1,721,002 research outputs found

    Analisi idro-geomorfometrica di alcuni bacini idrogeografici italiani

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    Nel presente lavoro sono riportati i risultati dell’analisi idro-geomorfometrica di 30 bacini fluviali italiani. Nel complesso, a partire dalle basi cartografiche e dai dati storici disponibili, è stato realizzato un ampio insieme di parametri descrittivi delle caratteristiche idrologiche, morfometriche e di erodibilità che, in diversa misura, possono contribuire alla dinamica del trasporto dei sedimenti. L’analisi è stata condotta utilizzando il toolset originale QMorphoStream, sviluppato in ambiente QGIS. I risultati presentati rappresentano il primo obiettivo di un programma di ricerca più ampio, finalizzato allo sviluppo di metodi e modelli di previsione del trasporto solido in sospensione dei corsi d'acqua italiani, per la stima del potenziale apporto sedimentario dai bacini idrografici ai litorali, nell'ambito degli scenari di cambiamento climatico e di rischio di erosione/sommersione di alcuni tratti delle coste italiane.In the present paper, the results of the hydro-geomorphometric analysis of 30 Italian river basins are reported. Basing on digital cartographic sources and available data records, a broad set of variables was built up describing hydrologic, morphometric and erodibility features that may have a role in river sediment transport and delivery. The analysis was performed using the original toolset QMorpho-Stream, developed in QGIS environment. The results hereby presented are the first step of a wider research program aimed at developing methods and models for the estimate of the potential sediment supply from river basins to the coasts, in the framework of current climate change scenarios and the risk of erosion/submersion of some Italian coastal areas

    Microscopia elettronica a scansione (SEM) nella comunicazione clinica anatomopatologica e medicolegale

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    la comunicazzione clinica è un valore aggiunto alla buona pratica nell'ambito delle multiformi attività diagnostich

    Diagnostic performance of a tear protein panel in early dry eye

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    PURPOSE: To evaluate the tear protein pattern in patients with recent subjective symptoms of dry eye (DE) and with poor distinctive DE clinical signs. METHODS: One hundred sixty patients suspected of suffering from mild to moderate DE according to the Dry Eye Workshop (DEWS report 2007) severity grade and 45 matched normal volunteers were included in the study. Subjective symptom score (Ocular Surface Disease index score), Schirmer test I, tear film break-up time, cornea and conjunctiva staining (National Eye Institute score); and tear protein analysis were performed. Statistical evaluation of data was performed with Mann-Whitney unpaired and Student t tests, (significance p<0.05). Correlations between variables were evaluated by using Pearson's (r) or Spearman's (ρ) correlation coefficients. Thresholds were selected from receiver operating curves; sensitivity, specificity, likelihood ratio (LR+), and positive predictive values were calculated for each protein. The combination of variables was carried out by univariate analysis, representing the best combination of tests for early DE diagnosis. RESULTS: TOTAL PROTEIN CONTENT (TP) AND THE FOLLOWING PROTEINS WERE RECOGNIZED IN ALL SAMPLES: lysozyme-C (LYS-C), lactoferrin (LACTO), tear lipocalin 1 (LIPOC-1), zinc-alpha-2-glycoprotein (ZAG-2), transferrin (TRANSF), and exudated serum albumin (ALB). A statistically significant decrease was demonstrated between normal subjects and patients with DE (mg/ml, mean±SD) for TP (9.89±2.28 versus 6.44±2.1), LYS-C (3.06±1.07 versus 2.15±0.78), LIPOC-1 (1.71±0.52 versus 0.98±0.5), ZAG-2 (0.43±0.24 versus 0.25±0.2), TRANSF (0.9±0.6 versus 0.33±0.3), and LACTO (2.11±0.74 versus 1.47±0.76), while an increase was found for ALB (0.21±0.5 versus 0.94±1.28). LIPOC-1 and ZAG-2 were strongly correlated to tear film break-up time. The proteins were related to the DEWS severity grade. Changes in each protein were a better predictor of early DE than were clinical variables; TP, LIPOC-1, and ALB exhibited the highest diagnostic performance either alone (LR+ 16.7, 12.3, 4.7, respectively) or when combined in a univariate analysis (LR+: 41.8, positive predictive value: 99.9). CONCLUSIONS: Our results demonstrated in tears from patients with early DE a significant reduction in tear protein content as a whole, associated with a decrease in proteins with antibacterial and protective functions. A decrease in proteins with lipid binding properties and an increase in inflammatory-related proteins were also shown. Changes in the abundance of a panel of tear proteins with divergent functions was found to better diagnose early DE than did conventional clinical tests

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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