25,713 research outputs found
Portrait of Wm. L. Bowles, author of Fourteen sonnets, 1786 [picture] /
In: Album of William Romaine Govett, 1828-1847.; Inscriptions: "Author of Fourteen sonnets, 1786"--Below drawing.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s12-a1
Treatment of Metastatic Breast Cancer
Many newer agents in combination are being studied in the front-line treatment of women with HER2-positive metastatic breast cancer (MBC), but the story in the endocrine arena is more about the wise use of new strategies to overcome endocrine resistance, because no new antihormonal agents have been approved in the past decade. During his presentation at the NCCN 19th Annual Conference, Dr. William Gradishar explored what’s new in the treatment of MBC, focusing primarily on enhancing the effect of endocrine therapy to overcome resistance with newer targeted agents such as everolimus, reevaluating the role of rebiopsy on disease progression and measuring circulating tumor cells as a surrogate of response to treatment, and reviewing the effective treatment regimens for HER2-positive disease.</jats:p
Portrait of M. Faraday, author of Chemical manipulation [picture] /
In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s14-a1
Portrait of Anna Maria Hall, author of Buccaneer [picture] /
In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s11-a2
Portrait of G.R. Gleig, author of The subaltern [picture] /
In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s8-a1
Portrait of Geo. Cruikshank, author of Illustrations of time [picture] /
In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s9-a2
Treatment challenges for community oncologists treating postmenopausal women with endocrine-resistant, hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer
William J Gradishar Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA Abstract: Community-based oncologists are faced with challenges and opportunities when delivering quality patient care, including high patient volumes and diminished resources; however, there may be the potential to deliver increased patient education and subsequently improve outcomes. This review discusses the treatment of postmenopausal women with endocrine-resistant, hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in order to illustrate considerations in the provision of pertinent quality education in the treatment of these patients and the management of therapy-related adverse events. An overview of endocrine-resistant breast cancer and subsequent treatment challenges is also provided. Approved treatment options for endocrine-resistant breast cancer include hormonal therapies and mammalian target of rapamycin inhibitors. Compounds under clinical investigation are also discussed. Keywords: community oncologists, hormone receptor-positive advanced breast cancer, endocrine resistanc
John Soane, author of Design of buildings [picture] /
Title from inscription.; In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s16-a2
The Life and Letters of William Sharp and "Fiona Macleod"
"William Sharp (1855-1905) conducted one of the most audacious literary deceptions of his or any time. Sharp was a Scottish poet, novelist, biographer and editor who in 1893 began to write critically and commercially successful books under the name Fiona Macleod. This was far more than just a pseudonym: he corresponded as Macleod, enlisting his sister to provide the handwriting and address, and for more than a decade ""Fiona Macleod"" duped not only the general public but such literary luminaries as William Butler Yeats and, in America, E. C. Stedman.
Sharp wrote ""I feel another self within me now more than ever; it is as if I were possessed by a spirit who must speak out"". This three-volume collection brings together Sharp’s own correspondence – a fascinating trove in its own right, by a Victorian man of letters who was on intimate terms with writers including Dante Gabriel Rossetti, Walter Pater, and George Meredith – and the Fiona Macleod letters, which bring to life Sharp’s intriguing ""second self"".
With an introduction and detailed notes by William F. Halloran, this richly rewarding collection offers a wonderful insight into the literary landscape of the time, while also investigating a strange and underappreciated phenomenon of late-nineteenth-century English literature. It is essential for scholars of the period, and it is an illuminating read for anyone interested in authorship and identity.
Portrait of Sydney Smith, author of Plymley's letters on the catholics [picture] /
In: Album of William Romaine Govett, 1828-1847.; Also available online at: http://nla.gov.au/nla.pic-an4699386-s8-a2
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