23,642 research outputs found
Die ökonomische Attraktivität von Sportligen aus der Perspektive der Spieler
No full texteingereicht von Daniel Gruber BSc.Literaturverzeichnis: Seite 67-70Masterarbeit Paris Lodron-Universität Salzburg 2016Abstract in englischer Sprach
Handbüchlein etlicher Fragen : Aus welchem zu mehrern Verstand des H. Catechismi/ die Knaben und Jugend in der Kirchen/ Schulen/ und daheime nützlich unterrichtet und geübet werden können / Zu dem Ende also zusammen gezogen und unterschieden/ Durch M. Danielem Mönchmeyern ...
No full textTítulo: Institutiones Juris Ecclesiatici Latinas reddidit & cum Animadversionibus Justi Henningi Boehmeri ...
No full textHay edicións desta obra en francés dos anos 1677 e 1679 a nome de Ch. Bone
Vivian. R. Gruber, The Royal Provincial Intendants. A Governing Elite in Eighteenth Century France, 1968
No full textRoche Daniel. Vivian. R. Gruber, The Royal Provincial Intendants. A Governing Elite in Eighteenth Century France, 1968. In: Dix-huitième Siècle, n°3, 1971. pp. 393-394
The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.
No full textCiliopathies are a group of developmental disorders that manifest with multi-organ anomalies. Mutations in TMEM67 (MKS3) cause a range of human ciliopathies, including Meckel-Gruber and Joubert syndromes. In this study we describe multi-organ developmental abnormalities in the Tmem67(tm1Dgen/H1) knockout mouse that closely resemble those seen in Wnt5a and Ror2 knockout mice. These include pulmonary hypoplasia, ventricular septal defects, shortening of the body longitudinal axis, limb abnormalities, and cochlear hair cell stereociliary bundle orientation and basal body/kinocilium positioning defects. The basal body/kinocilium complex was often uncoupled from the hair bundle, suggesting aberrant basal body migration, although planar cell polarity and apical planar asymmetry in the organ of Corti were normal. TMEM67 (meckelin) is essential for phosphorylation of the non-canonical Wnt receptor ROR2 (receptor-tyrosine-kinase-like orphan receptor 2) upon stimulation with Wnt5a-conditioned medium. ROR2 also colocalises and interacts with TMEM67 at the ciliary transition zone. Additionally, the extracellular N-terminal domain of TMEM67 preferentially binds to Wnt5a in an in vitro binding assay. Cultured lungs of Tmem67 mutant mice failed to respond to stimulation of epithelial branching morphogenesis by Wnt5a. Wnt5a also inhibited both the Shh and canonical Wnt/β-catenin signalling pathways in wild-type embryonic lung. Pulmonary hypoplasia phenotypes, including loss of correct epithelial branching morphogenesis and cell polarity, were rescued by stimulating the non-canonical Wnt pathway downstream of the Wnt5a-TMEM67-ROR2 axis by activating RhoA. We propose that TMEM67 is a receptor that has a main role in non-canonical Wnt signalling, mediated by Wnt5a and ROR2, and normally represses Shh signalling. Downstream therapeutic targeting of the Wnt5a-TMEM67-ROR2 axis might, therefore, reduce or prevent pulmonary hypoplasia in ciliopathies and other congenital conditions
Report on Meteorological Research March 1, 1935 (m-1)
No full textThe object of the report was to elucidate in detail the various features of the research program in meteorology being carried on at the Daniel Guggenheim Airship Institute in Akron, Ohio. Mr. L. J. Fangman, of the U.S. Weather Bureau, was collaborating with the author in carrying out work such as a study of autographic records of the various meteorological elements during frontal passages with a view to the possible prediction of the intensity of the accompanying disturbance as it may affect the operation of aircraft and a study of atmospheric gustiness with a view to finding the dependence between frequency end amplitude of velocity fluctuations and the vertical temperature and velocity gradients
(Fourth) Report on Meteorological Activities at the DGAI (8-1-36)(Weather Bureau Copy)
No full textThis report is on the investigations of frontal phenomena at the Daniel Guggenheim Airship Institute in Akron, Ohio from January 1, 1935 through August 1, 1936. The investigation was carried out with the cooperation of the U.S. Bureau of Aeronautics, the U.S. Weather Bureau, the California Institute of Technology, and the Guggenheim Airship Institute. Mr. R.C. Robinson of the Weather Bureau cooperated with the author in carrying out the investigation. The object of the investigation was to determine the intensity of the atmospheric disturbances (i.e. rapidity of wind shift and gustiness) accompanying the passage of cold fronts, along with a study of the characteristics of the air masses involved and other features which might affect the intensity of the disturbance. The report treated thirty cold fronts which passed the station during 1935 to 1936
Archives and Images as Repositories of Time, Language, and Forms from the Past: A Conversation with Daniel Eisenberg
No full textReplication Data for: "It's Good to be First: Order Bias in Reading and Citing NBER Working Papers"
No full textFeenberg, Daniel, Ganguli, Ina, Gaule, Patrick, and Gruber, Jonathan, (2017) "It's Good to be First: Order Bias in Reading and Citing NBER Working Papers." Review of Economics and Statistics 99:1, 32-39
Daniel : Jn einem Sing-Spiel vorgestellet auf dem grossen Braunschweigischen Schau-Platz / [Georg Kaspar Schuermann; Johann Christian Knorr v. Rosenroth]
No full textErm. Komp.: G.K. Schuermann; erm. Textverf.: Joh. Chr. Knorr v. RosenrothVorlageform d. Erscheinungsvermerks: Braunschweig/ In Verlegung Caspar Grubers seel. nachgel. Wittw
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