behaviours may
also contribute to some of the observed deficits
Observation of hc radiative decay hc › ??' and evidence for hc › ??
No full textKolcu, Onur Buğra (Arel Author) --- Makale 69 yazarlıdır.A search for radiative decays of the P-wave spin singlet charmonium resonance hc is performed based on 4.48 × 108 ? events collected with the BESIII detector operating at the BEPCII storage ring. Events of the reaction channels hc › ??' and ?? are observed with a statistical significance of 8.4? and 4.0?, respectively, for the first time. The branching fractions of hc › ??' and hc › ?? are measured to be B(hc › ??' ) = (1.52±0.27±0.29)×10-3 and B(hc › ??) = (4.7±1.5±1.4)×10-4 , respectively, where the first errors are statistical and the second are systematic uncertainties
Financial analysis and evaluation of company HC Betons Ltd
No full textDiplomdarba nosaukums: Uzņēmuma SIA HC Betons finanšu analīze un novērtējums
Diplomdarba mērķis ir uz finanšu analīzes pamata izvērtēt uzņēmuma SIA HC Betons esošo finansiālo situāciju un izstrādāt priekšlikumus finansiālā stāvokļa uzlabošanai.
Teorētiskajā daļā apskatīti finanšu analīzes teorētiskie aspekti. Praktiskajā daļā autore veica uzņēmuma SIA HC Betons finanšu analīzi par 2009., 2010., un 2011.gadu. Analītiskajā daļā autore salīdzina rādītājus ar konkurējošo uzņēmumu SIA Cemex.
Autore secinājusi, ka uzņēmumam ir finansiālas grūtības, bet pēc autores domām, uzņēmums tuvāko gadu laikā nebankrotēs.
Diplomdarba apjoms ir 78 lapaspuses, tas sastāv no 3 daļām, 12 tabulām, 5 attēliem un 12 pielikumiem.
Atslēgvārdi: analīze, likviditāte, bankrots, koeficienti.Diploma thesis: Financial Analysis and Evaluation of Company HC Betons Ltd.
The aim of the diploma paper is to evaluate company’s HC Betons Ltd current financial situation based on financial analysis and make suggestions for improvement of the financial position.
Theoretical aspects of financial analysis are discussed in the theoretical part of the paper. In the practical part author has performed company’s HC Betons Ltd financial analysis of the years 2009, 2010 and 2011. In the analytical part author compares ratios of a competing company Cemex Ltd.
The author concludes that the company is in financial difficulties, but according to the author’s thoughts, the company will not bankrupt in the coming years.
The volume of the diploma paper is 78 pages; it consists of 3 parts, 12 tables, 5 images and 12 appendices.
Keywords: analysis, liquidity, bankruptcy, ratios
Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies
No full textThe application of a 1H nuclear magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely available analgesics (acetaminophen and ibuprofen) in epidemiologic studies has been investigated. We used samples and data from the cross-sectional INTERMAP Study involving participants from Japan (n = 1145), China (n = 839), U.K. (n = 501), and the U.S. (n = 2195). An orthogonal projection to latent structures discriminant analysis (OPLS-DA) algorithm with an incorporated Monte Carlo resampling function was applied to the NMR data set to determine which spectra contained analgesic metabolites. OPLS-DA preprocessing parameters (normalization, bin width, scaling, and input parameters) were assessed systematically to identify an optimal acetaminophen prediction model. Subsets of INTERMAP spectra were examined to verify and validate the presence/absence of acetaminophen/ibuprofen based on known chemical shift and coupling patterns. The optimized and validated acetaminophen model correctly predicted 98.2%, and the ibuprofen model correctly predicted 99.0% of the urine specimens containing these drug metabolites. The acetaminophen and ibuprofen models were subsequently used to predict the presence/absence of these drug metabolites for the remaining INTERMAP specimens. The acetaminophen model identified 415 out of 8436 spectra as containing acetaminophen metabolite signals while the ibuprofen model identified 245 out of 8604 spectra as containing ibuprofen metabolite signals from the global data set after excluding samples used to construct the prediction models. The NMR-based metabolic screening strategy provides a new objective approach for evaluation of self-reported medication data and is extendable to other aspects of population xenometabolome profiling
Specific and fitness testing of goalies HC Motor Czech Budejovice\\
No full textThe aim of this bachelor thesis is to test specific and fitness abilities of goalkeepers of HC Motor Czech Budejovice. In the theoretical part of this thesis, based on content analysis of literature research, the author presents motoric abilities, development patterns and overview of most frequently used tests. In the practical part of thesis, the author deals with creating and verifying tested battery. It was designed using the knowledge gained from books reference and self- experience of a player and a coach as well. To obtain the results of performance of particular motoric abilities the author used testing method. The outcomes were subsequently compared with the evaluation of given motoric abilities on ice. The author acquired the evaluation from goalkeeper's coaches of HC Motor Czech Budejovice. Final results are described and thereafter tabularly presented
VIBRATIONAL RELAXATION IN THE BINARY GASEOUS MIXTURES AND
No full textAuthor Institution: Laboratoire de Spectronomie Moleculaire, Universit\'e de Paris VI, 4, Place Jussieu - Tour 13Vibrational relaxation rates for gaseous mixtures , with or , in which vibrational energy transfer can occur from the level of M to the v = 1 level of , has been measured as a function of the temperature using the laser-induced vibrational fluorescence technique. The relaxation processes which must be considered are: - the V-V transfer process: \begin{eqnarray*} &&M(00^{\circ }1)+ HC (v=0)\begin{array}{c}^{k}M-HC\ell\\ \rightleftharpoons\\ ^{k}HC\ell-M\end{array}M(00^{\circ}0)+ HC\ell(v=1)+ \Delta E=he\Delta\nu\\ &&with\ \Delta\nu=-537\, cm^{-1} for\ CO_{2}, -663\, cm ^{-1}\ for\ N_{2}O \end{eqnarray*} - the V-TR de-excitation processes: \begin{eqnarray*} M(00^{\circ}1)+ HC\ell(or M)\stackrel{k^{HC\ell}_{M}}{(o\vec{r}\; k_{M})}M(mn^{\ell}0)+HC\ell (or \; M)\\ HC\ell(v=1)+ M(or\; HC\ell)\stackrel{k^{M}_{HC\ell}}{(o\vec{r}\; k_{HC\ell})}HC\ell(v=0)+M(or \; HC\ell) \end{eqnarray*} For most of the systems in which near-resonant V-V transfers occur, the V-TR de-excitation rates are negligible compared to the V-V transfer rates. But this is not the case for the M-HC systems considered in this work. The de-excitation rates and are of the same order of magnitude as the V-V transfer rates and respectively. In order to determine separately all these rates, relaxation measurements have been performed by exciting either H to the level or to the v = 1 level, and measuring the relaxation rates versus the molar fraction of the gas excited by laser. The results are discussed and compared with the values of the rates calculated by using a Morse potential as the intermolecular potential, and according to a semi-classical method in which a vibration-rotation exchange is assumed
VIBRATIONAL COUPLINGS AND ENERGY FLOW IN COMPLEXES OF HC=CH, HC=CD, HC=CC=C, AND N=CH WITH
No full textAuthor Institution: Molecular Physics Division, National Institute of Standards and Technology; Molecular Physics Divisoin, National Institute of Standards and TechnologyInfrared spectra of the C-H stretching vibrations of the symmetric-top complexes, , have been recorded using a color-center-laser electric-resonance optothermal spectrometer. Efforts to observe the N-H stretches were unsuccessful. The hydrogen-bonded C-H stretching modes of HC=CH--NH3 are strongly coupled to the hydrogen bond as evidenced by their large monomer red-shifts of 75 and and broad predissociation linewidths of 2000 ad 650-800 MHz, respectively. The complexation-induced asymmetry in is not sufficient to allow us to observe the local mode associated with the outer C-H stretch. However, isotopic substitution in shows that this mode is red shifted by less than from the monomer vibration. The narrow predissociation linewidths of this mode (7-12 MHz) are consistent with this small red shift. The weaker coupling of the C-H stretches in HC=CC=CH is completely quenched upon complexation with . The outer C-H stretch is observed in the diacetylene (HC=CC=CH) complex, blue shifted by approximately from the infrared-active monomer C-H stretch at ; the bound CH stretch is red shifted about the same amount as in . These observations imply that the weak coupling of the local modes in diacetylene is significantly quenched upon complexation with . The predissociation linewidths are similar to those in , even though the outer C-H stretch is now five bonds away from the hydrogen bond. Surprisingly, these results suggest that the length of the triple-bond backbone in acetylene chains does not significantly impede the rate of vibrational energy flow. Future efforts will be made to extend these studies to the triacelyne complex,
Measurements of hc(P11) in ψ ′ Decays
No full textWe present measurements of the charmonium state hc(P11) made with 106×106 ψ ′ events collected by BESIII at BEPCII. Clear signals are observed for ψ ′→π0hc with and without the subsequent radiative decay hc→γηc. First measurements of the absolute branching ratios B(ψ ′→π0hc)=(8. 4±1.3±1.0)×10 -4 and B(hc→γηc)=(54. 3±6.7±5.2)% are presented. A statistics-limited determination of the previously unmeasured hc width leads to an upper limit Γ(hc)<1. 44MeV (90% confidence). Measurements of M(hc)=3525.40±0.13±0. 18MeV/c2 and B(ψ ′→π0hc) ×B(hc→γηc)=(4.58±0.40±0.50)×10 -4 are consistent with previous results. © 2010 The American Physical Society.published_or_final_versio
Hydraulic simulations to evaluate and predict design and operation of the Chashma Right Bank Canal
No full textIrrigation systems / Irrigation canals / Flow control / Velocity / Canal regulation techniques / Hydraulics / Simulation models / Design / Operations / Crop-based irrigation / Distributary canals / Water delivery / Policy / Protective irrigation / Water allocation / Water requirements / Sedimentation / Water distribution / Equity / Water conveyance / Pakistan / Chashma Right Bank Canal
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