1,357,977 research outputs found
The Transgenerational Consequences of the Interaction Between Humans and Molecules: Alcohol as a Cultural Artifact
This paper aims to offer some insights on the concept of socio-materiality from the perspective of neuroscientific research. The example that will be proposed is that of the neuropsychological effects of alcohol abuse at both individual and intergenerational levels
Porta Nuova Building, in L'architettura di Milano. La città scritta dagli architetti dal dopoguerra a oggi, a cura di M. Biraghi, A. Granato
Andrew Granato: A Memorial Tribute
The following is the text in memory of the late Andy Granato, professor in physics and materials science
L’architettura di Milano. La città scritta dagli architetti dal dopoguerra a oggi
L'architettura di Milano dal 1945 al XXI secolo rende la città unica in Italia per il respiro internazionale: attraverso 150 schede critiche, disegni e fotografie originali, si ripercorre la storia di una via italiana alla modernità. Un pool di autorevoli studiosi e progettisti esamina criticamente in questo volume gli edifici più significativi (edilizia residenziale, uffici, monumenti, chiese) "firmati” da celebri architetti italiani e stranieri che nel corso degli ultimi 75 anni hanno assegnato a Milano un ruolo importante nel panorama internazionale rendendola un "museo a cielo aperto" dell'architettura moderna e contemporanea. L'apparato fotografico di Sosthen Hennekam, il ridisegno delle piante degli edifici e le mappe della città per individuarli conferiscono al volume una qualità tecnica ed estetica
The Claustrum of the Pig: An Immunohistochemical and a Quantitative Golgi Study
Despite increasing interest in the claustrum (Cl) over the last decades, its function is still a puzzling problem. Among the experimental species of potential use in Cl research, the pig is considered an interesting model, because of the similarities of its brain with the corresponding cortical and subcortical human structures. The swine Cl presents a peculiar morphology, characterized by a wide posterior enlargement, ideal for physiological investigations. There is a wealth of data on general anatomy, cytoarchitecture, and chemo architecture of the Cl, but much less is known about the dendritic morphometry of its neurons. Dendritic length and branching pattern are key features to understand the organization of the microcircuitry, and thus the delineation of the structure–function relationships of the Cl. To this effect, we undertook (a) a quantitative study of the dendrites of the spiny neurons of the swine Cl, employing the Golgi staining; and (b) an immunohistochemical analysis to describe the distribution of the parvalbumin (PV)-immunoreactive interneurons throughout the same nucleus. Taken together, the results that we report here show that the dendritic architecture and the distribution of the PV expressing interneurons change when the Cl of this species changes its shape along the rostro-caudal axis, thus suggesting a potentially specific function for the large posterior puddle. Anat Rec, 2019. © 2019 Wiley Periodicals, Inc
Padiglione d'Arte Contemporanea (PAC)
Il PAC, realizzato a Milano da Ignazio Gardella nel 1954, occupa un ruolo d’eccezione nell’ambito della museografia italiana degli anni Cinquanta, è il primo intervento ad affrontare il tema di uno spazio espositivo di nuova costruzione in un paese che ha privilegiato la collocazione dei musei in edifici storici. L’edificio fissa temi di architettura che ritorneranno anche nelle esperienze di Albini, dei BBPR, di Scarpa: il rapporto tra città storica e architettura moderna, il ruolo del museo come luogo di identità collettiva e mette in scena un’idea differente dell’esporre non solo didattica ma esperienziale.The PAC, Designed by I. Gardella in Milan in 1954, has an exceptional place in the field of italian museum design of the 1950s
The Role of the Dust in Primeval Galaxies: A Simple Physical Model for Lyman Break Galaxies and Lyα Emitters
We explore the onset of star formation in the early universe, exploiting the observations of high-redshift LBGs and Lyα emitters (LAEs), in the framework of the galaxy formation scenario elaborated by Granato and coworkers, already successfully tested against the wealth of data on later evolutionary stages. Complementing the model with a simple, physically plausible recipe for the evolution of dust attenuation in metal-poor galaxies, we reproduce the LFs of LBGs and of LAEs at different redshifts. This recipe yields a much faster increase with galactic age of attenuation in more massive galaxies, endowed with higher SFRs. These objects have therefore shorter lifetimes in the LAE and LBG phases and are more easily detected in the dusty submillimeter-bright (SMB) phase. The short UV-bright lifetimes of massive objects strongly mitigate the effect of the fast increase of the massive halo density with decreasing redshift, thus accounting for the weaker evolution of the LBG LF, compared to that of the halo mass function, and the even weaker evolution between z~6 and z~3 of the LAE LF. The much lower fraction of LBGs hosting detectable nuclear activity, compared to SMB galaxies, comes out naturally from the evolutionary sequence yielded by the model, which features the coevolution of galaxies and active nuclei. In this framework LAEs are on the average expected to be younger, with lower stellar masses, more compact, and associated with less massive halos than LBGs. Finally, we show that the IGM can be completely reionized at redshift z~6-7 by massive stars shining in protogalactic spheroids with halo masses from a few times 1010 to a few times 1011 Msolar, showing up as faint LBGs with magnitude in the range -17<~M1350<~-20, without resorting to any special stellar IMF
A simple physical model for young galaxies in the early Universe
We present a simple physical model featuring an evolutionary link between Lyα emitting (LAE), Lyman break (LBG), sub-millimeter bright (SMB), and passively evolving galaxies, in the framework of the approach by Granato et al. (Astrophys. J. 600:580, 2004), according to which the evolution of massive galaxies is tied to the growth of the supermassive black holes at their centers. A key role in determining the properties of high-z galaxies is played by dust absorption. We model its evolution adopting a power-law relationship between UV extinction, star formation rate and metallicity, whose parameters are determined from a fit to the luminosity-reddening correlation for Lyman Break Galaxies, found by Shapley et al. (Astrophys. J. 562:95, 2001). The model yields quantitative relations between luminosities and basic physical quantities such as stellar and halo masses, star formation rates, galactic ages, metal abundances and dust extinction. It reproduces the luminosity functions (LFs) of LBGs and of LAEs at different redshifts, in the framework of the scenario that was previously shown to account for the wealth of observational data on SMB and passively evolving galaxies, as well as on high redshift quasars
Sede Generale Pirelli Real Estate
Breve saggio sul progetto di Gregotti Associati per la sede della Pirelli Real Estate nell'ambito del Progetto Bicocca a Milan
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