832 research outputs found
Metabolic dysfunction-associated steatotic liver disease a multisystem disease: assessing the cost effectiveness of pharmacotherapies
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Mayor Dore Apologizes poster, Seattle, 1936
No full textSeattle has a long history of labor radicalism dating back into the 19th century. The 1930s saw a new burst of radical labor activism, with large scale strikes and boycotting that strengthened local labor unions representing longshoremen, woodworkers, truck drivers, and machinists. As unions grew in power, so did criticism of many union leaders who utilized heavy-handed methods of recruitment and negotiation. On October 13, 1936, Gladys A. (Mead) Selvin (1894-1984), a secretary at and wife of the owner of Seattle newspaper "The Business Chronicle," led a group of more than 500 women in a march to the state capital in Olympia. The women delivered a petition imploring Washington Governor Clarence D. Martin (1886-1955) to prosecute labor leaders guilty of racketeering and intimidating workers and businessmen. These women became known as the Women of Washington State-wide Committee, and continued to advocate for state legislation to curb the power of labor unions into 1937.
The broadside pictured here reprints comments condemning the committee and its members made in the weeks following the march by Seattle Mayor John Dore (1881-1938). The poster uses the negative remarks of Mayor Dore and Governor Martin to mobilize women across the state to unite against the racketeering and "unbridled radicalism" of Mayor Dore and his allies.Caption information source: "Dore, John Francis (1881-1938)," by David Wilma, HistoryLink.org Essay 2720.
Caption information source: "Seattle Labor History Highlights," by James Gregory, The Seattle Civil Rights and Labor History Project, University of Washington.
Caption information sources: The Seattle Daily Times, "Delegation to Petition Martin for Prosecution," Seattle Daily Times, October 13, 1963, p. 1; and "Mayor Dore Versus Women of Washington," October 26, 1936, p. 1.1 broadside: b&w; 17.5 x 23 in
Intertextuality and failed taboo humour in advertising
No full textHumour is often exploited in advertising to enhance the positive image of a brand or corporate company, as well as to promote products or services. Advertisers seek the involvement of the audience via covert or overt references that, in their opinion, may trigger humour and, hypothetically, result in a positive customer response. However, using intertextual humour in advertising can sometimes be risky because, even though the ideal interlocutor is supposed to be familiar with the humorous reference the author alludes to, the latter can never be certain of whether it will be favourably received. The matter is further complicated if the advert relies on references that play on taboo or transgressive topics, which some may find humorous while others will consider distasteful. After all, humour is a phenomenon that varies according to individual cultures and historical time, as well as in terms of how it is perceived and whether it is appreciated. In this context, this study focuses on the use of intertextual taboo humour in adverts and campaigns that exploit both verbal and non-verbal texts. It particularly explores the reasons for the target clientele’s reaction, which has had a boomerang effect on the brand and company itself. The suggested hypothesis is that the simultaneous exploitation of verbal and non-verbal intertextual references (consciously or unconsciously) activates multiple targets and scripts that cause the intended humour to fail in its scope
JEAN VALJEAN’S DILEMMA AND UTILITARIAN ETHICS
No full textThis work is an evaluation, through the criterion of utilitarian ethics, of the resolution
of an intense moral dilemma in Victor Hugo’s 1862 masterpiece, Les Misérables. The
dilemma is faced by the main protagonist Jean Valjean. Valjean, a former convict, has
redeemed his life and has become mayor of a French city under an assumed name. Years
later, he learns that someone else has been erroneously arrested as him, and Valjean is
faced with the choice of letting this man be convicted and sent to a horrible punishment
in the galleys, or revealing his identity and facing reimprisonment himself in order to
save him. In doing the latter, he acts according to the demands of deontological ethics,
for which the author of the novel explicitly commends him. Nevertheless, this work avers
that in making the latter choice, Valjean, in terms of utilitarian ethics, acts immorally.
It affirms this by showing, through the writings of Jeremy Bentham, that in morally
evaluating an action in utilitarian ethical terms, the happiness and unhappiness caused
to everyone affected by his act must be quantified and balanced against each other.
Due to the effect that the loss of their benevolent mayor has on other characters, the
saving of one individual cannot be seen to be productive of the greatest good. This work
then examines possible objections to this evaluation and through writers on ethics and
Bentham himself, shows that these objections do not invalidate the central argument of
the work
Vaccine Apartheid: A Human Rights Analysis of COVID-19 Vaccine Inequity (Working paper)
No full textIn this paper, we analyse vaccine inequity under international human rights law. In Part 1, we introduce the currently available COVID-19 vaccines, before discussing causes and consequences of vaccine inequity, as well as current efforts to expand global vaccine access. In Part 2, we turn to explain the relevant, including extraterritorial, obligations of states regarding human rights to health, life, and equitable access to the benefits of technology. In light of those obligations, we assess the human rights compatibility of the following circumstances which hinder and facilitate vaccine access: embargoes on vaccines; national procurement and vaccine hoarding; and vaccine aid. Part 2 concludes with a short discussion of the possible human rights responsibilities of the entities that own the vaccines, multinational pharmaceutical companies. In Part 3, we analyse proposals to waive global intellectual property rights in respect of COVID-19 vaccines, and whether assent to such a waiver is demanded under international human rights law. Part 4 concludes this paper.Full Tex
Skriveni sukobi sa neortodoksnim prevodiocem: doprinosi Dore Gabe jevrejskoj štampi u Bugarskoj
No full textThe article presents the contributions of Dora Gabe to the Jewish newspaper „Maccabi“, published in Sofia from 1920 to 1940. She cooperated with the paper both as a translator and an original author. Gabe’s texts in „Maccabi“ have not been reprinted and are almost forgotten. This factor explains why they need to be revisited. First, I trace Edmond Fleg’s influence on Gabe’s ideas on Jewish identity, as the poet is a vivid promoter and a keen translator of Fleg’s work. Then this topic is represented in light of a hidden conflict between other journalists from Maccabi circles and Dora Gabe. The main argument of the text is that Gabe was criticized not only for assimilating into Bulgarian society but mostly because of her feminist ideas and her original, paradoxically anti-national viewpoints on the Zionist movement.U članku su predstavljeni doprinosi Dore Gabe jevrejskom listu „Makabi“, koji je izlazio u Sofiji od 1920. do 1940. godine. Ona je sa listom sarađivala i kao prevodilac i kao originalni autor. Tekstovi Dore Gabe u Makabiju nisu preštampani i skoro su zaboravljeni. Ovaj faktor objašnjava zašto ih treba ponovo razmotriti. Prvo, pratim uticaj Edmonda Flega na ideje Dore Gabe o jevrejskom identitetu, pošto je pesnikinja živopisan promoter i strastveni prevodilac Flegovog dela. Zatim je ova tema predstavljena u svetlu skrivenog sukoba između ostalih novinara iz Makabijevih krugova i Dore Gabe. Glavni argument teksta je da je Gabe kritikovana ne samo zbog asimilacije u bugarsko društvo, već najviše zbog njenih feminističkih ideja i njenih originalnih, paradoksalno antinacionalnih stavova o cionističkom pokretu.Tema ovog broja: "Balkanske Jevrejke" (the topic of this issue: "Balkan Jewish women")
HCC incidence after hepatitis C cure among patients with advanced fibrosis or cirrhosis: A meta-analysis
No full textBackground and aims: HCV cure reduces but does not eliminate the risk of HCC. HCC surveillance is recommended in populations where the incidence exceeds 1.5% per year. In cirrhosis, HCC surveillance should continue after HCV cure, although it is uncertain if this should be indefinite. For patients with advanced fibrosis (F3), guidelines are inconsistent in their recommendations. We evaluated the incidence of HCC after HCV cure among patients with F3 fibrosis or cirrhosis. Approach and results: This systematic review and meta-analysis identified 44 studies (107,548 person-years of follow-up) assessing the incidence of HCC after HCV cure among patients with F3 fibrosis or cirrhosis. The incidence of HCC was 2.1 per 100 person-years (95% CI, 1.9-2.4) among patients with cirrhosis and 0.5 per 100 person-years (95% CI, 0.3-0.7) among patients with F3 fibrosis. In a meta-regression analysis among patients with cirrhosis, older age (adjusted rate ratio [aRR] per 10-year increase in mean/median age, 1.32; 95% CI, 1.00-1.73) and prior decompensation (aRR per 10% increase in the proportion of patients with prior decompensation, 1.06; 95% CI, 1.01-1.12) were associated with an increased incidence of HCC. Longer follow-up after HCV cure was associated with a decreased incidence of HCC (aRR per year increase in mean/median follow-up, 0.87; 95% CI, 0.79-0.96). Conclusions: Among patients with cirrhosis, the incidence of HCC decreases over time after HCV cure and is lowest in patients with younger age and compensated cirrhosis. The substantially lower incidence in F3 fibrosis is below the recommended threshold for cost-effective screening. The results should encourage the development of validated predictive models that better identify at-risk individuals, especially among patients with F3 fibrosis
Homossexual: pecador e un-African? A tensão em torno da homossexualidade masculina em “The day he came” de Amatesiro Dore
No full textDespite the still scarce discussion in Brazil on queer issues in Africa, different literary works aim to represent queer Africans today, among which is the short story collection Queer Africa 2, where we find Amatesiro Dore’s “The day he came,” the corpus of this paper. Therefore, we intend to analyze Dore’s short story based on the interaction between the world of art and the world of life, seeking to understand the context of homosexuality in Nigeria, the fictional space chosen by Dore and the country where homosexuality is criminalized, and its relation to discourses of religion (sin), law (crime) and tradition (un-Africannes), based on the voices of mostly African intellectuals who focus on the topic. We concluded that the author, even establishing the fictional world in Nigeria, prioritizes religion discourse over legal or traditional issues as the main source of the conflicts the protagonist Peter lives.Apesar de haver, no Brasil, uma discussão ainda escassa sobre as questões queer em África, várias obras literárias buscam representar o ser africano queer na contemporaneidade. Entre elas, está a coletânea de contos Queer Africa 2, em que se encontra “The day he came” de Amatesiro Dore, corpus deste trabalho. Este artigo busca, dessa forma, trazer uma análise do conto pautada na interação entre mundo da arte e mundo da vida, buscando compreender o contexto da homossexualidade na Nigéria, espaço ficcional escolhido por Dore e país onde a homossexualidade é criminalizada, e sua relação com o discurso religioso (pecado), legal (crime) e tradicional (un-Africannes) a partir das vozes, em sua maioria, de intelectuais africanos que se debruçam sobre o tema. Verificou-se que, no conto, o autor, mesmo estabelecendo o mundo ficcional na Nigéria, prioriza o discurso religioso e não a questão legal ou tradicional como a fonte principal dos conflitos vividos pelo protagonista Peter
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