1,720,956 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Randomized trial of combination therapy in relapser or non-responder HCV patients
No full textThe combination of interferon (IFN) and ribavirin (RIBA) has efficacy in previously non-responder (NR) or relapser (REL) HCV patients. However, the effect of increased dose of IFN associated with RIBA is not known. The aim of this study was to evaluate different IFN dose in combination with RIBA in NR or REL patients.We randomised 102 patients with biopsy-proven chronic HCV hepatitis to receive either 3 or 5 MU of recombinant IFN three times a week and RIBA (1000-1200 mg/die) for 6 months and followed for additional 6 months. Patients with cirrhosis were excluded from the study. The treatment was stopped at 4 months for cases with abnormal ALT levels and HCV-RNA positivity. The patients with undetectable HCV-RNA and normal ALT at the end of the treatment were defined as complete responders (CR), and those with the same state the end of follow-up were defined as long-term responders (LTR). There were 52 non-responders and 58 relapsers to prior IFN treatment. Mean age and histological severity of liver disease was comparable in the four groups. Four patients (4%) dropped out because skin lesions or severe anaemia. A large fraction of patients (68 cases, 64 %) developed mild anaemia but therapy was not discontinued. Full follow-up data are available on 102 cases.
IFN 3 MU 3 times a week End of treatment End follow-up
25 previous NR 4 CR (16%) 21 NR (84%) 4 LTR (16%)
25 previous REL 15 CR (60%) 10 NR (40%) 12 LTR (46%)
IFN 5 MU 3 times a week
27 previous NR 18 CR (66%) 9 NR (33%) 12 LTR (44%)
25 previous REL 22 CR (88%) 3 NR (12%) 17 LTR (68%)
There was a statistically significant difference between previous REL and NR either at the end of the treatment and of the follow-up. There was difference between previous REL subjects randomised to receive 3 or 5 MU at the end of the therapy but not at the end of the follow-up. On the contrary, in previous NR an increased dose of IFN obtained a statistically (p<0.03) improvement of responses. Interestingly, a fraction (10-40%) of previous REL became NR at the combination therapy, this could indicate the appearance of viral quasispecies or genotypes highly resistant to antiviral drugs. In conclusions, when used in combination with RIBA, 5MU of IFN is able to enhance the response rate compared with 3MU, especially in previous NR. In NR or REL cases after combination therapy, new therapeutical approaches are needed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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