4,430 research outputs found
Osteoprotegerin and cardiovascular disease
No full textThe articles of this thesis are not available in Munin: 1. Vik A, Mathiesen EB, Noto AT, Sveinbjornsson B, Brox J and Hansen JB.: 'Serum
osteoprotegerin is inversely associated with carotid plaque echogenicity in humans', Atherosclerosis (2007) 191(1):128-134. Available at http://dx.doi.org/10.1016/j.atherosclerosis.2006.03.002 2. Vik A, Mathiesen EB, Brox J, Wilsgaard T, Njølstad I, Jørgensen L and Hansen JB.: 'Relation
between serum osteoprotegerin and carotid intima media thickness in a general population - The Tromsø Study', Journal of Thrombosis and Haemostasis (2010) 8: 2133-9. Available at http://dx.doi.org/10.1111/j.1538-7836.2010.03990.x 3. Vik A, Mathiesen EB, Johnsen SH, Brox J, Wilsgaard T, Njølstad I and Hansen JB.: 'Serum osteoprotegerin, sRANKL and carotid plaque formation and growth in a general population - The Tromso Study', Journal of Thrombosis and Haemostasis (2010) 8: 898-905. Available at http://dx.doi.org/10.1111/j.1538-7836.2010.03790.x 4. Vik A, Mathiesen EB, Brox J, Wilsgaard T, Njølstad I, Jørgensen L, Hansen JB.: 'Serum
osteoprotegerin is a predictor for cardiovascular disease and mortality in a general population – The Tromsø Study', Journal of Thrombosis and Haemostasis (2011) 9: 638–644. Available at http://dx.doi.org/10.1111/j.1538-7836.2011.04222.x</a
On unitary convex decompositions of vectors in a -algebra
No full textsummary:By exploiting his recent results, the author further investigates the extent to which variation in the coefficients of a unitary convex decomposition of a vector in a unital -algebra permits the vector decomposable as convex combination of fewer unitaries; certain -algebra results due to M. Rørdam have been extended to the general setting of -algebras
Dynamic Regulation of Genes Involved in Mitochondrial DNA Replication and Transcription during Mouse Brown Fat Cell Differentiation and Recruitment
No full textBrown adipocytes are specialised in dissipating energy through adaptive thermogenesis, whereas white adipocytes are specialised in energy storage. These essentially opposite functions are possible for two reasons relating to mitochondria, namely expression of uncoupling protein 1 (UCP1) and a remarkably higher mitochondrial abundance in brown adipocytes. as well as in white and brown fat, brown adipose tissue fractions and in selected adipose tissues during cold exposure. We find a massive induction of the majority of such genes during brown adipocyte differentiation and recruitment, e.g. of the mitochondrial transcription factors A (Tfam) and B2 (Tfb2m), whereas only a subset of the same genes were induced during white adipose conversion. In addition, PR domain containing 16 (PRDM16) was found to be expressed at substantially higher levels in brown compared to white pre-adipocytes and adipocytes. We demonstrate that forced expression of Tfam but not Tfb2m in brown adipocyte precursor cells promotes mitochondrial DNA replication, and that silencing of PRDM16 expression during brown fat cell differentiation blunts mitochondrial biogenesis and expression of brown fat cell markers. model systems of white and brown fat cell differentiation, we report a detailed characterisation of gene expression linked to mitochondrial biogenesis and function. We find significant differences in differentiating white and brown adipocytes, which might explain the notable increase in mitochondrial content observed during brown adipose conversion. In addition, our data support a key role of PRDM16 in triggering brown adipocyte differentiation, including mitochondrial biogenesis and expression of UCP1
Erratum: Half-supersymmetric solutions in five-dimensional supergravity (Journal of High Energy Physics (2007) 12 (025))
No full text[No abstract available]Gutowski JB, 2007, J HIGH ENERGY PHYS11
Deformation density of A diazirene ring in the X-ray structure of 3-[(Para-nitrophenoxy)methyl]-3-chorodiazirine
No full textPT: J; CR: BAERT F, 1982, ACTA CRYSTALLOGR A, V38, P143 BATTAGLIA R, 1980, Z NATURFORSCH B, V35, P719 CARRUTHERS JR, 1989, CRYSTALS DUNITZ JD, 1973, ACTA CRYSTALLOGR B, V29, P589 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 HANSEN NK, 1978, ACTA CRYSTALLOGR A, V34, P909 HEINE HW, 1983, SMALL RING HETEROCYC, V2, P547 LINDEN A, 1988, J ORG CHEM, V53, P1085 LIU MTH, 1987, CHEM DIAZIRINES MOFFAT JB, 1978, CHEM DIAZONIUM DIA 1 PIERCE L, 1962, J AM CHEM SOC, V84, P2651 REGITZ M, 1989, HOUBENWEYL E B, V19 SCHMITZ E, 1979, ADV HETEROCYCL CHEM, V24, P63 SEILER P, 1988, HELV CHIM ACTA, V71, P2100; NR: 14; TC: 10; J9: J AMER CHEM SOC; PG: 2; GA: HF639Source type: Electronic(1
Surjective isometries between unitary sets of unital JB∗-algebras
No full textWe would like to thank Prof. Lajos Molnár for encouraging us to explore this problem.
We are also indebted to the anonymous reviewer for several useful comments.
First and fifth authors partially supported by the Spanish Ministry of Science, Innovation and Universities (MICINN) and European Regional Development Fund project
no. PGC2018-093332-B-I00, Programa Operativo FEDER 2014-2020 and Consejería de
Economía y Conocimiento de la Junta de Andalucía grant numbers A-FQM-242-UGR18
and FQM375. First author partially supported by EPSRC (UK) project “Jordan Algebras, Finsler Geometry and Dynamics” ref. no. EP/R044228/1. Second author partially
supported by JSPS KAKENHI Grant Number JP 21J21512. Fourth author partially
supported by JSPS KAKENHI (Japan) Grant Number JP 20K03650.
* Funding for open access charge: Universidad de Granada / CBUAThis paper is, in a first stage, devoted to establishing a topological–algebraic characterization of the principal component, U0(M), of the set of unitary elements, U(M), in a unital JB⁎-algebra M. We arrive to the conclusion that, as in the case of unital C⁎-algebras, U0(M)=M1−1∩U(M)={Ue⋯Ue(1):n∈N,hj∈Msa∀1≤j≤n}={u∈U(M): there exists w∈U0(M) with ‖u−w‖<2} is analytically arcwise connected. Actually, U0(M) is the smallest quadratic subset of U(M) containing the set eiM. Our second goal is to provide a complete description of the surjective isometries between the principal components of two unital JB⁎-algebras M and N. Contrary to the case of unital C⁎-algebras, we shall deduce the existence of connected components in U(M) which are not isometric as metric spaces. We shall also establish necessary and sufficient conditions to guarantee that a surjective isometry Δ:U(M)→U(N) admits an extension to a surjective linear isometry between M and N, a conclusion which is not always true. Among the consequences it is proved that M and N are Jordan ⁎-isomorphic if, and only if, their principal components are isometric as metric spaces if, and only if, there exists a surjective isometry Δ:U(M)→U(N) mapping the unit of M to an element in U0(N). These results provide an extension to the setting of unital JB⁎-algebras of the results obtained by O. Hatori for unital C⁎-algebras.CBUAConsejería de Economía y Conocimiento de la Junta de Andalucía
A-FQM-242-UGR18, FQM375Ministerio de Ciencia, Innovación y UniversidadesEngineering and Physical Sciences Research Council
EP/R044228/1Universidad de GranadaMinisterio de Ciencia e InnovaciónJapan Society for the Promotion of Science JP 20K03650, JP 21J21512European Regional Development Fund
PGC2018-093332-B-I0
Flexible time–space network formulation and hybrid metaheuristic for conflict-free and energy-efficient path planning of automated guided vehicles
No full textOperations of Automated Guided Vehicles (AGVs) are desired to be more energy-efficient while maintaining high transport productivity, motivated by the green production requirements. This paper investigates a new energy-efficient planning problem for determining conflict-free paths of the AGVs in its transport roadmap. In this problem, the vehicle path and transport time in the roadmap are jointly optimized, based on a flexible time–space network (FTSN). We provide the mathematical problem formulation of the energy-efficient path planning problem. The resulting optimization problem is proved to be a non-convex mixed-integer nonlinear programming which is computationally intractable. We further propose a hybrid metaheuristic that integrates the genetic algorithm and estimation of the distribution algorithm to improve its computational efficiency. Numerical results show the effectiveness of the developed algorithm based on the FTSN framework, compared to the existing metaheuristics, the conventional path planning method, and a commercial solver. The proposed method has a wide application in improving energy use of material handling, providing a guiding significance on promoting cleaner production of flexible manufacturing systems.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport Engineering and Logistic
Proteomic analysis of rainbow trout (Oncorhynchus mykiss, Walbaum) serum after administration of probiotics in diets
No full textThe response of rainbowtrout (Oncorhynchusmykiss, Walbaum) towards probiotics present in the feed was investigated by examining the proteome of serum as a measure of the acute phase response (APR). Proteomicanalysis by two-dimensional electrophoresis (2D) concurrently with mass spectrometry was used to detect APR related proteins in rainbowtroutserum following feeding with probioticsAeromonas sobria GC2 and Bacillus sp. JB-1. Three candidate proteins increased following use of GC2, and were putatively identified as NADH dehydrogenase, dystrophin and mKIAA0350. Conversely, one of the proteins, which were induced following use of JB-1 was identified as transferrin
Decoupling of genome size and sequence divergence in a symbiotic bacterium
No full textAuthor Posting. © American Society for Microbiology, 2000. This article is posted here by permission of American Society for Microbiology for personal use, not for redistribution. The definitive version was published in Journal of Bacteriology 182 (2000): 3867-3869, doi:10.1128/JB.182.13.3867-3869.2000.In contrast to genome size variation in most bacterial taxa, the small genome size of Buchnera sp. was shown to be highly conserved across genetically diverse isolates (630 to 643 kb). This exceptional size conservation may reflect the inability of this obligate mutualist to acquire foreign DNA and reduced selection for genetic novelty within a static intracellular environment.Financial support was provided by a National Institute of Health
postdoctoral training grant to J.J.W. (Center for Insect Science, University
of Arizona) and a National Science Foundation grant (DEB-
9815413) to N.A.M
Vertical transmission of biosynthetic plasmids in aphid endosymbionts (Buchnera)
No full textAuthor Posting. © American Society for Microbiology, 2001. This article is posted here by permission of American Society for Microbiology for personal use, not for redistribution. The definitive version was published in Journal of Bacteriology 183 (2001): 785-790, doi:10.1128/JB.183.2.785-790.2001.This study tested for horizontal transfer of plasmids among Buchnera aphidicola strains associated with
ecologically and phylogenetically related aphid hosts (Uroleucon species). Phylogenetic congruence of Buchnera
plasmid (trpEG and leuABC) and chromosomal (dnaN and trpB) genes supports strictly vertical long-term transmission
of plasmids, which persist due to their contributions to host nutrition rather than capacity for infectious
transfer. Synonymous divergences indicate elevated mutation on plasmids relative to chromosomal genes.This work was supported by a National Institutes of Health postdoctoral
training grant in Molecular Insect Science (Center for Insect
Science, University of Arizona) to J.J.W. and a National Science Foundation
grant (DEB-9815413) to N.A.M
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