35,655 research outputs found
Legittimo impedimento: un'interpretazione della L. n. 51/2010 conforme a costituzione è possibile e non è inutile
No full textRiforma della Costituzione e atteggiamenti del giurista. Considerazioni di metodo e una postilla di merito a prima lettura del progetto governativo di intervento sulla forma di governo nella XIX legislatura
No full textCorrigendum to: Geology of the Victoria quadrangle (H02), Mercury (Journal of Maps, (2016), 10.1080/17445647.2016.1193777)
No full textWhen the above article was first published online, the third author was incorrectly listed as F. Ferranti. This has now been corrected
Randomized Trial of Observation and Execution of Upper Extremity Actions Versus Action Alone in Children With Unilateral Cerebral Palsy.
No full textBACKGROUND: The properties of the mirror neuron system suggest a new type of upper limb (UL) rehabilitation in children with unilateral cerebral palsy (UCP), based on observation of action therapy followed by execution of a variety of observed movements (AOT).
OBJECTIVE: We tested the effects of AOT in the Upper Limb Children Action Observation Training (UP-CAT) trial.
METHODS: In a randomized, evaluator-blinded, block-designed trial, 24 UCP children with mild to moderate hand impairment were assigned to 2 groups. The experimental group observed, 1 hour per day for 3 consecutive weeks, video sequences of unimanual or bimanual goal-directed actions and subsequently executed observed actions with the hemiparetic UL or both ULs. The control group performed the same actions in the same order as the experimental sample, but had watched computer games. The Assisting Hand Assessment (AHA) scale was the primary outcome measure; the Melbourne assessment and ABILHAND-Kids were secondary ones. Outcomes were assessed at 1 week (T1), 8 weeks (T2), and 24 weeks (T3) after the end of the training.
RESULTS: The experimental group improved more (P = .008) in score changes for the AHA at the primary endpoints T1 (P = .008), T2 (P = .019), and T3 (P = .049). No between-group significant changes were found for ABILHAND-Kids or Melbourne assessment.
CONCLUSIONS: UP-CAT improved daily UL activities in UCP children, suggesting a new rehabilitation approach based on a neurophysiological model of motor learning
The impact of HPV female immunization in Italy: model based predictions.
No full textThe Human Papillomavirus (HPV) is a sexually transmitted virus that causes cervical cancer. Since 2008 a vaccination program targeting 12-year-old girls has been initiated in Italy, backing up the cervical screening program already active since 1996. We propose a mathematical model of HPV transmission dynamics with the aim of evaluating the impact of these prevention strategies. The model considers heterosexual transmission of HPV types 16 and 18, structured by sex, age and sexual activity level, where transition to sexual activity is explicitly modeled from recent survey data. The epidemiological structure is a hybrid SIS/SIR, where a fraction of individuals recovering from infection develops permanent immunity against reinfection. Infections may progress to cervical lesions and cancer and heal spontaneously or upon treatment. Women undergoing hysterectomy (either after treatment of HPV lesions or by other causes) also transmit HPV infection. The model fits well both the age-specific prevalence of HPV infections and the incidence of cervical cancers in Italy, and accurately reproduces the decreasing trend in cancer incidence due to the introduction of the screening program. The model predicts that if the screening coverage is maintained at current levels, even in the absence of vaccination, such trend will continue in the next few decades, eventually plateauing at 25% below the current level. The additional initiation of routine vaccination targeting 12-year-old girls will further reduce cervical cancer incidence by two thirds at equilibrium, under realistic assumptions of 70% coverage and a duration of protective immunity of 50 years. If catch-up immunization of 25-year-old women at first cervical screening is also introduced, about 3,000 cervical cancer cases overall can be averted, corresponding to 9.6% of all cases expected in the scenario without catch-up. We conclude that HPV vaccination in addition to cervical screening will significantly reduce the burden of cervical cancer in Italy
Dalle novelle al teatro: il laboratorio dello scrittore
No full textIl saggio è focalizzato sullo studio del procedimento creativo di Ugo Betti, il quale sottopone a una meticolosa revisione i suoi testi, sia in fase compositiva che in fase di edizione in volume e/o su periodico. Dall'analisi di manoscritti e dattiloscritti inediti, condotta dalla sottoscritta, si ravvisano la continuità d'intenti, temi e motivi fra i diversi generi letterari e la molteplicità di rimandi intertestuali, che attestano la complessità e il valore di tutta l'opera bettiana
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