82 research outputs found
Short- and long-term changes in extracellular glutamate and acetylcholine concentrations in the rat hippocampus following hypoxia
No full textSildenafil citrate has shown to display beneficial cardiovascular effects, suggesting that it may have other systemic benefits involving the endothelium. There is little data regarding the long-term use of this drug and the effects of this on different organs. Objective: The primary aim of this study was to determine whether sildenafil citrate diminishes concentrations of microalbuminuria and percentage of A1c in patients with type 2 diabetes. Design: A double-blind, randomized, controlled trial in 40 male patients, age 35-50, with type 2 diabetes. Subjects received sildenafil citrate 50 mg daily (n = 20) or placebo (n = 20) for 30 days. Levels of hs-CRP, microalbuminuria, homocysteine, A1c and erectile function were measured at baseline and to the end of the study. Results: Men that received sildenafil citrate displayed a significant decrease in the microalbuminuria concentrations (p < 0.01) versus baseline, (p = 0.02) versus placebo and A1c (p < 0.01) versus baseline, (p = 0.01) versus placebo. In addition, we observed a significant increase in the total IIEF score after 30 days of treatment (p < 0.01) versus baseline, (p < 0.01) versus placebo. Conclusions: The administration of 50 mg of sildenafil citrate for 30 consecutive days diminishes microalbuminuria and the percentage of A1c in patients with type 2 diabetes. " 2007 Elsevier Ireland Ltd. All rights reserved.",,,,,,"10.1016/j.diabres.2007.02.006",,,"http://hdl.handle.net/20.500.12104/44533","http://www.scopus.com/inward/record.url?eid=2-s2.0-34548443810&partnerID=40&md5=7d9016ac01744b76a1a70efb5d455957",,,,,,"1",,"Diabetes Research and Clinical Practice",,"13
Raloxifene modifies the insulin sensitivity and lipid profile of postmenopausal insulin resistant women
No full textObjective: To investigate the effects of raloxifene on the insulin sensitivity and lipid profile in insulin-sensitive and insulin-resistant postmenopausal women. Study design: This placebo-controlled, double-blind, randomized study involved 64 postmenopausal women aged between 45 and 55 years. All subjects were screened with the insulin resistance homeostasis model assessment (IR-HOMA) and those patients in the lowest quartile (n = 16) were assigned as insulin sensitive and those in the highest quartile as insulin resistant (n = 16). Patients in both groups received either raloxifene hydrochloride (60 mg/day) or a placebo for a period of 12 weeks. Insulin sensitivity, the serum lipid profile and anthropometric measurements were established before and after therapy. Results: Women with the highest IR-HOMA scores were associated with a significantly higher weight, body mass index, waist and waist-to-hip ratio (p < 0.05). Raloxifene significantly reduced the IR-HOMA scores from 5.76 ± 2.91 to 1.93 ± 0.96 (p = 0.02) and modified the lipid profile in insulin-resistant patients when compared with the placebo group and those patients receiving raloxifene in the insulin-sensitive group. Conclusion: Raloxifene reduced insulin resistance and modified the lipid profile in insulin-resistant postmenopausal women. © 2013 Informa UK Ltd
Radiocarbon age inversions and progression: Source and causes in Late Holocene sediments from Lake Chapala, western Mexico
No full textObjective: To investigate the effects of raloxifene on the insulin sensitivity and lipid profile in insulin-sensitive and insulin-resistant postmenopausal women. Study design: This placebo-controlled, double-blind, randomized study involved 64 postmenopausal women aged between 45 and 55 years. All subjects were screened with the insulin resistance homeostasis model assessment (IR-HOMA) and those patients in the lowest quartile (n = 16) were assigned as insulin sensitive and those in the highest quartile as insulin resistant (n = 16). Patients in both groups received either raloxifene hydrochloride (60 mg/day) or a placebo for a period of 12 weeks. Insulin sensitivity, the serum lipid profile and anthropometric measurements were established before and after therapy. Results: Women with the highest IR-HOMA scores were associated with a significantly higher weight, body mass index, waist and waist-to-hip ratio (p < 0.05). Raloxifene significantly reduced the IR-HOMA scores from 5.76 ± 2.91 to 1.93 ± 0.96 (p = 0.02) and modified the lipid profile in insulin-resistant patients when compared with the placebo group and those patients receiving raloxifene in the insulin-sensitive group. Conclusion: Raloxifene reduced insulin resistance and modified the lipid profile in insulin-resistant postmenopausal women. " 2013 Informa UK Ltd.",,,,,,"10.3109/09513590.2013.788628",,,"http://hdl.handle.net/20.500.12104/44047","http://www.scopus.com/inward/record.url?eid=2-s2.0-84879321401&partnerID=40&md5=a681916948a479c295af6caa196b3c02",,,,,,"7",,"Gynecological Endocrinology",,"67
Author Correction:: The IDEAL framework for surgical robotics: development, comparative evaluation and long-term monitoring (Nature Medicine, (2024), 30, 1, (61-75), 10.1038/s41591-023-02732-7)
No full text\ua9 The Author(s), under exclusive licence to Springer Nature America, Inc. 2024.three authors were missing from The IDEAL Robotics Colloquium. Art Sedrakyan (Weill Cornell Medical College, New York, NY, USA), Joel Horowitz (Maimonides Medical Center, New York, NY, USA) and Arsenio Paez (Centre de Recherche de l’Institut Universitaire de G\ue9riatrie de Montr\ue9al (CRIUGM), Montreal, Quebec, Canada) have all been added in the HTML and PDF versions of the article
Changes in the costs of antihypertensive medications in a developing country: A study in Mexico comparing 1990 and 1996
No full textIn developing countries, the cost of antihypertensive medications is one of the principal limiting factors when trying to treat patients with high blood pressure. To determine the changes in cost (in US dollars) of these medications and in the percentage of the minimum wage needed to purchase them, two cost studies (1990 and 1996) done in Mexico were compared. The yearly cost of a treatment with hydrochlorothiazide was US 10.92. Both figures represent 1.1% of the minimum wage that was in effect at the time. Propranolol hydrochloride cost US 66.12 for the same in 1996. These figures represented, respectively, 4.2% and 6.7% of the minimum wage of 1990 and 1996. The annual cost for nifedipine was US 242.16 in 1996 (24.8% of the minimum wage). The yearly cost of enalapril was US 433.20 in 1996; these costs represented, respectively, 19.4% and 44.2% of the minimum wage. The comparison of these two cost studies (1990 and 1996) shows why Mexico's population is finding it more difficult to purchase antihypertensive medications. Higher costs and reduced purchasing power seem to be the two principal factors causing this. This is probably affecting the population's health, as it is more difficult to control high blood pressure without proper treatment
Sildenafil citrate diminishes microalbuminuria and the percentage of A1c in male patients with type 2 diabetes
No full textSildenafil citrate has shown to display beneficial cardiovascular effects, suggesting that it may have other systemic benefits involving the endothelium. There is little data regarding the long-term use of this drug and the effects of this on different organs. Objective: The primary aim of this study was to determine whether sildenafil citrate diminishes concentrations of microalbuminuria and percentage of A1c in patients with type 2 diabetes. Design: A double-blind, randomized, controlled trial in 40 male patients, age 35-50, with type 2 diabetes. Subjects received sildenafil citrate 50 mg daily (n = 20) or placebo (n = 20) for 30 days. Levels of hs-CRP, microalbuminuria, homocysteine, A1c and erectile function were measured at baseline and to the end of the study. Results: Men that received sildenafil citrate displayed a significant decrease in the microalbuminuria concentrations (p < 0.01) versus baseline, (p = 0.02) versus placebo and A1c (p < 0.01) versus baseline, (p = 0.01) versus placebo. In addition, we observed a significant increase in the total IIEF score after 30 days of treatment (p < 0.01) versus baseline, (p < 0.01) versus placebo. Conclusions: The administration of 50 mg of sildenafil citrate for 30 consecutive days diminishes microalbuminuria and the percentage of A1c in patients with type 2 diabetes. © 2007 Elsevier Ireland Ltd. All rights reserved
Design of strategies to mitigate psychosocial risk in the Author restaurant of the municipality of Los Patios
No full textDigitalLos innumerables retos en los que se encuentran las organizaciones suponen una gran dificultad para lograr ser auto sostenibles en el tiempo. Por ende, es fundamental analizar las variables que establezcan relación de causalidad, que puedan afectar a la salud mental de los trabajadores y, por tanto, la dificultad de las compañías en alcanzar los altos niveles competitivos requeridos en un mundo globalizado.
Entre innumerables variables que afectan a la salud mental de los trabajadores y a las organizaciones, se determinó realizar el análisis de los factores de riesgos psicosociales a los que pueden estar expuestos los trabajadores del Restaurante AUTOR. Asimismo, el análisis se centrará fundamentalmente en los componentes intralaborales, extralaborales y de condiciones de estrés, mediante la aplicación de distintas pruebas que permitirán obtener resultados cuantitativos a fin de establecer el grado de afectación que puedan tener en su salud mental y que pueden dificultar el cumplimiento de los objetivos organizacionales.
Finalmente, fue posible determinar resultados en el análisis de factores de riesgo psicosociales tales como: carga y ritmo del trabajo, relaciones interpersonales, estrés laboral, participación y control, relaciones interpersonales, características de vivienda y entorno, desplazamiento a vivienda y viceversa, situación económica y relaciones familiares, entre otras.1. RESUMEN – (Palabras clave) .................................................................................................. 3
2. ABSTRACT – (Keywords) ........................................................................................................ 3
3. EXPOSICIÓN DE LA TEMÁTICA ........................................................................................ 4
4. DESCRIPCIÓN METODOLÓGICA ...................................................................................... 5
4.1 Tipo de investigación ........................................................................................................ 5
4.2 Variables ............................................................................................................................ 6
4.3 Población y Muestra ......................................................................................................... 6
4.4 Técnicas e instrumentos de recolección de información utilizados .............................. 6
5. ANÁLISIS DIAGNÓSTICO ..................................................................................................... 7
6. ANÁLISIS TÉCNICO ............................................................................................................. 10
6.1 Informe resumido de la ponderación de la aplicación de las tres (3) pruebas descritas anteriormente: ......................................................................................................... 11
6.2 Diseño de graficas de análisis de los datos obtenidos en la prueba del factor de riesgo extralaboral realizado. ............................................................................................................ 12
6.3 Diseño de graficas de análisis de los datos obtenidos en la prueba del factor de riesgo intralaboral realizado. ............................................................................................................. 16
6.4 Diseño de gráficas de análisis de los datos obtenidos en la prueba del factor de riesgo de estrés realizado. ........................................................................................................................ 21
6.5 Estrategias para mitigar los factores de riesgo psicosocial en el restaurante AUTOR. .. 23
7. CONCLUSIONES Y RECOMENDACIONES ..................................................................... 27
7.1 Conclusiones .................................................................................................................... 27
7.2 Recomendaciones ............................................................................................................ 28
8. REFERENCIAS....................................................................................................................... 30The innumerable challenges that organizations face make it very difficult to achieve self-sustainability over time. Therefore, it is essential to analyze the variables that establish a causal relationship, which may affect the mental health of workers and, therefore, the difficulty of companies in achieving the high competitive levels required in a globalized world.
Among countless variables that affect the mental health of workers and organizations, it was determined to carry out an analysis of the psychosocial risk factors to which workers at the AUTOR Restaurant may be exposed. Likewise, the analysis will fundamentally focus on the intra-work, non-work and stress conditions components, through the application of different tests that will allow quantitative results to be obtained in order to establish the degree of impact that they may have on their mental health and that may make it difficult to compliance with organizational objectives.
Finally, it was possible to determine results in the analysis of psychosocial risk factors such as: workload and pace of work, interpersonal relationships, work stress, participation and control, interpersonal relationships, characteristics of housing and environment, travel to housing and vice versa, economic situation and family relationships, among others.EspecializaciónEspecialista en Seguridad y Salud en el Trabaj
Observatorio de bibliometría y cienciometría USTA Métricas de autor FICHA BIBLIOMÉTRICA Fabian López Guzmán
No full textInforme de las métricas de autor del Dr. Fabian López Guzmán de las publicaciones
indexadas en Google Académico cuyo objetivo es entregar un insumo para el
fortalecimiento de las capacidades y potencialidades de los autores de la
Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics Fabian López Guzmán of the publications indexed in
Google Scholar whose objective is to provide an input for the strengthening of the
capacities and potentialities of the authors of the Santo Tomás University in the
positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Observatorio de bibliometría y cienciometría USTA Métricas de autor FICHA BIBLIOMÉTRICA Carlos Alberto Cárdenas Sierra
No full textInforme de las métricas de autor del Dr. Carlos Alberto Cárdenas Sierra de las
publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo
para el fortalecimiento de las capacidades y potencialidades de los autores de la
Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicaciones.Report of the author metrics Carlos Alberto Cárdenas Sierra of the publications
indexed in Google Scholar whose objective is to provide an input for the
strengthening of the capacities and potentialities of the authors of the Santo Tomás
University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Observatorio de bibliometría y cienciometría USTA Métricas de autor FICHA BIBLIOMÉTRICA David Valencia Villamizar
No full textInforme de las métricas de autor del Dr. David Valencia Villamizar de las
publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo
para el fortalecimiento de las capacidades y potencialidades de los autores de la
Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics David Valencia Villamizar of the publications indexed in
Google Scholar whose objective is to provide an input for the strengthening of the
capacities and potentialities of the authors of the Santo Tomás University in the
positioning and visibility of their publicationshttp://unidadinvestigacion.usta.edu.c
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