1,237 research outputs found
Chemical specificity in short-chain fatty acids and their analogues in increasing osmotic fragility in rat erythrocytes in vitro.
We examined the role of the chemical specificity of short-chain fatty acids (SCFAs) and their derivatives in increasing osmotic fragility (OF) in rat red blood cells (RBCs). Except for formic acid, normal SCFAs with 2 to 8 carbons increased the OF in rat RBCs with increasing number of hydrocarbons in a dose-dependent manner. Replacement of the carboxylic group with sulfonic group inhibited, but did not abolish, the SCFA-mediated increase in OF. Introduction of another carboxylic group (dicarboxylic acids) completely abolished the SCFA-mediated increase in OF. Transformation of the hydrocarbon chains in SCFAs from straight to branched or cyclic chains affected the degree of the OF-increasing effect. Introduction of double- or triple-carbon bonds to the hydrocarbon chain in parent SCFAs did not affect the increase in OF. Both hydrophilic (carboxylic group) and hydrophobic elements (hydrocarbons) at opposite sides of a molecule were required to affect the RBC membrane, and the size and form of hydrophobic element were important factors in determining the SCFA-mediated increase in OF. The hydrocarbon chains probably enter the plasma membrane, with the hydrophilic carboxylic base remaining outside of the membrane, and interact with phospholipid in cell membrane and disturb the structure of lipid layer resulting in the increase in OF in the rat RBCs
Erratum: The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition (Proceedings of the National Academy of Sciences of the United States of America (2020) 117 (4180-4187) DOI: 10.1073/pnas.1913481117)
Correction for “The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition,” by Simone F. Glaser, Andreas W. Heumüller, Lukas Tombor, Patrick Hofmann, Marion Muhly-Reinholz, Ariane Fischer, Stefan Günther, Karoline E. Kokot, David Hassel, Sandeep Kumar, Hanjoong Jo, Reinier A. Boon, Wesley Abplanalp, David John, Jes-Niels Boeckel, and Stefanie Dimmeler, which was first published February 7, 2020; 10.1073/pnas.1913481117 (Proc. Natl. Acad. Sci. U.S.A. 117, 4180-4187). The authors note that Hitoshi Okada should be added to the author list between Karoline E. Kokot and David Hassel. Hitoshi Okada should be credited with providing mice. The corrected author line, affiliation line, and author contributions appear below. The online version has been corrected
Influence of perinatal factors on the appearance of pointing in very low-birthweight infants
ERRATA
Volume and issue: Vol.6, No.7 (2011)Page: pp.317-322Title: Contribution of Slip and Cleavage in Friction and Wear at (10-14) Surface of Magnesite (MgCO3) CrystalAuthor(s): Kaori Niki, Mai Kobayashi and Hitoshi ShindoVolume and issue: Vol.7, No.1 (2012)Page: pp.8-12Title: Frictional Asymmetry and Wear Pattern Formation by Slip and Cleavage Detected at Directional r {10-14} Face of Calcite (CaCO3)Author(s): Kaori Niki, Mai Kobayashi and Hitoshi Shind
Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970
Letter from John Lancaster, Chairman, American Institute of Floral Designers (A.I.F.D) addressed to the florists who are interested in attending the Yoke Kuromi Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars
Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970
Letter from John Lancaster, Unit President, American Institute of Floral Designers (A.I.F.D.), possibly addressed to the Southern California Teleflora Unit about the funeral for Yoke Kuromi.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars
Meeting minutes for Yoke Kuromi's memorial dinner, May 20, 1970
A copy of the meeting minutes for Yoke Kuromi's Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars
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