3,556 research outputs found

    Structural and functional studies on bovine and human brain inositol monophosphatase

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    SIGLEAvailable from British Library Document Supply Centre- DSC:DX180405 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Past veterinarians in South Africa

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    An alphabetical list containing short biographies of all deceased South African veterinarians up to 1990.[compiled by] P.J. (Bill) PosthumusVolume 1: AL -- Volume 2: M-ZAlso available in print http://137.215.9.20/record=b1893606ab2013ab201

    Open brief aan den WelEdel. Gestr. Heer P.J. Joubert

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    leyds-70-7201.pdf created from original pamphlet in the WJ Leyds Collection held in the Africana Section of the Stellenbosch University Library and Information Service.Dutch open letter to P.J. Joubert concerning a railroad concession granted to the author and two of his friends in 1885

    Design, Modeling and Simulation of a 52MHz MEMS Gyroscope Device in 1.5um SOI

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    In this thesis , a simulation model of a MEMS gyroscope is presented. The model enables mode matching and analysis of the dynamic behavior of a gyroscope. Furthermore, the model allows the optimization the design parameters of the gyroscope. The simulated gyroscope operates at a frequency of 52MHz with amplitudes of 10nm and quality factor of 50,000. Finally, the drive mode measurements are presented at different bias voltages.Microelectronics & Computer EngineeringElectrical Engineering, Mathematics and Computer Scienc

    Het gemeentelijk Investeringsraadsel: Het verband tussen gemeentelijke investeringen en lokale welvaartsontwikkeling

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    Dit proefschrift gaat over de vraag in hoeverre in Nederland de lokale welvaartsontwikkeling wordt bepaald door de gemeentelijke investeringsinspanning. Op project niveau is meestal wel het een en ander bekend over de maatschappelijke effecten, maar over de impact van de totale investeringsinspanning ontbreekt zowel fundamentele als toepasbare kennis. Het is een raadsel dat nog opgelost dient te worden. De doelstelling van dit proefschrift is daaraan een bijdrage te leveren.Housing System

    Coupled thermo–hydro–mechanical processes for the Dutch radioactive waste repository

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    Disposal of spent nuclear fuel and long lived radioactive waste in deep clay geological formations is one of the promising options worldwide. In this concept of the geological disposal system, the Boom Clay is considered as a potential host rock when designing a generic waste repository in the Netherlands. For design and evaluation of a repository for geologic disposal of nuclear wastes one of its principal concern is the thermal loading. High-level radioactive waste and spent fuel generate considerable amounts of heat. When those waste types are disposed in a geological repository the elevated thermal effect on the behaviour of soils surrounding nuclear waste disposal give rise to change in hydraulic and mechanical properties is a significant factor for repository design. Understanding these time-dependent phenomena processes in relation to both the effects of pore water dissipation and of the thermal expansion is essential for reliably assessing repository performance and evaluating the safety case. This paper presents some of the investigation on the thermal processes with emphasis on the coupled Thermo-Hydro- Mechanical (THM) processes for the disposal concept of a radioactive waste disposal facility, in Boom Clay at a depth of about 500m.Geo-engineerin

    Probabilistic performance assessment of a deep tunnel for a radioactive waste repository in French COx claystone

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    A preliminary probabilistic study of the stability of a circular drift excavated for a radioactive waste repository in the French Callovo-Oxfordian claystone is presented and discussed. An analytical mechanical model assuming isotropic elastic behaviour and linear plastic softening was used. Particular emphasis here is placed on the uncertainty of mechanical property values. The test results from several laboratories showed considerably variable property values and they have been interpreted statistically in this investigation. The obtained statistical results were used in a Monte Carlo framework. The performance of the drift was evaluated in terms of the probability of threshold exceedance in the extent of the plastic zone.Geo-engineerin

    Achteraf bekeken: Architectuur in Suriname 1951 tot 1969: Bouwwerken ontworpen door ir. P.J. Nagel (1921-1997)

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    Dit boek bestaat hoofdzakelijk uit foto’s van bouwwerken in Suriname, ontworpen door ir. Peter Jacobus Nagel in de periode 1951-1969. Ingenieur P.J. Nagel is afgestudeerd aan de Technische Hogeschool Delft. In dit boek wordt beschreven het leven van Nagel: zijn studietijd, eerste werkkring op Aruba, leven en werken als zelfstandig architect in Suriname van 1951 tot 1963 en tot slot zijn activiteiten in- en vanuit Nederland

    Cementbetonnen plaatbekledingen op oevers en dijken, bundeling van artikelen uit de vakpers 1990-1991

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    CUR; Proefproject: Open colloidaal beton a/s dijkbekleding; PT civiele techniek, april 1990. Burger, A.M., Eversdijk, P.J. en Hendriksma, A.M.; Open cementbeton toegepast a/s bekleding voor dijken; Zeewering Breskens, proefproject voor colloidaal beton; Land + Water, mei 1990. Burger, A.M., Eversdijk, P.J. en Hendriksma, A.M.; Colloidaal beton weerstaat zware storm en hoge golven; De praktijk van open cementbeton a/s Plaatbekleding; Land + Water, juni 1990. CUR; Cementbetonnen plaatbekledingen op dijken; Proefprojecten CUR; Civiele Techniek, No4, 1990. Vrieze, C.G. de; Betonnen dijken, groen a/s gras; Proeven met colloidaal beton voor begroeide rivierdijken; Land + Water No.6, juni 1991. Eversdijk, P.J. en Fase, A.G.; Breuksteen met colloidaal beton pakt rivierdijken goed in; Proefproject Opijnen in Julianakanaal; Land + Water No. 7/8, augustus 1991. Rijke, W.G. de en Burger, A.M.; Cementbetonnen plaatbekledingen op dijken en oevers; Praktische ontwerpmethode (1); Civiele Techniek, jaargang 46, No.3, 1991. Rijke, W.G. de en Burger, A.M.; Cementbetonnen plaatbekledingen op dijken en oevers theoretisch waterdicht; Praktische ontwerpmethode (2); Civiele Techniek, jaargang 46, No.4, 1991. CUR; oemonstratieproject open colloidaal beton Noordoostpolder; Civiele Techniek, No.3, 1991

    Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation

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    Computer simulations on a new model of the alpha1b-adrenergic receptor based on the crystal structure of rhodopsin have been combined with experimental mutagenesis to investigate the role of residues in the cytosolic half of helix 6 in receptor activation. Our results support the hypothesis that a salt bridge between the highly conserved arginine (R143(3.50)) of the E/DRY motif of helix 3 and a conserved glutamate (E289(6.30)) on helix 6 constrains the alpha1b-AR in the inactive state. In fact, mutations of E289(6.30) that weakened the R143(3.50)-E289(6.30) interaction constitutively activated the receptor. The functional effect of mutating other amino acids on helix 6 (F286(6.27), A292(6.33), L296(6.37), V299(6.40,) V300(6.41), and F303(6.44)) correlates with the extent of their interaction with helix 3 and in particular with R143(3.50) of the E/DRY sequence
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