18 research outputs found
An a-Si TFT with a new light-shield structure and its application to active-matrix liquid crystal displays
No full text
Multi-Omics Analysis of Anti-Inflammatory Action of Alkaline Extract of the Leaves of Sasa sp.
No full textEfficient utilization of alkaline extracts of several plants for the treatment of oral diseases has been reported. To investigate the mechanism of anti-inflammatory activity of alkaline extract of the leaves of Sasa sp. (SE), multi-omics analysis using metabolomics and DNA array was performed. Human gingival fibroblasts (HGFs) were treated for IL-1β to induce inflammation (detected by PGE2 production in culture medium) in the presence or absence of SE. Both IL-1β and SE showed slight hormetic growth stimulation against HGF. SE inhibited PGE2 production dose- and time-dependently. Its inhibitory action was more pronounced by first treating the cells with SE, rather than with IL-1β. At 3 h after IL-1β treatment, 18 amino acids (except cysteine and glutamic acid), total glutathione (GSH, GSSG, Cys-GSH disulfide), Met-sulfoxide, 5-oxoproline, and SAM declined, whereas DNA expressions of AKT, CASP3, and CXCL3 were elevated. These changes were reversed by simultaneous treatment with SE. The present study suggests that the anti-inflammatory action of SE is mediated via various metabolic pathways for cell survival, apoptosis, and leukocyte recruitment
Versican is induced in infiltrating monocytes in myocardial infarction
No full textVersican, a large chondroitin sulfate proteoglycan, plays a role in conditions such as wound healing and tissue remodelling. To test the hypothesis that versican expression is transiently upregulated and plays a role in the infarcted heart, we examined its expression in a rat model of myocardial infarction. Northern blot analysis demonstrated increased expression of versican mRNA. Quantitative real-time RT-PCR analysis revealed that versican mRNA began to increase as early as 6 h and reached its maximal level 2 days after coronary artery ligation. Versican mRNA then gradually decreased, while the mRNA of decorin, another small proteoglycan, increased thereafter. Versican mRNA was localized in monocytes, as indicated by CD68-positive staining, around the infarct tissue. The induction of versican mRNA was accelerated by ischemia/reperfusion (I/R), which was characterized by massive cell infiltration and enhanced inflammatory response. To examine the alteration of versican expression in monocytes/macrophages, we isolated human peripheral blood mononuclear cells and stimulated them with granulocyte/macrophage colony-stimulating factor (GM-CSF). Stimulation of mononuclear cells with GM-CSF increased the expression of versican mRNA as well as cytokine induction. The production of versican by monocytes in the infarct area represents a novel finding of the expression of an extracellular matrix gene by monocytes in the infarcted heart. We suggest that upregulation of versican in the infarcted myocardium may have a role in the inflammatory reaction, which mediates subsequent chemotaxis in the infarcted heart
A systematic measurement of energy resolution and e/π ratio of a lead/plastic-scintillator sampling calorimeter
No full textStudies into the Failure Prediction of Brittle Materials
No full textThis thesis is divided into six chapters. The first chapter
provides a brief introduction concerning the behaviour of brittle
materials. It also contains the justification for the undertaking of
the study as well as a brief description of the method of approach
adopted, and thesis layout. Chapter two provides a critical review of
the current literature available at present in the failure prediction
brittle materials. Both theoretical and experimental studies are
discussed and the relevance to the present work is justified. Chapter three deals with the numerical analyses adopted within
the thesis. Five different failure criteria were utilized in the
initial analysis of the results presented. Among them, the empirical
model using the Principle of Independent Action satisfactorily
represents the biaxial fracture behaviour of brittle materials in
both tension-tension and tension-compression quadrants. Its validity
has never been tested before. Various statistical fracture models
were used to analyze the failure of brittle materials under multiaxial
states of stress, the experimental failure data for simple tension
being a starting point for their calculation. It was shown that the
Energy Density theory led to a better agreement with the experiments
than any other well-known fracture criterion. The study investigates
methods of evaluating the Weibull parameters which were crucial in the
failure prediction of brittle materials. Monte Carlo simulation
techniques are also presented as a method of evaluating the data
ranking for the failure probability of brittle materials. Chapter four is devoted to the description of experimental
techniques adopted in the study, using specially designed rigs. Six
different tests were conducted to evaluate the performance of brittle
materials in static loading and also to enable comparisons with the
theoretical predictions. Attention was given to specimen casting,
loading frames, alignment, measurement techniques and other relevant
parameters. The use of the linear elastic fracture mechanics method
to predict the behaviour of cracks in bodies, which are subjected to
steady stresses, is discussed. The compliance function for the
three-point notch bend specimen is presented in addition to the
determination of the fracture toughness of Herculite LX plaster. The work was also supplemented by the use of scanning electron microscopy
(SEM) to failure analysis of plaster material. This is an extremely
important tool in the study of brittle materials since the dimensions
of small defects and fracture features on individual grains are often
pertinent information to the failure analysis.
Chapter five details the analysis of the theoretical results as
well as the experimental findings. Based upon the previously
mentioned approaches, a comparison was made between theoretically
predicted and experimentally observed data. The comparison indicates
that discrepancies exist between the observed and predicted results,
the reasons for the discrepancies have been justified in this work.
Chapter six provides a brief summary of conclusions derived from
the complete study, together with recommendations for future work
0005
No full textDAILY PALO ALTO TIMES. MONDAY. JL'KF. it, 1910
Common Cruelties of
_Jvery-dayOcw^
STRONG PULSE BEATS.
Csstt I* WMah They Ara Psrssstlbss
M tM f y*.
* -The Pearl Hast*'.' Super*'it. en.
The pearl btnt*rr* of Morp*o end I
«dj*c*ai Islands Mr* * pst-ullar 1
perslllloo. When Ibey open a-tt-ila lu
IKCOKnMTK*! IKm
iv 11:1 ti mi s: Acronnrn
nowBSTir akimaIaM.
-11 I* aot each en aa.-ommoo (blag.** ****** *' ******* **** **** ***** *****
-Hd a physician. ■-to Bad . p-rr*oo flo*J' ******* " ** *"* " I*****0*
m.,,.. ,m*m. t .... ,n j, nl.tnl .,■■*. \ ***** ** ***° * ******* ***** * *****
*-.*_. -. Vim* ~"* "■ ** **"." T^ ' «wked sviih a dead wee's **xmt* Tl -
PHUPlaK and r** I aata-— tt-*- era but •*■'.,. „. lb_ „-_, .-, kmmmu „ -^__-
ontsld* *f Ik-profta-loa wM rsallne. fmtW. „ -n_f-gta, ^rt..- sad (M
tka fact, la meet persons tto beat ef Umivs Bsei»**asd gnnty bsllrv** thai
tM pates ****** b* p*rr*4ved. bal ite1 the) will rsprodore their klad. Por
mar* fact ttot IM Meting to paacapO* j every pearl pat tolo (M.rtol two
l* j grain* of rk* at* thrown la for iM
a, ) |-eerie lo "feed t11-.11 " Some white*
la Borneo, believe as Irmly In
Th* humane bar**** of Pnlo Altu
ka* laat. ieoaed a unique drt-ulnr,
radtlng *ora* of lb*, common ernst-
tlaa to wblefc. domestic animals are
aobmltted. . Tk« egort to made by
lb* hnraaa ta th* hop* ef laaatrteg
fnara of bor*M. do**. *u. to a*>
aord tk*m hiadar traglta-Mt nnd
-bnttor car*. Tk* Hrrular raeda ss
follow*:
"Do w* grown falka Mt an sum.
pis nf kindest* or craslty* Aald*
from tba *t*mp!o w* ant Meh eih ■
*r, let'* (hlnk of ten* of th* Incon-
etotnairle* of ordinary folk, and their
•fort oa children '
"Summer vacation to coming, and with **ch Mat of tbeaadnn.
plaa for an ontlng. Ann we toare •***! ** ***** *** I**-** ***** *•_»_
tk* Mt w* have fad nnd wnterwd »!^._^_ __"■"**"_ *****
.-.A ,—t,m_4 tat —m a ..«,* Wx* tt *** ****** tniWJgh IO ke«p IM IWCOIW
and p*tt*d td ha a etray? Mot if 3^ ._. ______ ____* n „ ^ m cja-i.
wa know whnt. lira* Neb rata lead. -j-. , ,_-_, „ ___ mmti »,-, ._
and whnt death*, mod how ron- «,*._*- H wna oagi-ant and (Mt itor*
fused moat fb* etklldren of (he tpaa 00 intotnk* In my co*ntlag wltb
brmM ba whan th*f see their par* tM Mbed •**,"
Ms com oat mean thai tM pnl
ether (Maoortnal I Mr* com* *•'■*
a number of nee* wbera the tbrat-i.ii.,
af tb* wrist could be plainly
pet tka paraoea rarely gar* -rrldsroce
af abaormallty la tamperatarn- Tb*j
wer* raraly feverish and war* la go.-d
■kynlcal condition gsasrally Pal*-**.
ef thto klad. from thto vtow. wbVb 1*
ba**d apoa acraal ebeern
tneee, do aet ladteau aaylhtng mom
tktS aa aboermal pby*ac*l -fowditl-o*
to IM fernatttoa nf tto wmi vats*
1 tor* mat with aa****** which was
ponatMy a Mid* *strat*-*dlaary in thai
tt wm plainer and much ■tot* dtnln- •
ttot aay I bad orot eem nefora. if
troold almc-st to heard. Tto an**)
woald riss to * point almost sa lar,-.
m the ball ef the lltfle BngM nf •
child aad Would -toon from tb»
while ef tM ***a te a bteod pan. I.
•uita kind tn th* j*t erery °*y for
a rear and tbea abandon It.
"Do aw chain a dog? How can
a child grow np thougbtfnl of (b*
thrhta of ntk*r pawpla If he la tntght
It In- right to ks*p an actlr* dog
atraggllag pt tha end of a chain
THE ARTIST WON.
HI* Nerve and HI* Dm.*.. , Csmbtte_
{-•rsiltloa m th" nallrr* do, sad al
iiii-at stery bnt along (to co*a( Ms He
dead flag***** trottl*. wltb ITom ulne
to Bf(y eeed ptmrto and Iwlr* IMI
nsuber of rice grain* rarafnliy *nd
evroiy atosred away ameag them
That me malt* fottow do** aot dim
(M *aperstiuoa .
Tke Westdsef.l Teed Setse.
-AB eejly svrKsrs stlribwie *-o*d*rf*l
gMllttoe to (osd* and frog* aad the
rartoM parts of iMtr t-odle*. Pllay
MUeved, tor laetaoc*, (Ml If a lend
ww bum-flit Into IM rnMsl of a motor other Inrg* and Barely c-oocoarn* uf
people "alienee would In.lanilj j.rr
vajl." A small boo* tamed In tM rljiit
lids of-toeda "ef IM proper eg** wa*
alao believed te bat*, power* o*ra- ikt
By 1 brew Ing ibis
lain a eetmH of hotting water."
eava PTtay. 'it wltl imt**--iUat*ly ewei
it. tke water rafMlag ie boll again on
HI ,(M Ma* ha* bswa rataorad. T«
Snd thto Mas. expo** tbe**-Se*d toed
en nn anl bill. Wbn lbs ant* Mve
seteu ber all away etraat lb* bun***.
tab* each b»M t*t*pent**r and. drop li
late boiling water Thu* may' tbe
j wondrous toad Isoo* b* dlaraverad."
Alt Aflsient A*tr**s*ws*e.
sboui f>a> It c. AMUgone tsf lo
The editor bad gt*** tto ante* aa ate area born. When be "grew np In
etretor ta Ulaetrat* tto *tory aad bed thtia" M waa iM'Sref to learh IM
drawn a reagb diagram of IM bind ••!. cwnra* and rapm ot both solar and
De w* tsar* lbe eat. or th* dog, er a_uuh w «„(_. It „»„ Mow * Inner atllt*** and t* give hto foUowet*.
tk* thick*** without sratorT Some arm vaulting la a hl0 toap etet a
of na do. damp of bnsbsa. The arttot rand (be
'"DO we drive wttb an oserhead m**oacrlp(. mad* (M ptetar* and sent
check and a whip? Only lh* yoaog- " >■ " *** ****** ****• 9* ***** ***
B chlldreu ar. -gaorant ahonl ,h. yS-^JtS V-h\-*S-a* k
chork. and *van tb* youngest ran mgM „,, ^ ^^ _f -^ _,,„_.J
learn cruelly from th* whip- -»** m -^og __t ,bt -jrawlag aad tbtm I ***** ** ooa*clence 1* apt to
"Do we om motiMtraia that catch hi dtagntt ratnrn*d'lt to (to antei.'.atlllM and smaller
■Im wlthoat hurting (nana, nnd with a letter autlng tMt tto Sgur*'
mtot wtoraby (bey roaM dlatlnguUb
planels from !i--.l stars He —
pnatobed for devlarlng thai tto
waa not a gtaB.
At time rolls oti. th* atlll email
th«a do ws forget to look In the
trap f*r a w**k? PoMlbly *oaa* of
e* bar* dtoreverad th* neg"sct*d
trap when Ihe rblldrea wer* looking on. and bar* hsnrtj thtrlr vzcla-
nutloBt aboal starving ihe animal
(o death
M redrawn baraaM tk* Mttcy | tn .* ______ . r.
plainly state* tMt (M beck was • 30latn6rD jTaCIllC
yearling. t*oo*eq**wtly to wonld Mttj
and net IM bind
bad on>y ****** bora*
of aattert yoe f***r drpict****
Tb* artlsi
wyad Hs stood pat for antler*. Wllh
courage born of faraovatito-ceavktlt--.
Time Table.
(Is effect Jan* is. mm.)
THE MASTERPIECE
PREMIUM OFFER
Unsurpassed in sny Newspaper Office in America
How about Being tllcbj Itrpaporf ** -wtBrasd Ut* drawing unaltered 1..
Nvm grown folk* tall It unpl*
to bars around, and It ta difficult lo
SWt a grown person to watch one fly
tbe editor and wired Mm ***>m|*o*i .
tlon demands a otter*., Change msn*. j •**• •*
acrlptto-ihrtrs-jear-old buck'" ' No. •*■ (Valeacl*).
Tbs sdlior ssaa struck so dumb by , No. &7 (** Kutidat
. • * ~* ma**m. *• an am v*. m «v .mu.Lt i*j
nntll It diss. tea.*, h* know* It Is _, uMntfaeutlon of nwe that *M
Mt a quick daatb. Bnt to th* actaaity teak dm* to atndy tto draw
Ins- Ba tot kla Imagtoaitotf ptetar*
tto spite bora lamaad of tte tnajtotk
aatteesd Maaty and aswafcly derided
thai IM arttot knew n tklag ar two.
M A* edilortel MM pencU wm
brought Into rsqulaUton. Um back gain
ed two year* In a Iota &amt**f of rain
nt**, and tM pe-rtodteal loat nothing
by (hs rtong*._:*.*W Torb Pre**
child th* ty to 044 mora lira Mint! to leer* aboat. nnd Sn we want
blm In toarn th* 1 aet on of lingering
death, evee of the fly?
^What*. klad of Ids** nail children hair who ato tbetr parbntt
klad lo evert' Hry a-jima!, but (he
mother wsarttg wing* and lalla ob
- htr hat and fnra dangling round
• h*r enrh*
"Doe* ih**a--,an af Ibe houa* use
bis far* varatlona by going oJf with
* gsn, 10 kilt MmelblngT If he doM
Ihla. (he effet-t la .to blunt the*a*n-
MMIItle* of Jtfa chlldrea. and confuse tbeut again as te whether animals hare rights It Is a ahoTt step
tn whether. other people bare
right*
"VV*. want our chlldrao to M
■ kind when iher are children, and
Und when la4jjr take tbalr placee a*
workers and parents 8ap|*oee ws
Ml a tetter example every day la
kindness lo animals
"Whan drlvlar for ptstaanr*. of
yea will Mop for a Thw Maau itntok
aaw'and iheklt will glv* th* horaM —----—-—___
a murh-needed rsat whll* yoa •*• . *by Ttaehte*. Wtm-t. Os VsUtad.
lov lb* acenerV . Tnrtlab women do-nol we*r relte
***tm -mi at* ii.. /t,t.-« .. t.s.1. beraiiee et their railgtoo. aa many au|i
. ^m^L n- 1. ai? ****** ** * ***** *** ***>**)**' ** **
or urge (he noraea «"•>•**
1:11 r«
III run
• :11 nm.
lltS a.m
No » IL.0 cutof.es It ) Till a «
Nn. 41 (ng.tnnl.-. til mm
M4.. 4* , 7:47 an.
M* 4S lw Use 1 *:•* *m
Mn. 4T I II am
-fffb **. (st'Cjna M.S-1 -1S:14 a_a
(Regular atop.)
QterM instruettoaa. '■
Mr. DebM wm atlll oal tt 1 a. ta
UMbte to trait calmly an* loag*r.
Mrs- D*bM bexan pacing tte btU. gh« No II.
bad aoae beck aad fenk about thirty-.
••raa tlm** wttea ate heard a tbuupl
at tM back door.
Ste walked back and paerad iteoagb.
the glaaa ll tree Mr. D*J. be. all right: e**\ **
Ue eeemsd 10 have fatten la tte mnd
two of tbra* tl dm*.
lbs Im him Id and ataadted Um up
stairs
"Why did yon cam* to tto. bark
doorr tto sakeO.
lis colteclsd bto fugitive wile tefor*
No |»t.
Mn. If
Nn 4* ,',..
[No H IS Crut ***,).
II (*a.l
•ol* .
"Ther* to s etgn tn front wbVb My*
(Mt all pacbagM most te dellvs-sj-ed at
ahL-SL Lento Post InC
whsn th.ey are. .^ clMom .-f^,- tbfJ *-*__,,, miu
* ***** In Tartar*, tefor*. lb* (lake ot
"Do not ride behind d docked or tfotemtiit-d. ll wm th* Mbli of (he
highly-cheeked bora*. If you put att to atMl sneh, women for wte** sa
yonr ham* up In a Strang* tub** at|racisd Item. Tbla tod jo ee aiu>b
b* euro to bm that b* taaa gnod food. T*Ato« ***' ***** *** ******* *********
bedding tad
comlortahle atoll wide enough for
htm to It* down In.
's-ooh "»ltM your own "bora**. R*.
_ member you are raeponalbl* for
their car* and should protect them "
after Cartel tM Turks ram* logHMt
tad derlttea (Mt MMWhv-rtb Ite ww
-see ahouM go relied and should ■*...
nwat uses, bet dw*a' to tstv-rrtajs, aa
aaaa ps ia*y arrlrvd at *<•*.tssj-to
whkrh sas et about eieirtt years nt
ag*e-Urs Ketinrth Srown In Uelrr*
polliao MtgarJM.
' CM* Fell. r».
fuin.t our mlohtrr. o*t*r gt-ta
rrntarksd tit** young Huts-
Th* apMkM ot _ tb*. ntUonal
bouto It mora ottag lu th* nubile
■O eye. thai. lh* vtrs-prr.ldrnt. , hut
— bnurefortl. he la not likely to b* so Mad wis. had Jmft refused his «If- a
Often Man In an automobile - no*.- aew drat* In bto.**«dMver to change
ten Ttnnaertsq tk* sui.js.-i -l think he'd mage a
'ant**
e wife war**.-.
ato a vary good
P/TENTS
He Oet HI*
A eyuk-al old .bacben-r wte Irmly
toltovee that all women Mve eeam-
Iklar to My on ail mb)et-to raceaiiy
aakad e female mead:
"Well, madam, what do MS MM w*
this question ot female tufrrager
To which tte lady
"Sir, I bold my
Till ttase te Itr
- ****a*t kr
Mn- It..
No II..
;i
Mn. 17 1 Santa Trui. .
So ll (Sunday onlri
» 14 a.a
11:14 am
ll:»l p»
.11111 P.m.
1:17 p.m
l.tl pa
. I ♦• pm.
4 17 pm
toll pa
4 14 pm
•lit* p.m.
*: !• P.m.
. 1:47 P.IB.
II: II pjg
'Nn. Jt (dailji I:4t pa
Mtw-t|.. '...'. lilt an.
(Saau Ctm vln P*j*r* •
*te. II (Saaday oaly) .. Ill ia.
Ma SS (m. tjnuda-» ... Ill at*.
Ma. 14 tSenur-ruai 1:11 a-i
***• 'Regular siap.l -
No. 14... -.. 1:11 am
Mn. II 11:41 am
Mn, 41 .11:41 pm
No. .0 (Sal. only) -' "" pm
No || 7 l:«l pm
(On flag foe S, Cm* A Pern. Drove.I
Nn. 41 till pm
No. ■*.« l_r n Sun > I "'■ ps
Nn. tn. 1. 1:11 pa
No 44.' I. II *m
No— il. r. « Sun)... I:ll p->.\
Nn. 41 (m. Ban.).. :■ 14 ~
No. 41 lag.tnn.) *■*•
Nn. It in.San.).- 11*
No. St........ I141
No .1 (es ..1*L0 eel) 1 ■ Oft
No It....- 7,1> p.m;
>*o. Jit''(tan* ■Angeles l ■ *'■*** p.m.
No. i* flBan loa*) lY.*t p.m.
**
-IrmT year uwteh
***********-
: act au rs. mt i
.*' Only a few sets let! and this offer will lie withdrawn. P*»sn-
i-ie have never before been given the opportunity lo obtain suom
sn unusual pri-tuimii. nnd no oiher paper iu California offers it.
33 PIECE BREAKFAST SET
*3lb nSnQUeb JSlue Millow WLare
With ycitily subscriptions to. tht
Daily Palo AJto Times
j Vt'edajewood Potteriss.
014 Httic Willow. Ware lias become So pop.iUr the. world
over that it has been necessary for the Wedpr*\*s*v>d Corapaay,
l.tmited, at Tun.-ia)!.'KncliiBd, t*~> erect two. new firing kites to
supply (he great demand on'their putteries for this ancient and
iuierr. ttug design:
Price in Ssn FrsncUco.
A Palo Alio woman found upon inquiry at a large crockery1
house in San Francisco, lhat the present market, price for this
grade of Jllue Willow* Ware averages 12 1-2 cent, for'each piece.
A .l.Vpiece set at tilts rate wotild cost 4.00 for the dishes alone without the i.mmense -pkjasurc aod satisfaction of reading a local family journal every evening of the
year, with all the neus of this gTOwing and thriving comM'ui*itpy.
THE TE.RiMS
■ Y«u pay 1.00 to cover transpoVtation charges n the Willow Sacs
from the potteries to us. total to' new subscribers. 1.00. to
share with us, in a small nay, the actual cost ot procuring this
remarkable premium.
- These breakfast dishes may be inspected a( the Times oSce
and need only to be seen to bc'adimired.
Call at the Times Office any day betu-een eight and five-
thirty and leave your" order for the Times to begin at once. " .
THE TIMES BUILDING
Corner Hamilton Avenue and Ramona Street
First measurement of the transverse spin asymmetries of the deuteron in semi-inclusive deep inelastic scattering
No full textAlexakhin VY, Alexandrov Y, Alexeev GD, et al. First measurement of the transverse spin asymmetries of the deuteron in semi-inclusive deep inelastic scattering. Phys.Rev.Lett. 2005;94(20): 202002.First measurements of the Collins and Sivers asymmetries of charged hadrons produced in deep-inelastic scattering of muons on a transversely polarized (LiD)-Li-6 target are presented. The data were taken in 2002 with the COMPASS spectrometer using the muon beam of the CERN SPS at 160 GeV/c. The Collins asymmetry turns out to be compatible with zero, as does the measured Sivers asymmetry within the present statistical errors
