5,655 research outputs found
Identifying interactions in the time and frequency domains in local and global networks : a Granger causality approach
No full textBackground
Reverse-engineering approaches such as Bayesian network inference, ordinary differential equations (ODEs) and information theory are widely applied to deriving causal relationships among different elements such as genes, proteins, metabolites, neurons, brain areas and so on, based upon multi-dimensional spatial and temporal data. There are several well-established reverse-engineering approaches to explore causal relationships in a dynamic network, such as ordinary differential equations (ODE), Bayesian networks, information theory and Granger Causality.
Results
Here we focused on Granger causality both in the time and frequency domain and in local and global networks, and applied our approach to experimental data (genes and proteins). For a small gene network, Granger causality outperformed all the other three approaches mentioned above. A global protein network of 812 proteins was reconstructed, using a novel approach. The obtained results fitted well with known experimental findings and predicted many experimentally testable results. In addition to interactions in the time domain, interactions in the frequency domain were also recovered.
Conclusions
The results on the proteomic data and gene data confirm that Granger causality is a simple and accurate approach to recover the network structure. Our approach is general and can be easily applied to other types of temporal data
Physiotherapy management of lung cancer
No full text[Granger CL (2016) Physiotherapy management of lung cancer. Journal of Physiotherapy 62: 60–67
The corpus approach: a common way forward for Contrastive Linguistics and Translation Studies
No full textIn this introductory chapter, Granger traces the development of Contrastive Linguistics and Translation Studies over the last decades to the present day, focusing on the role of the computer corpus in giving new impetus to each field and bringing them closer together. She discusses the different types of monolingual and multilingual corpora being used in CL and TS research, proposing at the same time a common corpus terminology. She then relates the contribution of the different corpus types to the major research interests of each discipline, highlighting the complementarity of the research and calling for increased cross-fertilization and resource-pooling. She then examines the practical issues of corpus exploitation, with a review of corpus analysis tools of particular value for CL and TS and finally, the contribution of corpus-based CL and TS research in the teaching of foreign languages and translation
Open access self-archiving: An author study
No full textThis, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years. Use of institutional repositories for this purpose has doubled and usage has increased by almost 60% for subject-based repositories. Self-archiving activity is greatest amongst those who publish the largest number of papers. There is still a substantial proportion of authors unaware of the possibility of providing open access to their work by self-archiving. Of the authors who have not yet self-archived any articles, 71% remain unaware of the option. With 49% of the author population having self-archived in some way, this means that 36% of the total author population (71% of the remaining 51%), has not yet been appraised of this way of providing open access. Authors have frequently expressed reluctance to self-archive because of the perceived time required and possible technical difficulties in carrying out this activity, yet findings here show that only 20% of authors found some degree of difficulty with the first act of depositing an article in a repository, and that this dropped to 9% for subsequent deposits. Another author worry is about infringing agreed copyright agreements with publishers, yet only 10% of authors currently know of the SHERPA/RoMEO list of publisher permissions policies with respect to self-archiving, where clear guidance as to what a publisher permits is provided. Where it is not known if permission is required, however, authors are not seeking it and are self-archiving without it. Communicating their results to peers remains the primary reason for scholars publishing their work; in other words,
researchers publish to have an impact on their field. The vast majority of authors (81%) would willingly comply with a mandate from their employer or research funder to deposit copies of their articles in an institutional or subject-based repository. A further 13% would comply reluctantly; 5% would not comply with such a mandate
Progress of international hydrogen production network for the thermochemical Cu–Cl cycle
No full textThis paper presents recent advances by an international team which is developing the thermochemical copper–chlorine (Cu–Cl) cycle for hydrogen production. Development of the Cu–Cl cycle has been pursued by several countries within the framework of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. Due to its lower temperature requirements in comparison with other thermochemical cycles, the Cu–Cl cycle is particularly well matched with Canada's Generation IV reactor, SCWR (Super-Critical Water Reactor), as well as other heat sources such as solar energy or industrial waste heat. In this paper, recent developments of the Cu–Cl cycle are presented, specifically involving unit operation experiments, corrosion resistant materials and system integration.Atomic Energy of Canada LimitedOntario Research Excellence FundNatural Sciences and Engineering Research Council of CanadaUniversity Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs progra
ŻYCIE UKRYTE W SŁOWIE. "BEKSIŃSCY. PORTRET PODWÓJNY" MAGDALENY GRZEBIAŁKOWSKIEJ W ŚWIETLE POSTSTRUKTURALIZMU
No full textLife Hidden in Words. Magdalena Grzebiałkowska\u27s "Beksińscy. Portret podwójny" and Poststructuralism
The article analyzes Magdalena Grzebiałkowska\u27s biographical "Beksińscy. Portret podwójny" which focuses on the lives of Zdzisław Beksiński and Tomasz Beksiński. The author looks at the construction of the biography and its relationship to poststructuralism, which allows for an appreciation of the literary features of the book. He points to how the specificity of the content, language, a mode of narration in Grzebiałkowska\u27s book make it a full-fledged literary work itself. As such the book departs from a typical biographical scheme. Juxtaposing the book with poststructural ideas leads to the reconsideration of the role of the author in the process of shaping of a biographical narrative
Reviews
No full texturvey of corpora used in crosslinguistic studies and the uses to which such corpora can be put by CL and TS specialists, Granger also tries to remedy the problem of different labels by presenting a system common to both disciplines. Furthermore, 172 Granger recognizes limitations of corpus-based approaches, e.g. the lack of suitable corpora and/or the difficulty of (semi-)automatic retrieval: owing to these limitations, she claims that "[w]hat matters is the use of solid empirical data, whether electronic or not" (p. 23). While this is certainly true, it might be added that, even in cases where manual retrieval of data proves necessary, there are still advantages to using electronic, publicly available standard corpora, as this increases the comparability and replicability of studies. Granger highlights the need for better software tools, the potential importance of multilingual corpora to teaching, and the advantages of more cross-disciplinary co-operation. The topic of Stig Johans
Systems, methods and devices for the capture and hydrogenation of carbon dioxide with thermochemical Cu—Cl and Mg—Cl—Na/K—CO2 cycles
No full textSystems, methods, and devices for producing hydrogen and capturing CO2 from emissions combine both H2 production and CO2 capture processes in forms of thermochemical cycles to produce useful products from captured CO2. The thermochemical cycles are copper-chlorine (Cu—Cl) and magnesium-chlorine-sodium/potassium cycles (Mg—Cl—Na/K—CO2). One system comprises a Cu—Cl cycle, a CO2 capture loop, and a hydrogenation cycle. Another system comprises an Mg—Cl—Na/K—CO2 cycle and a hydrogenation cycle. Devices for hydrogen production, CO2 capture, hydrogenation, and process and equipment integration include a two-stage fluidized/packed bed, hybrid two-stage spray-fluidized/packed bed reactor, a two-stage wet-mode absorber, a hybrid two-stage absorber, and a catalyst packed/fluidized bed reactor
Clean hydrogen production with the Cu–Cl cycle – Progress of international consortium, I: Experimental unit operations
No full textAdvancement of the thermochemical copper–chlorine (Cu–Cl) cycle for hydrogen production is reviewed and discussed in this paper. Individual unit operations and their linkage into an integrated cycle are being developed by a Canadian consortium, as part of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. This paper focuses on the consortium’s latest advances on the Cu–Cl cycle, particularly with respect to hydrogen production with Canada’s Generation IV reactor, called SCWR (Super-Critical Water Reactor). Other heat sources may also be utilized for the Cu–Cl cycle, such as solar energy or industrial waste heat. In this first of two companion papers, recent developments in Canada’s nuclear hydrogen program are reported, specifically unit operation experiments of the Cu–Cl cycle and system integration. The following second companion paper will present system modeling with Aspen Plus, corrosion resistant materials, thermochemistry, safety, and reliability aspects of the Cu–Cl cycle.Atomic Energy of Canada LimitedOntario Research Excellence FundNatural Sciences and Engineering Research Council of CanadaUniversity Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs progra
Canada’s program on nuclear hydrogen production and the thermochemical Cu–Cl cycle
No full textThis paper presents an overview of the status of Canada’s program on nuclear hydrogen production and the thermochemical copper–chlorine (Cu–Cl) cycle. Enabling technologies for the Cu–Cl cycle are being developed by a Canadian consortium, as part of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. Particular emphasis in this paper is given to hydrogen production with Canada’s Super-Critical Water Reactor, SCWR. Recent advances towards an integrated lab-scale Cu–Cl cycle are discussed, including experimentation, modeling, simulation, advanced materials, thermochemistry, safety, reliability and economics. In addition, electrolysis during off-peak hours, and the processes of integrating hydrogen plants with Canada’s nuclear plants are presented.Atomic Energy of Canada LimitedOntario Research Excellence FundArgonne National Laboratory (International Nuclear Energy Research Initiative; U.S. Department of Energy)Natural Sciences and Engineering Research Council of Canada (NSERC)University Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs (CRC
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