2,147 research outputs found
3D Technology in Prosthetic Care: Enhancing Accessibility in Sierra Leone
No full textContains fulltext :
323964.pdf (Publisher’s version ) (Open Access)Radboud University, 22 oktober 2025Promotores : Maal, T.J.J., Grobusch, M.P. Co-promotores : Brouwers, L., Leijendekkers, R.A.273 p
Treatment of imported severe malaria with artesunate instead of quinine - more evidence needed?
No full textTreatment of imported severe malaria with artesunate instead of quinine--more evidence needed? Cramer, J.P.; López-Vélez, R.; Burchard, G.D.; Grobusch, M.P.; de Vries, P.J
Automated malaria diagnosis using pigment detection
No full textSeveral new methods of malaria diagnosis have recently been developed, but these all rely on clinical suspicion and, consequently, an explicit clinical request. Although some methods lend themselves to automation (eg. PCR), no technique can yet be used for routine clinical automated screening. Detection of birefringent haemozoin has been used to diagnose malaria since the turn of the 20th century. A new generation of full blood count analysers, used widely in clinical laboratories, have the potential to detect haemozoin in white blood cells and probably erythrocytes. Thomas Hänscheid, Emilia Valadas and Martin Grobusch here describe this novel technique for malaria diagnosis and discuss its potential application
Detergency in Liquid CO2
No full textIn this dissertation we study Detergency in liquid Carbon Dioxide. Detergency is the cleaning performance of additives, surfactants in particular, in washing fluids. Liquid CO2 is under consideration, for environmental and toxicological reasons, to replace perchloro-ethylene as the solvent in textile dry cleaning technology. Inherent problems of such a transition were confronted with the methodology of chemical engineering design. The Basic Cycle of Design (BCD) approach was used as a pathway for designing a detergent. The BCD also establishes the structural framework of the thesis, which can, therefore, be read as records from a successful product engineering project, in which an effective detergent has been designed for a new dry cleaning solvent. The Dynamic Detergency Model (DDM), which succeeds to explain the role of surfactants in the washing operation, is used as a rational starting point for the design of a detergent in liquid CO2. According to this model, such a surfactant must be: sparingly soluble in the solvent, surface-active and able to form micelles in the solution. The different experiments carried out (solubility, interfacial-tension and dye solubilisation measurements), show that a number of molecules of the homologous polyoxyethylene/alkane series, generally described by the shorthand formula CiEj did indeed behave as surfactants and can be then considered detergents for liquid CO2. In the technical evaluation of the detergents, at laboratory as well as at semi-pilot scale, high washing performances were obtained. They are, indeed, as good for dry cleaning textiles as the present perchloro-ethylene (Perc) technology.Applied Science
'Her Irish Heritage' : Annie M.P Smithson and autobiography
No full textThis paper examines some aspects of the work of Annie M.P. Smithson, the author of 21 romance novels between 1917 and 1946. Her attitudes towards women, religion and politics are explored, and the importance of autobiography in her fiction discussed.Cet article analyse divers aspects de l'oeuvre d'Annie M.P. Smithson, l'auteur de vingt et un romans 'romanesques' publiés entre 1917 et 1946. Il étudie son attitude concernant les femmes, la religion, la politique, ainsi que le rôle de l'autobiographie dans sa fiction.Walsh Oonagh. 'Her Irish Heritage' : Annie M.P Smithson and autobiography. In: Études irlandaises, n°23-1, 1998. pp. 27-42
Il ruolo della linguistica in un'iniziativa di internazionalizzazione
No full textThe author deals with the role of linguistic sciences and language teaching in the internationalization project of an e-learning Specialization Course
Assessing the Consequences of Stigma for Tuberculosis Patients in Urban Zambia
No full textAssessing the consequences of stigma for tuberculosis patients in urban zambia Cremers, A.L.; de Laat, M.M.; Kapata, N.; Gerrets, R.P.M.; Klipstein-Grobusch, K.; Grobusch, M.P. Published in: PLoS ONE DOI: 10.1371/journal.pone.0119861 Link to publication Citation for published version (APA): Cremers, A. L., de Laat, M. M., Kapata, N., Gerrets, R., Klipstein-Grobusch, K., & Grobusch, M. P. (2015). Assessing the consequences of stigma for tuberculosis patients in urban zambia. PLoS ONE, 10(3), [e0119861]. https://doi.org/10.1371/journal.pone.0119861 General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. Abstract Background Stigma is one of the many factors hindering tuberculosis (TB) control by negatively affecting hospital delay and treatment compliance. In Zambia, the morbidity and mortality due to TB remains high, despite extended public health attempts to control the epidemic and to diminish stigma. Study Aim To enhance understanding of TB-related stigmatizing perceptions and to describe TB patients' experiences of stigma in order to point out recommendations to improve TB policy. Methods We conducted a mixed method study at Kanyama clinic and surrounding areas, in Lusaka, Zambia; structured interviews with 300 TB patients, multiple in-depth interviews with 30 TB patients and 10 biomedical health workers, 3 focus group discussions with TB patients and treatment supporters, complemented by participant observation and policy analysis of the TB control program. Predictors of stigma were identified by use of multivariate regression analyses; qualitative analysis of the in-depth interviews, focus group discussions and participant observation was used for triangulation of the study findings. Results We focused on the 138/300 patients that described TB-related perceptions and attitudes, of whom 113 (82%) reported stigma. Data Availability Statement: All relevant data from the TBAC study are contained within the paper. Additional data will be made available by our first author. The original data contain information which may lead to the identification of study subjects and in order to protect their privacy, a request to gain access to the original data is needed. Funding: No specific funding was received for this study other than the personal grants for ALC specified below. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. both among children and adults and included low self-esteem, insults, ridicule, discrimination, social exclusion, and isolation leading to a decreased quality of life and social status, non-disclosure, and/or difficulties with treatment compliance and adherence. Women had significantly more stigma-related problems than men. Conclusions The findings illustrate that many TB patients faced stigma-related issues, often hindering effective TB control and suggesting that current efforts to reduce stigma are not yet optimal. The content and implementation of sensitization programs should be improved and more emphasis needs to be placed on women and children. Introduction Alongside biological, economic, and cultural barriers to effective tuberculosis (TB) control, stigma constitutes one of the major social factors causing hospital delay and hindering compliance among TB patients The importance of addressing stigma related to TB is illustrated by the fact that this disease is one of the major causes of death worldwide. Zambia ranks 29 th among the world's top TB countries identified by the World Health Organisation (WHO) having 427/100.000 incident TB cases in the year 2012. HIV co-infection rate is 61% and MDR-TB prevails in 0.3% of new Consequences of Stigma for Tuberculosis Patients in Urban Zambia PLOS ONE
Author Correction: Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction (Scientific Reports, (2017), 7, 1, (15364), 10.1038/s41598-017-15539-7)
No full textIn the original version of this Article, Martin C. J. Bootsma, Perry J. van Genderen, Abraham Goorhuis, Martin Grobusch, Nicky Molhoek, Astrid M. L. Oude Lashof, Ellen E. Stobberingh & Henri A. Verbrugh were incorrectly listed as the COMBAT consortium. This error has now been corrected in the HTML and PDF versions of the Article, and in the accompanying supplementary material
The influence of steady blowing and roughness on transitional separated boundary layers
No full textThis paper presents the results of a study between two types of forcing, namely steady blowing and a tripwire, on the control of laminar separated boundary layers. The analysis focuses on the differences in the transition process between these two types of forcing. This effect will be studied using direct numerical simulation. The main differences consists in the coherent structures formed during transition and the overall kinetic energy growth
Gusmani grecista
No full textThe author deals with the Roberto Gusmani's works about Ancient Greek language
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