196,667 research outputs found
Temporal patterns of eye movements reflect the complexity of a mental image
No full textEye movements during mental imagery show a distinctive spatial and temporal pattern. While it has been known for a long time that fixation locations during mental imagery resemble those during perception, we showed in a recent study (Gurtner et al., 2019) that the temporal dynamics of fixations differ between perception and mental imagery. Using recurrence quantification analysis, we found that eye fixations return more often and sooner to previously inspected areas during mental imagery than during perception.
To further investigate this difference we analyzed the role of re-fixations for maintaining mental images. In two experiments, we tested the hypothesis that systematic re-visits of a limited number of locations can counteract fading of the imagined content. In the first experiment, we manipulated the demands of maintenance by increasing the complexity of the pattern that needed to be maintained. In a second experiment, dynamic visual noise interfered with the mental image. The results contribute to a better understanding of eye movements during mental imagery by including the temporal dynamics of fixations in addition to spatial congruence.
Gurtner, L. M., Bischof, W. F., & Mast, F. W. (2019). Recurrence quantification analysis of eye movements during mental imagery.
Journal of Vision, 19(17), doi:10.1167/19.1.1
Katapetasma: Lexicographical and etymological considerations on the Biblical veil / Daniel M. Gurtner.
No full textAn empirically grounded agent based simulator for the air traffic management in the SESAR scenario
No full textIn this paper we present a simulator allowing to perform policy experiments relative to the air traffic management. Different SESAR solutions can be implemented in the model to see the reaction of the different stakeholders as well as other relevant metrics (delay, safety, etc). The model describes both the strategic phase associated to the planning of the flight trajectories and the tactical modifications occurring in the en-route phase. An implementation of the model is available as an open-source software and is freely accessible by any user. More specifically, different procedures related to business trajectories and free-routing are tested and we illustrate the capabilities of the model on an airspace which implements these concepts. After performing numerical simulations with the model, we show that in a free-routing scenario the controllers perform less operations but the conflicts are dispersed over a larger portion of the airspace. This can potentially increase the complexity of conflict detection and resolution for controllers. In order to investigate this specific aspect, we consider some metrics used to measure traffic complexity. We first show that in non-free-routing situations our simulator deals with complexity in a way similar to what humans would do. This allows us to be confident that the results of our numerical simulations relative to the free-routing can reasonably forecast how human controllers would behave in this new situation. Specifically, our numerical simulations show that most of the complexity metrics decrease with free-routing, while the few metrics which increase are all linked to the flight level changes. This is a non-trivial result since intuitively the complexity should increase with free-routing because of problematic geometries and more dispersed conflicts over the airspace
Direct p53 transcriptional repression: In vivo analysis of CCAAT-containing G2/M promoters
No full textIn response to DNA damage, p53 activates G1/S blocking and apoptotic genes through sequence-specific binding. p53 also represses genes with no target site, such as those for Cdc2 and cyclin B, key regulators of the G2/M transition. Like most G2/M promoters, they rely on multiple CCAAT boxes activated by NF-Y, whose binding to DNA is temporally regulated during the cell cycle. NF-Y associates with p53 in vitro and in vivo through the alpha C helix of NF-YC (a subunit of NF-Y) and a region close to the tetramerization domain of p53. Chromatin immunoprecipitation experiments indicated that p53 is associated with cyclin B2, CDC25C, and Cdc2 promoters in vivo before and after DNA damage, requiring DNA-bound NF-Y. Following DNA damage, p53 is rapidly acetylated at K320 and K373 to K382, histories are deacetylated, and the release of PCAF and p300 correlates with the recruitment of histone deacetylases (HDACs)-HDAC1 before HDAC4 and HDAC5 and promoter repression. HDAC recruitment requires intact NF-Y binding sites. In transfection assays, PCAF represses cyclin B2, and a nonacetylated p53 mutant shows a complete loss of repression potential, despite its abilities to bind NF-Y and to be recruited on G2/M promoters. These data (i) detail a strategy of direct p53 repression through associations with multiple NF-Y trimers that is independent of sequence-specific binding of p53 and that requires C-terminal acetylation, (ii) suggest that p53 is a DNA damage sentinel of the G2/M transition, anti (iii) delineate a new role for PCAF in cell cycle control
ELSA Air Traffic Simulator: an Empirically grounded Agent Based Model for the SESAR scenario
No full textThis paper describes the Air Traffic Simulator produced by the ELSA project. It is partially based on interacting agents taking actions during strategic and tactical phases: air
companies, network manager, pilots, and controllers. The simulator is highly modular and each part can be used independently
of the others. The code is open source, ready to use and available for the research community.
Some results concerning the future organization of the European Airspace (free-routing) are presented, using the full capabilities of the model. We found that the implementation of free-routing could have a positive impact on the safety event occurrences that will be reduced in number although spread
over a larger area. The controllers behaviour will therefore move to a situation where they have to perform a smaller number
of operations dispersed over a larger portion of the airspace. We also show that the number of operations performed by a
controller quadratically depends from the number of aircraft present in the considered airspace and that such quadratic scaling
law is modified when the airspace is partitioned in air traffic sectors with capacity constraints
Shared Decision Making in the Psychiatric Inpatient Setting: An Ethnographic Study about Interprofessional Psychiatric Consultations
No full textShared decision making is increasingly receiving attention in health care and might improve both the quality of care and patient outcomes. Nevertheless, due to its complexity, implementation of shared decision making in clinical practice seems challenging. This ethnographic study aimed to gain a better understanding of how psychiatric inpatients and the interprofessional care team interact during regular interprofessional psychiatric consultations. Data were collected through participant observation on two different psychiatric wards in a large psychiatric hospital in Switzerland. The observation focused on the contextual aspects of interprofessional patient consultations, the communication and interaction as well as the extent to which patients were involved in decision making. Participants included patients, psychiatrists, junior physicians, nurses, psychologists, social workers and therapists. We observed 71 interprofessional psychiatric consultations and they differed substantially in both wards in terms of context (place and form) and culture (way of interacting). On the contrary, results showed that the level of patient involvement in decision making was comparable and depended on individual factors, such as the health care professionals' communication style as well as the patients' personal initiative to be engaged. The main topics discussed with the patients related to pharmacotherapy and patient reported symptoms. Health care professionals in both wards used a rather unidirectional communication style. Therefore, in order to promote patient involvement in the psychiatric inpatient setting, rather than to focus on contextual factors, consultations should follow a specific agenda and promoting a bidirectional communication style for all parties involved is strongly recommended
1999 Twin Pines Cooperative Composite Photograph
No full textM. Allen; R. Antonek; H. Bender; R. Blankman; T. Bowman; C. Chastain; A. Coburn; S. Donahue; M. Fecher; J. Gadd; L. Gurtner; N. Gurtner; B. Harrington; A. Herron; C. Kaiser; E. Maurer; D. McFarren; P. Morton; L. Nikirk; J. Rogers; J. Smith; K. Snyder; A. Sparks; M. Strain; C. Taylor; J. Tilton; K. Yeoma
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
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