1,721,112 research outputs found
Epidemiology of Guillain-Barré syndrome
No full textThis review focuses on recent epidemiological findings on Guillain-Barré syndrome regarding incidence, antecedent events related to the disease, prognosis and prognostic indicators, and treatment. Moreover, this review summarizes recent observations on clinical variants of Guillain-Barré syndrome and their relationship with the prevailing clinical presentation of the disease. The epidemiological observations which have advanced the understanding of the pathogenesis of Guillain-Barré syndrome are also discussed. © 2001 Lippincott Williams & Wilkins
Clinical infections and multiple sclerosis: contribution from analytical epidemiology
No full textEpidemiological studies have suggested that exogenous factors may play a role in the etiology of multiple sclerosis and that the environmental component may be viral, but, as yet, there is insufficient evidence to draw any definite conclusions concerning any of the viruses so far proposed. The case-control approach failed to give any definitive conclusion. While the frequency of each common childhood illness is not significantly different between cases and controls, there are more consistent data suggesting that cases do report a later age at infections: this applies particularly to measles, rubella, mumps and EBV infection. Several studies have proved that viral or bacterial infections or reactivations could trigger the clinical attacks in relapsing-remitting MS
Hirayama Disease: A Case of an Albanian Woman Clinically Stabilized Without Surgery
No full textHirayama Disease (HD) is a rare clinical condition that usually affects young people with preference for Asian males. It appears with unilateral distal amyotrophy or asymmetric bilateral amyotrophy of an upper limb which is to refer to an involvement of the spinal metamers C7-C8-T1. A clinical case of a female patient of Albanian nationality is described, with onset of the disease in adulthood and clinical and electrophysiological features suggestive of HD, without any characteristic imaging findings. Clinical investigations, EMG and radiological data facilitated the diagnosis and allowed the exclusion of degenerative forms of the motor neuron and radiculopathies. In this paper, we want to point out that the diagnosis of this pathology should be hypothesized even in the absence of characteristic epidemiological and imaging data
HLA and spino-cerebellar ataxia: study of a family
No full textIt has been suggested that there is more than one type of dominant spinocerebellar ataxia, at least one of them controlled by a gene near the HLA region. In the family examined, linkage analysis was performed on the gene controlling the disease and some genetic markers, including the HLA system: a strong linkage (P=.002) between the disease gene and HLA was found. The data presented further support claims of the existence of at least one HLA-linked form of spinocerebellar ataxia
Epidemiologia delle malattie cerebro-vascolari
No full textRevisione critica delle ricerche neuroepidemiologiche sulle patologie cerebrovascolari acute (ictus ischemici e emorragici): studi di incidenza, prevalenza, mortalità, sopravvivenza, fattori di rischio genetici e ambientali, approcci terapeutici
Abnormalities of fast-, middle-, long-latency auditory evoked potentials (0-400 ms) in Multiple Sclerosis
No full textA group of 20 normally hearing patients suffering from defined multiple sclerosis (MS) underwent a simultaneous recording of fast-, middle-, slow latency auditory evoked potentials (FMS). Abnormalities of fast potentials (0-10 ms) were found in one half of patients. Abnormalities of middle and slow components (10-400 ms) were found in 90% of patients. Out of 12 cases with normal or border-line fast potentials, 9 of them provided a definitely abnormal pattern of middle and slow latency potentials. Taking altogether FMS results yield a 95% identification rate of MS patients. Among the middle and slow latency potentials, remarkable abnormalities were most frequentely observable in the latency range of Nv-P1-N1 components (30-60 ms)
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
- …
