631 research outputs found

    Properties of AlyGa1-yN/AlxGa1-xN/AlN/GaN Double-Barrier High Electron Mobility Transistor Structure

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    Electrical properties of AlyGa1-yN/AlxGa1-xN/AlN/GaN structure are investigated by solving coupled Schrodinger and Poisson equation self-consistently. Our calculations show that the two-dimensional electron gas (2DEG) density will decrease with the thickness of the second barrier (AlyGa1-yN) once the AlN content of the second barrier is smaller than a critical value y(c), and will increase with the thickness of the second barrier (AlyGa1-yN) when the critical AlN content of the second barrier y(c) is exceeded. Our calculations also show that the critical AlN content of the second barrier y(c) will increase with the AlN content and the thickness of the first barrier layer (AlxGa1-xN)

    Modification of nitrile rubber 2980 with liquid nitrile rubber YN 25

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    Nitrile rubber (NBR) 2980 M was prepared by mechanical blending of liquid nitrile rubber (YN 25) into NBR 2980. The effect of YN 25 addition ratio on the Mooney viscosity, hardness, vulcanization characteristics of NBR 2980 M compound, and tensile properties of NBR 2980 M vulcanizate were studied. The results showed that with the increase of YN 25, Mooney viscosity, modulus at 300% at 50 min, tensile strength, maximum and minimum torque of NBR 2980 M all decreased li-nearly, while the elongation at break and three torque differences vulcanization times of 25 min, 50 min, and 90 min all increased linearly. However, the change in hardness of the compound was not significant. For increase in mass fraction of YN 25 in NBR 2980 M by 1%, Mooney viscosity of the compound decreases by 0.78, and the modulus at 300%, tensile strength, maximum and minimum torque of the vulcanizate decrease by 0.25 MPa, 0.17 MPa, 0.12 dN·m, and 0.02 dN·m, respectively. The elongation at break and three vulcanization times of 25 min, 50 min, and 90 min increase by 4.1%, 0.05 min, 0.08 min, and 0.18 min, respectively

    Role of Cellular Senescence Genes and Immune Infiltration in Sepsis and Sepsis-Induced ARDS Based on Bioinformatics Analysis

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    Xiao-ling Wu, Ya-nan Guo Intensive Care Unit, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence: Ya-nan Guo, Intensive Care Unit, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Wuhan, 430014, People’s Republic of China, Tel +86-18186120762, Fax +86-27-82811446, Email [email protected]: Sepsis is the leading cause of death in critically ill patients; it results in multiorgan dysfunction, including acute respiratory distress syndrome (ARDS). Our study was conducted to determine the role of cellular senescence genes and immune infiltration in sepsis and sepsis-induced ARDS via bioinformatic analyses.Experimental Procedures: Datasets GSE66890 and GSE145227 were obtained from the Gene Expression Omnibus (GEO) database and utilized for bioinformatics analyses. Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of the differentially expressed genes (DEGs) were performed to identify the key functional modules. Two machine learning algorithms, least absolute shrinkage and selection operator (LASSO) and support vector machine recursive feature elimination (SVM-RFE), were used to screen for characteristic genes in sepsis and sepsis-induced ARDS. ROC curves were generated to evaluate the predictive ability of gene hubs. Differences in immune infiltration levels between the disease and control groups were compared via ssGSEA. The diagnostic value of the hub genes was verified via quantitative PCR (qPCR) in hospitalized patients.Results: Four characteristic genes (ATM, CCNB1, CCNA1, and E2F2) were identified as biomarkers for the progression of sepsis-induced ARDS. E2F2 showed the highest predictive ability for the occurrence of ARDS in patients with sepsis. CD56bright and plasmacytoid dendritic cells exhibited high infiltration in the sepsis-induced ARDS group, whereas eosinophils, MDSCs, macrophages, and neutrophils exhibited low infiltration. In addition, ATM expression was lower in patients with sepsis than in those without sepsis (n = 6).Conclusion: Sepsis-induced ARDS is correlated with circulating immune responses, and the expression of ATM, CCNB1, CCNA1, and E2F2 may serve as potential diagnostic biomarkers and therapeutic targets in sepsis-induced ARDS.Keywords: sepsis, cellular senescence genes, immune infiltration, acute respiratory distress syndrome, bioinformatics analysi

    FOURIER TRANSRORM EMISSION SPECTROSCOPY OF THE A1ΣX1ΣA^{1}\Sigma^{-}- X^{1}\Sigma^{-} SYSTEM OF YN.

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    Author Institution: Department of Chemistry, University of Arizona; Department of Chemistry, University of WaterlooThe electronic emission spectrum of YN has been observed in the 2.3-2.6 μ\mu spectral region using a Fourier transform spectrometer. The bands were excited in a yurium hollow cathode lamp in the presence of a trace of molecular nitrogen. The observed bands, with origins at 3882.7625(4), 4229.0457(3), 4528. 6562(46), 4798.5145(13), 5049.4429(20) and 5281.2129(27)cm1 cm^{-1}, have been assigned as the 0-0, 1-1, 3-3, 4-4 and 5-5 vibrational bands, respectively, of the A1Σ+X1Σ+A {^{1}\Sigma^{+}} - X {^{1} \Sigma^{+}} electronic transition. The principal equilibrium constants for the ground state obtained from this analysis are Be=0.42815(24)cm1re=1.80405(50)B_{e}{^{\prime\prime}} = 0.42815(24) cm^{-1} r_{e}{^{\prime\prime}}=1.80405(50) {\AA} and the corresponding excited state values are Be=0.42311(30)cm1B_{e}^{\prime}=0.42311(30) cm^{-1} and re=1.81477(64)r_{e}=1.81477(64) {\AA}. This work represents the first observation of the YN molecule

    Arrenurus (Arrenurus) pseudodistinctus Zheng & Guo & Zhang 2022, sp. nov.

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    Arrenurus (Arrenurus) pseudodistinctus sp. nov. (Figs 3–6) Material examined. Holotype male, GUGC, Slide No. JL-AR-2019072301, Baicheng City, Jilin Province, P. R. China (45°37′46″N, 122°50′43″E; alt. 150 m), 23-VII-2019, Haitao Li leg.. Paratypes, 8/6/0, Slide No. JL-AR-2019072302–JL-AR-2019072310 (same data as holotype); Slide No. YN-AR-2018081110–YN-AR-2018081113, Mengla County, Yunnan Province P. R. China (101°06′28″N, 21°08′43″E), 11-VIII-2018, Zhuhui Ding leg.. 8/5/0. Diagnosis. Petiole widest in the middle and with two hyaline appendages; hyaline membrane small trapezoid. Description. Male (n=16; Figures 3–4): Idiosoma L 957 (957–1027) (including petiole), W 792 (792–817), L/W ratio 1.21 (1.21–1.26) (Fig. 3A). Anterior margin of idiosoma slightly concave (Fig. 3A). Dorsal furrow incomplete, reaching to base of the pygal lobes; anterior margin of dorsal shield convex, dorsal shield W 483 (468–491); D 1 to D 4 almost on an oblique line, D 3 and D 4 on humps; dorsal humps well developed, and pointing towards anterior of idiosoma (Fig. 3A, C). A cuticular structure and a pair of small humps between D 4 and the petiole, and the former V-shaped (Fig. 3A). Pygal lobes well developed (Fig. 3A). Petiole well-developed, L 165 (165–182), widest in the middle; petiole with two hyaline appendages; hyaline membrane small trapezoid (Fig. 3A). The posterior margin of the idiosoma with a triangular extension, covering the base of the petiole (Fig. 3A). Cx-I and Cx-II extending well beyond the anterior margin of the idiosoma; medial margin of Cx-IV twice the length of Cx-III (Fig. 3B). ACG medium L 264 (259–269); PCG medium L 306 (298–311); Gb–Cx-IV 457 (449–457); Gb–Gp 547 (547–594); Gb–Ep 640 (635–683); Ap enlarged medially, extending to lateral margins of idiosoma, lateral parts narrower (Fig. 3B). L of palp segments: P-I 39 (31–39), P-II 90 (89–99), P-III 73 (72–79), P-IV 116 (116–121), P-V 55 (53–59) (Fig. 3D); P-2 without (or: 0–4) ventral setae; L of leg segments: L of I-L-1–6: 66 (65–68), 138 (139–148), 155 (145–155), 185 (184–187), 176 (176–186), 223 (223–238) (Fig. 4A); L of II-L-1–6: 88 (79–88), 153 (142–160), 169 (156–169), 212 (209–215), 207 (207–222), 266 (254–266) (Fig. 4B); L of III-L-1–6: 104 (104–115), 177 (177–187), 155 (155–167), 215 (194–219), 216 (205–216), 225 (190–225) (Fig. 4C); L of IV-L-1–6: 161 (153–161), 260 (196–260), 193 (190–207), 270 (240–270), 149 (149–164), 209 (201–218) (Fig. 4D); IV-l-4 with a spur. Female (n=11; Figures 5–6): Idiosoma L 1289 (1289–1354), W 1165 (1165–1198), L/W ratio 1.11 (1.11–1.13) (Fig. 5A); dorsal furrow complete, dorsal shield L 1025 (1013–1065), W 865 (856–872); Dorsal humps absent (Fig. 5A). Cx-I and Cx-II not extending beyond anterior margin of idiosoma; Cx-IV almost without a medial margin; ACG medium L 261 (256–261); PCG medium L 314 (292–314); Gb–Cx-IV 424 (404–448); Gb–Gp 487 (485–498); Gb–Ep 950 (950–973) (Fig. 5B). Ap slightly bowed (Fig. 5B). Gp L 147 (147–161), W 177 (168–185); L of palp segments: P-I 41 (40–46), P-II 76 (76–102), P-III 84 (74–90), P-IV 134 (126–134), P-V 51 (44–55) (Fig. 5C), P-II with two (or: 1–3) ventral setae; L of leg segments: L of I-L-1–6: 70 (70–72), 128 (128–134), 137 (137–147), 185 (184–188), 180 (175–184), 182 (182–198) (Fig. 6A); L of II-L-1–6: 72 (72–77), 152 (151–158), 158 (158–163), 213 (197–216), 216 (199–216), 215 (209–215) (Fig. 6B); L of III-L-1–6: 87 (87–93), 154 (154–162), 164 (147–164), 213 (208–216), 210 (202–210), 216 (186–216) (Fig. 5C); L of IV-L-1–6: 142 (142–154), 212 (199–229), 218 (204–218), 287 (276–287), 229 (229–244), 260 (246–260) (Fig. 6D). Habitat. Inhabiting a lentic pool in the stream bed with dead branches and rotten leaves. Distribution. China (Jilin, Yunnan). Etymology. “ Pseudo- ” means false; the news species is named after its similar species, Arrenurus (Arrenurus) distinctus Marshall, 1919. Remarks. The new species is close to Arrenurus (Arrenurus) distinctus Lundblad, (1969). However, the new species differs from A. (A.) distinctus in the following points, particularly in the male: (1) With hyaline membrane in the new species, but without in A. (A.) distinctus; (2) Ligulate process well-developed in the new species, but relatively short in A. (A.) distinctus; (3) Cx-I and Cx-II much extending beyond anterior idiosoma margin in the new species, but not in A. (A.) distinctus . The new species is similar to Arrenurus (Arrenurus) kantakaphorus Cook, 1967 (Cook 1967) collected from India, but they differ from each other by the following: (1) The petiole is shorter (165–182) in the new species, but longer (319) in A. (A.) kantakaphorus. (2) petiole with two hyaline appendages in the new species, but with a spoonshaped central piece in A. (A.) kantakaphorus. Also, the new species is similar to Arrenurus (Arrenurus) confinis Lundblad, 1969 (Lundblad 1969). However, the new species differs from A. (A.) confinis in the following points: (1) The petiole has no setae in the new species, but has a pair of setae in A. (A.) confinis . (2) Hyaline membrane small and trapezoid in the new species, but bigger in A. (A.) confinis .Published as part of Zheng, Yulin, Guo, Jianjun & Zhang, Runzhi, 2022, Three new and two newly recorded species of the water mite genus Arrenurus Dugès, 1834 (Acari, Hydrachnidia: Arrenuridae) from China, pp. 55-72 in Zootaxa 5174 (1) on pages 58-62, DOI: 10.11646/zootaxa.5174.1.4, http://zenodo.org/record/697305

    Généralisation de l'identité de Scott sur les permanents

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    AbstractThe Scott identity on permanents is reproved and generalized by means of a recent theorem due to Lascoux. For example, the following result is derived: let x1,…,xn and y1,…,yn be the roots of the polynomials xn−1 and yn+y−1, respectively. Then the permanent of the matrix (1/(xi−yj)) is equal to nn

    Integral representation of Markov systems and the existence of adjoined functions for Haar spaces

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    AbstractLet A be a set of real numbers, and let Yn: = {y0,…, yn} be a C̆ebys̆ev system on A. Assume, moreover, that if inf A or sup A belongs to A, then it is a point of accumulation of A at which all yj are continuous. We find necessary and sufficient conditions for the existence of a function yn + 1 such that also {y0,…, yn, yn + 1} is a C̆ebys̆ev system on A. This theorem generalizes earlier results of Zielke and of the author. The proof is based on an integral representation of Markov systems that slightly extends a previous result of Zielke

    Arylchlorocarbenes in the synthesis of heterocycles containing two nitrogen atoms

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    Substituted pyrazoles and pyrrolo[1,2-c]pyrimidines were prepared from the reaction of arylchlorocarbenes with 1,2-diazabuta-1,3-dienes and 4-vinylpyrimidines, respectively.PT: J; CR: ATTANASI A, 1998, J ORG CHEM, V63, P9880 ATTANASI OA, 1977, SYNLETT, P1128 ATTANASI OA, 1999, TETRAHEDRON LETT, V40, P3891 BONINI BF, 1981, J CHEM SOC P1, P2322 BONNEAU R, 1999, J PHOTOCH PHOTOBIO A, V126, P31 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 KUEHNE ME, 1964, J ORG CHEM, V29, P1582 LIU MTH, 1994, INT J CHEM KINET, V26, P1179 MAIBORODA DA, 1997, J ORG CHEM, V62, P7100 MINGUEZ JM, 1996, J ORG CHEM, V61, P4655 MOYANO EL, 1998, J ORG CHEM, V63, P8188 OVERBERGER CG, 1954, J AM CHEM SOC, V76, P1879 PERKAMPUS HH, 1972, TETRAHEDRON, V28, P2099 ROMASHIN YN, 1999, CHEM COMMUN 0307, P447 ROMASHIN YN, 1999, TETRAHEDRON LETT, V40, P7163 WONG JL, 1965, J ORG CHEM, V30, P2398; NR: 16; TC: 6; J9: CHEM COMMUN; PG: 2; GA: 324XFSource type: Electronic(1
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