353 research outputs found
Histologic and histomorphometric analysis of bone regeneration with bovine grafting material after 24 months of healing. A case report
No full textAnorganic bovine bone mineral matrix (ABBMM) has been reported to have osteoconductive properties and no inflammatory or adverse responses when used as grafting material in sinus augmentation procedures. However, controversy remains in regard to degradation rate of ABBMM. The aim of this study was to histologically and histomorphometrically evaluate the degradation of ABBMM in human bone samples obtained in one patient 24 months after sinus augmentation. Materials and Methods: The histologic and histomorphometric analysis was performed by means of light microscopy in three specimens harvested from the same patient, Results: After 24 months the tissue pattern appeared to be composed of residual particles, some in close contact with the newly formed bone, others separated by translucent areas and osteoid tissues. Newly-formed bone presented different levels of maturation and numerous osteocytes, with greater numbers in bone closer to the grafted particles (27.3% vs. 11.2%, p < 0.05). The histomorphometric analysis showed mean values of 40.84% newly-formed bone, 33.58% residual graft material, 23.84% marrow spaces, and 1.69% osteoid tissue, Conclusions: Even though ABBMM underwent considerable resorption, a great amount of residual grafting material was still present after two years of healing following sinus augmentation. This study confirms that the bovine grafts can be classified as long-term degradation materials
La giustizia come servizio ai cittadini: il caso delle best practices
No full textLa crescita della rilevanza sociale e politica della giustizia nelle democrazie contemporanee è un dato ormai assodato. È forse meno evidente come tale crescita induca a sua volta sul sistema giudiziario una pressione da parte dell’ambiente. Infatti, la domanda di giustizia tende ad aumentare non tanto in termini quantitativi – più casi si indirizzano al sistema giudiziario – quanto dal punto di vista qualitativo: nuovi e più ampi ambiti di attività umana chiedono di essere regolati dall’intervento giudiziario. Ma non solo ci si aspetta di più dall’amministrazione della giustizia, ci si aspetta anche quello che fa lo faccia meglio, cioè che migliori il suo rendimento. Si tratta di una tendenza destinata a non mutare, almeno a breve termine, e che ha investito gran parte dei paesi democratici e, fra questi, anche l’Italia. Dare risposta a queste nuove domande diventa un compito ineludibile, pena una grave crisi di legittimità degli apparati giudiziari. Organizzare una risposta efficace richiede però che i sistemi giudiziari siano disponibili ad introdurre profonde innovazioni nel loro operare
Comparative results of single implants with and without laser-microgrooved collar placed and loaded with different protocols: a long-term (7 to 10 years) retrospective multicenter study
No full textPURPOSE: This nonrandomized, retrospective multicenter study aimed to evaluate success rates, peri-implant marginal bone loss, and clinical parameters around single implants with and without laser-microgrooved collars placed and loaded using different protocols after 7 to 10 years of function. MATERIALS AND METHODS: A chart review was used to select patients treated at five private dental clinics with single dental implants with and without laser-microgrooved collars. Cumulative success rates, peri-implant marginal bone loss, probing depth, Plaque Index, bleeding on probing, and gingival recession were recorded at baseline examinations (ie, definitive restoration delivery) and at each year during the follow-up period. RESULTS: Three hundred single implants (140 without laser-microgrooved collars and 160 with 1.7-mm laser-microgrooved collars) in 300 patients were selected. At the completion of the study period, 26 patients and 26 implants (17 with and 9 without a laser-microgrooved collar) were classified as "dropouts." Implants and restorations were categorized into two subgroups each for a total of four study groups: group 1, immediate implant placement; group 2, delayed implant placement; group 3, immediate nonocclusal loading of prostheses; and group 4, delayed loading of prostheses. Nineteen implants (6.9%) failed clinically (4 [2.7%] with and 15 [11.4%] without a laser-microgrooved collar). The difference in cumulative success rates was statistically significant (P < .05). Radiographically, at the end of the follow-up period, the laser-microgrooved group showed a mean peri-implant marginal bone loss of 0.64 mm compared with 1.82 mm for the non-laser-microgrooved group. At the same time point, a mean probing depth of 0.76 mm was observed for the laser-microgrooved group compared with 2.75 mm for the non-laser-microgrooved group. A statistically significant difference in peri-implant marginal bone loss and probing depth between the two types of implant collars was evident (P < .05). No statistically significant correlation was noted between the types of implant placement/prosthetic restoration and clinical parameters. CONCLUSION: Implants with a laser-microgrooved collar appear to influence the peri-implant soft and hard tissue stability, reducing the probing depth levels and the peri-implant marginal bone loss by more than 50% after 10 years of function, regardless of the type of implant placement and loading protocol
Implants with a laser-microgrooved Collar Placed in Grafted Posterior Maxillary Extraction Sockets and in Crestally Grafted Sinuses: a 5-Year Multicentre Retrospective Study
No full textThe aim of this retrospective multicentre cohort study was to compare clinical outcomes, soft tissues conditions and differences in marginal bone loss between implants with a laser-microgrooved collar placed in posterior maxillary extraction sockets grafted by 4 to 5 months, and in posterior maxillary pristine bone (spontaneously healed posterior maxillary extraction sockets) by means of osteotome-mediated sinus floor elevation, over a period of 5 years after functional loading
Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study
No full textObjectives: The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous healing.
Material and Methods: Thirty patients were enrolled in the present study and underwent single-tooth extraction in the premolar/molar areas. Ten sites were grafted with porcine-derived bone covered by collagen membrane, 10 covered by porcine-derived collagen membrane alone, and 10 underwent natural spontaneous healing. Vertical and horizontal bone changes after 3-month were evaluated at implant placement.
Results: The vertical and horizontal bone changes at the extraction sockets treated with collagen membrane alone (vertical: -0.55 [SD 0.11] mm, and horizontal: -1.21 [SD 0.69] mm) and collagen membrane plus porcine-derived bone (vertical: -0.37 [SD 0.7] mm, and horizontal: -0.91 [SD 0.53] mm) were found significantly lower (P < 0.001), when compared to non-grafted sockets (vertical: -2.09 [SD 0.19] mm, and horizontal: -3.96 [SD 0.87] mm).
In type 1 extraction sockets, in premolar sites, and in presence of vestibular bone thicknesses ≥ 1.5 mm, the use of collagen membrane alone revealed similar outcomes to those with additional graft material.
Conclusions: At the re-entry surgery, extraction sockets grafted with porcine-derived bone and covered by collagen membrane, and extraction sockets covered by porcine-derived collagen membrane alone, showed significantly lower vertical and horizontal bone changes, compared to extraction sockets sites underwent natural spontaneous healing. However, a complete prevention of remodelling is not achievable, irrespective of the technique used
Effectiveness of Xenograft and Porcine-Derived Resorbable Membrane in Augmentation of Posterior Extraction Sockets with a Severe Wall Defect. A Radiographic/Tomographic Evaluation
No full textObjectives: The aim of the present prospective study was to evaluate, by means of intraoral periapical radiographs and cone-beam computed tomography, hard tissue changes after ridge augmentation procedures in posterior extraction sockets with severe wall defects.
Material and Methods: Twenty patients, with a non-restorable premolar/molar tooth and severe wall defect, were enrolled in the present study, and underwent single-tooth extraction. Extraction sites were grafted with porcine-derived bone covered by porcine-derived collagen membrane. Intraoral periapical radiographs and cone-beam computed tomography scans, obtained at enrolment, and 6 months after ridge augmentation procedures were analysed and compared.
Results: In the intraoral periapical radiographs, mean vertical bone gains detected at the distal, central and mesial aspects of the extraction sockets were 3.5 (SD 1.1) mm, 8.2 (SD 2.1) mm, and 3.9 (SD 1.7) mm, respectively. In the cone-beam computed tomography scans, the mean vertical bone gains detected at the more vestibular and more palatal aspects were 4.4 (SD 1.9) mm, and 3.3 (SD 2.8) mm, respectively. The mean horizontal bone gain was 3.5 (SD 1.6) mm. In all examined defects, mean vertical and horizontal bone levels showed a statistically significant increase (P < 0.05) at 6 months after extraction.
Conclusions: Within the limits of this study, the results suggest that porcine-derived bone graft covered by a collagen membrane can support significant vertical and horizontal bone gain at posterior post-extraction sockets with severe wall defects
Histologic evaluation of bone healing of adjacent alveolar sockets grafted with bovine- and porcine-derived bone: a comparative case report in humans
No full textTo evaluate and compare histomorphometrically the bone response to two xenografts, one bovine and the other porcine, grafted in adjacent extraction sockets in a human. In this case report, two adjacent maxillary premolars were extracted, and the sockets were filled with two different xenogeneic bone substitutes (first premolar with bovine bone, and second premolar with porcine bone) to counteract post-extraction volume loss. Following 6 months bone core specimens were harvested during the placement of implants at the regenerated sites. Histomorphometrically, for the bovine xenograft the percentage of newly formed bone (osteoid) was 26.85%, the percentage of the residual graft material was 17.2% and the percentage of connective tissue 48.73%, while for the porcine xenograft, newly formed bone (osteoid) represented 32.19%, residual graft material was 6.57% and non-mineralized connective tissue was 52.99%. Histological results indicated that both biomaterials assessed in this study as grafts for socket preservation technique are biocompatible and osteoconductive. Bovine bone derived demonstrated to be less resorbable than porcine bone derived. Both xenogenic biomaterials did not interfere with the normal bone reparative processe
Calcium sulfate in human extraction sockets healing. Clinical and histological observations in 10 cases
No full textClinical, radiographic, and esthetic evaluation of immediately loaded laser microtextured implants placed into fresh extraction sockets in the anterior maxilla: a 2-year retrospective multicentric study.
No full textObjectives:To assess the clinical, radiographic, and esthetic outcomes of implants with a laser microtextured collar placed in the anterior region of the maxilla at the time of tooth extraction and immediately temporized.Methods:Forty-six Tapered Internal Laser-Lok BioHorizons implants were immediately placed and immediately restored with nonfunctional loading in 46 patients (24 men and 22 women) with a thick gingival biotype, ideal gingival level/contour, and postextraction intact walls. Survival rate, cortical bone loss, and periimplant mucosal responses were evaluated at 6, 12, and 24 months.Results:Survival rate was 95.6%. Mean mesial and distal marginal bone loss, 24 months after installation, were 0.58 mm (SD = 0.53; range, 0.17-1.15) and 0.57 mm (SD = 0.70; range, 0.42-1.10), respectively. A mesial and distal papilla regrowth mean of 1.8 and 1.5 mm, respectively, were found. The midfacial soft tissue levels showed 0.12 mm of mean recession after 24 months.Conclusion:Immediate implants with a laser microtextured surface restored at the day of surgery, may be considered as a predictable procedure in terms of implant survival and hard and soft tissue remodeling.OBJECTIVES: To assess the clinical, radiographic, and esthetic outcomes of implants with a laser microtextured collar placed in the anterior region of the maxilla at the time of tooth extraction and immediately temporized.
METHODS: Forty-six Tapered Internal Laser-Lok BioHorizons implants were immediately placed and immediately restored with nonfunctional loading in 46 patients (24 men and 22 women) with a thick gingival biotype, ideal gingival level/contour, and postextraction intact walls. Survival rate, cortical bone loss, and periimplant mucosal responses were evaluated at 6, 12, and 24 months.
RESULTS: Survival rate was 95.6%. Mean mesial and distal marginal bone loss, 24 months after installation, were 0.58 mm (SD = 0.53; range, 0.17-1.15) and 0.57 mm (SD = 0.70; range, 0.42-1.10), respectively. A mesial and distal papilla regrowth mean of 1.8 and 1.5 mm, respectively, were found. The midfacial soft tissue levels showed 0.12 mm of mean recession after 24 months.
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